公开(公告)号：US20070255094A1

公开(公告)日：2007-11-01

申请号：US11375380

申请日：2006-03-13

申请人： Randolf Oepen ,  Travis Yribarren ,  Anton Clifford

发明人： Randolf Oepen ,  Travis Yribarren ,  Anton Clifford

IPC分类号： A61B1/00

CPC分类号： A61F2/915 ,  A61F2/91 ,  A61F2002/3008 ,  A61F2002/30329 ,  A61F2002/91508 ,  A61F2002/91525 ,  A61F2002/91533 ,  A61F2002/91558 ,  A61F2220/0025 ,  A61F2230/0054 ,  A61F2240/001 ,  A61F2250/0068 ,  A61F2250/0098

摘要： An endoprosthesis for delivery in a body lumen can be configured to inhibit crack formation and/or crack propagation, and/or fatigue-induced catastrophic failure by the use of holes extending through an endoprosthetic element. As such, the endoprosthesis can include at least one strut element having a strut width and a strut thickness, the strut thickness being defined by a first side opposite a second side. The element can be characterized by having a plurality of holes extending from the first side to the second side. The plurality of holes can be arranged in an amount, distribution, and/or pattern so as to inhibit crack propagation across the strut length or strut width.

摘要翻译： 用于在体腔内递送的内用假体可以被配置为通过使用延伸穿过假体内元件的孔来抑制裂缝形成和/或裂纹扩展，和/或疲劳引起的灾难性故障。 因此，内假体可以包括至少一个支柱元件，支柱宽度和支柱厚度，支柱厚度由与第二侧相对的第一侧限定。 元件的特征在于具有从第一侧延伸到第二侧的多个孔。 可以以数量，分布和/或图案布置多个孔，以便抑制穿过支柱长度或支柱宽度的裂纹扩展。

公开(公告)号：US20060235505A1

公开(公告)日：2006-10-19

申请号：US11375381

申请日：2006-03-13

申请人： Randolf Oepen ,  Anton Clifford ,  Travis Yribarren

发明人： Randolf Oepen ,  Anton Clifford ,  Travis Yribarren

IPC分类号： A61F2/06

CPC分类号： A61F2/91 ,  A61F2/0077 ,  A61F2/90 ,  A61F2/915 ,  A61F2002/3008 ,  A61F2002/30329 ,  A61F2002/828 ,  A61F2002/91508 ,  A61F2002/91533 ,  A61F2002/9155 ,  A61F2002/91558 ,  A61F2002/91583 ,  A61F2210/0076 ,  A61F2220/0025 ,  A61F2230/0054 ,  A61F2240/001 ,  A61F2250/0068 ,  A61F2250/0098

摘要： A crack-resistant endoprosthesis for delivery in a body lumen can be comprised of a multilayered material. The multilayered material can include at least two layers having a boundary layer therebetween. The boundary layer is configured to inhibit cracks from propagating from a first layer-to a second layer. The different layers can be comprised of the same materials or different materials. It can be preferred that the multilayered material have layers that are comprised of resiliently-flexible materials, shape memory materials, and/or radiopaque materials.

摘要翻译： 用于在体腔中输送的抗裂内固定物可以由多层材料构成。 多层材料可以包括其间具有边界层的至少两层。 边界层被配置为抑制裂纹从第一层传播到第二层。 不同的层可以由相同的材料或不同的材料组成。 可以优选的是，多层材料具有由弹性柔性材料，形状记忆材料和/或不透射线材料构成的层。

公开(公告)号：US20070016240A1

公开(公告)日：2007-01-18

申请号：US11455382

申请日：2006-06-19

申请人： Boris Warnack ,  Judith Hartwig ,  Silke Pschibl ,  Travis Yribarren ,  Randolf Oepen ,  Thomas Rieth ,  Lorcan Coffey ,  Arik Zucker

发明人： Boris Warnack ,  Judith Hartwig ,  Silke Pschibl ,  Travis Yribarren ,  Randolf Oepen ,  Thomas Rieth ,  Lorcan Coffey ,  Arik Zucker

IPC分类号： A61M29/00

CPC分类号： A61M25/104 ,  A61M25/1034 ,  A61M25/1038 ,  A61M2025/1004 ,  A61M2025/1031 ,  A61M2025/1086 ,  A61M2025/1093 ,  B23K2103/42 ,  B23K2103/50 ,  B29C59/165 ,  B29C2791/009 ,  B29L2031/7542 ,  Y10T156/1062

摘要： A dilatation balloon is fabricated according to a process that forms cavities and indentations in the balloon and/or catheter sections. A length of tubing is axially elongated and radially expanded in a form to provide the requisite biaxial orientation and strength. Then, an excimer laser or another type of laser or mechanical material removal tool is used to remove the polymeric material, virtually without thermal effects. Cavities in the sleeve sections of the balloon are defined and if desired, indentations in the cone sections are defined. Material removal, particularly near the balloon sleeves enables a thinner, more flexible bonding area between the catheter shaft and the balloon. Further, the indentations along the cone sections enables tighter wrapping of the balloon for a reduced delivery profile. Rigidity near the sleeves is reduced for better maneuverability of the catheter in tortuous passageways.

