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公开(公告)号:US20120191003A1
公开(公告)日:2012-07-26
申请号:US13437214
申请日:2012-04-02
IPC分类号: A61B5/05
CPC分类号: A61N1/0551 , A61B5/04001 , A61B5/0488 , A61B5/1107 , A61B5/4519 , A61B5/4893 , A61B17/149 , A61B17/1671 , A61B17/1757 , A61B17/320016 , A61B17/7092 , A61B17/8897 , A61B2017/32006 , A61B2562/0261 , A61B2562/046
摘要: Described herein are bimanually controlled neural localization devices capable of determining if a nerve is nearby a region of the device. In general, the device may include at least two electrodes including an anode in electrical communication with a anodal conductor and a cathode in electrical communication with a cathodal conductor. The device may further include a flexible elongate body, wherein the flexible elongate body has an axial length, a width and a thickness, wherein the axial length is greater than the width, and the width is greater than the thickness and is greater than a width of the at least two electrodes. The at least two electrodes may be disposed substantially in-line and centered along the length of the elongate body. In some embodiments, the device may further include a guidewire coupler at the distal end region of the elongate body.
摘要翻译: 这里描述的是能够确定神经是否在装置的区域附近的双手控制的神经定位装置。 通常,该装置可以包括至少两个电极,包括与阳极导体电连通的阳极和与阴极导体电连通的阴极。 该装置还可以包括柔性细长主体,其中柔性细长主体具有轴向长度,宽度和厚度,其中轴向长度大于宽度,并且宽度大于厚度并且大于宽度 的至少两个电极。 所述至少两个电极可以沿着细长主体的长度基本上一直排列并居中。 在一些实施例中,该装置还可包括在细长主体的远端区域处的导丝联接器。
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公开(公告)号:US20140114315A1
公开(公告)日:2014-04-24
申请号:US14061641
申请日:2013-10-23
IPC分类号: A61B17/16
CPC分类号: A61B17/1671 , A61B17/149 , A61B17/1659
摘要: Tissue modification devices, methods of using them, and devices, systems and methods of adapting them to form tissue modification devices.
摘要翻译: 组织修饰装置,使用它们的方法,以及适应它们以形成组织修饰装置的装置,系统和方法。
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公开(公告)号:US08409206B2
公开(公告)日:2013-04-02
申请号:US12773595
申请日:2010-05-04
申请人: Michael P. Wallace , Robert Garabedian , Nestor C. Cantorna , Jeffery L. Bleich , Roy Leguidleguid , Ronald Leguidleguid
发明人: Michael P. Wallace , Robert Garabedian , Nestor C. Cantorna , Jeffery L. Bleich , Roy Leguidleguid , Ronald Leguidleguid
IPC分类号: A61B17/00
CPC分类号: A61B17/025 , A61B5/4893 , A61B17/0218 , A61B17/7062 , A61B2017/0256 , A61B2017/32006 , A61M25/01 , A61M25/0105 , A61M25/0133 , A61M25/0136 , A61M25/09 , A61M29/02
摘要: Described herein are devices, systems and methods for cutting tissue in a patient. In some embodiments, a tissue modification region of a device includes a pair of flexible elongate cutting members extending along the length of the tissue modification region. Each elongate cutting member may be configured to cut a discrete trough into tissue to a depth that is greater than the thickness of the cutting member. In some embodiments, the device includes a spacer. The spacer may be sized and configured to operate in one of two modes. A first mode, in which the spacer is coupled to the cutting members such that it holds a portion of each of the two cutting members a distance from one another, and a second mode, in which at least a portion of the spacer is moved away from a cutting member to allow the cutting members to cut further into tissue.
