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公开(公告)号：US08475449B2
公开(公告)日：2013-07-02
申请号：US12332236
申请日：2008-12-10
申请人： Randell L. Werneth , Ricardo D. Roman , Christopher G. Kunis , Alexander J. Asconeguy , Sadaf Soleymani , Martin Chambers , Hakan Oral , Fred Morady , Jerald L. Cox , Guillermo W. Moratorio , Samuel Fu , J. Christopher Flaherty , Nenita Trinidad
发明人： Randell L. Werneth , Ricardo D. Roman , Christopher G. Kunis , Alexander J. Asconeguy , Sadaf Soleymani , Jeffrey Trinidad , Martin Chambers , Hakan Oral , Fred Morady , Jerald L. Cox , Guillermo W. Moratorio , Samuel Fu , J. Christopher Flaherty
IPC分类号： A61B18/18
CPC分类号： A61B18/1492 , A61B17/00234 , A61B18/18 , A61B2017/00044 , A61B2017/003 , A61B2018/00184 , A61B2018/00351 , A61B2018/00357 , A61B2018/00577 , A61B2018/00839
摘要： Devices, systems and methods are disclosed for the ablation of tissue. A steerable ablation catheter can include one or more ablation elements at its distal end and one or more ablation elements fixedly attached to its shaft. The distal end of the ablation catheter can be deflected to assume a number of different deflection geometries in at least one direction along the shaft. One feature of the ablation catheter is that its shaft can comprise materials of differing durometers or stiffnesses attached together at a joint. Methods associated with use of the ablation catheter are also covered.
摘要翻译： 公开了用于组织消融的装置，系统和方法。 可引导的消融导管可包括其远端处的一个或多个消融元件和固定地附接到其轴的一个或多个消融元件。 消融导管的远端可以沿着轴在至少一个方向上被偏转以呈现多个不同的偏转几何形状。 消融导管的一个特征是其轴可以包括在接头处附接在一起的不同硬度的刚度的材料。 还涉及与使用消融导管相关的方法。
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公开(公告)号：US20090149848A1
公开(公告)日：2009-06-11
申请号：US12332236
申请日：2008-12-10
申请人： Randell L. Werneth , Ricardo D. Roman , Christopher G. Kunis , Alexander J. Asconeguy , Sadaf Soleymani , Jeffrey Trinidad , Nenita Trinidad , Martin Chambers , Hakan Oral , Fred Morady , Jerald L. Cox , Guillermo W. Moratorio , Samuel Fu , J. Christopher Flaherty
发明人： Randell L. Werneth , Ricardo D. Roman , Christopher G. Kunis , Alexander J. Asconeguy , Sadaf Soleymani , Jeffrey Trinidad , Nenita Trinidad , Martin Chambers , Hakan Oral , Fred Morady , Jerald L. Cox , Guillermo W. Moratorio , Samuel Fu , J. Christopher Flaherty
CPC分类号： A61B18/1492 , A61B17/00234 , A61B18/18 , A61B2017/00044 , A61B2017/003 , A61B2018/00184 , A61B2018/00351 , A61B2018/00357 , A61B2018/00577 , A61B2018/00839
摘要： Devices, systems and methods are disclosed for the ablation of tissue. A steerable ablation catheter can include one or more ablation elements at its distal end and one or more ablation elements fixedly attached to its shaft. The distal end of the ablation catheter can be deflected to assume a number of different deflection geometries in at least one direction along the shaft. One feature of the ablation catheter is that its shaft can comprise materials of differing durometers or stiffnesses attached together at a joint. Methods associated with use of the ablation catheter are also covered.
