公开(公告)号：US06319410B1

公开(公告)日：2001-11-20

申请号：US09521630

申请日：2000-03-08

申请人： Robert William Allington ,  Daniel Gene Jameson ,  Dale A. Davison ,  Dale Clay ,  Robin R. Winter ,  Yoossef Tehrani

发明人： Robert William Allington ,  Daniel Gene Jameson ,  Dale A. Davison ,  Dale Clay ,  Robin R. Winter ,  Yoossef Tehrani

IPC分类号： B01D1100

CPC分类号： G01N1/34 ,  B01D11/0203 ,  B01D11/0407 ,  F04B9/042 ,  F04B15/08 ,  F04B49/065 ,  F04B53/08 ,  F04B53/143 ,  F04B2201/0209 ,  F04B2205/03 ,  F04B2205/05 ,  F04B2205/09 ,  F05B2230/41 ,  F05C2201/0493 ,  F05C2253/12 ,  F16K15/183 ,  G01F1/34 ,  G01N1/40 ,  G01N30/02 ,  G01N30/28 ,  G01N2001/4033 ,  G01N2001/4061 ,  G01N2030/6013 ,  G01N2035/0441 ,  G21F5/015 ,  B01D15/40

摘要： To provide performance particularly in handling supercritical extraction systems, a specially designed pump includes a cam-driven, single-plunger with a cam having a profile that enables the pumping system to avoid destructive reverse torque on the cam, gear train and drive motor after the cam passes top dead center. The plunger includes a seal having one side in contact with the supercritical fluid and a mechanism for supporting and aligning the piston on the other side of the seal to maintain the piston in alignment. The piston drive has Hertzian contact with the piston. The fluid volume leaving the pump is determined by measuring only pressure or other parameters related to flow and movement of the plunger. Measurement of the fluid volume leaving the pump is useful for recording or indicating the flow rate while the pump is operating.

摘要翻译： 为了提供特别在处理超临界萃取系统中的性能，专门设计的泵包括凸轮驱动的单柱塞，其具有凸轮，该凸轮具有轮廓，使得泵系统能够避免在凸轮，齿轮系和驱动马达之后的破坏性反向扭矩 凸轮通过上死点。 柱塞包括具有与超临界流体接触的一侧的密封件和用于在密封件的另一侧支撑和对准活塞以使活塞保持对准的机构。 活塞驱动器与活塞接触Hertzian。 通过仅测量与柱塞的流动和运动相关的压力或其它参数来确定离开泵的流体体积。 离开泵的流体体积的测量对于在泵运行时记录或指示流量是有用的。

公开(公告)号：US6071408A

公开(公告)日：2000-06-06

申请号：US80826

申请日：1998-05-18

申请人： Robert William Allington ,  Daniel Gene Jameson ,  Dale A. Davison ,  Dale Clay ,  Robin R. Winter ,  Yoossef Tehrani

发明人： Robert William Allington ,  Daniel Gene Jameson ,  Dale A. Davison ,  Dale Clay ,  Robin R. Winter ,  Yoossef Tehrani

IPC分类号： B01D11/00 ,  B01D11/02 ,  B01D11/04 ,  F04B9/04 ,  F04B15/08 ,  F04B49/06 ,  F04B53/08 ,  F04B53/14 ,  F16K15/18 ,  G01F1/34 ,  G01N1/34 ,  G01N1/40 ,  G01N30/02 ,  G01N30/28 ,  G01N30/60 ,  G01N35/04 ,  G21F5/015 ,  B01D17/12

CPC分类号： G01N1/34 ,  B01D11/0203 ,  B01D11/0407 ,  F04B15/08 ,  F04B49/065 ,  F04B53/08 ,  F04B53/143 ,  F04B9/042 ,  F16K15/183 ,  G01F1/34 ,  G01N1/40 ,  G01N30/28 ,  G21F5/015 ,  F04B2201/0209 ,  F04B2205/03 ,  F04B2205/05 ,  F04B2205/09 ,  F05B2230/41 ,  F05C2201/0493 ,  F05C2253/12 ,  G01N2001/4033 ,  G01N2001/4061 ,  G01N2030/6013 ,  G01N2035/0441 ,  G01N30/02