摘要翻译: 这里描述了用于切割患者组织的装置,系统和方法。 在一些实施例中,装置的组织修改区域包括沿着组织修改区域的长度延伸的一对柔性细长切割构件。 每个细长的切割构件可以被配置成将离散的槽切割成组织到比切割构件的厚度大的深度。 在一些实施例中,该装置包括间隔件。 间隔件的尺寸和构造可以以两种模式之一来操作。 第一模式,其中间隔件联接到切割构件,使得其将两个切割构件中的每一个的一部分保持彼此的距离,以及第二模式,其中至少一部分间隔件移开 从切割构件允许切割构件进一步切割成组织。
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公开(公告)号:US20100274250A1
公开(公告)日:2010-10-28
申请号:US12773595
申请日:2010-05-04
申请人: Michael P. Wallace , Robert Garabedian , Nestor C. Cantorna , Jeffery L. Bleich , Roy Leguidleguid , Ronald Leguidleguid
发明人: Michael P. Wallace , Robert Garabedian , Nestor C. Cantorna , Jeffery L. Bleich , Roy Leguidleguid , Ronald Leguidleguid
IPC分类号: A61B17/16
CPC分类号: A61B17/025 , A61B5/4893 , A61B17/0218 , A61B17/7062 , A61B2017/0256 , A61B2017/32006 , A61M25/01 , A61M25/0105 , A61M25/0133 , A61M25/0136 , A61M25/09 , A61M29/02
摘要: Described herein are devices, systems and methods for cutting tissue in a patient. In some embodiments, a tissue modification region of a device includes a pair of flexible elongate cutting members extending along the length of the tissue modification region. Each elongate cutting member may be configured to cut a discrete trough into tissue to a depth that is greater than the thickness of the cutting member. In some embodiments, the device includes a spacer. The spacer may be sized and configured to operate in one of two modes. A first mode, in which the spacer is coupled to the cutting members such that it holds a portion of each of the two cutting members a distance from one another, and a second mode, in which at least a portion of the spacer is moved away from a cutting member to allow the cutting members to cut further into tissue.
摘要翻译: 这里描述了用于切割患者组织的装置,系统和方法。 在一些实施例中,装置的组织修改区域包括沿着组织修改区域的长度延伸的一对柔性细长切割构件。 每个细长的切割构件可以被配置成将离散的槽切割成组织到比切割构件的厚度大的深度。 在一些实施例中,该装置包括间隔件。 间隔件的尺寸和构造可以以两种模式之一来操作。 第一模式,其中间隔件联接到切割构件,使得其将两个切割构件中的每一个的一部分保持彼此的距离,以及第二模式,其中至少一部分间隔件移开 从切割构件允许切割构件进一步切割成组织。
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公开(公告)号:US20120095468A1
公开(公告)日:2012-04-19
申请号:US13338103
申请日:2011-12-27
申请人: Michael P. Wallace , Robert Garabedian , Nestor C. Cantorna , Jeffery L. Bleich , Roy Leguidleguid , Ronald Leguidleguid
发明人: Michael P. Wallace , Robert Garabedian , Nestor C. Cantorna , Jeffery L. Bleich , Roy Leguidleguid , Ronald Leguidleguid
IPC分类号: A61B17/16
CPC分类号: A61B17/025 , A61B5/4893 , A61B17/0218 , A61B17/1671 , A61B17/32 , A61B17/320016 , A61B17/7032 , A61B17/7062 , A61B17/864 , A61B2017/0256 , A61B2017/32006
摘要: Described herein are devices and methods for cutting tissue in a patient. In some embodiments, a bimanually controlled device may include a tissue modification region; at least two flexible elongate lengths of cable that extend substantially adjacent to each other proximally to distally; a plurality of rungs extending between the lengths of cable; and a pair of flexible elongate cutting members extending along the length of the tissue modification region of the device. Each elongate cutting member has a thickness cuts a discrete trough into tissue to a depth that is greater than the thickness of the cutting member. The device may further include a substrate sized and configured to releasably hold the cutting members a distance from one another and a pair of couplers positioned toward an outer edge region of the substrate and configured to releasably secure a cutting member to the outer edge region of the substrate.
