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    Multiple-layer, formed-in-place immunoisolation membrane structures for implantation of cells in host tissue
    1.
    发明授权
    Multiple-layer, formed-in-place immunoisolation membrane structures for implantation of cells in host tissue 失效
    用于在宿主组织中植入细胞的多层形成的免疫隔离膜结构

    公开(公告)号：US6060640A

    公开(公告)日：2000-05-09

    申请号：US446210

    申请日：1995-05-19

    申请人： Robin G. Pauley ,  Donna L. McLarty ,  Atul R. Khare ,  Shmuel Sternberg ,  Daniel R. Boggs ,  Steven Neuenfeldt ,  Mark Jones ,  James H. Brauker ,  Laura A. Martinson

    发明人： Robin G. Pauley ,  Donna L. McLarty ,  Atul R. Khare ,  Shmuel Sternberg ,  Daniel R. Boggs ,  Steven Neuenfeldt ,  Mark Jones ,  James H. Brauker ,  Laura A. Martinson

    IPC分类号： A61F2/02 ,  A61K9/00 ,  A61L27/38 ,  C12N5/08 ,  A61D7/00 ,  A61M31/00

    CPC分类号： A61K9/0024 ,  A61F2/022 ,  A61L27/38

    摘要： A permeable structure forms a chamber to hold living cells. The structure includes a first permeable region surrounding at least a portion of the chamber having a conformation that, when implanted in host tissue, substantially blocks penetration of host cells into the chamber while permitting solute transport. The structure also includes a second permeable region overlying the first permeable region having a conformation that, when implanted in host tissue, forms a permeable interface with host tissue that permits solute transport. A third permeable region is located between the first and second permeable regions. The third region comprises a solution of polymer material formed in place between the first and second permeable regions. The third permeable region bonds the first and second permeable regions together. The third permeable region also has a conformation that, when implanted in host tissue, permits solute transport between the first and second permeable regions. The third, formed-in-place region bonds the first and second permeable regions together, providing a robust, laminated structure that resists delamination during implantation caused by cellular infiltration into discontinuous spaces between the first and second regions. The third, formed-in-place region can also have a conformation providing an immunoisolation effect. Furthermore, the permeability of the third, formed-in-place membrane is sufficient high that it does not adversely effect the permeability value desired for the overall multiple layer membrane structure.

    摘要翻译： 可渗透结构形成容纳活细胞的室。 所述结构包括围绕所述腔室的至少一部分的第一可渗透区域，其具有当植入宿主组织时基本上阻挡宿主细胞渗入所述腔室同时允许溶质运输的构象。 该结构还包括覆盖第一可渗透区域的第二可渗透区域，其具有当植入宿主组织中时形成允许溶质运输的宿主组织的可渗透界面的构象。 第三可渗透区域位于第一和第二可渗透区域之间。 第三区域包括在第一和第二可渗透区域之间形成的聚合物材料溶液。 第三可渗透区域将第一和第二可渗透区域结合在一起。 第三可渗透区域还具有当植入宿主组织时允许溶质在第一和第二可渗透区域之间传输的构象。 第三个就地区域将第一和第二可渗透区域结合在一起，提供坚固的层压结构，其抵抗由于细胞浸润到第一和第二区域之间的不连续空间而在植入过程中的分层。 第三个就地区域也可以具有提供免疫隔离作用的构象。 此外，第三成形膜的渗透性足够高，使得其不会对整个多层膜结构所期望的渗透性值产生不利影响。

    Implantation assembly
    2.
    发明授权
    Implantation assembly 失效
    植入组装

    公开(公告)号：US5964261A

    公开(公告)日：1999-10-12

    申请号：US864209

    申请日：1997-05-28

    申请人： Steven Neuenfeldt ,  Joanne Daugird ,  James Brauker ,  Robin Lee Geller ,  Scott Fredericksen ,  Mark Jones ,  Thomas Loudovaris ,  David Maryanov ,  Stephanie Shors

    发明人： Steven Neuenfeldt ,  Joanne Daugird ,  James Brauker ,  Robin Lee Geller ,  Scott Fredericksen ,  Mark Jones ,  Thomas Loudovaris ,  David Maryanov ,  Stephanie Shors

    IPC分类号： A61L27/00 ,  A61F2/00 ,  A61F2/02 ,  A61K9/00 ,  A61L27/38 ,  A61M31/00

    CPC分类号： A61K9/0024 ,  A61F2/0095 ,  A61L27/36 ,  A61L27/38 ,  A61F2/022

    摘要： An implant assembly and methods for loading implant devices which avoids the accidental deposition of transplanted material or other contaminates on the exterior of the device during transportation, storage, and handling are disclosed. The implant assembly of the invention may be used with a large variety of implant devices for implanting a variety of materials such as cells, tissue or other materials into a host. The implant assembly includes an implant device having an elongated port and a first chamber for holding material for implantation and a container with a second chamber for holding the implant device. The container functions to maintain the sterility and protect the physical integrity of the implant device during loading, storage, cryopreservation and transportation and is removed immediately prior to implantation of the device. The container may optionally include liquid media for cellular growth, maintenance, cryostorage, or transportation purposes.