摘要： To provide performance particularly in handling supercritical extraction systems, a specially designed pump includes a cam-driven, single-plunger with a cam having a profile that enables the pumping system to avoid destructive reverse torque on the cam, gear train and drive motor after the cam passes top dead center. The fluid volume leaving the pump is determined by measuring only pressure or other parameters related to flow and movement of the plunger. Measurement of the fluid volume leaving the pump is useful for recording or indicating the flow rate while the pump is operating.

摘要翻译： 为了提供特别在处理超临界萃取系统中的性能，专门设计的泵包括凸轮驱动的单柱塞，其具有凸轮，该凸轮具有轮廓，使得泵系统能够避免在凸轮，齿轮系和驱动马达之后的破坏性反向扭矩 凸轮通过上死点。 通过仅测量与柱塞的流动和运动相关的压力或其它参数来确定离开泵的流体体积。 离开泵的流体体积的测量对于在泵运行时记录或指示流量是有用的。

公开(公告)号：US5738498A

公开(公告)日：1998-04-14

申请号：US673202

申请日：1996-06-27

申请人： Robert William Allington ,  Daniel Gene Jameson ,  Dale A. Davison ,  Dale Clay ,  Robin R. Winter ,  Yoossef Tehrani

发明人： Robert William Allington ,  Daniel Gene Jameson ,  Dale A. Davison ,  Dale Clay ,  Robin R. Winter ,  Yoossef Tehrani

IPC分类号： B01D11/00 ,  B01D11/02 ,  B01D11/04 ,  F04B9/04 ,  F04B15/08 ,  F04B49/06 ,  F04B53/08 ,  F04B53/14 ,  F16K15/18 ,  G01F1/34 ,  G01N1/34 ,  G01N1/40 ,  G01N30/02 ,  G01N30/28 ,  G01N30/60 ,  G01N35/04 ,  G21F5/015 ,  F04B39/06 ,  F25B21/02

CPC分类号： G01N1/34 ,  B01D11/0203 ,  B01D11/0407 ,  F04B15/08 ,  F04B49/065 ,  F04B53/08 ,  F04B53/143 ,  F04B9/042 ,  F16K15/183 ,  G01F1/34 ,  G01N1/40 ,  G01N30/28 ,  G21F5/015 ,  F04B2201/0209 ,  F04B2205/03 ,  F04B2205/05 ,  F04B2205/09 ,  F05B2230/41 ,  F05C2201/0493 ,  F05C2253/12 ,  G01N2001/4033 ,  G01N2001/4061 ,  G01N2030/6013 ,  G01N2035/0441 ,  G01N30/02

摘要： In a piston pump for pumping liquid carbon dioxide at a temperature below 30 degrees Fahrenheit and pressures at least as high as 7500 psi at an outlet flow rate in excess of 10 milliliters per minute, the inlet to the pump and the pumphead are each cooled by thermoelectric heat exchangers that are air cooled. The pump is a cam-driven, single-plunger pump with a cam profile that enables the pumping system to avoid distructive reverse torque on the cam, gear train and drive motor after the cam passes top dead center. The volume leaving the pump is determined by measuring only pressure or other parameter related to flow and movement of the plunger. The piston of the pump is supported on both sides of the seal and the support for the piston within the pumphead are machined consentrically and colinearly to the seal gland.