摘要翻译： 公开了用于组织消融的装置，系统和方法。 可引导的消融导管可包括其远端处的一个或多个消融元件和固定地附接到其轴的一个或多个消融元件。 消融导管的远端可以沿着轴在至少一个方向上被偏转以呈现多个不同的偏转几何形状。 消融导管的一个特征是其轴可以包括在接头处附接在一起的不同硬度的刚度的材料。 还涉及与使用消融导管相关的方法。
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3.发明授权公开(公告)号：US08641704B2
公开(公告)日：2014-02-04
申请号：US12116753
申请日：2008-05-07
IPC分类号： A61B18/14
CPC分类号： A61B18/1492 , A61B18/1206 , A61B2018/00214 , A61B2018/00375 , A61B2018/1407 , A61B2018/1467 , A61B2018/1475
摘要： An ablation therapy system and systematic method is provided for treating continuous atrial fibrillation. The therapy system includes a Multi-Channel RF Ablation Generator, an ECG interface, an assembly of at least three ablation catheters, and an ECG interface operably coupling and interfacing the catheters to both an ECG unit and the RF Ablation Generator. The systematic method includes transseptally accessing the Left Atrium (LA) through the septum of the patient's heart, and performing an endocardial pulmonary vein ablation procedure on the pulmonary vein ostial tissue surrounding one or more pulmonary veins in a manner treating aberrant conductive pathways therethrough. After performing the pulmonary vein ablation, the method further includes performing an endocardial atrial septum ablation procedure on the septal tissue in a manner treating aberrant conductive pathways therethrough.
摘要翻译： 提供消融治疗系统和系统方法治疗连续性房颤。 治疗系统包括多通道RF消融发生器，ECG接口，至少三个消融导管的组件，以及将导管可操作地耦合和接口到ECG单元和RF消融发生器的ECG接口。 系统方法包括通过患者心脏的隔膜经皮穿透左心房（LA），并以围绕一个或多个肺静脉的肺静脉口腔组织以以治疗异常导电通路的方式进行心内膜肺静脉消融手术。 在进行肺静脉消融后，该方法还包括以处理通过其中的异常导电通路的方式对隔膜组织进行心内膜心房隔膜消融手术。
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4.发明申请公开(公告)号：US20080281312A1
公开(公告)日：2008-11-13
申请号：US12116753
申请日：2008-05-07
IPC分类号： A61B18/18
CPC分类号： A61B18/1492 , A61B18/1206 , A61B2018/00214 , A61B2018/00375 , A61B2018/1407 , A61B2018/1467 , A61B2018/1475
摘要： An ablation therapy system and systematic method is provided for treating continuous atrial fibrillation. The therapy system includes a Multi-Channel RF Ablation Generator, an ECG interface, an assembly of at least three ablation catheters, and an ECG interface operably coupling and interfacing the catheters to both an ECG unit and the RF Ablation Generator. The systematic method includes transseptally accessing the Left Atrium (LA) through the septum of the patient's heart, and performing an endocardial pulmonary vein ablation procedure on the pulmonary vein ostial tissue surrounding one or more pulmonary veins in a manner treating aberrant conductive pathways therethrough. After performing the pulmonary vein ablation, the method further includes performing an endocardial atrial septum ablation procedure on the septal tissue in a manner treating aberrant conductive pathways therethrough.
