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    Active loss monitor for a harvester
    1.
    发明授权
    Active loss monitor for a harvester 有权

    公开(公告)号：US12225849B2

    公开(公告)日：2025-02-18

    申请号：US17466222

    申请日：2021-09-03

    Applicant: CNH Industrial America LLC

    Inventor： Eric L. Walker ,  Matthew D'Amicantonio ,  Ericson Santos

    IPC: A01D41/127 ,  A01D41/12 ,  A01F7/06 ,  A01F12/18 ,  G01N15/14 ,  G01N33/02 ,  G01N15/1031 ,  G01N15/1433 ,  G01N22/00

    Abstract: A combine has a grain sample sensor for detecting frequencies of impacts of separated grain on the grain sample sensor, a grain loss sensor for detecting frequencies of impacts of residue and lost grain on the grain loss sensor, and a controller. The controller is configured to receive, from the grain sample sensor, the frequencies of the impacts of the separated grain, receive, from the grain loss sensor, the frequencies of the impacts of the residue and the lost grain, set a detection frequency band based on the frequencies of the impacts of the separated grain, filter the frequencies of the impacts of the residue and the lost grain based on the detection frequency band, determine, from the filtered frequencies, grain loss information, and indicate the grain loss information to an operator of the combine, or control the combine based on the grain loss information.

    Method for analysing a biological sample with artefact masking
    2.
    发明授权
    Method for analysing a biological sample with artefact masking 有权

    公开(公告)号：US12209959B2

    公开(公告)日：2025-01-28

    申请号：US18025824

    申请日：2021-09-23

    Applicant: BIOMERIEUX

    Inventor： Dominique Decaux ,  Emilie Bisceglia ,  Guillaume Perrin ,  Philippine Barlas ,  Emilie Collignon

    IPC: G01N21/45 ,  G01N15/1429 ,  G01N15/1433 ,  G01N15/1434

    Abstract: A method for analysing a biological sample by means of an analysis instrument, the sample including biological agents and being arranged in an analysis receptacle in view of a holographic imaging system, the method including: acquiring a holographic image of the sample, the holographic image associating an intensity value with each pixel, determining, from the image acquired, an image mask which associates an active or inactive state with each pixel in accordance with the intensity values so that an inactive state is associated with pixels which correspond to artefacts caused by elements present in the field of view other than biological agents, determining a value of at least one biomass parameter which represents the quantitative spatial distribution of biological agents in the field of view, using only the pixels of the holographic image having an active state, and supplying the value of the biomass parameter from the analysis results.

    SYSTEMS, DEVICES AND METHODS FOR IDENTIFYING, COLLECTING, RELOCATING, AND ANALYZING MICROMETER- AND NANOMETER-SCALE PARTICLES
    3.
    发明申请
    SYSTEMS, DEVICES AND METHODS FOR IDENTIFYING, COLLECTING, RELOCATING, AND ANALYZING MICROMETER- AND NANOMETER-SCALE PARTICLES 有权

    公开(公告)号：US20250022294A1

    公开(公告)日：2025-01-16

    申请号：US18901990

    申请日：2024-09-30

    Applicant: WYONICS LLC

    Inventor： Kristin R. Di Bona ,  Caleb M. Hill

    IPC: G06V20/69 ,  G01N15/1433 ,  G06T7/70

    Abstract: Systems and methods of manipulating nano- and micrometer scale particles are described. The system generally includes an optical imaging system for acquiring an image of a sample of particles, a processor for analyzing the image, identifying a target particle in the image, and determining the lateral position of the target particle in the sample of particles; and a vacuum-based probe system including a moveable probe and a vacuum pump configured to apply a vacuum up through the probe. The processor provides instructions for moving the probe to the lateral position of the target particle, and instructions to apply a vacuum up through the probe such that the target particle is pulled away from the sample of particles and held against the tip of the moveable probe. Once the probe collects and holds a target particle against the tip thereof, the probe can be moved to relocated the target particle to a precise new location, such as on to a particle retrieval tray.