摘要翻译： 在用于在低于30华氏度的温度下泵送液体二氧化碳的活塞泵和在超过10毫升/分钟的出口流速下至少高达7500psi的压力下，泵和泵头的入口各自被 空气冷却的热电换热器。 泵是具有凸轮轮廓的凸轮驱动的单柱塞泵，其能够使泵送系统在凸轮通过上止点之后避免凸轮，齿轮系和驱动马达上的破坏性反向扭矩。 通过仅测量与柱塞的流动和运动相关的压力或其他参数来确定离开泵的体积。 泵的活塞支撑在密封件的两侧，并且泵头内的活塞支撑件同步地并且与密封压盖共同加工。

公开(公告)号：US5755559A

公开(公告)日：1998-05-26

申请号：US673177

申请日：1996-06-26

申请人： Robert William Allington ,  Daniel Gene Jameson ,  Dale A. Davison ,  Dale Clay ,  Robin R. Winter ,  Yoossef Tehrani

发明人： Robert William Allington ,  Daniel Gene Jameson ,  Dale A. Davison ,  Dale Clay ,  Robin R. Winter ,  Yoossef Tehrani

IPC分类号： B01D11/00 ,  B01D11/02 ,  B01D11/04 ,  F04B9/04 ,  F04B15/08 ,  F04B49/06 ,  F04B53/08 ,  F04B53/14 ,  F16K15/18 ,  G01F1/34 ,  G01N1/34 ,  G01N1/40 ,  G01N30/02 ,  G01N30/28 ,  G01N30/60 ,  G01N35/04 ,  G21F5/015 ,  F04B49/00

CPC分类号： G01N1/34 ,  B01D11/0203 ,  B01D11/0407 ,  F04B15/08 ,  F04B49/065 ,  F04B53/08 ,  F04B53/143 ,  F04B9/042 ,  F16K15/183 ,  G01F1/34 ,  G01N1/40 ,  G01N30/28 ,  G21F5/015 ,  F04B2201/0209 ,  F04B2205/03 ,  F04B2205/05 ,  F04B2205/09 ,  F05B2230/41 ,  F05C2201/0493 ,  F05C2253/12 ,  G01N2001/4033 ,  G01N2001/4061 ,  G01N2030/6013 ,  G01N2035/0441 ,  G01N30/02

摘要： In a piston pump for pumping liquid carbon dioxide at a temperature below 30 degrees Fahrenheit and pressures at least as high as 7500 psi, the volume leaving the pump is determined by measuring only pressure or other parameter related to flow and movement of the plunger. The position of the piston is measured and the resulting displacement is integrated to determine volume of fluid pumped.

摘要翻译： 在用于在低于30华氏度的温度下泵送液体二氧化碳和至少高达7500psi的压力的活塞泵中，通过仅测量与柱塞的流动和运动相关的压力或其它参数来确定离开泵的体积。 测量活塞的位置，并将所得到的位移整合在一起，以确定泵送的流体体积。

公开(公告)号：US6086767A

公开(公告)日：2000-07-11

申请号：US879395

申请日：1997-06-20

申请人： Henry LeRoy Walters ,  Robert William Allington ,  Daniel Gene Jameson ,  Yoossef Tehrani

发明人： Henry LeRoy Walters ,  Robert William Allington ,  Daniel Gene Jameson ,  Yoossef Tehrani

IPC分类号： B01D11/02 ,  B01D11/04 ,  F04B9/04 ,  F04B15/08 ,  F04B49/06 ,  F16K15/18 ,  G01F1/34 ,  G01N1/34 ,  G01N1/40 ,  G01N30/02 ,  G01N30/28 ,  G01N30/32 ,  G01N30/60 ,  G01N30/82 ,  G01N35/04 ,  G21F5/015 ,  B01D15/08

CPC分类号： B01D11/0203 ,  B01D11/0407 ,  F04B15/08 ,  F04B49/065 ,  F04B9/042 ,  F16K15/183 ,  G01F1/34 ,  G01N1/34 ,  G01N1/40 ,  G01N30/28 ,  G01N30/82 ,  G21F5/015 ,  F04B2205/03 ,  F04B2205/05 ,  F04B2205/09 ,  F05B2230/41 ,  F05C2201/0493 ,  F05C2253/12 ,  G01N2001/4033 ,  G01N2001/4061 ,  G01N2030/6008 ,  G01N2030/6013 ,  G01N2035/0441 ,  G01N30/02 ,  G01N30/32 ,  G01N30/60

