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    APPARATUS, PROBE AND METHOD FOR A CRYOGENIC SYSTEM
    1.
    发明申请
    APPARATUS, PROBE AND METHOD FOR A CRYOGENIC SYSTEM 审中-公开
    低温系统的装置，探测和方法

    公开(公告)号：US20150297279A1

    公开(公告)日：2015-10-22

    申请号：US14439883

    申请日：2012-10-30

    申请人： NITRO MEDICAL LIMITED

    发明人： Brian CLARKE

    IPC分类号： A61B18/02

    CPC分类号： A61B18/0218 ,  A61B18/02 ,  A61B2018/00041 ,  A61B2018/0212 ,  A61B2018/0262 ,  A61B2018/0275 ,  A61B2018/0281 ,  A61B2018/0293

    摘要： An apparatus, probe and method for a cryogenic system are described. According to certain embodiments of the invention there is provided an apparatus for cryosurgery comprising: an exhaust line configured to receive cryogen from a probe; and a vacuum source configured to be in fluid communication with the exhaust line.

    摘要翻译： 描述了用于低温系统的装置，探针和方法。 根据本发明的某些实施例，提供了一种用于冷冻手术的装置，包括：排气管线，其构造成从探针接收冷冻剂; 以及构造成与排气管路流体连通的真空源。

    Refrigerant supply system for cryotherapy including refrigerant recompression and associated devices, systems, and methods
    2.
    发明授权
    Refrigerant supply system for cryotherapy including refrigerant recompression and associated devices, systems, and methods 有权
    用于冷冻治疗的制冷剂供应系统，包括制冷剂再压缩及相关设备，系统和方法

    公开(公告)号：US09017317B2

    公开(公告)日：2015-04-28

    申请号：US13707385

    申请日：2012-12-06

    申请人： Medtronic Ardian Luxembourg S.a.r.l.

    发明人： Eric Ryba ,  Gary Kelly

    IPC分类号： A61B18/18 ,  A61B18/02 ,  A61F7/00 ,  A61F7/12 ,  A61B18/00

    CPC分类号： A61B18/02 ,  A61B2018/00648 ,  A61B2018/00672 ,  A61B2018/00744 ,  A61B2018/00863 ,  A61B2018/0212 ,  A61B2018/0262 ,  A61B2018/0275 ,  A61F7/0085 ,  A61F7/12 ,  A61F2007/0056 ,  A61F2007/126

    摘要： Cryotherapeutic systems configured for refrigerant recompression and associated devices, systems, and methods are disclosed herein. A cryotherapeutic system configured in accordance with a particular embodiment includes a high-pressure line, a low-pressure line, a recompression unit, and a cryo-catheter. The recompression unit increases the pressure of refrigerant from the low-pressure line to the high-pressure line to a treatment pressure sufficient for cryogenic alteration of tissue. The high-pressure line and the low-pressure line include, respectively, a first connector and a second connector. The cryo-catheter includes a shaft, a supply lumen in the shaft that is coupled to the first connector, an exhaust lumen in the shaft that is coupled to the second connector, and a cryo-applicator attached to the shaft having a cooling chamber configured to receive refrigerant from the supply lumen and to return refrigerant via the exhaust lumen to the low-pressure line.

    摘要翻译： 配置用于制冷剂再压缩的冷冻治疗系统和相关的装置，系统和方法在本文中公开。 根据特定实施例构造的冷冻治疗系统包括高压管线，低压管线，再压缩单元和低温导管。 再压缩单元将制冷剂从低压管线到高压管线的压力增加到足以对组织进行低温改变的处理压力。 高压线和低压线分别包括第一连接器和第二连接器。 所述冷冻导管包括轴，所述轴中的供应内腔连接到所述第一连接器，所述轴中的与所述第二连接器联接的排气腔，以及附接到所述轴的冷冻涂布器，所述冷却器配置有冷却室 从供应管腔接收制冷剂并且经由排气管将制冷剂返回到低压管线。

    Cryosurgical instrument with vent holes and method using same
    7.
    发明授权
    Cryosurgical instrument with vent holes and method using same 失效
    具有通气孔的冷冻手术器械及其使用方法

