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    Method of forming intra-aortic balloon catheters
    1.
    发明授权
    Method of forming intra-aortic balloon catheters 失效
    形成主动脉内气囊导管的方法

    公开(公告)号：US5718861A

    公开(公告)日：1998-02-17

    申请号：US484894

    申请日：1995-06-07

    申请人： Robert R. Andrews ,  William Edelman ,  Joseph A. Levendusky ,  Peter T. Majeski ,  Robert L. O'Brien

    发明人： Robert R. Andrews ,  William Edelman ,  Joseph A. Levendusky ,  Peter T. Majeski ,  Robert L. O'Brien

    IPC分类号： A61F2/958 ,  A61M1/10 ,  A61M25/00 ,  B29C41/14 ,  B29C55/22 ,  B29C71/02

    CPC分类号： B29C55/22 ,  A61M1/1072 ,  A61M25/1029 ,  A61M25/1034 ,  B29C41/14 ,  A61M25/0045 ,  A61M25/10 ,  B29L2031/7542

    摘要： A method of forming intra-aortic balloons includes forming a balloon blank having a sleeve section at its proximal end. To reduce the diameter of the sleeve section of the balloon, the sleeve section is stretched longitudinally by gripping a first portion of the balloon blank at the distal end of the sleeve section, gripping a second portion of the balloon blank at the opposite end of the sleeve section and moving at least one of the gripped portions away from the other so as to reduce the diameter of the sleeve section. A heating element is positioned within the sleeve section to relieve the stress in the sleeve after stretching, by heating the sleeve section. The sleeve section is then cooled in order to preserve the sleeve section in its reduced diameter state thereby forming an intra-aortic balloon having a balloon blank with a reduced diameter sleeve section.

    摘要翻译： 形成主动脉内球囊的方法包括在其近端形成具有套筒部分的球囊坯料。 为了减小气囊的套筒部分的直径，通过在套筒部分的远端处抓住球囊坯料的第一部分来纵向地拉伸套管部分，在该套筒部分的相对端处抓住气球坯料的第二部分 套筒部分，并且将夹持部分中的至少一个远离另一个移动，以减小套筒部分的直径。 加热元件定位在套筒部分内，以通过加热套筒部分来拉伸拉伸后的套筒中的应力。 然后将套筒部分冷却以便将套管部分保持在其缩径状态，从而形成具有直径减小的套管部分的球囊坯料的主动脉内球囊。

    Intra-aortic balloon catheters
    2.
    发明授权
    Intra-aortic balloon catheters 失效
    主动脉内气囊导管

    公开(公告)号：US5865721A

    公开(公告)日：1999-02-02

    申请号：US658386

    申请日：1996-06-05

    申请人： Robert R. Andrews ,  William Edelman ,  Joseph A. Levendusky ,  Robert L. O'Brien

    发明人： Robert R. Andrews ,  William Edelman ,  Joseph A. Levendusky ,  Robert L. O'Brien

    IPC分类号： A61F2/958 ,  A61M1/10 ,  A61M25/00 ,  B29C41/14 ,  B29C55/22 ,  A61N1/362

    CPC分类号： B29C55/22 ,  A61M1/1072 ,  A61M25/1029 ,  A61M25/1034 ,  B29C41/14 ,  A61M25/0045 ,  A61M25/10 ,  B29L2031/7542

    摘要： An intra-aortic balloon pump catheter includes an inner lumen formed by a thin walled superelastic metal alloy tube, namely of nitinol, with an inside diameter sufficient for a guidewire and a small outside diameter which allows reduction of the outer lumen and related components by at least one size French while providing gas shuttle capacity between the lumens for conventional intra-aortic balloon pump operation. The outer lumen is a tube formed of co-extruded plastics to enhance the size reduction and capacity goals, with an inner nylon portion for strength and a relatively thin polyurethane outer portion for biocompatability, flexibility and compatibility for bonding to a thin polyurethane balloon. The proximal end sleeve of the balloon is stretched and then stress-relieved by heating with an internal heater on a mounting mandrel to effect a desired small diameter sizing. A radiopaque metal marker ring of nitinol also is provided to improve imaging capabilities while being compatible with the lumen materials.

