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公开(公告)号：US20060287702A1
公开(公告)日：2006-12-21
申请号：US11461581
申请日：2006-08-01
Applicant: Rangarajan Sundar
Inventor： Rangarajan Sundar
CPC classification number: B05D1/002 , A61F2250/0067 , A61L31/10 , B05C3/04 , B05C3/10 , B05C11/08 , B05D1/18 , B05D7/50
Abstract: The invention provides a stent delivery system and a stent device. The stent delivery system includes a catheter, a balloon operably attached to the catheter, and a stent disposed on the balloon. The stent includes at least one coating applied by dipping a portion of the stent into a coating liquid while simultaneously rotating the stent. The stent device includes a body and at least one coating rotationally applied to a portion of the body, while the body is at least partially immersed in a coating liquid.
Abstract translation: 本发明提供一种支架输送系统和支架装置。 支架输送系统包括导管，可操作地附接到导管的气囊和设置在气囊上的支架。 支架包括通过将支架的一部分浸入涂覆液体同时旋转支架而施加的至少一个涂层。 支架装置包括主体和至少一个旋转地施加到主体的一部分的涂层，同时主体至少部分地浸入涂覆液体中。
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公开(公告)号：US06979348B2
公开(公告)日：2005-12-27
申请号：US10454652
申请日：2003-06-04
Applicant: Rangarajan Sundar
Inventor： Rangarajan Sundar
CPC classification number: A61F2/82 , A61F2/91 , A61F2/915 , A61F2002/91541 , A61F2230/0054 , A61F2240/001 , A61F2250/0067 , B05C3/09 , B05C9/14 , B05C11/1039 , Y10S623/901
Abstract: The present invention provides a method of forming a drug-polymer coated stent. A polymeric coating is applied onto at least a portion of a stent framework and dried. A jet of heated gas is directed towards excess coating portions of the dried polymeric coating. The excess coating portions, which extend into apertures of the stent framework, are removed from the apertures of the stent framework by reflowing the polymeric coating with the directed jet of heated gas. A drug-polymer coated stent with a reflowed drug-polymer coating and a system for treating a vascular condition are also disclosed.
Abstract translation: 本发明提供形成药物聚合物涂覆的支架的方法。 将聚合物涂层施加到支架框架的至少一部分上并干燥。 加热气体射流被引导到干燥的聚合物涂层的多余涂层部分。 通过用引导的加热气体射流喷射聚合物涂层，延伸到支架框架的孔中的多余涂层部分从支架框架的孔中移除。 还公开了具有回流药物 - 聚合物涂层的药物聚合物涂覆的支架和用于治疗血管病症的系统。
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公开(公告)号：US07001421B2
公开(公告)日：2006-02-21
申请号：US10376860
申请日：2003-02-28
Applicant: Peiwen Cheng , Rangarajan Sundar , Kaushik A. Patel , Kishore Udipi
Inventor： Peiwen Cheng , Rangarajan Sundar , Kaushik A. Patel , Kishore Udipi
IPC: A61F2/06
CPC classification number: A61L31/10 , A61F2250/0067
Abstract: The present invention provides a system for treating a vascular condition, which includes a catheter; a stent coupled to the catheter, the stent including a stent framework; a phenoxy primer coating operably disposed on the stent framework; and a drug-polymer coating disposed on the phenoxy primer coating. The present invention also provides a drug-coated stent and a method of manufacturing a drug-coated stent.
Abstract translation: 本发明提供一种治疗血管状态的系统，其包括导管; 支架，其联接到所述导管，所述支架包括支架框架; 可操作地设置在支架框架上的苯氧基底漆; 以及设置在苯氧基底漆涂层上的药物 - 聚合物涂层。 本发明还提供了药物包衣的支架和药物包衣支架的制造方法。
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4.发明授权公开(公告)号：US06918929B2
公开(公告)日：2005-07-19
申请号：US10351156
申请日：2003-01-24
Applicant: Kishore Udipi , Peiwen Cheng , Kaushik Patel , Rangarajan Sundar
Inventor： Kishore Udipi , Peiwen Cheng , Kaushik Patel , Rangarajan Sundar
CPC classification number: A61L31/16 , A61K47/6957 , A61L31/10 , A61L2300/606 , C08L51/006 , C08L53/02
Abstract: The present invention provides a system for treating a vascular condition, including a catheter, a stent coupled to the catheter, a drug-polymer coating on the stent including a grafted styrenic block copolymer, and at least one bioactive drug dispersed within the drug-polymer coating.