摘要翻译： 根据在球囊和/或导管部分中形成空腔和凹陷的方法制造扩张球囊。 一段长度的管材是轴向伸长的并以一种形式径向扩张以提供必要的双轴取向和强度。 然后，使用准分子激光器或其他类型的激光或机械材料去除工具来去除聚合物材料，实际上没有热效应。 气囊的套筒部分中的腔被限定，并且如果需要，限定锥形部分中的凹陷。 材料去除，特别是靠近气球套筒，能够在导管轴和球囊之间形成更薄，更灵活的粘结区域。 此外，沿着锥形部分的凹陷使得气囊能够更紧密地包裹以减少输送轮廓。 袖子附近的刚性减少，导致导管在弯曲通道中的更好的机动性。

公开(公告)号：US20060287703A1

公开(公告)日：2006-12-21

申请号：US11509346

申请日：2006-08-23

申请人： Randolf Oepen ,  Thomas Rieth ,  Lorcan Coffey ,  Arik Zucker ,  Travis Yribarren

发明人： Randolf Oepen ,  Thomas Rieth ,  Lorcan Coffey ,  Arik Zucker ,  Travis Yribarren

IPC分类号： A61F2/06

CPC分类号： A61F2/958 ,  A61F2/856 ,  A61F2/954 ,  A61M2025/09125 ,  A61M2025/1015

摘要： A stent delivery system is disclosed for delivering and deploying a radially expandable stent at a strategic orientation and location in a body vessel. The delivery system includes an elongated flexible tubular shaft sized suitably for insertion into the body vessel. A stent deployment assembly includes a distal transition portion supporting a dilator device adapted for radial expansion about a longitudinal axis of the deployment assembly from a non-expanded condition to a radially expanded condition. The dilator device is configured to support the stent thereon in the non-expanded condition and in predetermined orientation relative the deployment assembly. A rotational clutch assembly rotatably mounts the transition portion to a distal portion of the tubular shaft such that the deployment assembly is substantially torsionally isolated from the tubular shaft, about a longitudinal axis of the clutch assembly. This enables the stent deployment assembly to rotate substantially independently of the tubular shaft for strategic orientation of the dilator device during advancement through the body vessel.

摘要翻译： 公开了用于在体内容器中的战略取向和位置处递送和展开径向可扩张的支架的支架输送系统。 递送系统包括适于插入身体容器中的细长柔性管状轴。 支架展开组件包括支撑扩张器装置的远侧过渡部分，所述扩张器装置适于围绕展开组件的纵向轴线从非扩张状态到径向膨胀状态的径向膨胀。 扩张器装置构造成在非扩张状态下以相对于展开组件的预定取向支撑其上的支架。 旋转离合器组件将过渡部分可旋转地安装到管状轴的远侧部分，使得展开组件围绕离合器组件的纵向轴线与管状轴基本上扭转隔离。 这使得支架展开组件能够基本上独立于管状轴线旋转，以便在穿过身体血管的进展期间扩张器装置的战略取向。

公开(公告)号：US20070288081A1

公开(公告)日：2007-12-13

申请号：US11747145

申请日：2007-05-10

申请人： Randolf Oepen ,  Arik Zucker ,  Travis Yribarren ,  Thomas Rieth ,  Lorcan Coffey

发明人： Randolf Oepen ,  Arik Zucker ,  Travis Yribarren ,  Thomas Rieth ,  Lorcan Coffey

IPC分类号： A61F2/06

CPC分类号： A61F2/958 ,  A61F2002/821 ,  A61F2002/9586

摘要： Disclosed are stent delivery apparatus and methods for moving a balloon catheter carrying a stent through a body vessel without the stent slipping from the balloon are provided. In general, the stent delivery system includes a stent stopper that impedes the stent from slipping from the balloon. The stent stopper is sized to serve as a barrier to the stent as it is carried on the balloon. In a specific embodiment, the stent stopper is formed from a material that encircles the proximal end of the balloon and abuts the proximal end of the stent. The stent stopper material expands with expansion of the balloon and collapses with deflation of the balloon. In some embodiments, the stent stopper material has a thickness that is about equal to or greater than the thickness of the stent so as to form a barrier against the stent and impede the stent from slipping off the proximal end of the balloon.