    摘要翻译： 主动脉内球囊泵导管包括由薄壁超弹性金属合金管（即镍钛诺）形成的内腔，其具有足以用于导丝的内径和小的外径，其允许通过以下方式减少外腔和相关部件 至少一个尺寸的法国​​人，同时在传统的主动脉内球囊泵操作的腔之间提供气体穿梭能力。 外腔是由共挤塑料形成的管，以增强尺寸减小和容量目标，其具有用于强度的内部尼龙部分和用于生物相容性的相对薄的聚氨酯外部部分，用于粘合到薄的聚氨酯气球的柔性和相容性。 气囊的近端套筒被拉伸，然后通过用安装心轴上的内部加热器加热来减轻应力，以实现所需的小直径尺寸。 还提供镍钛诺的不透射线的金属标记环以提高成像能力，同时与管腔材料相容。

    Method for making a packaging sheath for intra-aortic balloon catheters
    3.
    发明授权
    Method for making a packaging sheath for intra-aortic balloon catheters 失效
    用于制作主动脉内气囊导管的包装护套的方法

    公开(公告)号：US5935501A

    公开(公告)日：1999-08-10

    申请号：US483923

    申请日：1995-06-07

    申请人： Robert R. Andrews ,  William Edelman ,  Ilyssa A. Hunt

    发明人： Robert R. Andrews ,  William Edelman ,  Ilyssa A. Hunt

    IPC分类号： A61B17/00 ,  A61M25/00 ,  B29C33/12 ,  B29C45/14

    CPC分类号： A61M25/002

    摘要： An intra-aortic balloon packaging sheath is provided which includes a long slim extruded plastic tube for storing a furled thin-walled intra-aortic balloon. An entry section of the same plastic is injection molded onto one end of the tube, with the entry section including an outwardly flared entry port surface which is spaced from one end of the tube, and an internal passageway which is co-linear and congruent with the internal cross-section of the tube from the respective end of the tube through the intersection of the second internal passageway with the outwardly flared passageway. Thereby a smooth internal surface is provided through the flared passageway into the internal passageway and through the later into the tube. The exit end of the sheath tube is inverted by use of a heated tipping die such that a distal end portion is turned outwardly and back circumjacent another portion of the tube wall to form a smoothly rounded exit passageway of the tube at the exit end.

    摘要翻译： 提供了一种主动脉内气囊包装护套，其包括用于储存卷曲的薄壁主动脉内球囊的长纤维挤出塑料管。 相同塑料的入口部分注射成型到管的一端，入口部分包括与管的一端间隔开的向外扩张的入口表面，以及内部通道，其与 管的相应端部的管的内部横截面通过第二内部通道与向外扩张的通道的相交。 因此，通过扩口通道提供平滑的内表面进入内部通道并且通过稍后进入管中。 护套管的出口端通过使用加热的接头模具反转，使得远端部分向外转动并且绕管壁的另一部分返回，以在出口端处形成光滑的圆形出口通道。

    Packaging sheaths for intra-aortic balloon catheters
    4.
    发明授权
    Packaging sheaths for intra-aortic balloon catheters 失效
    用于主动脉内气囊导管的包装护套

    公开(公告)号：US5524757A

    公开(公告)日：1996-06-11

    申请号：US210551

    申请日：1994-03-18

    申请人： Robert R. Andrews ,  William Edelman ,  Ilyssa A. Hunt

    发明人： Robert R. Andrews ,  William Edelman ,  Ilyssa A. Hunt

    IPC分类号： A61B17/00 ,  A61M25/00 ,  B65D81/18

    CPC分类号： A61M25/002

    摘要： An intra-aortic balloon packaging sheath is provided which includes a long slim extruded plastic tube for storing a furled thin-walled intra-aortic balloon. An entry section of the same plastic is injection molded onto one end of the tube, with the entry section including an outwardly flared entry port surface which is spaced from one end of the tube, and an internal passageway which is co-linear and congruent with the internal cross-section of the tube from the respective end of the tube through the intersection of the second internal passageway with the outwardly flared passageway. Thereby a smooth internal surface is provided through the flared passageway into the internal passageway and through the later into the tube. The exit end of the sheath tube is inverted by use of a heated tipping die such that a distal end portion is turned outwardly and back circumjacent another portion of the tube wall to form a smoothly rounded exit passageway of the tube at the exit end.