    摘要翻译： 公开了一种用于装载植入装置的植入物组件和方法，其避免了在运输，储存和处理期间移植材料或其它污染物意外沉积在装置的外部。 本发明的植入物组件可以与各种各样的植入装置一起使用，用于将诸如细胞，组织或其他材料的各种材料植入宿主体内。 植入物组件包括具有细长端口的植入装置和用于保持用于植入的材料的第一腔室和具有用于保持植入装置的第二腔室的容器。 容器用于维持无菌性并且在加载，储存，冷冻保存和运输期间保护植入物装置的物理完整性，并且在植入植入装置之前立即移除。 容器可以任选地包括用于细胞生长，维持，低温保存或运输目的的液体介质。

    Apparatus, system, and method for flash printing
    3.
    发明授权
    Apparatus, system, and method for flash printing 有权
    用于闪光打印的装置，系统和方法

    公开(公告)号：US09573402B2

    公开(公告)日：2017-02-21

    申请号：US14312420

    申请日：2014-06-23

    申请人： Mark Jones

    发明人： Mark Jones

    IPC分类号： B41M5/28 ,  B41M3/00 ,  G03B27/54 ,  B41J2/435

    CPC分类号： B41J2/325 ,  B41J2/435 ,  B41M3/006 ,  B41M5/28 ,  B41M5/287 ,  G03B27/54

    摘要： An apparatus, system, and method to flash print an image. The apparatus includes an energy source that delivers energy. The apparatus includes an energy pulse width modulator coupled to the energy source. The energy pulse width modulator may receive energy from the energy source and modulate the energy received from the energy source. The energy pulse width modulator may be driven by a logic module. The apparatus also includes a plurality of imaging pixels modulated by the energy pulse width modulator and conveying modulated energy to a host material. The host material may be in close proximity to a receiving medium and the modulated energy may release dye from the host material into the receiving medium.

    摘要翻译： 闪光打印图像的装置，系统和方法。 该装置包括能量源，其传送能量。 该装置包括耦合到能量源的能量脉冲宽度调制器。 能量脉冲宽度调制器可以从能量源接收能量并且调制从能量源接收的能量。 能量脉冲宽度调制器可由逻辑模块驱动。 该装置还包括由能量脉冲宽度调制器调制的多个成像像素，并将调制的能量传送到主机材料。 主体材料可以接近接收介质，并且调制的能量可以将染料从主体材料释放到接收介质中。

    Emergency control gas ball valve
    4.
    发明授权
    Emergency control gas ball valve 有权
    紧急控制气球阀

    公开(公告)号：US09103450B2

    公开(公告)日：2015-08-11

    申请号：US13765123

    申请日：2013-02-12

    申请人： Alan Street ,  Mark Jones ,  Mark Wynne ,  Ian Fellows

    发明人： Alan Street ,  Mark Jones ,  Mark Wynne ,  Ian Fellows

    IPC分类号： F16K5/06 ,  F16K27/06

    CPC分类号： F16K5/0657 ,  F16K5/06 ,  F16K27/067 ,  Y10T137/0402

    摘要： An electrically insulating valve includes a body housing a valve mechanism. The body has first and second openings in communication with the valve mechanism. The body is adapted to attach to a first pipe so that the first opening is in communication with the first pipe. An electrically insulating insert having a passage there through is connected to the body so that the passage is in communication with the second opening. The electrically insulating insert is also adapted to be attached to a second pipe.

    摘要翻译： 电绝缘阀包括容纳阀机构的主体。 主体具有与阀机构连通的第一和第二开口。 主体适于附接到第一管，使得第一开口与第一管连通。 具有通过其的通道的电绝缘插入件连接到主体，使得通道与第二开口连通。 电绝缘插入件也适于附接到第二管。

    APPARATUS, SYSTEM, AND METHOD FOR FLASH PRINTING
    5.
    发明申请
    APPARATUS, SYSTEM, AND METHOD FOR FLASH PRINTING 审中-公开
    用于闪存打印的设备，系统和方法

    公开(公告)号：US20140368599A1

    公开(公告)日：2014-12-18

    申请号：US14312420

    申请日：2014-06-23

    申请人： Mark Jones

    发明人： Mark Jones

    IPC分类号： B41J2/435

    CPC分类号： B41J2/325 ,  B41J2/435 ,  B41M3/006 ,  B41M5/28 ,  B41M5/287 ,  G03B27/54

    摘要： An apparatus, system, and method to flash print an image. The apparatus includes an energy source that delivers energy. The apparatus includes an energy pulse width modulator coupled to the energy source. The energy pulse width modulator may receive energy from the energy source and modulate the energy received from the energy source. The energy pulse width modulator may be driven by a logic module. The apparatus also includes a plurality of imaging pixels modulated by the energy pulse width modulator and conveying modulated energy to a host material. The host material may be in close proximity to a receiving medium and the modulated energy may release dye from the host material into the receiving medium.