摘要： An automatic variable-orifice fluid restrictor for use with a supercritical extractor having a collection trap or a supercritical chromatograph includes an inlet line for fluid at a pressure above its critical pressure, an extended tubular probe having an inner and an outer surface and a proximal and a distal end. The proximal end of the probe carries an inlet connected to the inlet line and is outside of the trap. The distal end of the probe includes a variable orifice means adapted for metering the fluid. The variable orifice means is adjacent to the outer surface of the probe and is located in the midst of the trap. The variable orifice means is adjusted by an adjusting stem having first and second ends. The first end of the adjusting stem is connected to automatic control means such as a servo at the proximal end of the probe and outside of the trap. The second end of the adjusting stem varies the area of the orifice by moving a first orifice member. The stationary second orifice member cooperates with the first orifice member to form the orifice. The first orifice member moves axially when the orifice is closed and moves both axially and rotationally when the orifice is open or partially open. This cleans deposits from the orifice without damaging the orifice parts by high pressure notional physical contact.

摘要翻译： 用于具有收集阱或超临界色谱仪的超临界萃取器的自动可变孔流体限制器包括用于高于其临界压力的压力的流体的入口管线，具有内表面和外表面的延伸管状探针， 一个远端 探针的近端带有连接到入口管线并且位于捕集器外部的入口。 探针的远端包括适于计量流体的可变孔口装置。 可变孔口装置邻近探针的外表面并且位于捕获器的中间。 可变孔装置由具有第一和第二端的调节杆调节。 调节杆的第一端连接到自动控制装置，例如在探头的近端处的伺服机构和陷阱的外部。 调节杆的第二端通过移动第一孔口部件来改变孔口的面积。 固定的第二孔口构件与第一孔口构件协作以形成孔口。 当孔口关闭时，第一孔口部件轴向移动，当孔口打开或部分打开时，第一孔口部件轴向和旋转地移动。 这样可以从孔中清除沉积物，而不会通过高压物理接触而损坏孔口部件。

公开(公告)号：US06251267B1

公开(公告)日：2001-06-26

申请号：US08215259

申请日：1994-03-21

申请人： Robert William Allington ,  Daniel Gene Jameson ,  Robin Randall Winter ,  Dale Lee Clay

发明人： Robert William Allington ,  Daniel Gene Jameson ,  Robin Randall Winter ,  Dale Lee Clay

IPC分类号： B01D1100

CPC分类号： B01D11/0203 ,  B01D11/0407 ,  F04B9/042 ,  F04B15/08 ,  F04B49/065 ,  F04B2205/03 ,  F04B2205/05 ,  F04B2205/09 ,  F05B2230/41 ,  F05C2201/0493 ,  F05C2253/12 ,  F16K15/183 ,  G01F1/34 ,  G01N1/34 ,  G01N1/40 ,  G01N30/02 ,  G01N30/28 ,  G01N2001/4033 ,  G01N2001/4061 ,  G01N2030/6013 ,  G01N2035/0441 ,  G21F5/015 ,  B01D15/40

摘要： An apparatus for supercritical extraction is disclosed herein. The apparatus includes a plurality of containers adapted to hold a different one of a corresponding plurality of samples, a first transport means for carrying the plurality of sample containers, and a second transport means for transporting a selected container from the first transport means to a supercritical extractor. The supercritical extractor includes a heating means having a recess for receiving the selected container, means for passing fluid at a supercritical condition through the selected container, and a receiving means for receiving extractant from the selected container. A programming means is provided to control the first and second transport means.

