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    Luminometer with reduced sample crosstalk
    1.
    发明授权
    Luminometer with reduced sample crosstalk 失效
    发光计具有减少的样品串扰

    公开(公告)号：US5716583A

    公开(公告)日：1998-02-10

    申请号：US411445

    申请日：1995-03-28

    Applicant: Rick T. Smethers ,  Brian D. Warner ,  Victor P. Burolla

    Inventor： Rick T. Smethers ,  Brian D. Warner ,  Victor P. Burolla

    IPC: G01N21/64 ,  G01N21/03 ,  G01N21/76 ,  G01N21/78 ,  G01N33/532 ,  G01N33/536 ,  G01N33/543 ,  G01N35/00 ,  G01N35/02 ,  G01N35/04 ,  G01N21/29

    CPC classification number: G01N21/76 ,  G01N35/028 ,  G01N2035/00376 ,  G01N2035/0487 ,  Y10S435/808

    Abstract: A luminometer is described comprising a tray for receiving an array of sample wells, a photodetector assembly, and means for relatively moving the tray and photodetector assembly in one direction to align the sample wells received by the tray in a predetermined sequence with the photodetector assembly. The photodetector assembly of the luminometer includes a stage, a photodetection head having a detection aperture permitting passage of light therethrough, a means for mounting the photodetection head to the stage that permits movement of the head in a direction substantially normal to the direction of relative tray and photodetector assembly movement, and a means for biasing the photodetection head toward a selected sample well so that the detection aperture is substantially isolated from light emitted from adjacent wells. Internal and external photodetector calibration systems and a sample heater are also contemplated.

    Abstract translation: 描述了一种光度计，其包括用于接收样品阱阵列的光盘，光电检测器组件和用于在一个方向上使托盘和光电检测器组件相对移动的装置，以使由托盘接收的样品阱以预定顺序与光电检测器组件对准。 光度计的光电检测器组件包括一个台，具有允许光通过的检测孔的光电检测头，用于将光电检测头安装到台架上的装置，该装置允许头沿基本上垂直于相对托盘的方向移动 和光电检测器组件移动，以及用于将光电检测头朝向所选样本阱偏置的装置，使得检测孔径基本上与从相邻孔发射的光隔离。 还考虑了内部和外部光电探测器校准系统和样品加热器。

    Luminometer with reduced sample crosstalk
    2.
    发明授权
    Luminometer with reduced sample crosstalk 失效
    发光计具有减少的样品串扰

    公开(公告)号：US5643535A

    公开(公告)日：1997-07-01

    申请号：US439196

    申请日：1995-05-11

    Applicant: Rick T. Smethers ,  Brian D. Warner ,  Victor P. Burolla

    Inventor： Rick T. Smethers ,  Brian D. Warner ,  Victor P. Burolla

    IPC: G01N21/64 ,  G01N21/03 ,  G01N21/76 ,  G01N21/78 ,  G01N33/532 ,  G01N33/536 ,  G01N33/543 ,  G01N35/00 ,  G01N35/02 ,  G01N35/04 ,  G01N21/01

    CPC classification number: G01N21/76 ,  G01N35/028 ,  G01N2035/00376 ,  G01N2035/0487 ,  Y10S435/808

    Abstract: A luminometer is described comprising a tray for receiving an array of sample wells, a photodetector assembly, and means for relatively moving the tray and photodetector assembly in one direction to align the sample wells received by the tray in a predetermined sequence with the photodetector assembly. The photodetector assembly of the luminometer includes a stage, a photodetection head having a detection aperture permitting passage of light therethrough, a means for mounting the photodetection head to the stage that permits movement of the head in a direction substantially normal to the direction of relative tray and photodetector assembly movement, and a means for biasing the photodetection head toward a selected sample well so that the detection aperture is substantially isolated from light emitted from adjacent wells. Internal and external photodetector calibration systems and a sample heater are also contemplated.

