利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

111 条记录 (耗时 0.034 秒)

    Respiratory drug condensation aerosols and methods of making and using them
    4.
    发明授权
    Respiratory drug condensation aerosols and methods of making and using them 有权

    公开(公告)号：US08506935B2

    公开(公告)日：2013-08-13

    申请号：US12490102

    申请日：2009-06-23

    申请人： Ron L. Hale ,  Peter M. Lloyd ,  Amy T. Lu ,  Joshua D. Rabinowitz ,  Martin J. Wensley

    发明人： Ron L. Hale ,  Peter M. Lloyd ,  Amy T. Lu ,  Joshua D. Rabinowitz ,  Martin J. Wensley

    IPC分类号： A61K9/12 ,  A61K9/14 ,  A61M15/00 ,  H05B3/00

    CPC分类号： A61K9/0073 ,  A61K9/007 ,  A61K31/522 ,  A61K31/573 ,  Y10S514/958

    摘要： Described herein are respiratory drug condensation aerosols and methods of making and using them. Kits for delivering condensation aerosols are also described. The respiratory drug aerosols typically comprise respiratory drug condensation aerosol particles. In some variations the respiratory drug compound is selected from the group consisting of β-adrenergics, methylxanthines, anticholinergics, corticosteroids, mediator-release inhibitors, anti-leukotriene drugs, asthma inhibitors, asthma antagonists, anti-endothelin drugs, prostacyclin drugs, ion channel or pump inhibitors, enhancers, or modulators and pharmaceutically acceptable analogs, derivatives, and mixtures thereof. Methods of treating a respiratory ailment using the described aerosols are also described. In general, the methods typically comprise the step of administering a therapeutically effective amount of respiratory drug condensation aerosol to a person with a respiratory ailment. Methods of forming a respiratory drug condensation aerosol are also described. The methods comprise the steps of vaporizing and condensing a respiratory drug composition.

    Inhalation device for producing a drug aerosol
    5.
    发明授权
    Inhalation device for producing a drug aerosol 有权
    用于生产药物气溶胶的吸入装置

    公开(公告)号：US07913688B2

    公开(公告)日：2011-03-29

    申请号：US10442385

    申请日：2003-05-20

    申请人： Stephen Cross ,  Craig C. Hodges ,  Ron L. Hale ,  Peter M. Lloyd ,  Daniel J. Myers ,  Reynaldo J. Quintana ,  Joshua D. Rabinowitz ,  Curtis Tom ,  Martin J. Wensley

    发明人： Stephen Cross ,  Craig C. Hodges ,  Ron L. Hale ,  Peter M. Lloyd ,  Daniel J. Myers ,  Reynaldo J. Quintana ,  Joshua D. Rabinowitz ,  Curtis Tom ,  Martin J. Wensley

    IPC分类号： A61M15/08 ,  F23D11/00 ,  F23D14/00

    CPC分类号： A61M15/00 ,  A61M11/002 ,  A61M11/041 ,  A61M11/042 ,  A61M11/047

    摘要： A device for delivering a drug by inhalation is disclosed. The device includes a body defining an interior flow-through chamber having upstream and downstream chamber openings, and a drug supply unit contained within the chamber for producing, upon actuation, a heated drug vapor in a condensation region of the chamber. Gas drawn through the chamber region at a selected gas-flow rate is effective to form drug condensation particles from the drug vapor having a selected MMAD between 0.02 and 0.1 MMAD or between 1 and 3.5 μm. A gas-flow control valve disposed upstream of the unit functions to limit gas-flow rate through the condensation region to the selected gas-flow rate. An actuation switch in the device activates the drug-supply unit, such that the drug-supply unit can be controlled to produce vapor when the gas-flow rate through the chamber is at the selected flow rate.

    摘要翻译： 公开了一种通过吸入传送药物的装置。 该装置包括限定具有上游和下游室开口的内部流通室的主体，以及容纳在该室内的药物供应单元，用于在致动时产生在该室的冷凝区域中的加热的药物蒸气。 以选定的气体流速通过室区域抽吸的气体有效地从具有0.02至0.1MMAD的选定MMAD或1至3.5μm之间的药物蒸气形成药物凝结颗粒。 设置在单元上游的气体流量控制阀用于将通过冷凝区域的气体流量限制到所选择的气体流量。 装置中的致动开关激活药物供应单元，使得当通过腔室的气体流量处于所选择的流速时，可以控制药物供应单元产生蒸汽。

    Respiratory drug condensation aerosols and methods of making and using them
    7.
    发明授权
    Respiratory drug condensation aerosols and methods of making and using them 有权
    呼吸药冷凝气溶胶及其制作和使用方法

    公开(公告)号：US07550133B2

    公开(公告)日：2009-06-23

    申请号：US10719899

    申请日：2003-11-20

    申请人： Ron L. Hale ,  Peter M. Lloyd ,  Amy T. Lu ,  Joshua D. Rabinowitz ,  Martin J. Wensley

    发明人： Ron L. Hale ,  Peter M. Lloyd ,  Amy T. Lu ,  Joshua D. Rabinowitz ,  Martin J. Wensley

    IPC分类号： A61K9/12 ,  A61K9/14 ,  A61M15/00

    CPC分类号： A61K9/0073 ,  A61K9/007 ,  A61K31/522 ,  A61K31/573 ,  Y10S514/958

    摘要： Described herein are respiratory drug condensation aerosols and methods of making and using them. Kits for delivering condensation aerosols are also described. The respiratory drug aerosols typically comprise respiratory drug condensation aerosol particles. In some variations the respiratory drug compound is selected from the group consisting of β-adrenergics, methylxanthines, anticholinergics, corticosteroids, mediator-release inhibitors, anti-leukotriene drugs, asthma inhibitors, asthma antagonists, anti-endothelin drugs, prostacyclin drugs, ion channel or pump inhibitors, enhancers, or modulators and pharmaceutically acceptable analogs, derivatives, and mixtures thereof. Methods of treating a respiratory ailment using the described aerosols are also described. In general, the methods typically comprise the step of administering a therapeutically effective amount of respiratory drug condensation aerosol to a person with a respiratory ailment. Methods of forming a respiratory drug condensation aerosol are also described. The methods comprise the steps of vaporizing and condensing a respiratory drug composition.

    摘要翻译： 本文描述的是呼吸药物冷凝气溶胶及其制备和使用方法。 还描述了用于输送冷凝气溶胶的试剂盒。 呼吸药物气溶胶通常包括呼吸药物凝结气溶胶颗粒。 在一些变化中，呼吸药物化合物选自β-肾上腺素能药，甲基黄嘌呤，抗胆碱能药，皮质类固醇，介质释放抑制剂，抗白三烯药物，哮喘抑制剂，哮喘拮抗剂，抗内皮素药物，前列环素药物，离子通道 或泵抑制剂，增强剂或调节剂及其药学上可接受的类似物，衍生物及其混合物。 还描述了使用所述气溶胶治疗呼吸道疾病的方法。 通常，所述方法通常包括向具有呼吸道疾病的人施用治疗有效量的呼吸药物冷凝气雾剂的步骤。 还描述了形成呼吸药物冷凝气溶胶的方法。 该方法包括蒸发和冷凝呼吸药物组合物的步骤。