摘要翻译: 本文描述了用于在患者体内切割组织的装置和方法。 在一些实施例中,双手控制的装置可以包括组织修改区域; 至少两个柔性长度的电缆,其基本上彼此相邻地向远侧延伸延伸; 在电缆长度之间延伸的多个梯级; 以及沿设备的组织修改区域的长度延伸的一对柔性细长切割构件。 每个细长的切割构件具有将离散凹槽切割成组织的厚度,其厚度大于切割构件的厚度。 该装置还可以包括基板,其尺寸和构造为将切割构件可释放地保持彼此间隔一定距离;以及一对耦合器,其朝向基板的外边缘区域定位,并且构造成将切割构件可释放地固定到外部边缘区域 基质。
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公开(公告)号:US08845639B2
公开(公告)日:2014-09-30
申请号:US13007381
申请日:2011-01-14
申请人: Michael P. Wallace , Robert Garabedian , Gregory P. Schmitz , Jeffery L. Bleich , Nestor C. Cantorna , Ronald Leguidleguid , Roy Leguidleguid , Michael Sheinberg
发明人: Michael P. Wallace , Robert Garabedian , Gregory P. Schmitz , Jeffery L. Bleich , Nestor C. Cantorna , Ronald Leguidleguid , Roy Leguidleguid , Michael Sheinberg
CPC分类号: A61B17/1671 , A61B17/149 , A61B17/1659 , A61B17/320016 , A61B17/32002 , A61B17/3207 , A61B2017/00261 , A61B2017/320004 , A61B2017/320008 , A61B2017/32006 , A61B2017/32008 , A61B2090/3925 , A61B2090/3954 , A61B2090/3966
摘要: Described herein are elongate devices for modifying tissue having a plurality of flexibly connected and rungs or links, and methods of using them, including methods of using them to decompress stenotic spinal tissue. These devices may be included as part of a system for modifying tissue. In general, these devices include a plurality of blades positioned on for formed from) rungs that are flexibly connected and may be separated by one or more spacers. The rungs are typically wider than they are long (e.g., rectangular). The rungs may be arranged, ladder like, and may be connected by a flexible connector substrate or between two or more cables. Different sized rungs may be used, or rungs with different cutting properties. In some variations the tissue modification devices may have a non-linear axial shape, or may be converted from a first axial shape to a second axial shape.
摘要翻译: 本文描述的是用于修改具有多个柔性连接和梯级或链节的组织的细长装置,以及使用它们的方法,包括使用它们来减压狭窄的脊髓组织的方法。 可以将这些装置作为用于修改组织的系统的一部分。 通常,这些装置包括多个叶片,其位于用于形成的梯级上,所述多个叶片被柔性地连接并且可被一个或多个间隔件隔开。 梯级通常比它们长(例如,矩形)宽。 梯级可以布置成梯子,并且可以通过柔性连接器基板或两根或更多根电缆连接。 可以使用不同尺寸的梯级,或者具有不同切割性能的梯级。 在一些变型中,组织改变装置可以具有非线性轴向形状,或者可以从第一轴向形状转换成第二轴向形状。
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公开(公告)号:US08398641B2
公开(公告)日:2013-03-19
申请号:US13338103
申请日:2011-12-27
申请人: Michael P. Wallace , Robert Garabedian , Nestor C. Cantorna , Jeffery L. Bleich , Roy Leguidleguid , Ronald Leguidleguid
发明人: Michael P. Wallace , Robert Garabedian , Nestor C. Cantorna , Jeffery L. Bleich , Roy Leguidleguid , Ronald Leguidleguid
IPC分类号: A61B17/00
CPC分类号: A61B17/025 , A61B5/4893 , A61B17/0218 , A61B17/1671 , A61B17/32 , A61B17/320016 , A61B17/7032 , A61B17/7062 , A61B17/864 , A61B2017/0256 , A61B2017/32006
摘要: Described herein are devices and methods for cutting tissue in a patient. In some embodiments, a bimanually controlled device may include a tissue modification region; at least two flexible elongate lengths of cable that extend substantially adjacent to each other proximally to distally; a plurality of rungs extending between the lengths of cable; and a pair of flexible elongate cutting members extending along the length of the tissue modification region of the device. Each elongate cutting member has a thickness cuts a discrete trough into tissue to a depth that is greater than the thickness of the cutting member. The device may further include a substrate sized and configured to releasably hold the cutting members a distance from one another and a pair of couplers positioned toward an outer edge region of the substrate and configured to releasably secure a cutting member to the outer edge region of the substrate.
