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1.发明授权公开(公告)号：US08298147B2
公开(公告)日：2012-10-30
申请号：US11473974
申请日：2006-06-23
申请人： Richard Scott Huennekens , Vincent J. Burgess , Marja Pauliina Margolis , Blair D. Walker , Jon D. Klingensmith , Nancy Perry Pool , Randall Kent Hanson
发明人： Richard Scott Huennekens , Vincent J. Burgess , Marja Pauliina Margolis , Blair D. Walker , Jon D. Klingensmith , Nancy Perry Pool , Randall Kent Hanson
IPC分类号： A61B8/00
CPC分类号： A61B6/504 , A61B6/5247 , A61B8/12 , A61B8/5238
摘要： A method and system are disclosed for creating, in a coordinated manner, graphical images of a body including vascular features from a combination of image data sources. The method includes initially creating an angiographic image of a vessel segment. The angiographic image is, for example, either a two or three dimensional image representation. Next, a vessel image data set is acquired that is distinct from the angiographic image data. The vessel image data set comprises information acquired at a series of positions along the vessel segment. An example of such vessel image data is a set of intravascular ultrasound frames corresponding to circumferential cross-section slices taken at various positions along the vessel segment. The angiographic image and the vessel image data set are correlated by comparing a characteristic rendered independently from both the angiographic image and the vessel image data at positions along the vessel segment.
摘要翻译： 公开了用于以协调的方式从图像数据源的组合创建包括血管特征的身体的图形图像的方法和系统。 该方法包括最初创建血管段的血管造影图像。 血管造影图像例如是二维或三维图像表示。 接下来，获取与血管造影图像数据不同的血管图像数据集。 容器图像数据集包括沿着血管段的一系列位置获取的信息。 这样的血管图像数据的一个例子是对应于沿着血管段的不同位置处的圆周横截面切片的一组血管内超声波帧。 血管造影图像和血管图像数据集通过比较沿着血管段的位置独立地从血管造影图像和血管图像数据两者呈现的特征相关联。
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公开(公告)号：US07930014B2
公开(公告)日：2011-04-19
申请号：US11329609
申请日：2006-01-11
申请人： R. Scott Huennekens , Stephen M. Fry , Blair D. Walker , Jon D. Klingensmith , Nancy Perry Pool , Vincent J. Burgess , William R. Kanz
发明人： R. Scott Huennekens , Stephen M. Fry , Blair D. Walker , Jon D. Klingensmith , Nancy Perry Pool , Vincent J. Burgess , William R. Kanz
IPC分类号： A61B5/05
CPC分类号： A61B5/06 , A61B5/0215 , A61B6/12 , A61B6/4441 , A61B6/4494 , A61B6/463 , A61B6/487 , A61B6/504 , A61B6/5247 , A61B8/12 , A61B8/4494 , A61B8/463 , A61B8/543
摘要： A system and method for providing a vascular image are disclosed wherein a single composite display simultaneously provides a first view of a patient including an angiogram image and a second view including an intravascular image rendered from information provided by an imaging probe mounted on a distal end of a flexible elongate member. A cursor, having a position derived from image information provided by a radiopaque marker proximate the imaging probe, is displayed within the angiogram image to correlate the position of the imaging probe to a presently displayed intravascular image and thus provide an easily discernable identification of a position within a patient corresponding to a currently displayed intravascular image. The resulting composite display simultaneously provides: an intravascular image that includes information about a vessel that is not available from an angiogram and a current location within a vessel of a source of intravascular image data from which the intravascular image is rendered.
