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公开(公告)号：US11192120B2
公开(公告)日：2021-12-07
申请号：US16472374
申请日：2017-12-18
Applicant: SHIMADZU CORPORATION
Inventor： Kengo Aoki , Hiroki Honda
Abstract: Provided is a centrifugal field-flow fractionation device that can stably press a fixing member toward an inner peripheral surface of a rotor by a wedge-shaped member, even when a relatively large centrifugal force acts on the wedge-shaped member. An arc-shaped (C-shaped) fixing member 17 is provided along an inner peripheral surface of a channel member 16 on a side of a rotation axis of the channel member 16. A wedge-shaped member 18 is attached between opposite ends of the fixing member 17 and applies a force in a direction of spreading the opposite ends apart, to thereby press the fixing member 17 toward the inner peripheral surface of the rotor 14. The wedge-shaped member 18 has a pair of contact surfaces 184 that respectively come into contact with the opposite ends of the fixing member 17. The pair of contact surfaces 184 include tapered surfaces that gradually taper down toward the rotor 14, so that the distance between the contact surfaces 184 gradually shortens as the contact surfaces 184 come close to the rotor 14.
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公开(公告)号：US11105423B2
公开(公告)日：2021-08-31
申请号：US16470305
申请日：2017-12-11
Applicant: SHIMADZU CORPORATION , EAGLE INDUSTRY CO., LTD.
Inventor： Kengo Aoki , Hiroki Honda , Hidekazu Takahashi
IPC: F16J15/36
Abstract: A mechanical sealing device according to an embodiment of the present invention includes: a sealing ring (13) attached to a protrusion (11a) protruding from a housing (11); a mating ring (23) attached to an end portion of a rotary shaft (21); a welded bellows provided around the protrusion (11a) and located between the housing (11) and the sealing ring (13). The welded bellows (15) presses the sealing ring (13) in an axial direction to cause the sealing ring (13) to be in contact with the mating ring (23), thereby ensuring high pressure force, and in particular, uniform pressure force along its entire circumference, so as to achieve high liquid tightness, while maintaining the sizes in axial and radial directions small. Furthermore, the welded bellows (15) works as a sealing member of blocking a liquid leaked out through the O-ring (14), thereby achieving assured liquid tightness. Accordingly, an outside-type mechanical sealing device can be provided which has a compact size, and is capable of ensuring high liquid tightness in response to a high rotation speed and a high liquid pressure.
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公开(公告)号：US11774412B2
公开(公告)日：2023-10-03
申请号：US16471637
申请日：2016-12-22
Applicant: SHIMADZU CORPORATION
Inventor： Hiroki Honda , Kengo Aoki , Haruhisa Kato
CPC classification number: G01N30/0005 , B03B5/28 , B04B5/0442 , B04B9/14 , B04B2005/045 , G01N2030/002
Abstract: A centrifugal separation type FFF device where a rotor can be rotated at a high speed safely so that particles of a smaller size in a sample liquid can be classified. A field flow fractionation device is provided with: a channel that is attached to the inner circumferential surface of the peripheral portion of a rotor and where a classification flow path is created; flow paths for feeding a sample liquid into and out from the classification flow path; and a rotational drive mechanism for rotating the rotational axis, wherein a channel installation portion is formed on one side of the peripheral portion, and a mass balancer portion for adjusting the mass distribution of the rotor is formed on the other side with the rotor base in between.
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公开(公告)号：US11506640B2
公开(公告)日：2022-11-22
申请号：US16485195
申请日：2018-01-26
Applicant: SHIMADZU CORPORATION
Inventor： Kengo Aoki , Masahide Gunji
IPC: G01N30/16
Abstract: Obtaining sufficient suppression effect of channel diffusion and stably transferring solution are made possible even in a piping having an extremely small inner diameter used for an analysis apparatus such as an HPLC. A piping device for an analysis apparatus includes a piping equipped with a folded shape that suppresses inner channel diffusion, and a member directly or indirectly in contact with the piping from at least one side to support the piping to suppress deformation of the folded shape.
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公开(公告)号：US20150276688A1
公开(公告)日：2015-10-01
申请号：US14668000
申请日：2015-03-25
Applicant: SHIMADZU CORPORATION
Inventor： Kengo Aoki , Keisuke Ogawa
CPC classification number: G01N30/34 , B01D15/08 , B01D15/16 , B01D15/166 , B01D15/18 , G01N30/20 , G01N30/8658 , G01N30/8665 , G01N30/8675 , G01N2030/347 , G01N2030/383 , G01N2030/385
Abstract: A liquid chromatograph has a mobile phase delivery section including, between mobile phase channels connected respectively to a plurality of mobile phase containers and a delivery pump, channel switching valves for selecting one of the mobile phase channels. This liquid chromatograph whose channel switching valves have a hierarchical structure including at least two stages includes a valve connection state setting section that is configured to set the connection state between the channel switching valves and the connection state between the channel switching valves and the mobile phase channels, and further includes a per channel total delivery amount calculation section that is configured to calculate the total delivery amount of mobile phase per mobile phase channel based on a connection state according to the valve connection state setting section, the delivery amount per unit time by the delivery pump, and the operation time of the delivery pump.
