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公开(公告)号：US20110172207A1
公开(公告)日：2011-07-14
申请号：US12884113
申请日：2010-09-16
申请人： Rudolf SCHOHE-LOOP , Reinhold Welker , Arnold Paessens , Marcus Bauser , Friederike Stoll , Frank Dittmer , Kerstin Henninger , Daniela Paulsen , Dieter Lang
发明人： Rudolf SCHOHE-LOOP , Reinhold Welker , Arnold Paessens , Marcus Bauser , Friederike Stoll , Frank Dittmer , Kerstin Henninger , Daniela Paulsen , Dieter Lang
IPC分类号： A61K31/4155 , C07D413/06 , C07D403/06 , C07D417/06 , A61K31/5377 , A61K31/553 , A61K31/427 , A61K31/5386 , A61K31/541 , A61K31/496 , A61P31/12 , A61P31/18
CPC分类号： C07D231/14 , A61K31/4155 , C07D401/06 , C07D403/06 , C07D413/06 , C07D417/06 , C07D451/06 , C07D491/08 , C07D498/08
摘要： The present invention relates to novel substituted pyrazolamides, methods for their preparation, their use for the treatment and/or prophylaxis of diseases, as well as their use for the manufacture of medicaments for the treatment and/or prophylaxis of diseases, especially of retroviral diseases, in humans and/or animals.
摘要翻译： 本发明涉及新型取代的吡唑啉酰胺，其制备方法，其用于治疗和/或预防疾病的用途，以及其用于制备用于治疗和/或预防疾病尤其是逆转录病毒疾病的药物的用途 ，在人类和/或动物中。
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公开(公告)号：US08314089B2
公开(公告)日：2012-11-20
申请号：US12884113
申请日：2010-09-16
申请人： Rudolf Schohe-Loop , Reinhold Welker , Arnold Paessens , Marcus Bauser , Friederike Stoll , Frank Dittmer , Kerstin Henninger , Daniela Paulsen , Dieter Lang
发明人： Rudolf Schohe-Loop , Reinhold Welker , Arnold Paessens , Marcus Bauser , Friederike Stoll , Frank Dittmer , Kerstin Henninger , Daniela Paulsen , Dieter Lang
IPC分类号： A61K31/4155 , A61K31/5377 , A61K31/5386 , A61K31/553 , A61K31/496 , C07D413/06 , C07D417/06 , C07D403/06 , A61P31/12
CPC分类号： C07D231/14 , A61K31/4155 , C07D401/06 , C07D403/06 , C07D413/06 , C07D417/06 , C07D451/06 , C07D491/08 , C07D498/08
摘要： The present invention relates to novel substituted pyrazolamides, methods for their preparation, their use for the treatment and/or prophylaxis of diseases, as well as their use for the manufacture of medicaments for the treatment and/or prophylaxis of diseases, especially of retroviral diseases, in humans and/or animals.
摘要翻译： 本发明涉及新型取代的吡唑啉酰胺，其制备方法，其用于治疗和/或预防疾病的用途，以及其用于制备用于治疗和/或预防疾病尤其是逆转录病毒疾病的药物的用途 ，在人类和/或动物中。
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公开(公告)号：US20100105673A1
公开(公告)日：2010-04-29
申请号：US12518717
申请日：2007-12-08
申请人： Adrian Tersteegen , Dirk Heimbach , Kai Thede , Reinhold Welker , Beate Fast , Arnold Paessens , Frank Dittmer , Rudolf Schohe-Loop , Axel Harrenga , Alexander Hillisch , Kerstin Henninger , Walter Hübsch , Marcus Bauser , Susanne Greschat , Dirk Schneider , Tobias Marquardt , Andreas Göller , Andreas Urban , Steffen Wildum , Daniela Paulsen
发明人： Adrian Tersteegen , Dirk Heimbach , Kai Thede , Reinhold Welker , Beate Fast , Arnold Paessens , Frank Dittmer , Rudolf Schohe-Loop , Axel Harrenga , Alexander Hillisch , Kerstin Henninger , Walter Hübsch , Marcus Bauser , Susanne Greschat , Dirk Schneider , Tobias Marquardt , Andreas Göller , Andreas Urban , Steffen Wildum , Daniela Paulsen
IPC分类号： A61K31/365 , A61K31/5377 , A61K31/438 , C07D413/12 , C07D491/107 , C07D307/94 , A61P31/18 , A61P31/12
CPC分类号： C07D307/94 , C07D491/10
摘要： The present invention relates to novel substituted aminofurans, to methods for their preparation, to their use in the treatment and/or prophylaxis of diseases as well as their use in the manufacture of medical products for the treatment and/or prophylaxis of diseases, in particular retroviral disorders, in humans and/or animals.