摘要翻译： 公开了一种用于提供血管图像的系统和方法，其中单个复合显示器同时提供包括血管造影图像的患者的第一视图和第二视图，所述第二视图包括由安装在所述血管图像的远端上的成像探针提供的信息所呈现的血管内图像 柔性细长构件。 具有从靠近成像探针的不透射线标记提供的图像信息导出的位置的光标显示在血管造影图像内，以将成像探针的位置与当前显示的血管内图像相关联，并且因此提供容易辨别的位置识别 在对应于当前显示的血管内图像的患者内。 所得到的复合显示器同时提供：血管内图像，其包括关于从血管造影图不可用的血管的信息和血管内图像来源的血管内图像数据来源的血管内的当前位置。
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公开(公告)号：US07988633B2
公开(公告)日：2011-08-02
申请号：US11250159
申请日：2005-10-12
申请人： Norman Hugh Hossack , Stephen C. Davies , Donald Mamayek , Richard Scott Huennekens , Stephen Fry , Eric V. Mott , Peter Smith , Scott Brownlie , Jon D. Klingensmith , Richard Klosinski , Ed Oliver , Masood Ahmed , Gerald Lea Litzza
发明人： Norman Hugh Hossack , Stephen C. Davies , Donald Mamayek , Richard Scott Huennekens , Stephen Fry , Eric V. Mott , Peter Smith , Scott Brownlie , Jon D. Klingensmith , Richard Klosinski , Ed Oliver , Masood Ahmed , Gerald Lea Litzza
CPC分类号： A61B8/12 , A61B1/00059 , A61B8/4438 , A61B8/4472 , A61B2090/0803 , G06K19/07749
摘要： A method and system is provided for using backscattered data and known parameters to characterize vascular tissue. Specifically, methods and devices for identifying information about the imaging element used to gather the backscattered data are provided in order to permit an operation console having a plurality of Virtual Histology classification trees to select the appropriate VH classification tree for analyzing data gathered using that imaging element. In order to select the appropriate VH database for analyzing data from a specific imaging catheter, it is advantageous to know information regarding the function and performance of the catheter, such as the operating frequency of the catheter and whether it is a rotational or phased-array catheter. The present invention provides a device and method for storing this information on the imaging catheter and communicating the information to the operation console. In addition, information related to additional functions of the catheter may also be stored on the catheter and used to further optimize catheter performance and/or select the appropriate Virtual Histology classification tree for analyzing data from the catheter imaging element.
摘要翻译： 提供了一种使用反向散射数据和已知参数来表征血管组织的方法和系统。 具体地，提供了用于识别关于用于收集背散射数据的成像元件的信息的方法和装置，以便允许具有多个虚拟组织学分类树的操作控制台选择适当的VH分类树，以分析使用该成像元件收集的数据 。 为了选择用于分析来自特定成像导管的数据的适当的VH数据库，有利的是知道关于导管的功能和性能的信息，例如导管的操作频率以及它是旋转的还是相控阵的 导管。 本发明提供了一种用于将该信息存储在成像导管上并将信息传送到操作台的装置和方法。 此外，与导管的附加功能相关的信息也可以存储在导管上并且用于进一步优化导管性能和/或选择适当的虚拟组织学分类树来分析来自导管成像元件的数据。
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公开(公告)号：US08449465B2
公开(公告)日：2013-05-28
申请号：US11580342
申请日：2006-10-14
IPC分类号： A61B8/00
CPC分类号： A61B8/0891 , A61B5/02007 , A61B5/7203 , A61B5/726 , A61B8/0833 , A61B8/12 , A61B8/4461 , A61B8/4488 , A61B8/461 , A61B8/467 , A61B8/52 , A61B8/5238 , G01S7/5205 , G01S7/52087 , G01S15/8977 , G06F19/00
摘要： A system and method is provided for using ultrasound data backscattered from vascular tissue to estimate the transfer function of a catheter and/or substantially synchronizing the acquisition of blood-vessel data to an identifiable portion of heartbeat data. In one embodiment, a computing device and catheter acquire RF backscattered data from a vascular structure. The backscattered ultrasound data is then used to estimate at least one transfer function. The transfer function(s) can then be used to calculate response data for the vascular tissue. Another embodiment includes an IVUS console connected to a catheter and a computing device that acquires RF backscattered data from a vascular structure. Based on the backscattered data, the computing device estimates the catheter's transfer function and to calculate response data for the vascular tissue. The response data and histology data are then used to characterize at least a portion of the vascular tissue.
