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1.发明授权公开(公告)号：US08626297B2
公开(公告)日：2014-01-07
申请号：US12233810
申请日：2008-09-19
申请人： Kristen Jaax , Rafael Carbunaru , Mun Pook Lui , Todd K. Whitehurst , Andrew DiGiore , Brett Daniel Schleicher , Gregory Baldwin , Michael A. Moffitt , Jeffery Van Funderburk , Jim Makous
发明人： Kristen Jaax , Rafael Carbunaru , Mun Pook Lui , Todd K. Whitehurst , Andrew DiGiore , Brett Daniel Schleicher , Gregory Baldwin , Michael A. Moffitt , Jeffery Van Funderburk , Jim Makous
IPC分类号： A61N1/378
CPC分类号： A61N1/3787 , H02J7/025 , H02J7/047 , H02J50/10
摘要： Apparatus and methods for charging an implanted medical device.
摘要翻译： 用于对植入的医疗装置充电的装置和方法。
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公开(公告)号：US20110054518A1
公开(公告)日：2011-03-03
申请号：US12549174
申请日：2009-08-27
CPC分类号： A61N1/0539 , A61B17/3415 , A61B90/14 , A61B2017/3419 , A61B2090/103 , A61M2039/025 , A61M2039/0276 , A61M2039/0282
摘要： A burr hole sealing device for preventing brain shift during a stimulation lead implantation procedure is provided. The device includes a suction cup ring and a self-sealing membrane positioned within the aperture of the ring. The sealing device is attached adjacent to a burr hole and over a dura layer that is exposed in the bottom of the burr hole. The stimulation lead is disposed through the burr hole, through the membrane, through the dura layer and into brain tissue. The membrane is configured to allow the lead to pass therethrough while maintaining a tight seal around the diameter of the lead, thereby hindering leakage of cerebrospinal fluid out of the cranial cavity and maintaining a substantially fixed intracranial pressure. In one embodiment, the sealing device includes a syringe for adding fluid to, or removing fluid from, the cranial cavity in response to a detected change in intracranial pressure.
摘要翻译： 提供了一种用于在刺激引线植入程序期间防止脑移位的钻孔密封装置。 该装置包括吸盘环和位于环的孔内的自密封膜。 密封装置邻近毛刺孔并暴露在钻孔底部的硬脑膜层上。 刺激引线通过毛刺孔穿过膜，穿过硬脑膜层并进入脑组织。 膜被配置为允许引线通过，同时保持围绕铅直径的紧密密封，从而阻止脑脊液从脑腔中泄漏并保持基本上固定的颅内压。 在一个实施例中，密封装置包括用于响应于检测到的颅内压变化而将流体添加到颅腔或从头颅腔移除流体的注射器。
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3.发明申请公开(公告)号：US20090082835A1
公开(公告)日：2009-03-26
申请号：US12233810
申请日：2008-09-19
申请人： Kristen Jaax , Rafael Carbunaru , Mun Pook Lui , Todd K. Whitehurst , Andrew DiGiore , Brett Daniel Schleicher , Gregory Baldwin , Michael A. Moffitt , Jeffery Van Funderburk , Jim Makous
发明人： Kristen Jaax , Rafael Carbunaru , Mun Pook Lui , Todd K. Whitehurst , Andrew DiGiore , Brett Daniel Schleicher , Gregory Baldwin , Michael A. Moffitt , Jeffery Van Funderburk , Jim Makous
IPC分类号： A61N1/00
CPC分类号： A61N1/3787 , H02J7/025 , H02J7/047 , H02J50/10
摘要： Apparatus and methods for charging an implanted medical device.
摘要翻译： 用于对植入的医疗装置充电的装置和方法。
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公开(公告)号：US08313453B2
公开(公告)日：2012-11-20
申请号：US12549174
申请日：2009-08-27
IPC分类号： A61M5/00
CPC分类号： A61N1/0539 , A61B17/3415 , A61B90/14 , A61B2017/3419 , A61B2090/103 , A61M2039/025 , A61M2039/0276 , A61M2039/0282
摘要： A burr hole sealing device for preventing brain shift during a stimulation lead implantation procedure is provided. The device includes a suction cup ring and a self-sealing membrane positioned within the aperture of the ring. The sealing device is attached adjacent to a burr hole and over a dura layer that is exposed in the bottom of the burr hole. The stimulation lead is disposed through the burr hole, through the membrane, through the dura layer and into brain tissue. The membrane is configured to allow the lead to pass therethrough while maintaining a tight seal around the diameter of the lead, thereby hindering leakage of cerebrospinal fluid out of the cranial cavity and maintaining a substantially fixed intracranial pressure. In one embodiment, the sealing device includes a syringe for adding fluid to, or removing fluid from, the cranial cavity in response to a detected change in intracranial pressure.