摘要翻译: 本文描述了用于在患者体内切割组织的装置和方法。 在一些实施例中,双手控制的装置可以包括组织修改区域; 至少两个柔性长度的电缆,其基本上彼此相邻地向远侧延伸延伸; 在电缆长度之间延伸的多个梯级; 以及沿设备的组织修改区域的长度延伸的一对柔性细长切割构件。 每个细长的切割构件具有将离散凹槽切割成组织的厚度,其厚度大于切割构件的厚度。 该装置还可以包括基板,其尺寸和构造为将切割构件可释放地保持彼此间隔一定距离;以及一对耦合器,其朝向基板的外边缘区域定位,并且构造成将切割构件可释放地固定到外部边缘区域 基质。
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公开(公告)号:US20110060314A1
公开(公告)日:2011-03-10
申请号:US12911537
申请日:2010-10-25
申请人: Michael P. Wallace , Robert Garabedian , Gregory B. Arcenio , Jeffery L. Bleich , Vahid Saadat , Winnie Chung
发明人: Michael P. Wallace , Robert Garabedian , Gregory B. Arcenio , Jeffery L. Bleich , Vahid Saadat , Winnie Chung
CPC分类号: A61B17/32 , A61B17/149 , A61B17/1659 , A61B17/1671 , A61B17/320016 , A61B17/3401 , A61B17/3403 , A61B17/3468 , A61B18/1477 , A61B18/1487 , A61B90/04 , A61B2017/00261 , A61B2017/003 , A61B2017/00331 , A61B2017/00867 , A61B2017/22038 , A61B2017/22049 , A61B2017/320004 , A61B2017/320044 , A61B2017/32006 , A61B2018/1407 , A61B2018/1425 , A61B2090/061 , A61B2090/08021 , A61F2/0045 , A61M25/0067 , A61M25/09 , A61M2210/1003 , A61N1/0551 , A61N1/36017
摘要: Described herein are devices, systems and methods for treating target tissue in a patient's spine. In general, the methods include the steps of advancing a wire into the patient from a first location, through a neural foramen, and out of the patient from a second location; connecting a tissue modification device to the wire; positioning the tissue modification device through the neural foramen using the wire; modifying target tissue in the spine by moving the tissue modification device against the target tissue; and delivering an agent to modified target tissue, wherein the agent is configured to inhibit blood flow from the modified target tissue. In some embodiments, the step of modifying target tissue comprises removing target tissue located ventral to the superior articular process while avoiding non-target tissue located lateral to the superior articular process.
摘要翻译: 本文描述了用于治疗患者脊柱中的靶组织的装置,系统和方法。 通常,所述方法包括以下步骤:从第一位置,通过神经孔进入患者,并从第二位置离开患者; 将组织修改装置连接到所述线; 通过使用丝线的神经孔定位组织修饰装置; 通过将组织改变装置移动到目标组织上来改变脊柱中的目标组织; 以及将药剂递送至修饰的靶组织,其中所述药剂被配置为抑制来自所述修饰的靶组织的血液流动。 在一些实施方案中,修饰靶组织的步骤包括去除位于上关节进程的腹侧的靶组织,同时避免位于上关节突侧的非靶组织。
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公开(公告)号:US20090177194A1
公开(公告)日:2009-07-09
申请号:US12404159
申请日:2009-03-13
IPC分类号: A61B18/00
CPC分类号: A61B18/18 , A61B18/02 , A61B18/1492 , A61B18/1815 , A61B34/71 , A61B90/50 , A61B2017/00296 , A61B2018/0022 , A61B2018/00285 , A61B2018/00482 , A61B2018/00488 , A61B2018/00577 , A61B2018/046 , A61B2018/1495
摘要: An ablation device and methods for use thereof including a support structure adapted to support an ablation structure within an alimentary tract of a patient are provided. The support structure includes a longitudinal support with a longitudinal axis and a rotational support. The rotational support is adapted to permit at least part of the ablation structure to rotate with respect to the longitudinal support's longitudinal axis.
摘要翻译: 提供消融装置及其使用方法,其包括适于支撑患者消化道内的消融结构的支撑结构。 支撑结构包括具有纵向轴线和旋转支撑件的纵向支撑件。 旋转支撑件适于允许至少部分消融结构相对于纵向支撑件的纵向轴线旋转。
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公开(公告)号:US10278774B2
公开(公告)日:2019-05-07
申请号:US13051738
申请日:2011-03-18
IPC分类号: A61B18/12 , A61B18/14 , A61B18/00 , A61N7/02 , A61B18/06 , A61B18/08 , A61B18/24 , A61B18/02 , A61B18/18
摘要: In one embodiment, a device is provided including an expandable support member having a first portion and a second portion is provided. The first portion is adapted to have a smaller expansion index than the second portion. A therapeutic or diagnostic instrument is supported, at least in part, by the expandable support member first portion. In another embodiment, the support member is adapted for non-uniform expansion of the first and second portions. There are also described methods of forming therapeutic devices. There are also described methods of providing therapy to tissue in a body by positioning a device in proximity to tissue in a body selected to receive therapy. Next, the expandable support member second portion is expanded until the instrument is at a therapeutic position relative to the tissue in a body selected to receive therapy. Thereafter, therapy or diagnosis is provided to the selected tissue using the device.
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