摘要翻译： 提供了一种用于使用从血管组织反向散射的超声数据来估计导管的传递功能和/或使血管数据的获取基本上同步到心跳数据的可识别部分的系统和方法。 在一个实施例中，计算装置和导管从血管结构获取RF背散射数据。 然后使用后向散射超声数据来估计至少一个传递函数。 然后可以使用传递函数来计算血管组织的反应数据。 另一个实施例包括连接到导管的IVUS控制台和从血管结构获取RF背散射数据的计算设备。 基于背散射数据，计算装置估计导管的传递函数并计算血管组织的反应数据。 然后使用响应数据和组织学数据来表征血管组织的至少一部分。
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公开(公告)号：US20130028497A1
公开(公告)日：2013-01-31
申请号：US13563299
申请日：2012-07-31
IPC分类号： G06K9/00
CPC分类号： G06T7/0012 , A61B5/02007 , A61B8/12 , G06T7/12 , G06T2207/10132 , G06T2207/20101 , G06T2207/30101
摘要： A system and method are provided for using a first vascular image, or more particularly a plurality of control points located thereon, to identify a border on a second vascular image. Embodiments of the present invention operate in accordance with an intra-vascular ultrasound (IVUS) device and a computing device electrically connected thereto. In one embodiment, the computing device includes a plurality of applications operating thereon that are used to (I) identify a border and control points on a first IVUS image (i.e., any IVUS image), (ii) extrapolate the control points to a second IVUS image (i.e., another IVUS image), (iii) identify a border on the second IVUS image, and (iv) adjust the border on the second IVUS image in accordance with at least one factor.
摘要翻译： 提供了一种系统和方法，用于使用位于其上的第一血管图像，或更具体地多个控制点来识别第二血管图像上的边界。 本发明的实施例根据血管内超声（IVUS）装置和与其电连接的计算装置进行操作。 在一个实施例中，计算设备包括多个在其上操作的应用，其用于（I）识别第一IVUS图像（即，任何IVUS图像）上的边界和控制点，（ii）将控制点外推到第二IVUS IVUS图像（即另一IVUS图像），（iii）识别第二IVUS图像上的边界，以及（iv）根据至少一个因素调整第二IVUS图像上的边界。
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公开(公告)号：US20080287795A1
公开(公告)日：2008-11-20
申请号：US12102661
申请日：2008-04-14
IPC分类号： A61B8/12
CPC分类号： G06T7/0012 , A61B5/02007 , A61B8/12 , G06T7/12 , G06T2207/10132 , G06T2207/20101 , G06T2207/30101
摘要： A system and method is provided for using a first vascular image, or more particularly a plurality of control points located thereon, to identify a border on a second vascular image. Embodiments of the present invention operate in accordance with an intra-vascular ultrasound (IVUS) device and a computing device electrically connected thereto. Specifically, in one embodiment of the present invention, an-IVUS console is electrically connected to a computing device and adapted to acquire IVUS data. The IVUS data (or multiple sets thereof) is then provided to (or acquired by) the computing device. In one embodiment of the present invention, the computing device includes a plurality of applications operating thereon—i.e., a border-detection application, an extrapolation application, and an active-contour application. These applications are used to (i) identify a border and control points on a first IVUS image (i.e., any IVUS image), (ii) extrapolate the control points to a second IVUS image (i.e., another IVUS image), (iii) identify a border on the second IVUS image, and (iv) adjust the border on the second IVUS image in accordance with at least one factor. In one embodiment of the present invention, the at least one factor is selected from a group consisting of gradient factor, continuity factor, and curvature factor.