摘要翻译： 提供消融治疗系统和系统方法治疗连续性房颤。 治疗系统包括多通道RF消融发生器，ECG接口，至少三个消融导管的组件，以及将导管可操作地耦合和接口到ECG单元和RF消融发生器的ECG接口。 系统方法包括通过患者心脏的隔膜经皮穿透左心房（LA），并以围绕一个或多个肺静脉的肺静脉口腔组织以以治疗异常导电通路的方式进行心内膜肺静脉消融手术。 在进行肺静脉消融后，该方法还包括以处理通过其中的异常导电通路的方式对隔膜组织进行心内膜心房隔膜消融手术。
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公开(公告)号：US08657814B2
公开(公告)日：2014-02-25
申请号：US11438678
申请日：2006-05-22
申请人： Randell L. Werneth , J. Christopher Flaherty , Hakan Oral , Fred Morady , Ricardo David Roman , Marshall L. Sherman
发明人： Randell L. Werneth , J. Christopher Flaherty , Hakan Oral , Fred Morady , Ricardo David Roman , Marshall L. Sherman
IPC分类号： A61B18/18
CPC分类号： A61B18/1492 , A61B5/0422 , A61B5/7217 , A61B5/742 , A61B5/7435 , A61B5/7445 , A61B18/02 , A61B90/37 , A61B2018/0016 , A61B2018/00214 , A61B2018/00351 , A61B2018/00577 , A61B2018/00642 , A61B2018/00654 , A61B2018/00702 , A61B2018/00779 , A61B2018/00791 , A61B2018/00797 , A61B2018/00821 , A61B2018/00839 , A61B2018/00982 , A61B2018/124
摘要： Devices, systems and methods are disclosed for the ablation of tissue. Embodiments include an ablation catheter that has an array of ablation elements attached to a deployable carrier assembly. The carrier assembly can be constrained within the lumen of a catheter, and deployed to take on an expanded condition. The carrier assembly includes multiple electrodes that are configured to ablate tissue at low power. Systems include an interface unit with a visual display that provides a visual representation of the geometry of the ablation elements and/or provides selection means for selecting an icon provided on the display.
摘要翻译： 公开了用于组织消融的装置，系统和方法。 实施例包括消融导管，其具有附接到可展开的载体组件的消融元件阵列。 载体组件可以被限制在导管的内腔中，并且被部署以展开扩张状态。 载体组件包括被配置成以低功率消融组织的多个电极。 系统包括具有视觉显示器的接口单元，其提供消融元件的几何形状的可视表示和/或提供用于选择在显示器上提供的图标的选择装置。
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6.发明授权Atrial ablation catheter adapted for treatment of septal wall arrhythmogenic foci and method of use 有权适用于治疗隔膜致心律失常灶的心房消融导管及其使用方法公开(公告)号：US07468062B2
公开(公告)日：2008-12-23
申请号：US10997713
申请日：2004-11-24
IPC分类号： A61B18/18
CPC分类号： A61B18/1492 , A61B2018/0016 , A61B2018/00214 , A61B2018/00267 , A61B2018/00351 , A61B2018/1475
摘要： An atrial ablation catheter with an electrode array particularly adapted to locate and ablate foci of arrhythmia which are required for sustained atrial fibrillation is provided. The array is easily deployed and retracted from the catheter, and presents a proximally oriented electrode array that can be pulled against the septal wall of the left atrium to engage the septal wall.
摘要翻译： 提供了具有特别适于定位和消融持续性房颤所需的心律失常灶的电极阵列的心房消融导管。 该阵列容易地从导管展开和缩回，并且呈现近端定向的电极阵列，其可以被拉到左心房的隔壁以接合隔膜。
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7.发明授权Atrial ablation catheter adapted for treatment of septal wall arrhythmogenic foci and method of use 有权适用于治疗隔膜致心律失常灶的心房消融导管及其使用方法公开(公告)号：US09005194B2
公开(公告)日：2015-04-14
申请号：US12176115
申请日：2008-07-18
CPC分类号： A61B18/1492 , A61B2018/0016 , A61B2018/00214 , A61B2018/00267 , A61B2018/00351 , A61B2018/1475
摘要： An atrial ablation catheter with an electrode array particularly adapted to locate and ablate foci of arrhythmia which are required for sustained atrial fibrillation is provided. The array is easily deployed and retracted from the catheter, and presents a proximally oriented electrode array that can be pulled against the septal wall of the left atrium to engage the septal wall.
