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公开(公告)号:US12005443B2
公开(公告)日:2024-06-11
申请号:US17064193
申请日:2020-10-06
Applicant: S.D. Sight Diagnostics Ltd.
Inventor: Ido Bachelet , Joseph Joel Pollak , Daniel Levner , Yonatan Bilu , Noam Yorav-Raphael
CPC classification number: B01L3/502715 , G01N15/1433 , G01N21/23 , G01N21/5907 , G01N21/6458 , B01L2300/0816 , B01L2300/0864 , G01N2015/016 , G01N2015/1006 , G01N2021/5957 , G01N2021/6419 , G01N2021/6421 , G06V2201/03 , G06V2201/04
Abstract: Apparatus and methods are described including successively acquiring a plurality of microscopic images of a portion of a blood sample, and tracking motion of pixels within the successively acquired microscopic images. Trypomastigote parasite candidates within the blood sample are identified, by identifying pixel motion that is typical of trypomastigote parasites. It is determined that the blood sample is infected with trypomastigote parasites, at least partially in response thereto. An output is generated indicating that that the blood sample is infected with trypomastigote parasites. Other applications are also described.
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公开(公告)号:US20240293812A1
公开(公告)日:2024-09-05
申请号:US18654698
申请日:2024-05-03
Applicant: S.D. Sight Diagnostics Ltd.
Inventor: Ido BACHELET , Joseph Joel Pollak , Daniel Levner , Yanatan Bilu , Noam Yorav-Raphael
CPC classification number: B01L3/502715 , G01N15/1433 , G01N21/23 , G01N21/5907 , G01N21/6458 , B01L2300/0816 , B01L2300/0864 , G01N2015/016 , G01N2015/1006 , G01N2021/5957 , G01N2021/6419 , G01N2021/6421 , G06V2201/03 , G06V2201/04
Abstract: Apparatus and methods are described including a digital camera, and a computer processor configured to drive the digital camera to acquire, for each of a plurality of imaging fields of a stained bodily sample, three or more digital images. At least one of the images is a brightfield image and at least two of the images are fluorescent images, each of the fluorescent images being acquired using respective first and second filters, which are different from each other. The computer processor performs image processing on the digital images, by extracting visual classification features from each of the three or more digital images, and identifies one or more entities that are contained within the bodily sample, based upon the image processing. Other applications are also described.
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公开(公告)号:US20200181680A1
公开(公告)日:2020-06-11
申请号:US16705941
申请日:2019-12-06
Applicant: S.D. Sight Diagnostics Ltd.
Inventor: Joseph Joel Pollak , Daniel Levner , Yonatan Bilu , Arnon Houri Yafin , Noam Yorav-Raphael , Yuval Greenfield
Abstract: Apparatus and methods for use with a blood sample are described. The blood sample is stained with Hoechst stain and Acridine Orange stain. A plurality of images of the blood sample are acquired. An object is identified as being a white blood cell candidate. A first stained area, which is stained by the Hoechst stain and which is disposed within the white blood cell candidate, is identified. A second stained area, which is stained by the Acridine Orange stain and which is disposed within the white blood cell candidate, is identified. A white blood cell is detected by determining that structural features of the stained areas satisfy predetermined criteria associated with a white blood cell. Other applications are also described.
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公开(公告)号:US11584950B2
公开(公告)日:2023-02-21
申请号:US16705941
申请日:2019-12-06
Applicant: S.D. Sight Diagnostics Ltd.
Inventor: Joseph Joel Pollak , Daniel Levner , Yonatan Bilu , Arnon Houri Yafin , Noam Yorav-Raphael , Yuval Greenfield
Abstract: Apparatus and methods for use with a blood sample are described. The blood sample is stained with Hoechst stain and Acridine Orange stain. A plurality of images of the blood sample are acquired. An object is identified as being a white blood cell candidate. A first stained area, which is stained by the Hoechst stain and which is disposed within the white blood cell candidate, is identified. A second stained area, which is stained by the Acridine Orange stain and which is disposed within the white blood cell candidate, is identified. A white blood cell is detected by determining that structural features of the stained areas satisfy predetermined criteria associated with a white blood cell. Other applications are also described.
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公开(公告)号:US20160279633A1
公开(公告)日:2016-09-29
申请号:US15174490
申请日:2016-06-06
Applicant: S.D. Sight Diagnostics Ltd
Inventor: Ido Bachelet , Joseph Joel Pollak , Daniel Levner , Yonatan Bilu , Noam Yorav-Raphael
Abstract: Apparatus and methods are described for use with a digital camera that is configured to acquire images of a bodily sample. Two or more stains are configured to stain the bodily sample. A computer processor drives the digital camera to acquire, for each of a plurality of imaging fields of the bodily sample, two or more digital images, at least one of the images being acquired under brightfield lighting conditions, and at least one of the images being acquired under fluorescent lighting conditions. The computer processor performs image processing on the digital images, by extracting visual classification features from the digital images and analyzing the extracted visual classification features. The computer processor outputs a result of the image processing that includes an indication of one or more entities that are contained within the sample. Other applications are also described.
Abstract translation: 描述了与被配置为获取身体样本的图像的数字照相机一起使用的装置和方法。 两个或多个污渍被配置为染色身体样品。 计算机处理器驱动数字照相机以对于身体样本的多个成像场域中的每一个采集两个或更多个数字图像,在明场照明条件下获取至少一个图像,并且至少一个图像是 在荧光照明条件下获得。 计算机处理器通过从数字图像提取视觉分类特征并分析提取的视觉分类特征,对数字图像执行图像处理。 计算机处理器输出包括样本中包含的一个或多个实体的指示的图像处理的结果。 还描述了其它应用。
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