摘要翻译： 提供了一种系统和方法，用于使用位于其上的第一血管图像，或更具体地多个控制点来识别第二血管图像上的边界。 本发明的实施例根据血管内超声（IVUS）装置和与其电连接的计算装置进行操作。 具体来说，在本发明的一个实施例中，-IVUS控制台电连接到计算设备并适于获取IVUS数据。 然后将IVUS数据（或其多组）提供给计算设备（或由其获取）。 在本发明的一个实施例中，计算设备包括在其上操作的多个应用，即边界检测应用，外推应用和主动轮廓应用。 这些应用用于（i）识别第一IVUS图像（即，任何IVUS图像）上的边界和控制点，（ii）将控制点外推到第二IVUS图像（即另一IVUS图像），（iii） 识别第二IVUS图像上的边界，以及（iv）根据至少一个因素调整第二IVUS图像上的边界。 在本发明的一个实施例中，至少一个因素选自由梯度因子，连续性因子和曲率因子组成的组。
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公开(公告)号：US07940969B2
公开(公告)日：2011-05-10
申请号：US11445782
申请日：2006-06-01
CPC分类号： A61B8/12 , A61B5/02007 , A61B5/7257 , A61B5/726 , A61B8/0833 , G06T7/0012 , G06T2207/30101
摘要： A system and method is provided for using backscattered data and known parameters to characterize vascular tissue. Specifically, in one embodiment of the present invention, an ultrasonic device is used to acquire RF backscattered data (i.e., IVUS data) from a blood vessel. The IVUS data is then transmitted to a computing device and used to create an IVUS image. The blood vessel is then cross-sectioned and used to identify its tissue type and to create a corresponding image (i.e., histology image). A region of interest (ROI), preferably corresponding to the identified tissue type, is then identified on the histology image. The computing device, or more particularly, a characterization application operating thereon, is then adapted to identify a corresponding region on the IVUS image. To accurately match the ROI, however, it may be necessary to warp or morph the histology image to substantially fit the contour of the IVUS image. After the corresponding region is identified, the IVUS data that corresponds to this region is identified. Signal processing is then performed and at least one parameter is identified. The identified parameter and the tissue type (e.g., characterization data) is stored in a database. In another embodiment of the present invention, the characterization application is adapted to receive IVUS data, determine parameters related thereto (either directly or indirectly), and use the parameters stored in the database to identify a tissue type or a characterization thereof.
摘要翻译： 提供了一种使用背散射数据和已知参数来表征血管组织的系统和方法。 具体地，在本发明的一个实施例中，使用超声波装置从血管获取RF背散射数据（即，IVUS数据）。 然后将IVUS数据传输到计算设备并用于创建IVUS图像。 然后将血管切片并用于识别其组织类型并产生相应的图像（即，组织学图像）。 然后在组织学图像上识别优选对应于所识别的组织类型的感兴趣区域（ROI）。 然后，计算设备，或更具体地，在其上操作的表征应用程序适用于识别IVUS图像上的对应区域。 然而，为了精确地匹配ROI，可能需要使组织学图像变形或变形以基本上适合IVUS图像的轮廓。 识别对应区域后，识别与该区域对应的IVUS数据。 然后执行信号处理，并且识别至少一个参数。 所识别的参数和组织类型（例如表征数据）被存储在数据库中。 在本发明的另一个实施例中，表征应用适于接收IVUS数据，确定与其相关的参数（直接或间接），并且使用存储在数据库中的参数来识别组织类型或其表征。
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公开(公告)号：US07175597B2
公开(公告)日：2007-02-13
申请号：US10356812
申请日：2003-02-03
IPC分类号： A61B8/00
CPC分类号： A61B8/00 , A61B5/02007 , A61B5/7264 , A61B8/0825
摘要： One embodiment of the present system and method is directed to the identification of tissues within a vascular object by analyzing ultrasound data collected from the vascular object by non-invasive scans. By identifying and characterizing types of tissue from ultrasound data, an assessment can be made about the health condition of a patient without an invasive procedure. Other applications of the present system will also be appreciated including identifying other types of tissues.