摘要翻译： 本文公开了一种超临界萃取装置。 该装置包括适于容纳相应多个样品中不同的一个样本的多个容器，用于承载多个样品容器的第一传送装置和用于将选定的容器从第一传送装置运送到超临界的第二传送装置 提取器。 超临界提取器包括具有用于接收所选择的容器的凹部的加热装置，用于使超临界状态的流体通过所选择的容器的装置，以及用于从所选容器接收萃取剂的接收装置。 提供编程装置来控制第一和第二传送装置。

公开(公告)号：US5690828A

公开(公告)日：1997-11-25

申请号：US601250

申请日：1996-02-14

申请人： Dale Lee Clay ,  Robert William Allington ,  Phillip Bearnard Liescheski, III ,  Robin Randall Winter ,  Daniel Gene Jameson

发明人： Dale Lee Clay ,  Robert William Allington ,  Phillip Bearnard Liescheski, III ,  Robin Randall Winter ,  Daniel Gene Jameson

IPC分类号： B01D11/02 ,  B01D11/04 ,  F04B9/04 ,  F04B15/08 ,  F04B49/06 ,  F16K15/18 ,  G01F1/34 ,  G01N1/34 ,  G01N1/40 ,  G01N30/02 ,  G01N30/28 ,  G01N30/60 ,  G01N35/04 ,  G21F5/015 ,  B01D11/00 ,  B01D17/12

CPC分类号： B01D11/0203 ,  B01D11/0407 ,  F04B15/08 ,  F04B49/065 ,  F04B9/042 ,  F16K15/183 ,  G01F1/34 ,  G01N1/34 ,  G01N1/40 ,  G01N30/28 ,  G21F5/015 ,  F04B2205/03 ,  F04B2205/05 ,  F04B2205/09 ,  F05B2230/41 ,  F05C2201/0493 ,  F05C2253/12 ,  G01N2001/4033 ,  G01N2001/4061 ,  G01N2030/6013 ,  G01N2035/0441 ,  G01N30/02

摘要： To supply supercritical fluid to an automatic supercritical fluid extractor and collect extract from the extractor, sample holding cartridges are lifted one by one in series by an elevator plug into a pressure chamber. An inlet at the top of the cartridge engages a pressure vessel inlet for the extractant so that extractant flows into the cartridge and into the space between the cartridge and inner walls of the pressure chamber. The outlets from the cartridge and pressure vessel communicate with the collector and exhaust through passageways in the plug. The plug has cleaning ports for cleaning seals and the outlet from the cartridge flows past the seals. The collector lifts vials into place and can precool the collection solvent, and later as part of the collection procedure, heat and pressurize the collector.

摘要翻译： 为了将超临界流体提供给自动超临界流体提取器并从提取器收集提取物，样品保持盒由电梯塞一个接一个地提升到压力室中。 药筒顶部的入口接合用于提取剂的压力容器入口，使得萃取剂流入药筒并进入药筒和压力室的内壁之间的空间。 墨盒和压力容器的出口与收集器连通，并通过插头中的通道排出。 插头具有用于清洁密封件的清洁端口，并且墨盒的出口流过密封件。 收集器将小瓶提升到适当位置，并可预先收集溶剂，然后作为收集过程的一部分，对收集器进行加热和加压。

公开(公告)号：US5653885A

公开(公告)日：1997-08-05

申请号：US579644

申请日：1995-12-27

申请人： Daniel Gene Jameson ,  Robert Joseph Macomber ,  Robert William Allington

发明人： Daniel Gene Jameson ,  Robert Joseph Macomber ,  Robert William Allington

IPC分类号： B01D11/02 ,  B01D11/04 ,  F04B9/04 ,  F04B15/08 ,  F04B49/06 ,  F04B53/08 ,  F04B53/14 ,  F16K15/18 ,  G01F1/34 ,  G01N1/34 ,  G01N1/40 ,  G01N30/02 ,  G01N30/28 ,  G01N30/60 ,  G01N35/04 ,  G21F5/015 ,  B01D11/00 ,  B01D15/08