    公开(公告)号：US5254116A

    公开(公告)日：1993-10-19

    申请号：US756287

    申请日：1991-09-06

    申请人： John G. Baust ,  ZhaoHua Chang ,  J. J. Finkelstein

    发明人： John G. Baust ,  ZhaoHua Chang ,  J. J. Finkelstein

    IPC分类号： A61B17/00 ,  A61B18/00 ,  A61B18/02 ,  A61F7/12 ,  A61B17/38

    CPC分类号： A61B18/02 ,  A61B2017/00092 ,  A61B2018/00101 ,  A61B2018/0275

    摘要： A closed end surgical cryoprobe instrument with probe shaft diameter of 3 millimeters or less is made to achieve and maintain freezing zone temperatures close to that of the liquid cryogenic refrigerant. Using sub-cooled liquid nitrogen at approximately -208.degree. C. freezing zone temperatures as low as -206.degree. C. can be achieved in under 1 minute. The liquid nitrogen supply tube is provided with a plurality of small vent holes to vent gas formed or present in the refrigerant supply tube to the return refrigerant flow channel. The vent holes also allow small amount of liquid nitrogen to vent into the return flow channel to further reduce the temperature differential between the sub-cooled liquid nitrogen supply and the counter-current flowing return refrigerant.

    摘要翻译： 探头轴直径为3毫米或更小的封闭式手术冷冻探头仪器可以实现并保持冷冻区温度接近于液体低温制冷剂的温度。 在约-208℃下使用低温液氮，在1分钟内可以实现低至-206℃的冷冻区温度。 液氮供给管设置有多个小排气孔，以将形成或存在于制冷剂供给管中的气体排放到返回制冷剂流动通道。 通气孔还允许少量的液氮排放到回流通道中，以进一步降低副冷却液氮供应与逆流回流制冷剂之间的温差。

    CRYOTREATMENT DEVICE AND METHOD
    10.
    发明申请
    CRYOTREATMENT DEVICE AND METHOD 审中-公开
    CRYOTREATMENT设备和方法

    公开(公告)号：US20150018904A1

    公开(公告)日：2015-01-15

    申请号：US14502740

    申请日：2014-09-30

    申请人： Boston Scientific Scimed, Inc.

    发明人： Daniel M. Lafontaine

    IPC分类号： A61F7/10

    CPC分类号： A61F7/10 ,  A61B18/02 ,  A61B2017/00243 ,  A61B2017/00867 ,  A61B2017/22002 ,  A61B2017/22051 ,  A61B2017/22067 ,  A61B2018/00041 ,  A61B2018/00196 ,  A61B2018/0022 ,  A61B2018/0212 ,  A61B2018/0275 ,  A61B2018/0287 ,  A61B2018/1861 ,  A61B2090/0463 ,  A61B2090/064 ,  A61B2090/3782 ,  A61F7/123 ,  A61F2007/0001 ,  A61F2007/0063

    摘要： Devices and methods for cooling vessel walls to inhibit restenosis in conjunction with medical procedures such as coronary artery angioplasty. One catheter device includes a distal tube region having coolant delivery holes radially and longitudinally distributed along the distal region. In some devices, holes spray coolant directly onto the vessel walls. In other embodiments, a balloon or envelope is interposed between the coolant and the vessel walls and the coolant returned out of the catheter through a coolant return lumen. Some direct spray devices include an occlusion device to restrict blood flow past the region being cooled. Pressure, temperature, and ultrasonic probes are included in some cooling catheters. Some cooling catheters are coiled perfusion catheters supporting longer cooling periods by allowing perfusing blood flow simultaneously with vessel wall cooling.

    摘要翻译： 用于冷却血管壁的装置和方法，以与医疗程序如冠状动脉血管成形术结合来抑制再狭窄。 一个导管装置包括远端管区域，其具有沿远端区域径向和纵向分布的冷却剂输送孔。 在一些装置中，孔将冷却剂直接喷射到容器壁上。 在其它实施例中，气囊或外壳插入在冷却剂和容器壁之间，并且冷却剂通过冷却剂返回内腔从导管返回。 一些直接喷射装置包括阻塞装置以限制血液流过被冷却的区域。 压力，温度和超声波探头包括在一些冷却导管中。 一些冷却导管是通过允许血管流动与血管壁冷却同时支持更长的冷却时间的盘绕灌注导管。