公开(公告)号：US20240198101A1

公开(公告)日：2024-06-20

申请号：US18286987

申请日：2022-04-13

申请人： Gate Science, Inc.

发明人： Sanjay SINHA

IPC分类号： A61N1/36 ,  A61M5/142 ,  A61M25/00 ,  A61N1/05

CPC分类号： A61N1/36021 ,  A61M5/14244 ,  A61M25/0082 ,  A61N1/0551 ,  A61M2025/0095 ,  A61M2202/048 ,  A61M2205/04 ,  A61M2205/054 ,  A61M2210/1003 ,  A61N1/36034

摘要： Embodiments of the present disclosure relate to, among other things, systems, devices, and related methods for operating the same, to treat or provide pain control via multimodal control of pain. Specifically, embodiments of the present disclosure are directed to by both the delivery of pulsed electrical current to and/or around a nerve trunk, and delivery of one or more substances to and/or around the nerve trunk.

公开(公告)号：US20240189491A1

公开(公告)日：2024-06-13

申请号：US18584895

申请日：2024-02-22

申请人： Incept, LLC

发明人： Amarpreet S. Sawhney ,  Timothy S. Jarrett ,  Hans Claesson

IPC分类号： A61L33/00 ,  A61L33/08 ,  A61M25/09

CPC分类号： A61L33/0047 ,  A61L33/0064 ,  A61L33/08 ,  A61M25/09 ,  A61M2025/091 ,  A61M2202/0413 ,  A61M2202/0466 ,  A61M2210/083 ,  A61M2210/086 ,  A61M2210/1003 ,  A61M2210/12

摘要： Use of embolic material that is biodegradable provides for embolizing a hypervascular vessel formed in response to chronic inflammation in a musculoskeletal vasculature or a vessel related to production of ghrelin. The embolic material is biodegradable within a predetermined period of time. Medical systems are configured for delivery of embolic material for embolizing the hypervascular vessel or the vessel related to production of ghrelin.

公开(公告)号：US11992642B2

公开(公告)日：2024-05-28

申请号：US17085360

申请日：2020-10-30

申请人： Medtronic, Inc.

发明人： Jeffrey Bodner

IPC分类号： A61M39/02

CPC分类号： A61M39/0247 ,  A61M2039/027 ,  A61M2039/0273 ,  A61M2039/0276 ,  A61M2039/0282 ,  A61M2210/1003

摘要： An intrathecal drug delivery system includes: an intrathecal drug delivery device configured to deliver a fluid containing one or more pharmaceutical agents intrathecally to the cerebrospinal fluid (CSF) within a spinal canal of a patient and a deep brain catheter having an elongated body, extending from a distal end implanted within a deep brain structure of a patient and a proximal end positioned within the subarachnoid space directly adjacent to the brain to provide a passageway, via an inner lumen, between the subarachnoid space and the deep brain structure. The drug delivery system is configured to transport the pharmaceutical agent(s), using diffusion and the pulsatile flow of the CSF, through the deep brain catheter from the subarachnoid space to the deep brain structure.

公开(公告)号：US20230414656A1

公开(公告)日：2023-12-28

申请号：US17852139

申请日：2022-06-28

申请人： Panacea Spine, LLC

发明人： Ara Deukmedjian

IPC分类号： A61K33/38 ,  A61M13/00 ,  A61M29/00 ,  A61M5/32 ,  A61K9/00 ,  A61K9/16

CPC分类号： A61K33/38 ,  A61M13/00 ,  A61M29/00 ,  A61M5/329 ,  A61K9/0019 ,  A61K9/167 ,  A61M2210/1003 ,  A61M25/0105

摘要： A method for treating or repairing a damaged spinal disc of a patient may include inserting, using medical imaging, a shaft with a lumen extending from an exterior of a patient to the damaged spinal disc, dispensing silver particles, using the lumen, to the damaged spinal disc, and removing the hollow shaft from the patient. A system may include a syringe and silver particles in the syringe. A kit may include silver particles, and at least one of a guidewire, one or more dilators, a tubular retractor, a disposable endoscope, a disposable laser fiber; an endoscopic ronjeurs, indigo carmine dye, or a fluid adaptor.