CPC分类号： G21F5/015 ,  B01D11/0203 ,  B01D11/0407 ,  F04B15/08 ,  F04B49/065 ,  F04B53/08 ,  F04B53/143 ,  F04B9/042 ,  F16K15/183 ,  G01F1/34 ,  G01N1/34 ,  G01N1/40 ,  G01N30/28 ,  F04B2201/0209 ,  F04B2205/03 ,  F04B2205/05 ,  F04B2205/09 ,  F05B2230/41 ,  F05C2201/0493 ,  F05C2253/12 ,  G01N2001/4033 ,  G01N2001/4061 ,  G01N2030/6013 ,  G01N2035/0441 ,  G01N30/02

摘要： To avoid deposits on the restrictor that channels extractant into a collector, a heated capillary tube pressure release restrictor, has a thermally insulated outlet end in a collecting trap substantially colder than the capillary tube. The restrictor is heated between the insulation and the capillary tube by Joulean heating. The solvent in the trap is at a pressure of 5 to 200 psi above atmospheric pressure. The thermal resistance of the insulation is selected to reduce the heat added to the extractant to a minimum and yet cause the temperature of the extractant to be in a range within which it is sufficiently hot so it does not freeze when added to the collection solvent but not so hot as to reduce partitioning of the extract and extractant before the extractant leaves the collection solvent. It has a thermal conductivity no greater than 60 BTU's per hour, per square foot, per inch for a one degree Fahrenheit difference.

摘要翻译： 为了避免限流器上的沉积物将通道提取到收集器中，加热的毛细管压力释放限制器在收集阱中具有基本上比毛细管冷的热绝缘出口端。 限流器通过Joulean加热在隔热层和毛细管之间加热。 捕集器中的溶剂的压力高于大气压力5至200 psi。 选择绝缘体的耐热性以将添加到萃取剂中的热量降至最低，并且使提取剂的温度处于足够热的范围内，使其在加入到收集溶剂中时不会冻结，但是 不那么热，以至于在萃取剂离开收集溶剂之前减少提取物和萃取剂的分配。 对于一华氏度的差值，其导热率不大于每小时60BTU，每平方英尺。

公开(公告)号：US5685965A

公开(公告)日：1997-11-11

申请号：US683680

申请日：1996-07-17

申请人： Robert William Allington

发明人： Robert William Allington

IPC分类号： G01N27/447 ,  G01N27/26

CPC分类号： G01N27/44782 ,  G01N27/44721 ,  G01N27/44743

摘要： To detect bands in an electrophoresis capillary tube having a liquid separating medium, a light source and a light detector of a monitor are positioned on opposite sides of the capillary tube with the light source transmitting light through a first slit and light passing to the detector through a second slit after it has passed through the capillary tube. The first and second slits are aligned with the direction of motion of bands, have a maximum length of less than 500 micrometers and a maximum width of less than 200 micrometers. There are no vertical lengths in the capillary tube having a dimension greater than one third of its length between a sample injecting end and a detecting end of the capillary tube. A sample injector includes a vacuum chamber communicating with one end of the capillary tube to pull sample into the other end and a pressure sensor to measure the pressure in said vacuum chamber and generate a signal indicative thereof and integrate it to indicate the amount of sample pulled into the system.

公开(公告)号：US5843294A

公开(公告)日：1998-12-01

申请号：US592833

申请日：1990-10-04

申请人： Robert William Allington

发明人： Robert William Allington

IPC分类号： G01N1/00 ,  G01N27/447 ,  G01N27/26

CPC分类号： G01N27/44721 ,  G01N27/44743 ,  G01N27/44756 ,  G01N27/44782

摘要： To inject sample into a capillary tube of an electrophoresis apparatus, a vacuum tank is connected to one end of the tube while the other end is in sample to impart a pressure difference across the tube. The pressure in the pressure chamber is sensed, integrated and used to determine and control the amount of sample drawn and to correct peak data.

摘要翻译： 为了将样品注射到电泳装置的毛细管中，将真空罐连接到管的一端，而另一端在样品中以在管上施加压力差。 压力室中的压力被感测，积分并用于确定和控制抽取的样品量并纠正峰值数据。