摘要翻译： 本系统和方法的一个实施例涉及通过非侵入性扫描分析从血管对象收集的超声数据来识别血管对象内的组织。 通过从超声数据中识别和表征组织的类型，可以对没有侵入性程序的患者的健康状况进行评估。 还将理解本系统的其它应用，包括识别其他类型的组织。
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9.发明授权公开(公告)号：US06381350B1
公开(公告)日：2002-04-30
申请号：US09347209
申请日：1999-07-02
IPC分类号： G06K900
CPC分类号： A61B8/4461 , A61B5/02007 , A61B5/1076 , A61B8/0833 , A61B8/0858 , A61B8/12 , A61B8/463 , G06K9/6207 , G06T7/12 , G06T7/149 , G06T2207/10132 , G06T2207/20101 , G06T2207/30101
摘要： An intravascular ultrasound (IVUS) analysis system and method is provided which determines luminal and medial-adventitial boundaries of a blood vessel. Ultrasonic data is acquired by a rotating transducer mounted to a tip of a catheter which is inserted into the blood vessel. An intravascular image is reconstructed from the ultrasound data. To determine the luminal boundary of a vessel, a user selects boundary points on the image believed to be locations of the luminal boundary. A boundary contour is generated based on the boundary points. The boundary contour is then optimized by adjusting the boundary points based on a radially determined edge of the luminal boundary performed on the image in polar format. Once the final luminal boundary contour is generated, the process is repeated to determine the medial-adventitial boundary contour. With the contour data, properties of the blood vessel are analyzed including determining the area of the lumen and percent of occlusion caused by plaque.
摘要翻译： 提供了一种血管内超声（IVUS）分析系统和方法，其确定血管的腔内和外侧 - 外膜边界。 通过安装到插入血管的导管的尖端的旋转传感器来获取超声数据。 从超声数据重建血管内图像。 为了确定容器的管腔边界，用户选择被认为是管腔边界位置的图像上的边界点。 基于边界点生成边界轮廓。 然后通过基于以极性格式对图像执行的腔边界的径向确定的边缘调整边界点来优化边界轮廓。 一旦产生最终的管腔边界轮廓，重复该过程以确定内侧 - 外膜边界轮廓。 使用轮廓数据，分析血管的性质，包括确定管腔面积和由斑块引起的闭塞百分比。
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公开(公告)号：US08808183B2
公开(公告)日：2014-08-19
申请号：US12878770
申请日：2010-09-09
IPC分类号： A61B8/00
CPC分类号： A61B5/02007 , A61B5/726 , A61B8/12
摘要： A system and method is provided for using ultrasound data backscattered from vascular tissue to estimate the transfer function of a catheter (including components attached thereto—e.g., IVUS console, transducer, etc.). Specifically, in accordance with a first embodiment of the present invention, a computing device is electrically connected to a catheter and used to acquire RF backscattered data from a vascular structure (e.g., a blood vessel, etc.). The backscattered ultrasound data is then used, together with an algorithm, to estimate the transfer function. The transfer function can then be used (at least in a preferred embodiment) to calculate response data for the vascular tissue (i.e., the tissue component of the backscattered ultrasound data). In a second embodiment of the present invention, an IVUS console is electrically connected to a catheter and a computing device and is used to acquire RF backscattered data from a vascular structure. The backscattered data is then transmitted to the computing device, where it is used to estimate the catheter's transfer function and to calculate response data for the vascular tissue. The response data and histology data are then used to characterize at least a portion of the vascular tissue (e.g., identify tissue type, etc.).
摘要翻译： 提供了一种系统和方法，用于使用从血管组织反向散射的超声数据来估计导管（包括与其连接的部件，例如，IVUS控制台，换能器等）的传递功能。 具体地，根据本发明的第一实施例，计算设备电连接到导管并用于从血管结构（例如，血管等）获取RF背散射数据。 然后将后向散射的超声数据与算法一起用于估计传递函数。 然后可以使用传递函数（至少在一个优选实施例中）来计算血管组织的反应数据（即背散射超声数据的组织分量）。 在本发明的第二实施例中，IVUS控制台电连接到导管和计算设备，并用于从血管结构获取RF背散射数据。 然后将背散射数据传输到计算设备，其中其用于估计导管的传递函数并计算血管组织的反应数据。 然后使用响应数据和组织学数据来表征血管组织的至少一部分（例如，识别组织类型等）。
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