摘要翻译： 提供了一种用于在刺激引线植入程序期间防止脑移位的钻孔密封装置。 该装置包括吸盘环和位于环的孔内的自密封膜。 密封装置邻近毛刺孔并暴露在钻孔底部的硬脑膜层上。 刺激引线通过毛刺孔穿过膜，穿过硬脑膜层并进入脑组织。 膜被配置为允许引线通过，同时保持围绕铅直径的紧密密封，从而阻止脑脊液从脑腔中泄漏并保持基本上固定的颅内压。 在一个实施例中，密封装置包括用于响应于检测到的颅内压变化而将流体添加到颅腔或从头颅腔移除流体的注射器。
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公开(公告)号：US08352035B2
公开(公告)日：2013-01-08
申请号：US12262789
申请日：2008-10-31
申请人： Brett Schleicher , Rafael Carbunaru , Todd K. Whitehurst , Kristen N. Jaax , Greg Baldwin , Andrew DiGiore
发明人： Brett Schleicher , Rafael Carbunaru , Todd K. Whitehurst , Kristen N. Jaax , Greg Baldwin , Andrew DiGiore
IPC分类号： A61N1/00
CPC分类号： A61N1/3754 , A61N1/37205 , A61N1/37235 , A61N1/375 , A61N1/3752 , A61N1/3787
摘要： Exemplary systems include a stimulator configured to be implanted within a patient, the stimulator having a body defined by at least one side surface disposed in between distal and proximal end surfaces, and a connector assembly configured to be coupled to the stimulator and extend parallel to the at least one side surface of the stimulator. The connector assembly is further configured to facilitate removable coupling of a lead having one or more electrodes disposed thereon to the stimulator.
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6.发明申请公开(公告)号：US20090192568A1
公开(公告)日：2009-07-30
申请号：US12339639
申请日：2008-12-19
申请人： Todd K. Whitehurst , Rafael Carbunaru , Kristen N. Jaax , Andrew DiGiore , Brett Schleicher , Greg Baldwin
发明人： Todd K. Whitehurst , Rafael Carbunaru , Kristen N. Jaax , Andrew DiGiore , Brett Schleicher , Greg Baldwin
CPC分类号： A61N1/36064 , A61N1/0529 , A61N1/0534 , A61N1/36082 , A61N1/37205 , A61N1/3756
摘要： Methods for treating seizures caused by brain stimulation include providing a stimulator, programming the stimulator with one or more stimulation parameters configured to treat a medical condition, applying at least one stimulus with the stimulator to a stimulation site within the brain of a patient in accordance with the one or more stimulation parameters, and monitoring the patient for a seizure caused by the at least one stimulus.
摘要翻译： 用于治疗由脑刺激引起的癫痫发作的方法包括提供刺激器，用刺激器编程配置成治疗医疗状况的一个或多个刺激参数，使用刺激器施加至少一个刺激到患者脑内的刺激部位， 一个或多个刺激参数，以及监测由至少一个刺激引起的癫痫发作的患者。
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公开(公告)号：US08600512B2
公开(公告)日：2013-12-03
申请号：US12339639
申请日：2008-12-19
申请人： Todd K. Whitehurst , Rafael Carbunaru , Kristen N. Jaax , Andrew DiGiore , Brett Schleicher , Greg Baldwin
发明人： Todd K. Whitehurst , Rafael Carbunaru , Kristen N. Jaax , Andrew DiGiore , Brett Schleicher , Greg Baldwin
IPC分类号： A61N1/00
CPC分类号： A61N1/36064 , A61N1/0529 , A61N1/0534 , A61N1/36082 , A61N1/37205 , A61N1/3756
摘要： Methods for treating seizures caused by brain stimulation include providing a stimulator, programming the stimulator with one or more stimulation parameters configured to treat a medical condition, applying at least one stimulus with the stimulator to a stimulation site within the brain of a patient in accordance with the one or more stimulation parameters, and monitoring the patient for a seizure caused by the at least one stimulus.