Abstract translation: 液相色谱仪具有流动相递送部分，其包括分别连接到多个流动相容器的流动相通道和输送泵之间，用于选择流动相通道之一的通道切换阀。 这种液相色谱仪的通道切换阀具有包括至少两级的分层结构，包括阀连接状态设定部，其被配置为设置通道切换阀之间的连接状态和通道切换阀与流动相通道之间的连接状态 并且还包括每通道总量递送量计算部分，其被配置为基于根据阀连接状态设置部分的连接状态来计算每个移动通道的流动相的总输送量，每单位时间的输送量由 输送泵，以及输送泵的运行时间。
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Patent Agency Ranking
公开(公告)号：USD969339S1
公开(公告)日：2022-11-08
申请号：US29766964
申请日：2021-01-20
Applicant: SHIMADZU CORPORATION
Designer： Tomoya Sugie , Kengo Aoki
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公开(公告)号：US11253873B2
公开(公告)日：2022-02-22
申请号：US16471668
申请日：2017-12-18
Applicant: SHIMADZU CORPORATION
Inventor： Kengo Aoki , Hiroki Honda , Haruhisa Kato
Abstract: A centrifugal field-flow fractionation device capable of improving analysis performance and shortening analysis time is provided. A first channel 111 communicating with a channel member is formed on a rotational shaft 11 that rotates together with a rotor. A second channel 644 communicating with the first channel 111 is formed on a fixing portion 60 fixed in a state of facing the rotational shaft 11 along a rotational axis L. A mechanical seal 66 having a pair of seal rings 661 and 662 that come into contact with each other and a biasing member 663 is provided to attach one seal ring 661 to the rotational shaft 11 and the other seal ring 662 to the fixing portion 60. The biasing member 663 biases the pair of seal rings 661 and 662 in a direction in which the pair of seal rings come in contact with each other. Since the rotational shaft 11 can be rotated at a high speed and the liquid sample can be fed at a high pressure, the analysis performance can be improved and the analysis time can be shortened.
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公开(公告)号：US11433404B2
公开(公告)日：2022-09-06
申请号：US16471664
申请日：2016-12-22
Applicant: SHIMADZU CORPORATION
Inventor： Kengo Aoki , Ryutaro Oda
Abstract: A centrifugal field-flow fractionation device includes an annular rotor, an arc-shaped channel member, a rotation drive unit, and a restriction unit. A channel member 16 is provided along an inner peripheral surface of the rotor, has therein a channel 161 for a liquid sample by laminating a plurality of layers, and has an inlet for the liquid sample to the channel 161 and an outlet for the liquid sample from the channel 161. By rotating the rotor, particles in the liquid sample in the channel 161 are classified by centrifugal force. A restriction spacer 64 restricts the channel 161 from being compressed to a height less than a certain height when the channel member 16 is compressed and deformed in a laminating direction.
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公开(公告)号：US11407146B2
公开(公告)日：2022-08-09
申请号：US16471938
申请日：2016-12-22
Applicant: SHIMADZU CORPORATION
Inventor： Kengo Aoki
Abstract: A centrifugal field-flow fractionation device 1 includes a rotation unit 10, a rotation sensor 41, a first vibration sensor 51, a second vibration sensor 52, and an imbalance amount calculation unit 312. When an imbalance occurs in the rotation unit 10, the imbalance amount calculation unit 312 calculates the imbalance amount, based on a detection signal from the rotation sensor 41, a detection signal from the first vibration sensor 51, and a detection signal from the second vibration sensor 52. That is, when an imbalance occurs in the rotation unit 10, the imbalance is calculated by the configuration in the centrifugal field-flow fractionation device 1.
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公开(公告)号：US09863968B2
公开(公告)日：2018-01-09
申请号：US14669094
申请日：2015-03-26
Applicant: SHIMADZU CORPORATION
Inventor： Kengo Aoki
CPC classification number: G01N35/0092 , G01N35/00732 , G01N2035/00831 , G01N2035/00851 , G01N2035/00891 , G01N2035/0094 , G01N2035/0493 , G05B15/02
Abstract: Vials (samples) as analysis targets to be set in a batch table for serial analyses are allowed to be designated simply and highly flexibly. On a batch table setting screen 100, a sample region designation method selecting button 120, an analysis direction selecting button 121, a plate image display area 125 and other components are arranged. A sample region designation method and an analysis direction are selected simply by clicking the buttons. The start position and the end position of analyses are designated by a drag-and-drop operation using a mouse on a plate image displayed in the plate image display area 125. The vials selected during a process of the drag-and-drop operation are displayed in a color discriminable from other vials. Accordingly, a simple, graphical operation can create a batch table in which the multiple vials mounted on the sample plate are set as analysis targets in a desired order.
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