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    Thermocouple-controlled catheter cooling system
    4.
    发明授权
    Thermocouple-controlled catheter cooling system 有权
    热电偶控制导管冷却系统

    公开(公告)号：US09050069B2

    公开(公告)日：2015-06-09

    申请号：US12122436

    申请日：2008-05-16

    申请人： Jean-Pierre Lalonde ,  Dan Wittenberger ,  Marwan Abboud ,  Constantin Bogdan Ciobotaru ,  Ramin Sabbaghe-Kermani

    发明人： Jean-Pierre Lalonde ,  Dan Wittenberger ,  Marwan Abboud ,  Constantin Bogdan Ciobotaru ,  Ramin Sabbaghe-Kermani

    IPC分类号： A61B18/02 ,  A61B18/00 ,  A61M25/01

    CPC分类号： A61B18/02 ,  A61B2018/00023 ,  A61B2018/0022 ,  A61B2018/00797 ,  A61B2018/00821 ,  A61B2018/0212 ,  A61B2018/0262 ,  A61M25/0136

    摘要： The present invention provides a medical system, including a catheter defining an injection lumen, a chamber in fluid communication with the injection lumen, and an exhaust lumen in fluid communication with the chamber; a first temperature sensor positioned in the exhaust lumen proximal to the chamber; a second temperature sensor positioned in the chamber; and a console in electrical communication with the first and second temperature sensors, the controller modifying coolant flow through the medical device based at least in part upon a signal received from the first and second temperature sensor. The system may further include a thermally-conductive element circumscribing a substantial portion of the exhaust lumen proximal to the chamber, where the first temperature sensor is mounted to the thermally-conductive element, and the thermally-conductive element may include at least one of a braid, coil, and band.

    摘要翻译： 本发明提供了一种医疗系统，其包括限定注射腔的导管，与注射腔流体连通的腔室和与腔室流体连通的排气腔; 定位在靠近所述腔室的所述排气腔内的第一温度传感器; 位于所述室中的第二温度传感器; 以及与所述第一和第二温度传感器电连通的控制台，所述控制器至少部分地基于从所述第一和第二温度传感器接收的信号来改变通过所述医疗设备的冷却剂流动。 该系统还可以包括限定靠近腔室的排气腔的主要部分的导热元件，其中第一温度传感器安装到导热元件，并且导热元件可以包括以下中的至少一个： 辫子，线圈和乐队。

    Cryoablation structure
    5.
    发明授权
    Cryoablation structure 有权
    冷冻消融结构

    公开(公告)号：US06270493B1

    公开(公告)日：2001-08-07

    申请号：US09356433

    申请日：1999-07-19

    申请人： Jean-Pierre Lalonde ,  Cristian Petre ,  Robert Martin ,  Claudia Lueckge ,  Sean Carroll ,  Dan Wittenberger ,  George Klein

    发明人： Jean-Pierre Lalonde ,  Cristian Petre ,  Robert Martin ,  Claudia Lueckge ,  Sean Carroll ,  Dan Wittenberger ,  George Klein

    IPC分类号： A61B1818

    CPC分类号： A61B18/02 ,  A61B2017/00026 ,  A61B2017/00084 ,  A61B2018/00041 ,  A61B2018/0022 ,  A61B2018/0212 ,  A61B2018/0268

    摘要： A cryocatheter for treatment of tissue includes a coolant line communicating with a cryochamber having a coolant receiving interior and a thermally conductive wall for contacting and conductively treating tissue. A return line returns spent coolant, and an insert or partition in the cryochamber conditions flow or channels fluid from the coolant line to the return line to enhance the rate or uniformity of cooling. The partition may extend axially to define an elongated sub-chamber which is preferentially cooled, or it may isolate one side to define an uncooled side of the cryochamber. The partition may extend axially to define a sub-chamber extending along a segmented length around a partial circumference of the catheter tip, or may channel the coolant from a central region outwardly against the peripheral wall of the cryochamber. The return line may be a vacuum return line. The catheter may include a means for warming the catheter tip to warm up or accelerate thawing of treated tissue, and the heating may be implemented by a heater in thermal contact with a fluid supply line, which may, moreover, be the coolant supply line. Alternatively, the warming fluid supply line may be distinct from the coolant line. In one embodiment, the device may connect the warming line as an additional coolant return line during cryotreatment, and switch its connection to supply warming fluid after the tissue has been cooled. The catheter may further include sensors such as thermal or impedance sensors for sensing contact orientation of the catheter against adjacent tissue. Electrodes may apply signals of two different frequencies to the two sides, and a processor may determine frequency, impedance or a differential temperature to indicate the tip contact orientation.

    摘要翻译： 用于治疗组织的低温灭菌器包括与具有冷却剂接收内部的冷冻箱和用于接触和导电地处理组织的导热壁连通的冷却剂管线。 返回管路返回耗尽的冷却剂，冷冻箱条件中的插入物或分隔件将流体从冷却剂管路流向或返回管路，以提高冷却速度或均匀性。 分隔件可以轴向延伸以限定优选冷却的细长子室，或者可以隔离一侧以限定冷冻箱的未冷却侧。 分隔件可以轴向延伸以限定围绕导管尖端的部分圆周的分段长度延伸的子室，或者可以将冷却剂从中心区域向外引导抵靠冷冻箱的周壁。 返回管线可以是真空回流管线。 导管可以包括用于加温导管尖端以加热或加速经处理的组织的解冻的装置，并且加热可以通过与流体供应管线热接触的加热器来实现，流体供应管线还可以是冷却剂供应管线。 或者，加温流体供应管线可以不同于冷却剂管线。 在一个实施例中，该装置可以在冷冻处理期间将加热管线作为另外的冷却剂返回管线连接，并且在组织冷却之后将其连接切换到供应加热流体。 导管还可以包括传感器，例如用于感测导管相对于相邻组织的接触取向的热传感器或阻抗传感器。 电极可以将两个不同频率的信号施加到两侧，并且处理器可以确定频率，阻抗或差分温度以指示尖端接触取向。

    Cooling system
    7.
    发明授权
    Cooling system 有权
    冷却系统

    公开(公告)号：US06635053B1

    公开(公告)日：2003-10-21

    申请号：US09638208

    申请日：2000-08-11

    申请人： Jean-Pierre Lalonde ,  Marwan Abboud ,  Rachid Mahrouche ,  Dan Wittenberger

    发明人： Jean-Pierre Lalonde ,  Marwan Abboud ,  Rachid Mahrouche ,  Dan Wittenberger

    IPC分类号： A61B1818

    CPC分类号： A61B18/02 ,  A61B2017/00084 ,  A61B2017/00092 ,  A61B2017/00119 ,  A61B2017/00199 ,  A61B2018/0212 ,  A61B2018/0262 ,  A61B2018/0268

    摘要： A cryogenic medical system includes a medical device and a console connectable to the medical device at a connection point. The console controls the temperature of the medical device. The console includes a first cooling system directing coolant to the medical device at a first temperature along a coolant supply line and a second cooling system chilling the coolant within the coolant supply line to a temperature below the first temperature before the coolant reaches the connection point.

    摘要翻译： 低温医疗系统包括在连接点处可连接到医疗装置的医疗装置和控制台。 控制台控制医疗设备的温度。 所述控制台包括第一冷却系统，所述第一冷却系统沿着冷却剂供应管线在第一温度下将冷却剂引导至所述医疗设备;以及第二冷却系统，在所述冷却剂到达所述连接点之前将所述冷却剂供应管线内的冷却剂冷却至低于所述第一温度的温