摘要翻译： 提供了具有特别适于定位和消融持续性房颤所需的心律失常灶的电极阵列的心房消融导管。 该阵列容易地从导管展开和缩回，并且呈现近端定向的电极阵列，其可以被拉到左心房的隔壁以接合隔膜。
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8.发明申请ATRIAL ABLATION CATHETER ADAPTED FOR TREATMENT OF SEPTAL WALL ARRHYTHMOGENIC FOCI AND METHOD OF USE 有权适用于治疗宫颈癌发生骨髓的ATRIAL ABLATION CATHETER及其使用方法公开(公告)号：US20080275443A1
公开(公告)日：2008-11-06
申请号：US12176115
申请日：2008-07-18
IPC分类号： A61B18/14
CPC分类号： A61B18/1492 , A61B2018/0016 , A61B2018/00214 , A61B2018/00267 , A61B2018/00351 , A61B2018/1475
摘要： An atrial ablation catheter with an electrode array particularly adapted to locate and ablate foci of arrhythmia which are required for sustained atrial fibrillation is provided. The array is easily deployed and retracted from the catheter, and presents a proximally oriented electrode array that can be pulled against the septal wall of the left atrium to engage the septal wall.
摘要翻译： 提供了具有特别适于定位和消融持续性房颤所需的心律失常灶的电极阵列的心房消融导管。 该阵列容易地从导管展开和缩回，并且呈现近端定向的电极阵列，其可以被拉到左心房的隔壁以接合隔膜。
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9.发明申请Non-Contact Infrared Fiber-Optic Device for Monitoring Esophageal Temperature to Prevent Thermal Injury During Radiofrequency Catheter Ablation or Cryoablation 有权用于监测食管温度以防止射频导管消融或冷冻消融期间的热损伤的非接触式红外光纤装置公开(公告)号：US20110028788A1
公开(公告)日：2011-02-03
申请号：US12934008
申请日：2009-03-24
申请人： Hakan Oral , Fred Morady
发明人： Hakan Oral , Fred Morady
IPC分类号： A61B1/06
CPC分类号： A61B5/01 , A61B1/00096 , A61B1/273 , A61B5/015 , A61B5/412 , A61B5/7278 , A61B18/0218 , A61B18/12 , A61B18/1206 , A61B18/18 , A61B2017/00057 , A61B2017/00061 , A61B2017/00084 , A61B2018/00011 , A61B2018/00488 , A61B2018/0212 , A61B2562/0271 , G01J5/0022 , G01J5/0025 , G01J5/02 , G01J5/0215 , G01J5/04 , G01J5/047 , G01J5/08 , G01J5/0803 , G01J5/0806 , G01J5/0809 , G01J5/0818 , G01J5/0843 , G01J5/0846 , G01J2005/0081
摘要： An infrared fiber-optic device is able to monitor esophageal temperature during an ablation/cryoablation procedure over a volume of interest to sense whether the temperature is too high or too low. The device may include a plurality of optical fibers each with a wide angle lens collectively disposed circumferentially and longitudinally to cover the volume of interest, as the particular region over which undesirable temperature may not be known beforehand. In other examples, the device may include an embedded array of infrared sensors extending sufficiently to encompass a volume of interest. The device may be used as part of a feedback control to regulate and stop operation of the ablation/cryoablation procedure to prevent vessel damage.
摘要翻译： 红外光纤装置能够在消融/冷冻消融手术过程中监视食管温度，感兴趣的体积以感测温度是否太高或太低。 该装置可以包括多个光纤，每个光纤具有沿着周向和纵向共同设置的广角透镜，以覆盖感兴趣的体积，作为预期不知道不期望的温度的特定区域。 在其他示例中，该装置可以包括充分扩展以包含感兴趣体积的红外传感器的嵌入阵列。 该装置可以用作反馈控制的一部分，以调节和停止消融/冷冻消融程序的操作以防止血管损伤。
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公开(公告)号：US20050240176A1
公开(公告)日：2005-10-27
申请号：US11159055
申请日：2005-06-22
申请人： Hakan Oral , Fred Morady
发明人： Hakan Oral , Fred Morady
IPC分类号： A61B18/14
CPC分类号： A61B18/1492 , A61B2018/00214 , A61B2018/1435
摘要： The present invention relates generally to multifunctional catheters for performing ablation procedures, and more particularly to ablation catheters utilized in the treatment of atrial fibrillation and other cardiac disorders. The present invention eliminates many of the problems associated with previous ablation catheters by providing an ablation treatment not dependent upon continuous lesions.
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