摘要翻译： 公开了用于移动携带支架的球囊导管通过身体容器而没有支架从气囊滑落的支架输送装置和方法。 通常，支架输送系统包括阻止支架从气囊滑落的支架塞子。 支架止动器的尺寸被设计成当支架承载在气囊上时用作支架的屏障。 在具体实施例中，支架止动器由围绕球囊的近端并邻接支架的近端的材料形成。 支架塞材料随气囊膨胀而膨胀，并伴随气囊的放气而塌陷。 在一些实施例中，支架止动器材料具有大约等于或大于支架厚度的厚度，以便形成抵靠支架的阻挡层并阻止支架从气囊的近端滑落。

公开(公告)号：US20070021685A1

公开(公告)日：2007-01-25

申请号：US11429424

申请日：2006-05-04

申请人： Randolf Oepen ,  Travis Yribarren ,  Thomas Rieth ,  Lorcan Coffey ,  Arik Zucker

发明人： Randolf Oepen ,  Travis Yribarren ,  Thomas Rieth ,  Lorcan Coffey ,  Arik Zucker

IPC分类号： A61M25/00

CPC分类号： A61M25/09 ,  A61M2025/09125 ,  A61M2025/09175 ,  A61M2025/09183

摘要： A guidewire apparatus for a medical device that includes an expandable guidewire section that can be locked in an expanded state. In one use, the expandable section can be temporarily locked to a working element of a medical device to facilitate the transmission of torque from the guidewire to the medical device. Hence, this configuration may be utilized to aid in orientation of the working element with a vessel side branch by providing the user with the ability to apply a rotational force to the distal end of the stent delivery system. Another use includes docking the expandable section near an opening into a guidewire lumen at the catheter tip. This configuration is particularly useful in forming a smooth transition between the guidewire and the catheter tip to reduce the phenomenon of fish-mouthing.

摘要翻译： 一种用于医疗装置的导丝装置，其包括能够被锁定在展开状态的可扩张导丝部分。 在一种用途中，可扩张部分可以临时锁定到医疗装置的工作元件，以便于将扭矩从导丝传递到医疗装置。 因此，这种构造可以用于通过向使用者提供向支架输送系统的远端施加旋转力的能力来帮助工作元件与血管侧分支的取向。 另一种用途包括将开口附近的可扩张部分对接在导管尖端处的导丝管腔中。 这种构造在形成导丝和导管尖端之间的平滑过渡以减少鱼嘴的现象特别有用。

公开(公告)号：US20060282154A1

公开(公告)日：2006-12-14

申请号：US11441388

申请日：2006-05-24

申请人： Randolf Oepen ,  Thomas Rieth ,  Lorcan Coffey ,  Arik Zucker ,  Travis Yribarren

发明人： Randolf Oepen ,  Thomas Rieth ,  Lorcan Coffey ,  Arik Zucker ,  Travis Yribarren

IPC分类号： A61F2/06

CPC分类号： A61F2/958 ,  A61F2/856 ,  A61F2/954 ,  A61M2025/09125 ,  A61M2025/1015

摘要： A stent delivery system is disclosed for delivering and deploying a radially expandable stent at a strategic orientation and location in a body vessel. The delivery system includes an elongated flexible tubular shaft sized suitably for insertion into the body vessel. A stent deployment assembly includes a distal transition portion supporting a dilator device adapted for radial expansion about a longitudinal axis of the deployment assembly from a non-expanded condition to a radially expanded condition. The dilator device is configured to support the stent thereon in the non-expanded condition and in predetermined orientation relative the deployment assembly. A rotational clutch assembly rotatably mounts the transition portion to a distal portion of the tubular shaft such that the deployment assembly is substantially torsionally isolated from the tubular shaft, about a longitudinal axis of the clutch assembly. This enables the stent deployment assembly to rotate substantially independently of the tubular shaft for strategic orientation of the dilator device during advancement through the body vessel.

公开(公告)号：US20070021771A1

公开(公告)日：2007-01-25

申请号：US11439592

申请日：2006-05-23

申请人： Randolf Oepen ,  Axel Grandt ,  Andrew Jeffrey ,  Guenter Lorenz

发明人： Randolf Oepen ,  Axel Grandt ,  Andrew Jeffrey ,  Guenter Lorenz

IPC分类号： A61M29/00

CPC分类号： A61M25/10 ,  A61M25/0021 ,  A61M25/0029 ,  A61M25/0032 ,  A61M25/0043 ,  A61M29/00 ,  A61M2025/0063 ,  A61M2025/0183 ,  A61M2025/1056

摘要： The invention includes a catheter having an elongate main body having a proximal section and a distal section. The elongate main body further includes a plurality of stiffening members disposed along the length of the elongate main body. The plurality of stiffening members includes a first stiffening member and a second stiffening member. The catheter can also include a balloon formed from a tubular member having a recess defined in a portion of its surface. A tapered or thinned balloon is formed from a process by which material is removed from a tubular member prior to formation of the balloon.