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8.发明授权Methods and systems of treating pancreatitis pain caused by sphincter of Oddi dysfunction 有权治疗由Oddi功能障碍括约肌引起的胰腺炎疼痛的方法和系统公开(公告)号：US08914112B2
公开(公告)日：2014-12-16
申请号：US12358002
申请日：2009-01-22
申请人： Todd K. Whitehurst , Rafael Carbunaru , Kristen N. Jaax , Andrew DiGiore , Brett Schleicher , Greg Baldwin , Roger Hastings
发明人： Todd K. Whitehurst , Rafael Carbunaru , Kristen N. Jaax , Andrew DiGiore , Brett Schleicher , Greg Baldwin , Roger Hastings
CPC分类号： A61N1/36007 , A61N1/36071 , A61N1/37205 , A61N1/37252
摘要： Methods and systems of treating a patient with pancreatitis pain include providing a stimulator, configuring one or more stimulation parameters to control sphincter of Oddi function, programming the stimulator with the one or more stimulation parameters, generating a stimulus configured to control sphincter of Oddi function with the stimulator in accordance with the one or more stimulation parameters, and applying the stimulus with the stimulator to one or more stimulation sites in accordance with the one or more stimulation parameters.
摘要翻译： 用于治疗患有胰腺炎疼痛的患者的方法和系统包括提供刺激器，配置一个或多个刺激参数以控制Oddi功能的括约肌，用所述一个或多个刺激参数编程所述刺激器，产生被配置为控制Oddi功能的括约肌的刺激， 所述刺激器根据所述一个或多个刺激参数，以及根据所述一个或多个刺激参数将刺激器刺激施加到一个或多个刺激部位。
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公开(公告)号：US08676322B2
公开(公告)日：2014-03-18
申请号：US12358073
申请日：2009-01-22
申请人： Todd K. Whitehurst , Kristen N. Jaax , Rafael Carbunaru , Greg Baldwin , Brett Schleicher , Andrew DiGiore , Roger Hastings
发明人： Todd K. Whitehurst , Kristen N. Jaax , Rafael Carbunaru , Greg Baldwin , Brett Schleicher , Andrew DiGiore , Roger Hastings
IPC分类号： A61N1/05
CPC分类号： A61N1/36007 , A61N1/0551 , A61N1/36071 , A61N1/37205 , A61N1/37252
摘要： Methods and systems of treating a patient with pancreatitis pain include providing a stimulator, configuring one or more stimulation parameters to treat pancreatitis pain, programming the stimulator with the one or more stimulation parameters, generating a stimulus configured to treat pancreatitis pain with the stimulator in accordance with the one or more stimulation parameters, and applying the stimulus with the stimulator to one or more stimulation sites in accordance with the one or more stimulation parameters.
摘要翻译： 治疗患有胰腺炎疼痛的患者的方法和系统包括提供刺激器，配置一个或多个刺激参数以治疗胰腺炎疼痛，用所述一个或多个刺激参数编程所述刺激器，产生被配置为按照所述刺激器治疗胰腺炎疼痛的刺激 与所述一个或多个刺激参数相关联，并且根据所述一个或多个刺激参数将刺激器刺激施加到一个或多个刺激位点。
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10.发明申请METHODS AND SYSTEMS OF TREATING PANCREATITIS PAIN CAUSED BY SPHINCTER OF ODDI DYSFUNCTION 有权治疗由ODDI功能障碍引起的胰腺疼痛的方法与系统公开(公告)号：US20090192557A1
公开(公告)日：2009-07-30
申请号：US12358002
申请日：2009-01-22
申请人： Todd K. Whitehurst , Rafael Carbunaru , Kristen N. Jaax , Andrew DiGiore , Brett Schleicher , Greg Baldwin , Roger Hastings
发明人： Todd K. Whitehurst , Rafael Carbunaru , Kristen N. Jaax , Andrew DiGiore , Brett Schleicher , Greg Baldwin , Roger Hastings
CPC分类号： A61N1/36007 , A61N1/36071 , A61N1/37205 , A61N1/37252
摘要： Methods and systems of treating a patient with pancreatitis pain include providing a stimulator, configuring one or more stimulation parameters to control sphincter of Oddi function, programming the stimulator with the one or more stimulation parameters, generating a stimulus configured to control sphincter of Oddi function with the stimulator in accordance with the one or more stimulation parameters, and applying the stimulus with the stimulator to one or more stimulation sites in accordance with the one or more stimulation parameters.
摘要翻译： 用于治疗患有胰腺炎疼痛的患者的方法和系统包括提供刺激器，配置一个或多个刺激参数以控制Oddi功能的括约肌，用所述一个或多个刺激参数编程所述刺激器，产生被配置为控制Oddi功能的括约肌的刺激， 所述刺激器根据所述一个或多个刺激参数，以及根据所述一个或多个刺激参数将刺激器刺激施加到一个或多个刺激部位。
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