摘要翻译： 本发明涉及新型取代的氨基呋喃，其制备方法，其用于治疗和/或预防疾病及其在制备用于治疗和/或预防疾病的医药产品中的用途，特别是 逆转录病毒疾病，在人和/或动物中。
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公开(公告)号：US07867992B2
公开(公告)日：2011-01-11
申请号：US11655589
申请日：2007-01-19
申请人： Holger Zimmermann , Rudolf Schohe-Loop , Kerstin Henninger , Dieter Lang , Kai Thede , Chantal Fuerstner , David Brueckner , Daniela Paulsen , Thomas Roelle , Johannes Koebberling , Marcus Bauser
发明人： Holger Zimmermann , Rudolf Schohe-Loop , Kerstin Henninger , Dieter Lang , Kai Thede , Chantal Fuerstner , David Brueckner , Daniela Paulsen , Thomas Roelle , Johannes Koebberling , Marcus Bauser
IPC分类号： A01N43/62 , A61K31/55 , C07D413/00
CPC分类号： C07D215/56 , C07D401/04
摘要： The invention relates to substituted quinolones and to processes for their preparation as well as to their use for the production of medicaments for the treatment and/or prophylaxis of diseases, especially for use as antiviral agents, particularly against cytomegaloviruses.
摘要翻译： 本发明涉及取代的喹诺酮及其制备方法，以及它们用于生产用于治疗和/或预防疾病的药物的用途，特别是用作抗病毒剂，特别是用于巨细胞病毒的药物。
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公开(公告)号：US08318761B2
公开(公告)日：2012-11-27
申请号：US12203793
申请日：2008-09-03
申请人： Niels Svenstrup , Holger Zimmermann , Dagmar Karthaus , Andreas Goeller , Dirk Heimbach , Kerstin Henninger , Dieter Lang , Daniela Paulsen , Bernd Riedl , Rudolf Schohe-Loop , Joachim Schuhmacher , Tobias Wunberg
发明人： Niels Svenstrup , Holger Zimmermann , Dagmar Karthaus , Andreas Goeller , Dirk Heimbach , Kerstin Henninger , Dieter Lang , Daniela Paulsen , Bernd Riedl , Rudolf Schohe-Loop , Joachim Schuhmacher , Tobias Wunberg
IPC分类号： A01N43/40 , A61K31/435 , A61K31/44
CPC分类号： C07D413/04 , C07D213/73
摘要： The invention relates to substituted arylsulfonamides of formula (I) and methods for their preparation as well as their use for the production of medicaments for the treatment and/or prophylaxis of diseases, especially for use as antiviral agents, particularly against cytomegaloviruses.
摘要翻译： 本发明涉及式（I）的取代芳基磺酰胺及其制备方法及其用于生产用于治疗和/或预防疾病的药物的用途，特别是用作抗病毒剂，特别是用于巨细胞病毒的药物。
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公开(公告)号：US20090176842A1
公开(公告)日：2009-07-09
申请号：US12203793
申请日：2008-09-03
申请人： Niels Svenstrup , Holger Zimmermann , Dagmar Karthaus , Andreas Goeller , Dirk Heimbach , Kerstin Henninger , Dieter Lang , Daniela Paulsen , Bernd Riedl , Rudolf Schohe-Loop , Joachim Schuhmacher , Tobias Wunberg
发明人： Niels Svenstrup , Holger Zimmermann , Dagmar Karthaus , Andreas Goeller , Dirk Heimbach , Kerstin Henninger , Dieter Lang , Daniela Paulsen , Bernd Riedl , Rudolf Schohe-Loop , Joachim Schuhmacher , Tobias Wunberg
IPC分类号： A61K31/4439 , C07D413/04 , C07D213/73 , A61P31/12
CPC分类号： C07D413/04 , C07D213/73
摘要： The invention relates to substituted arylsulfonamides of formula (I) and methods for their preparation as well as their use for the production of medicaments for the treatment and/or prophylaxis of diseases, especially for use as antiviral agents, particularly against cytomegaloviruses.