摘要翻译： 本发明包括具有细长主体的导管，该主体具有近端部分和远端部分。 细长主体还包括沿着细长主体的长度设置的多个加强构件。 多个加强构件包括第一加强构件和第二加强构件。 导管还可以包括由管状构件形成的气囊，所述管状构件具有限定在其表面的一部分中的凹部。 从形成气囊之前从管状构件移除材料的过程形成锥形或变薄的球囊。

公开(公告)号：US20060184232A1

公开(公告)日：2006-08-17

申请号：US11404450

申请日：2006-04-14

申请人： Marc Gianotti ,  Kenneth Michlitsch ,  Suk-Woo Ha ,  Randolf Oepen ,  Gerd Seibold

发明人： Marc Gianotti ,  Kenneth Michlitsch ,  Suk-Woo Ha ,  Randolf Oepen ,  Gerd Seibold

IPC分类号： A61F2/06

CPC分类号： A61F2/91 ,  A61F2/915 ,  A61F2002/91508 ,  A61F2002/91533 ,  A61F2002/91558 ,  A61F2230/0054

摘要： The present invention provides a stent comprising a tubular flexible body having a wall with a web structure that is expandable from a contracted delivery configuration to deployed configuration. The web structure comprises a plurality of neighboring, interconnected, web patterns, each web pattern composed of adjoining webs. Each adjoining web comprises a central section interposed between two lateral sections, forming concave or convex configurations. Embodiments of the present invention comprising curvature for tracking tortuous anatomy and reducing localized restoring forces are provided. Methods of using stents in accordance with the present invention are also provided.

摘要翻译： 本发明提供了一种支架，其包括管状柔性体，其具有壁，所述壁具有可从收缩输送构型扩展到展开构造的腹板结构。 幅材结构包括多个相邻的，互连的幅材图案，每个幅材图案由相邻的幅材组成。 每个邻接的腹板包括插入在两个横向部分之间的中心部分，形成凹形或凸形构造。 提供了包括用于跟踪曲折解剖结构并减少局部恢复力的曲率的本发明的实施例。 还提供了使用根据本发明的支架的方法。

公开(公告)号：US20050080483A1

公开(公告)日：2005-04-14

申请号：US10500188

申请日：2002-12-20

申请人： Jan Solem ,  Per Kimblad ,  Randolf Oepen ,  Bodo Quint ,  Gerd Seibold ,  Kenneth Michlitsch ,  Suk-Woo Ha ,  Karl-Ludwig Eckert ,  Ib Joergensen ,  Stevan Nielsen

发明人： Jan Solem ,  Per Kimblad ,  Randolf Oepen ,  Bodo Quint ,  Gerd Seibold ,  Kenneth Michlitsch ,  Suk-Woo Ha ,  Karl-Ludwig Eckert ,  Ib Joergensen ,  Stevan Nielsen

IPC分类号： A61F2/02 ,  A61F2/04 ,  A61F2/07 ,  A61F2/24 ,  A61F2/26 ,  A61F2/82 ,  A61F2/848

CPC分类号： A61F2/2451 ,  A61F2/07 ,  A61F2/2481 ,  A61F2/26 ,  A61F2002/043 ,  A61F2002/072 ,  A61F2002/826 ,  A61F2002/828 ,  A61F2002/8483 ,  A61F2210/0004

摘要： A device for reshaping a cardiac valve (26), which is elongate and has such dimensions as to be insertable into a cardiac vessel (24). The device has two states, in a first state (K) of which the device has a shape that is adaptable to the shape of the vessel (24), and to the second state (k′) of which the device is transferable from said first state (K). Further, the device comprises a fixing means (22,23;22a,23a) for fixing the ends of the device within the vessel (24), when the device is first positioned therein, a shape-changing member (20;20a) for transferring the device to the second state (K′) by reshaping it, and a delay means (21;21a) for delaying said reshaping until the fixing of the ends of the device has been reinforced by keeping said device in said first state (K) until the delay means (21;21a) is resorbed.

摘要翻译： 一种用于整形心脏瓣膜（26）的装置，其是细长的并且具有可插入心脏容器（24）的尺寸。 该装置具有两种状态，其处于第一状态（K），其装置具有适应于容器（24）的形状的形状，以及第二状态（k'），其中装置可从所述第二状态 第一个状态（K）。 此外，该装置包括固定装置（22,23; 22a，23a），用于当装置首先定位在容器（24）内时将装置的端部固定，形状改变构件（20; 20a） 通过重新形成将装置转移到第二状态（K'），以及用于延迟所述重新成形的延迟装置（21; 21a），直到通过将所述装置保持在所述第一状态（K ），直到延迟装置（21; 21a）被再吸收。