公开(公告)号：US11850374B2

公开(公告)日：2023-12-26

申请号：US16896144

申请日：2020-06-08

申请人： ALCYONE THERAPEUTICS, INC.

发明人： P J Anand ,  Deep Arjun Singh ,  Jonathan Freund ,  Katelyn Perkins-Neaton ,  Thomas T. Washburn

IPC分类号： A61M25/00 ,  A61M5/172 ,  A61M5/145 ,  A61M5/00 ,  A61M5/168 ,  A61M25/10 ,  A61M39/02 ,  A61M5/19 ,  A61M25/01 ,  A61M25/09 ,  C12N15/113 ,  C12N15/11

CPC分类号： A61M25/003 ,  A61M5/007 ,  A61M5/14546 ,  A61M5/168 ,  A61M5/172 ,  A61M5/1723 ,  A61M25/0017 ,  A61M25/0032 ,  A61M25/0045 ,  A61M25/1002 ,  A61M25/1011 ,  A61M39/0208 ,  A61M5/19 ,  A61M25/0147 ,  A61M25/09 ,  A61M2005/1726 ,  A61M2025/0007 ,  A61M2025/1052 ,  A61M2205/0266 ,  A61M2205/3303 ,  A61M2205/3331 ,  A61M2205/3584 ,  A61M2205/502 ,  A61M2205/52 ,  A61M2210/0693 ,  A61M2210/1003 ,  A61M2230/06 ,  A61M2230/42 ,  C12N15/111 ,  C12N15/113 ,  C12N2310/11 ,  C12N2320/32 ,  C12N2320/35

摘要： A therapy specific, pre-programmed, hand-held auto-injection device for delivering a drug to a patient includes a housing, a plurality of syringes carried by the housing, at least one actuator disposed within the housing coupled to the plurality of syringes, and a controller disposed within the housing and communicatively coupled to the at least one actuator. The controller is configured to receive an infusion and aspiration profile, which includes an infusion and aspiration protocol for controlling at least one of the plurality of syringes. The controller is also configured to operate the at least one actuator based on the infusion and aspiration protocol by either expelling a fluid from a respective barrel of the plurality of syringes into the infusion and aspiration location or drawing a fluid from the infusion and aspiration location into a respectively barrel of the plurality of syringes.

公开(公告)号：US11806069B2

公开(公告)日：2023-11-07

申请号：US16257905

申请日：2019-01-25

申请人： Warsaw Orthopedic, Inc.

发明人： Jared Wilsey

IPC分类号： A61B18/14 ,  A61B17/32 ,  A61N1/05 ,  A61B18/20 ,  A61B18/00

CPC分类号： A61B18/1477 ,  A61B17/320068 ,  A61B18/20 ,  A61N1/0551 ,  A61B2018/0044 ,  A61M2210/1003

摘要： A device is provided for supplying electrical current to an intervertebral disc. The device comprises a cannula having a proximal end and a distal end and a longitudinal axis therebetween. The distal end comprises a beveled tip for contacting a region of the intervertebral disc, and an electrode disposed within or on a surface of the cannula adjacent to the distal end. The electrode is configured to discharge electrical current to the region of the intervertebral disc. Methods of diagnosing and/or treating discogenic back pain are also provided.

公开(公告)号：US09918709B2

公开(公告)日：2018-03-20

申请号：US15235765

申请日：2016-08-12

申请人： Spinal USA, Inc.

发明人： Faheem A. Sandhu

IPC分类号： A61B17/02 ,  A61B1/07 ,  A61B1/32 ,  A61B17/34 ,  A61M29/00 ,  A61B17/00

CPC分类号： A61B17/0218 ,  A61B1/07 ,  A61B1/32 ,  A61B17/02 ,  A61B17/025 ,  A61B17/3423 ,  A61B2017/0046 ,  A61B2017/0256 ,  A61M29/00 ,  A61M2210/1003

摘要： A retractor assembly for defining a working channel to a surgical site for conducting minimally invasive spinal surgery includes a plurality of relatively articulable components. Temporary interconnections are formed between adjacent sidewalls of the components to hold the components in a de sired configuration, such as in a closed triangular form. The components are articulable relative to each other for adjusting the working channel or for performing surgical functions.