摘要翻译： 本发明涉及式（I）的取代芳基磺酰胺及其制备方法及其用于生产用于治疗和/或预防疾病的药物的用途，特别是用作抗病毒剂，特别是用于巨细胞病毒的药物。
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公开(公告)号：US20070293478A1
公开(公告)日：2007-12-20
申请号：US11655589
申请日：2007-01-19
申请人： Holger Zimmermann , Rudolph Schohe-loop , Kerstin Henninger , Daniela Paulsen , Thomas Roelle , Dieter Lang , Kai Thede , Chantal Fuerstner , David Brueckner , Johannes Koebberling , Marcus Bauser
发明人： Holger Zimmermann , Rudolph Schohe-loop , Kerstin Henninger , Daniela Paulsen , Thomas Roelle , Dieter Lang , Kai Thede , Chantal Fuerstner , David Brueckner , Johannes Koebberling , Marcus Bauser
IPC分类号： A61K31/497 , A61K31/5377 , A61K31/5513 , A61P31/22 , C07D243/08 , C07D401/02 , C07D413/14
CPC分类号： C07D215/56 , C07D401/04
摘要： The invention relates to substituted quinolones and to processes for their preparation as well as to their use for the production of medicaments for the treatment and/or prophylaxis of diseases, especially for use as antiviral agents, particularly against cytomegaloviruses.
摘要翻译： 本发明涉及取代的喹诺酮及其制备方法，以及它们用于生产用于治疗和/或预防疾病的药物的用途，特别是用作抗病毒剂，特别是用于巨细胞病毒的药物。
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公开(公告)号：US07919489B2
公开(公告)日：2011-04-05
申请号：US11894307
申请日：2007-08-20
申请人： Holger Zimmermann , David Brueckner , Kerstin Henninger , Ulrich Rosentreter , Martin Hendrix , Joerg Keldenich , Dieter Lang , Martin Radtke , Daniela Paulsen , Armin Kern
发明人： Holger Zimmermann , David Brueckner , Kerstin Henninger , Ulrich Rosentreter , Martin Hendrix , Joerg Keldenich , Dieter Lang , Martin Radtke , Daniela Paulsen , Armin Kern
IPC分类号： A61P31/12 , A61K31/4178 , A61K31/4164 , C07D401/12 , C07D233/90
CPC分类号： C07D233/90 , C07D401/12
摘要： The invention relates to heterocyclylamide-substituted imidazoles and methods for their preparation, their use for the treatment and/or prophylaxis of diseases as well as their use for the production of medicaments for the treatment and/or prophylaxis of diseases, in particular for the use as antiviral agents, especially against cytomegaloviruses.
摘要翻译： 本发明涉及杂环基酰胺取代的咪唑及其制备方法，它们用于治疗和/或预防疾病及其用于生产用于治疗和/或预防疾病的药物的用途，特别是用于 作为抗病毒剂，特别是针对巨细胞病毒。
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公开(公告)号：US08399682B2
公开(公告)日：2013-03-19
申请号：US12885340
申请日：2010-09-17
申请人： Kai Thede , Susanne Greschat , Steffen Wildum , Daniela Paulsen
发明人： Kai Thede , Susanne Greschat , Steffen Wildum , Daniela Paulsen
IPC分类号： C07D233/32 , A61K31/4166
CPC分类号： C07D403/06 , C07D403/14
摘要： The present invention relates to novel substituted (pyrazolylcarbonyl)imidazolidinones, methods for their preparation, their use for the treatment and/or prophylaxis of diseases, as well as their use for the manufacture of medicaments for the treatment and/or prophylaxis of diseases, especially of retroviral diseases, in humans and/or animals.
摘要翻译： 本发明涉及新的取代的（吡唑基羰基）咪唑啉酮，其制备方法，它们用于治疗和/或预防疾病的用途，以及它们用于制备用于治疗和/或预防疾病的药物的用途，特别是 的逆转录病毒疾病，在人类和/或动物中。
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10.发明授权公开(公告)号：US08546438B2
公开(公告)日：2013-10-01
申请号：US13162522
申请日：2011-06-16
申请人： Kai Thede , Susanne Greschat , Steffen Wildum , Daniela Paulsen
发明人： Kai Thede , Susanne Greschat , Steffen Wildum , Daniela Paulsen
IPC分类号： A61K31/4166 , C07D233/32
CPC分类号： C07D409/06
摘要： The present invention relates to novel substituted (thiophenyl-carbonyl)imidazolidinones, methods for their production, their use for the treatment and/or prevention of diseases, as well as their use for the production of medicaments for the treatment and/or prophylaxis of diseases, especially retroviral diseases, in humans and/or animals.
摘要翻译： 本发明涉及新的取代的（硫代苯基 - 羰基）咪唑啉酮，其制备方法，它们用于治疗和/或预防疾病的用途，以及它们用于生产用于治疗和/或预防疾病的药物 ，特别是逆转录病毒疾病，在人类和/或动物中。
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