    摘要翻译： 提供了一种主动脉内气囊包装护套，其包括用于储存卷曲的薄壁主动脉内球囊的长纤维挤出塑料管。 相同塑料的入口部分注射成型到管的一端，入口部分包括与管的一端间隔开的向外扩张的入口表面，以及内部通道，其与 管的相应端部的管的内部横截面通过第二内部通道与向外扩张的通道的相交。 因此，通过扩口通道提供平滑的内表面进入内部通道并且通过稍后进入管中。 护套管的出口端通过使用加热的接头模具反转，使得远端部分向外转动并且绕管壁的另一部分返回，以在出口端处形成光滑的圆形出口通道。

    Mesh Pouches for Implantable Medical Devices
    8.
    发明申请
    Mesh Pouches for Implantable Medical Devices 有权
    用于植入式医疗器械的网袋

    公开(公告)号：US20080132922A1

    公开(公告)日：2008-06-05

    申请号：US11936054

    申请日：2007-11-06

    申请人： Fatima Buevich ,  Frank Do ,  William McJames ,  Satish Pulapura ,  William Edelman ,  Arikha Moses ,  Mason Diamond ,  Shari Timothy

    发明人： Fatima Buevich ,  Frank Do ,  William McJames ,  Satish Pulapura ,  William Edelman ,  Arikha Moses ,  Mason Diamond ,  Shari Timothy

    IPC分类号： A61B17/08 ,  B65D69/00

    CPC分类号： A61L31/10 ,  A61B2017/00889 ,  A61B2017/00893 ,  A61B2090/0815 ,  A61L31/146 ,  A61L31/148 ,  A61L31/16 ,  A61L2300/00 ,  A61N1/375

    摘要： Biodegradable polymer-coated surgical meshes formed into pouches are described for use with cardiac rhythm management devices (CRMs) and other implantable medical devices. Such meshes are formed into a receptacle, e.g., a pouch or other covering, capable of encasing, surrounding and/or holding the cardiac rhythm management device or other implantable medical device for the purpose of securing it in position, inhibiting or reducing bacterial growth, providing pain relief and/or inhibiting scarring or fibrosis on or around the CRM or other implantable medical device. Preferred embodiments include surgical mesh pouches coated with one or more biodegradable polymers that can act as a stiffening agent by coating the filaments or fibers of the mesh to temporarily immobilize the contact points of those filaments or fibers and/or by increasing the stiffness of the mesh by at least 1.1 times its original stiffness. The pouches of the invention can also provide relief from various post-operative complications associated with their implantation, insertion or surgical use, and, optionally, include one or more drugs in the polymer matrix of the coating to provide prophylactic effects and/or alleviate side effects or complications associated with the surgery or implantation of the CRM or other implantable medical device.

    摘要翻译： 描述形成袋的可生物降解的聚合物涂覆的手术网与心律管理装置（CRM）和其他可植入医疗装置一起使用。 这样的网状物形成为能够包围，围绕和/或保持心律管理装置或其它可植入医疗装置的容器，例如袋或其它覆盖物，以确保其在适当位置，抑制或减少细菌生长， 在CRM或其他可植入医疗设备上或周围提供疼痛缓解和/或抑制瘢痕形成或纤维化。 优选的实施方案包括涂覆有一种或多种可生物降解的聚合物的手术网袋，其可以通过涂覆网的细丝或纤维来暂时固定那些丝或纤维的接触点和/或通过增加网的刚度而充当硬化剂 至少是其原始刚度的1.1倍。 本发明的小袋还可以缓解与其植入，插入或手术使用相关的各种术后并发症，并且任选地在包衣的聚合物基质中包括一种或多种药物以提供预防效果和/或缓解侧 与手术或植入CRM或其他可植入医疗器械相关的影响或并发症。