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26 条记录 (耗时 0.043 秒)

    Method for treating a patient at risk of loss of cardiac function by cardiac ischemia
    3.
    发明授权
    Method for treating a patient at risk of loss of cardiac function by cardiac ischemia 有权
    用心脏缺血治疗心脏功能丧失危险的患者的方法

    公开(公告)号：US07392077B2

    公开(公告)日：2008-06-24

    申请号：US10822600

    申请日：2004-04-12

    申请人： Richard L. Mueller ,  U. Hiram Chee

    发明人： Richard L. Mueller ,  U. Hiram Chee

    IPC分类号： A61B5/00

    CPC分类号： A61B17/32053 ,  A61B17/3417 ,  A61B17/3478 ,  A61B18/1492 ,  A61B18/22 ,  A61B2017/00247 ,  A61B2018/00392 ,  A61B2090/036

    摘要： Various methods and devices for treating a patient who has lost, or is at risk of losing cardiac function by cardiac ischemia are disclosed. Treatment includes first imaging a patient's heart, or a portion thereof, to identify underperfused regions of cardiac muscle, and a source of oxygenated blood that is proximate to the underperfused region. Between the underperfused regions and the oxygenated blood source, a target area is selected where thermal or mechanical injury is introduced, and optionally reintroduced, to convert initial capillary blush, resulting from the injury.

    摘要翻译： 公开了用于治疗由于心脏缺血而失去或有丧失心脏功能风险的患者的各种方法和装置。 治疗包括首先对患者的心脏或其一部分进行成像以识别心肌的不足灌注区域，以及接近欠灌注区域的充氧血液源。 在欠灌注区域和氧合血液源之间，选择引入热或机械损伤的目标区域，并且可选地重新引入，以转化由损伤引起的初始毛细血管腮红。

    Method and devices for heart treatment
    4.
    发明授权
    Method and devices for heart treatment 有权
    心脏治疗方法和装置

    公开(公告)号：US06748258B1

    公开(公告)日：2004-06-08

    申请号：US09706584

    申请日：2000-11-03

    申请人： Richard L. Mueller ,  U. Hiram Chee

    发明人： Richard L. Mueller ,  U. Hiram Chee

    IPC分类号： A61B505

    CPC分类号： A61B17/32053 ,  A61B17/3417 ,  A61B17/3478 ,  A61B18/1492 ,  A61B18/22 ,  A61B2017/00247 ,  A61B2018/00392 ,  A61B2090/036

    摘要： Various methods and devices for treating a patient who has lost, or is at risk of losing cardiac function by cardiac ischemia are disclosed. Treatment includes first imaging a patient's heart, or a portion thereof, to identify underperfused regions of cardiac muscle, and a source of oxygenated blood that is proximate to the underperfused region. Between the underperfused regions and the oxygenated blood source, a target area is selected where thermal or mechanical injury is introduced, and optionally reintroduced, to convert initial capillary blush, resulting from the injury.

    摘要翻译： 公开了用于治疗由于心脏缺血而失去或有丧失心脏功能风险的患者的各种方法和装置。 治疗包括首先对患者的心脏或其一部分进行成像以识别心肌的不足灌注区域，以及接近欠灌注区域的充氧血液源。 在欠灌注区域和氧合血液源之间，选择引入热或机械损伤的目标区域，并且可选地重新引入，以转化由损伤引起的初始毛细血管腮红。

    Method and monitor for enhancing angiogenesis in the heart by exercise follow-up
    6.
    发明授权
    Method and monitor for enhancing angiogenesis in the heart by exercise follow-up 有权
    通过锻炼随访增强心脏血管生成的方法和监测

    公开(公告)号：US06908435B1

    公开(公告)日：2005-06-21

    申请号：US09706583

    申请日：2000-11-03

    申请人： Richard L. Mueller ,  U. Hiram Chee

    发明人： Richard L. Mueller ,  U. Hiram Chee

    IPC分类号： A61B5/02 ,  A61B5/024 ,  A61B17/00 ,  A61B18/24 ,  A61N7/02

    CPC分类号： A61B5/681 ,  A61B5/02438 ,  A61B18/24 ,  A61B2017/00247 ,  A61B2018/00392 ,  A61N7/02

    摘要： Various methods and devices for treating a patient who has lost, or is at risk of losing cardiac function by cardiac ischemia are disclosed. Treatment includes first imaging a patient's heart, or a portion thereof, to identify underperfused regions of cardiac muscle, and a source of oxygenated blood that is proximate to the underperfused region. Between the underperfused regions and the oxygenated blood source, a target area is selected where thermal or mechanical injury is introduced, and optionally reintroduced, to convert initial capillary blush, resulting from the injury.