公开(公告)号：US09895518B2

公开(公告)日：2018-02-20

申请号：US13801215

申请日：2013-03-13

申请人： Neurofluidics, Inc.

发明人： Shivanand Lad ,  William C. Mobley ,  Karoly Nikolich ,  Thomas Saul

IPC分类号： A61M1/00 ,  A61M27/00 ,  A61M1/36

CPC分类号： A61M27/006 ,  A61M1/3679 ,  A61M25/0026 ,  A61M2025/0007 ,  A61M2027/004 ,  A61M2202/0021 ,  A61M2202/0464 ,  A61M2202/203 ,  A61M2202/206 ,  A61M2206/16 ,  A61M2210/0693 ,  A61M2210/1003

摘要： The present invention provides methods and systems for conditioning cerebrospinal fluid (CSF) by removing target compounds from CSF. The systems provide for a multilumen flow path and exchange of a majority volume portion of CSF in the CSF space. The removal and/or delivery of specific compounds can be tailored to the pathology of the specific disease. The removal is targeted and specific, for example, through the use of specific size-exclusion thresholds, antibodies against specific toxins, and other chromatographic techniques, as well as delivery and/or removal of targeted therapeutic agents.

公开(公告)号：US20170368242A1

公开(公告)日：2017-12-28

申请号：US15700667

申请日：2017-09-11

申请人： Wake Forest University Health Sciences

发明人： Louis C. Argenta ,  David L. Carroll ,  Nicole H. Levi ,  Jie Liu ,  Michael J. Morykwas ,  Stephen Tatter ,  William D. Wagner

IPC分类号： A61M1/00 ,  A61F13/00

CPC分类号： A61M1/0088 ,  A61F13/00021 ,  A61M1/0023 ,  A61M2210/1003

摘要： The present invention provides devices and methods that treat damaged spinal cord tissue, such as spinal tissue damaged by disease, infection, or trauma, which may lead to the presence of swelling, compression, and compromised blood flow secondary to interstitial edema.

公开(公告)号：US09814857B2

公开(公告)日：2017-11-14

申请号：US15002481

申请日：2016-01-21

申请人： Avent, Inc.

发明人： Michael F. Guzman

IPC分类号： A61M19/00 ,  A61B46/00 ,  A61M5/42 ,  A61M25/06 ,  A61B1/313 ,  A61M5/142 ,  A61B46/20 ,  A61M5/46 ,  A61M5/158 ,  A61M5/172 ,  A61M25/00 ,  A61B17/34 ,  A61B5/11 ,  A61B5/00 ,  A61B8/08 ,  A61M29/00

CPC分类号： A61M19/00 ,  A61B1/3132 ,  A61B5/1106 ,  A61B5/4821 ,  A61B8/0841 ,  A61B17/3401 ,  A61B17/3403 ,  A61B46/00 ,  A61B46/20 ,  A61M5/142 ,  A61M5/158 ,  A61M5/1723 ,  A61M5/42 ,  A61M5/427 ,  A61M5/46 ,  A61M25/06 ,  A61M25/065 ,  A61M25/0662 ,  A61M25/0668 ,  A61M29/00 ,  A61M2005/1726 ,  A61M2025/0007 ,  A61M2025/0681 ,  A61M2210/1003 ,  A61M2210/1017 ,  A61M2210/1021 ,  Y10S514/818

摘要： Apparatus for administering certain nerve blocks includes a sheath constructed from a flexible ultrasound echogenic material, a more rigid introducer/dilator for introducing the sheath into the patient, and an ultrasound echogenic catheter for inserting through the sheath once the distal end of the sheath is in place adjacent the nerve(s) to be blocked and the introducer/dilator has been withdrawn. The catheter has provisions at its proximal end for connecting to a source of local anesthetic. Methods for use of this apparatus are also described.