    摘要翻译： 闪光打印图像的装置，系统和方法。 该装置包括能量源，其传送能量。 该装置包括耦合到能量源的能量脉冲宽度调制器。 能量脉冲宽度调制器可以从能量源接收能量并且调制从能量源接收的能量。 能量脉冲宽度调制器可由逻辑模块驱动。 该装置还包括由能量脉冲宽度调制器调制的多个成像像素，并将调制的能量传送到主机材料。 主体材料可以接近接收介质，并且调制的能量可以将染料从主体材料释放到接收介质中。

    Content capability clearing house systems and methods
    6.
    发明授权
    Content capability clearing house systems and methods 有权
    内容能力清算所系统和方法

    公开(公告)号：US08798083B2

    公开(公告)日：2014-08-05

    申请号：US13551536

    申请日：2012-07-17

    申请人： Parham Momtahan ,  Mark Jones

    发明人： Parham Momtahan ,  Mark Jones

    IPC分类号： H04L12/56

    CPC分类号： H04L67/32 ,  H04L47/15 ,  H04L47/70 ,  H04L47/785 ,  H04L47/805 ,  H04L47/808 ,  H04L67/141 ,  H04L67/16 ,  H04L67/306 ,  H04L67/322 ,  H04L67/327

    摘要： A content capability clearing house that can act as a trusted and neutral mediator among network providers to manage rich content capabilities among multiple networks is provided. Content capabilities that can be brokered include, but are not limited to, quality of service and content screening. In an embodiment, a content capability clearing house includes a receiver that receives content capability request messages and other messages from network providers. A content capability request message includes a quality of service request and/or a subscriber profile request for use with content screening and subscriber specific advertisements. The present invention includes a series of methods for determining content capabilities for data transmission over a transaction between a content provider and a subscriber in which a content capability clearing house is used to efficiently broker and manage the capability among multiple network providers.

    摘要翻译： 提供了一种内容能力清算所，可以在网络提供商之间充当信任和中立的调解员，以管理多个网络之间的丰富的内容功能。 可以经纪的内容功能包括但不限于服务质量和内容筛选。 在一个实施例中，内容能力清算所包括从网络提供商接收内容能力请求消息和其他消息的接收器。 内容能力请求消息包括服务质量请求和/或与内容筛选和用户特定广告一起使用的用户简档请求。 本发明包括一系列用于确定内容提供商和用户之间的事务的数据传输的内容能力的方法，其中使用内容能力清算所来有效地代理和管理多个网络提供商之间的能力。

    Systems and methods for session records correlation
    8.
    发明授权
    Systems and methods for session records correlation 有权
    会话记录相关系统和方法

    公开(公告)号：US08103245B2

    公开(公告)日：2012-01-24

    申请号：US12839103

    申请日：2010-07-19

    申请人： Mark Thistle ,  Mark Jones

    发明人： Mark Thistle ,  Mark Jones

    IPC分类号： H04M11/00

    CPC分类号： H04M15/00 ,  G06Q30/04 ,  H04L12/14 ,  H04L12/1403 ,  H04M15/41 ,  H04M15/43 ,  H04M15/53 ,  H04M15/63 ,  H04M15/8228 ,  H04M15/8292 ,  H04M2215/0164 ,  H04M2215/0172 ,  H04M2215/2026 ,  H04M2215/206 ,  H04M2215/7833 ,  H04W4/24

    摘要： A billing mediation system for use within a communications network that correlates session records pertaining to usage of network resources is disclosed. The billing mediation system includes a record receiver, a record correlator, a look ahead cache, a set of buffers, and a session records database. The set of buffers includes a single segment insert buffer, a multi segment insert buffer, a multi segment update buffer and a billing finalization update buffer. A method for correlating session records is also provided. The method includes receiving a session record, placing the session record into a segment buffer based on the type of record, and updating a look ahead cache including providing a timestamp for the last update for a session. The transfer of correlated session records to a billing system is based on whether records for a session have been received based on session tracking within the look ahead cache.

    摘要翻译： 公开了一种在通信网络内使用的用于关联与网络资源的使用有关的会话记录的计费中介系统。 计费中介系统包括记录接收器，记录相关器，前瞻缓存，一组缓冲器和会话记录数据库。 该缓冲器组包括单段插入缓冲器，多段插入缓冲器，多段更新缓冲器和计费终结更新缓冲器。 还提供了一种用于关联会话记录的方法。 该方法包括接收会话记录，基于记录类型将会话记录放入段缓冲器，以及更新预览高速缓存，包括为会话的最后更新提供时间戳。 将相关会话记录传送到计费系统是基于是否已经基于会话跟踪在前瞻缓存中接收到会话的记录。