    Abstract translation: 描述了一种光度计，其包括用于接收样品阱阵列的光盘，光电检测器组件和用于在一个方向上使托盘和光电检测器组件相对移动的装置，以使由托盘接收的样品阱以预定顺序与光电检测器组件对准。 光度计的光电检测器组件包括一个台，具有允许光通过的检测孔的光电检测头，用于将光电检测头安装到台架上的装置，该装置允许头沿基本上垂直于相对托盘的方向移动 和光电检测器组件移动，以及用于将光电检测头朝向所选样本阱偏置的装置，使得检测孔径基本上与从相邻孔发射的光隔离。 还考虑了内部和外部光电探测器校准系统和样品加热器。

    Luminometer with reduced sample crosstalk
    3.
    发明授权
    Luminometer with reduced sample crosstalk 失效
    发光计具有减少的样品串扰

    公开(公告)号：US5401465A

    公开(公告)日：1995-03-28

    申请号：US878829

    申请日：1992-05-05

    Applicant: Rick T. Smethers ,  Brian D. Warner ,  Victor P. Burolla

    Inventor： Rick T. Smethers ,  Brian D. Warner ,  Victor P. Burolla

    IPC: G01N21/64 ,  G01N21/03 ,  G01N21/76 ,  G01N21/78 ,  G01N33/532 ,  G01N33/536 ,  G01N33/543 ,  G01N35/00 ,  G01N35/02 ,  G01N35/04

    CPC classification number: G01N21/76 ,  G01N35/028 ,  G01N2035/00376 ,  G01N2035/0487 ,  Y10S435/808

    Abstract: A luminometer comprising a tray for receiving an array of sample wells, a photodetector assembly, and device for relatively moving the tray and photodetector assembly in one direction to align the sample wells received by the tray in a predetermined sequence with the photodetector assembly. The photodetector assembly of the luminometer includes a stage, a photodetection head having a detection aperture permitting passage of light therethrough, a device for mounting the photodetection head to the stage that permits movement of the head in a direction substantially normal to the direction of relative tray and photodetector assembly movement, and a device for biasing the photodetection head toward a selected sample well so that the detection aperture is substantially isolated from light emitted from adjacent wells. Internal and external photodetector calibration systems and a sample heater are also contemplated.

    Abstract translation: 一种发光计，包括用于接收样品阱阵列的光盘，光电检测器组件和用于使托盘和光电检测器组件在一个方向上相对移动的装置，以使由托盘接收的样品阱以预定顺序与光电检测器组件对准。 该发光计的光电检测器组件包括一台，具有允许光通过的检测孔的光电检测头，用于将光电检测头安装到台架上的装置，该装置允许头沿基本上垂直于相对托盘方向移动 和光电检测器组件移动，以及用于将光电检测头朝向所选样本阱偏置的装置，使得检测孔与从相邻孔发射的光基本上隔离。 还考虑了内部和外部光电探测器校准系统和样品加热器。

    Apparatus and device for use therein and method for ablation of tissue
    7.
    发明授权
    Apparatus and device for use therein and method for ablation of tissue 失效
    用于其中的装置和装置及其组织消融方法

    公开(公告)号：US6102907A

    公开(公告)日：2000-08-15

    申请号：US912273

    申请日：1997-08-15

    Applicant: Rick T. Smethers ,  James A. Filice ,  Kirti P. Kamdar ,  Peter H. Muller

    Inventor： Rick T. Smethers ,  James A. Filice ,  Kirti P. Kamdar ,  Peter H. Muller

    IPC: A61B17/24 ,  A61B18/12 ,  A61B18/14 ,  A61B18/18

    CPC classification number: A61B18/1477 ,  A61B2018/00755 ,  A61B2018/00821 ,  A61B2018/00875 ,  A61B2018/1253 ,  A61B2018/1475