Abstract translation: 本发明提供了一种用于治疗血管病症的系统，包括导管，与导管联接的支架，支架上的药物聚合物涂层，其包括接枝的苯乙烯嵌段共聚物，以及分散在药物聚合物内的至少一种生物活性药物 涂层。
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5.发明授权Drug-polymer coated stent with blended phenoxy and styrenic block copolymers 有权具有混合苯氧基和苯乙烯嵌段共聚物的药物聚合物涂层支架公开(公告)号：US07144419B2
公开(公告)日：2006-12-05
申请号：US10351136
申请日：2003-01-24
Applicant: Peiwen Cheng , Kishore Udipi , Kaushik Patel , Rangarajan Sundar
Inventor： Peiwen Cheng , Kishore Udipi , Kaushik Patel , Rangarajan Sundar
CPC classification number: A61L31/16 , A61F2250/0067 , A61L31/10 , A61L2300/606 , C08L53/02
Abstract: The present invention provides a system for treating a vascular condition, including a catheter, a stent coupled to the catheter, a drug-polymer coating on the stent including a polymeric blend of a phenoxy polymer and a styrenic block copolymer, and a bioactive drug dispersed within the drug-polymer coating.
Abstract translation: 本发明提供了一种用于治疗血管病症的系统，包括导管，与导管联接的支架，支架上的药物聚合物涂层，其包括苯氧基聚合物和苯乙烯嵌段共聚物的聚合共混物，以及分散的生物活性药物 在药物聚合物涂层内。
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Patent Agency Ranking
公开(公告)号：US20060009834A1
公开(公告)日：2006-01-12
申请号：US11225428
申请日：2005-09-12
Applicant: Rangarajan Sundar
Inventor： Rangarajan Sundar
CPC classification number: A61F2/82 , A61F2/91 , A61F2/915 , A61F2002/91541 , A61F2230/0054 , A61F2240/001 , A61F2250/0067 , B05C3/09 , B05C9/14 , B05C11/1039 , Y10S623/901
Abstract: The present invention provides a method of forming a drug-polymer coated stent. A polymeric coating is applied onto at least a portion of a stent framework and dried. A jet of heated gas is directed towards excess coating portions of the dried polymeric coating. The excess coating portions, which extend into apertures of the stent framework, are removed from the apertures of the stent framework by reflowing the polymeric coating with the directed jet of heated gas. A drug-polymer coated stent with a reflowed drug-polymer coating and a system for treating a vascular condition are also disclosed.
Abstract translation: 本发明提供形成药物聚合物涂覆的支架的方法。 将聚合物涂层施加到支架框架的至少一部分上并干燥。 加热气体射流被引导到干燥的聚合物涂层的多余涂层部分。 通过用引导的加热气体射流喷射聚合物涂层，延伸到支架框架的孔中的多余涂层部分从支架框架的孔中移除。 还公开了具有回流药物 - 聚合物涂层的药物聚合物涂覆的支架和用于治疗血管病症的系统。
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公开(公告)号：US20070110889A1
公开(公告)日：2007-05-17
申请号：US11622269
申请日：2007-01-11
Applicant: Rangarajan Sundar
Inventor： Rangarajan Sundar
CPC classification number: A61F2/82 , A61F2/91 , A61F2/915 , A61F2002/91541 , A61F2230/0054 , A61F2240/001 , A61F2250/0067 , B05C3/09 , B05C9/14 , B05C11/1039 , Y10S623/901
Abstract: A system for forming a drug-polymer coated stent includes means for applying a polymeric coating onto at least a portion of a stent framework, means for drying the applied polymeric coating on the stent framework and means for directing a jet of heated gas towards excess coating portions of the dried polymeric coating that extend into apertures of the stent framework. The system also includes means for reflowing the polymeric coating with the directed jet of heated gas to remove the excess coating portions from the apertures of the stent framework.