    METHOD AND APPARATUS FOR SORTING AND IDENTIFYING SINGLE CELLS
    5.
    发明申请
    METHOD AND APPARATUS FOR SORTING AND IDENTIFYING SINGLE CELLS 有权

    公开(公告)号：US20240402066A1

    公开(公告)日：2024-12-05

    申请号：US18688364

    申请日：2022-07-04

    Applicant: Shanghai Aurefluidics Technology Co., Ltd

    Inventor： Mengqi WANG ,  Miaomiao YANG ,  Wei JIANG

    IPC: G01N15/1433 ,  G01N15/10 ,  G01N15/1409

    Abstract: A method and an apparatus for sorting and identifying single cells. The method includes a liquid supplying step, first nozzle imaging and recognizing step, single cell printing and imaging step, and second nozzle imaging step. The present disclosure adopts a high-throughput microfluidic design of thermal bubble printing chip and image recognition, which can expel the single cells gently and efficiently, thereby obtaining a high volume of single cells with high single cell yield and high single cell activity quickly. The method recognizes single cells based on cellular morphological features, facilitating obtaining single cells with high activity. Furthermore, the method provides the appearance of single cells on day zero, an important criterion for single cell analysis. The apparatus of the present disclosure provides a comprehensive solution for cellular experiments by monitoring the cell growth and locating the target cells based on fluorescent markers after single cell sorting.

    FLUIDIC DEVICE AND METHOD FOR PREPARING A SAMPLE SUBSTRATE
    6.
    发明申请
    FLUIDIC DEVICE AND METHOD FOR PREPARING A SAMPLE SUBSTRATE 有权

    公开(公告)号：US20240399380A1

    公开(公告)日：2024-12-05

    申请号：US18799539

    申请日：2024-08-09

    Applicant: ILLUMINA, INC.

    Inventor： Darryl Donovan

    IPC: B01L9/00 ,  B01L3/00 ,  B01L7/00 ,  G01N15/10 ,  G01N15/14 ,  G01N15/1433 ,  G01N21/03 ,  G01N21/64

    Abstract: Fluidic device includes a manifold body having first and second body sides. The first body side has receiving ports forming a port array that defines a reaction region. The second body side has open-sided recesses forming reaction chambers when the fluidic device is mounted onto a sample substrate. The reaction chambers form a chamber array that defines a fluid-delivery region. The reaction region is greater than the fluid-delivery region. The manifold body also includes vent openings that open to an exterior. The fluidic device also includes upstream channels extending through the manifold body. Each of the upstream channels fluidly couples a corresponding receiving port of the port array to a corresponding reaction chamber of the chamber array. The fluidic device also includes venting channels extending through the manifold body. Each of the venting channels fluidly couples a corresponding reaction chamber of the chamber array to a corresponding vent opening.

    Systems, devices and methods for identifying, collecting, relocating, and analyzing micrometer- and nanometer-scale particles
    7.
    发明授权
    Systems, devices and methods for identifying, collecting, relocating, and analyzing micrometer- and nanometer-scale particles 有权

    公开(公告)号：US12136283B2

    公开(公告)日：2024-11-05

    申请号：US18559769

    申请日：2023-04-11

    Applicant: WYONICS LLC

    Inventor： Kristin R. Di Bona ,  Caleb M. Hill

    IPC: G06V20/69 ,  G01N15/1433 ,  G06T7/70

    Abstract: Systems and methods of manipulating nano- and micrometer scale particles are described. The system generally includes an optical imaging system for acquiring an image of a sample of particles, a processor for analyzing the image, identifying a target particle in the image, and determining the lateral position of the target particle in the sample of particles; and a vacuum-based probe system including a moveable probe and a vacuum pump configured to apply a vacuum up through the probe. The processor provides instructions for moving the probe to the lateral position of the target particle, and instructions to apply a vacuum up through the probe such that the target particle is pulled away from the sample of particles and held against the tip of the moveable probe. Once the probe collects and holds a target particle against the tip thereof, the probe can be moved to relocated the target particle to a precise new location, such as on to a particle retrieval tray.

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