    Abstract: A device for the ablation of tissue for use with the human hand and a radio frequency power supply and controller providing a source of radio frequency energy and a control for controlling the application of radio frequency energy to the device. The device includes a handle sized so that is adapted to be grasped by the human hand and has proximal and distal extremities. A needle formed of a conducting material has proximal and distal extremities. The proximal extremity of the needle is mounted on the distal extremity of the handle so that it is insulated from the handle. Conductors are carried by the handle and are connected to the needle and extend from the handle and are coupled to the radio frequency power supply and controller for supplying radio frequency energy to the needle. A temperature sensor is carried by the handle and is adapted to be coupled to the radio frequency power supply and controller for sensing the application of radio frequency energy to the tissue for controlling the application of radio frequency energy to the needle.

    Abstract translation: 用于消除用于人手的组织的装置和提供射频能量源的射频电源和控制器以及用于控制将射频能量应用于该装置的控制。 该装置包括尺寸适于被人的手抓住并具有近端和远端的手柄。 由导电材料形成的针头具有近端和远端。 针的近端被安装在手柄的远端上，使得其与手柄绝缘。 导体由手柄承载并连接到针上并从手柄延伸并且耦合到射频电源和控制器以向针提供射频能量。 温度传感器由手柄承载，并且适于耦合到射频电源和控制器，用于感测向组织施加射频能量，以控制向针施加射频能量。

    Tissue ablation apparatus and device for use therein and method
    10.
    发明授权
    Tissue ablation apparatus and device for use therein and method 失效
    组织消融装置及其使用的装置及方法

    公开(公告)号：US6045549A

    公开(公告)日：2000-04-04

    申请号：US941401

    申请日：1997-09-30

    Applicant: Rick T. Smethers ,  Benjamin T. Nordell, II

    Inventor： Rick T. Smethers ,  Benjamin T. Nordell, II

    IPC: A61B18/00 ,  A61B18/14 ,  A61B17/39

    CPC classification number: A61B18/1477 ,  A61B2018/00023 ,  A61B2018/00577 ,  A61B2018/00654 ,  A61B2018/00791 ,  A61B2018/00797 ,  A61B2018/0091 ,  A61B2018/00916

    Abstract: A tissue ablation apparatus for minimally invasive treatment for disorders of the upper airway by the treatment of soft tissues in the upper airway comprising a hand-held device adapted to be held by the human hand. Radio frequency energy is delivered to the hand-held device. The hand-held device comprises a housing having a handle portion adapted to be grasped by the human hand and a probe portion. At least one guide tube is mounted in the probe portion and has a bore extending therethrough. A carrier block is slidably mounted in the housing relative to the guide tube. At least one needle assembly is mounted in the carrier block assembly and is movable with the carrier block assembly. The at least one needle assembly extends distally of the carrier block and is slidably disposed in the at least one guide tube. A slider is mounted on the housing exterior of the housing for slidable movement longitudinally of the housing and is adapted to be grasped by the thumb of the hand holding the housing. The slider is connected to the carrier block whereby when the slider is moved distally, the carrier block with the needle assembly is moved in the guide tube distally of the guide tube for entrance into the soft tissue.

    Abstract translation: 一种用于通过治疗上气道中的软组织来治疗上呼吸道疾病的微创治疗的组织消融装置，包括适于由人手保持的手持装置。 射频能量传送到手持设备。 手持式装置包括壳体，该壳体具有适于由人手抓握的手柄部分和探针部分。 至少一个导管安装在探针部分中并且具有延伸穿过其中的孔。 载体块相对于导管可滑动地安装在壳体中。 至少一个针组件安装在承载块组件中并且可与承载块组件一起移动。 所述至少一个针组件在所述承载块的远侧延伸并且可滑动地设置在所述至少一个引导管中。 滑动件安装在壳体的壳体外部上，用于可滑动地移动到壳体的纵向，并且适于由握住壳体的手的拇指来抓握滑块。 滑块连接到承载块，由此当滑块向远侧移动时，具有针组件的承载块在引导管中在引导管的远侧移动以进入软组织。

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