    摘要翻译： 公开了用于治疗由于心脏缺血而失去或有丧失心脏功能风险的患者的各种方法和装置。 治疗包括首先对患者的心脏或其一部分进行成像以识别心肌的不足灌注区域，以及接近欠灌注区域的充氧血液源。 在欠灌注区域和氧合血液源之间，选择引入热或机械损伤的目标区域，并且可选地重新引入，以转化由损伤引起的初始毛细血管腮红。

    Photoatherolytic catheter apparatus and method
    9.
    发明授权
    Photoatherolytic catheter apparatus and method 失效
    光疗溶剂导管装置及方法

    公开(公告)号：US07214223B2

    公开(公告)日：2007-05-08

    申请号：US09816832

    申请日：2001-03-22

    申请人： Richard L. Mueller ,  U. Hiram Chee

    发明人： Richard L. Mueller ,  U. Hiram Chee

    IPC分类号： A61B18/22 ,  A61B18/24 ,  A61N5/067

    CPC分类号： A61N5/062 ,  A61B18/245 ,  A61B2018/2261 ,  A61K41/0057 ,  A61K41/0071 ,  A61K47/6957 ,  A61N5/0601 ,  A61N2005/0602

    摘要： A method and apparatus for treating an atherosclerotic target region of a coronary vessel in a patient are disclosed. The method includes delivering to the patient, a photoatherolytic compound, to cause accumulation of the compound in the target region, accessing the target region intraluminally with a guidewire, and advancing over the guidewire, a catheter having (i) a proximal main-body sleeve, (ii) a flexible, non-inflatable, translucent distal-end sleeve joined to the main-body sleeve at a catheter juncture, and (iii) an inner lumen extending through the two sleeves, said advancing being effective to position the catheter's distal-end sleeve within the target region. The guidewire is then removed and replaced by a fiber-optic bundle having a light-diffusing tip, until said tip is positioned adjacent the catheter juncture. After injecting a light-transmissive fluid through the catheter into the catheter's distal-end sleeve, the target vessel region is irradiated by passing a laser light beam through the fiber optic bundle.

    摘要翻译： 公开了一种用于治疗患者的冠状血管的动脉粥样硬化靶区域的方法和装置。 该方法包括向患者输送光解剂，以引起化合物在目标区域中的积聚，用导丝线内光进入目标区域，并在导线上前进;导管，其具有（i）近端主体套筒 ，（ii）在导管接合处连接到主体套管的柔性，不可充气，半透明的远端套筒，以及（iii）延伸穿过两个套筒的内腔，所述前进可有效地定位导管的远端 - 在目标区域内的袖子。 然后将导线移除并由具有光扩散尖端的光纤束代替，直到所述尖端邻近导管接合点定位。 在通过导管将透光流体注入导管的远端套筒之后，通过使激光束穿过光纤束来照射靶血管区域。

    Method and apparatus for recurrent demand injury in stimulating angiogenesis
    10.
    发明授权
    Method and apparatus for recurrent demand injury in stimulating angiogenesis 有权
    刺激血管生成反复需求损伤的方法和装置

    公开(公告)号：US06676679B1

    公开(公告)日：2004-01-13

    申请号：US09706343

    申请日：2000-11-03

    申请人： Richard L. Mueller ,  U. Hiram Chee

    发明人： Richard L. Mueller ,  U. Hiram Chee

    IPC分类号： A61B1734

    CPC分类号： A61B17/3203 ,  A61B17/3207 ,  A61B17/320783 ,  A61B17/3478 ,  A61B90/37 ,  A61B2017/00247 ,  A61B2017/22077 ,  A61B2018/00392 ,  A61B2090/374

    摘要： Various methods and devices for treating a patient who has lost, or is at risk of losing cardiac function by cardiac ischemia are disclosed. Treatment includes first imaging a patient's heart, or a portion thereof, to identify underperfused regions of cardiac muscle, and a source of oxygenated blood that is proximate to the underperfused region. Between the underperfused regions and the oxygenated blood source, a target area is selected where thermal or mechanical injury is introduced, and optionally reintroduced, to convert initial capillary blush, resulting from the injury.

    摘要翻译： 公开了用于治疗由于心脏缺血而失去或有丧失心脏功能风险的患者的各种方法和装置。 治疗包括首先对患者的心脏或其一部分进行成像以识别心肌的不足灌注区域，以及接近欠灌注区域的充氧血液源。 在欠灌注区域和氧合血液源之间，选择引入热或机械损伤的目标区域，并且可选地重新引入，以转化由损伤引起的初始毛细血管腮红。