Abstract translation: 用于形成药物聚合物涂覆的支架的系统包括将聚合物涂层施加到支架框架的至少一部分上的装置，用于干燥支架框架上施加的聚合物涂层的装置和用于将加热气体射流引导到过量涂层的装置 干燥的聚合物涂层的部分延伸到支架框架的孔中。 该系统还包括用于用引导的加热气体喷射来回流聚合物涂层的装置，以从支架框架的孔中除去多余的涂层部分。
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公开(公告)号：US07105198B2
公开(公告)日：2006-09-12
申请号：US10050219
申请日：2002-01-14
Applicant: Rangarajan Sundar
Inventor： Rangarajan Sundar
IPC: B05D3/12
CPC classification number: B05D1/002 , A61F2250/0067 , A61L31/10 , B05C3/04 , B05C3/10 , B05C11/08 , B05D1/18 , B05D7/50
Abstract: A method of coating a stent includes immersing a portion of the stent into a coating liquid, and withdrawing the immersed portion of the stent from the coating liquid. The stent is simultaneously rotated with respect to the coating liquid while the stent is being immersed and withdrawn.
Abstract translation: 涂布支架的方法包括将支架的一部分浸入涂布液中，并将支架的浸渍部分从涂布液中取出。 当支架被浸入和抽出时，支架相对于涂覆液体同时旋转。
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公开(公告)号：US07575632B2
公开(公告)日：2009-08-18
申请号：US11622269
申请日：2007-01-11
Applicant: Rangarajan Sundar
Inventor： Rangarajan Sundar
IPC: B05C13/00
CPC classification number: A61F2/82 , A61F2/91 , A61F2/915 , A61F2002/91541 , A61F2230/0054 , A61F2240/001 , A61F2250/0067 , B05C3/09 , B05C9/14 , B05C11/1039 , Y10S623/901
Abstract: A system for forming a drug-polymer coated stent includes means for applying a polymeric coating onto at least a portion of a stent framework, means for drying the applied polymeric coating on the stent framework and means for directing a jet of heated gas towards excess coating portions of the dried polymeric coating that extend into apertures of the stent framework. The system also includes means for reflowing the polymeric coating with the directed jet of heated gas to remove the excess coating portions from the apertures of the stent framework.
Abstract translation: 用于形成药物聚合物涂覆的支架的系统包括将聚合物涂层施加到支架框架的至少一部分上的装置，用于干燥支架框架上施加的聚合物涂层的装置和用于将加热气体射流引导到过量涂层的装置 干燥的聚合物涂层的部分延伸到支架框架的孔中。 该系统还包括用于用引导的加热气体喷射来回流聚合物涂层的装置，以从支架框架的孔中除去多余的涂层部分。
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10.发明申请Methods for Compounding and Delivering a Therapeutic Agent to the Adventitia of a Vessel 审中-公开将治疗剂复合并递送至血管外膜的方法公开(公告)号：US20090204104A1
公开(公告)日：2009-08-13
申请号：US11568779
申请日：2005-05-04
Applicant: Patrice Tremble , Dianne Judd , Kishore Udipi , Peiwen Cheng , Rangarajan Sundar , Kaushik A. Patel , Eugene Tedeschi
Inventor： Patrice Tremble , Dianne Judd , Kishore Udipi , Peiwen Cheng , Rangarajan Sundar , Kaushik A. Patel , Eugene Tedeschi
CPC classification number: A61M25/0084 , A61K9/16
Abstract: The invention provides a method of delivering a therapeutic agent to the adventitia of a vessel using a catheter-based microsyringe. A therapeutic agent is formed into microparticles, which are dispersed throughout an appropriate liquid carrier to form a therapeutic mixture. A catheter is provided that includes a microsyringe operably attached to an actuator. The microsyringe includes a hollow needle in fluid communication with a therapeutic agent delivery conduit. The catheter is introduced into a target area of a vessel. The actuator is operated to thrust the needle into a wall of the vessel. The therapeutic mixture is supplied to the therapeutic agent delivery conduit and delivered through the conduit to the needle and thereby into the adventitia of the vessel. The actuator is again operated to withdraw the needle from the wall of the vessel and to enclose it within the actuator. The catheter is then removed from the vessel.
Abstract translation: 本发明提供了使用基于导管的微量注射器将治疗剂递送至血管外膜的方法。 将治疗剂形成为微粒，其分散在适当的液体载体中以形成治疗性混合物。 提供了一种导管，其包括可操作地附接到致动器的微量注射器。 微量注射器包括与治疗剂输送管道流体连通的中空针头。 将导管引入血管的靶区域。 致动器被操作以将针推入容器的壁中。 将治疗性混合物供应到治疗剂递送导管并通过导管输送到针，从而被输送到血管的外膜。 致动器再次被操作以将针从容器的壁中抽出并将其封闭在致动器内。 然后从血管中取出导管。
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