公开(公告)号：US10302604B2

公开(公告)日：2019-05-28

申请号：US13783922

申请日：2013-03-04

申请人： SHIMADZU CORPORATION

发明人： Keisuke Ogawa ,  Yoshiaki Maeda

IPC分类号： G01N30/34 ,  G01N30/50 ,  G01N30/24

摘要： A solvent delivery device includes a solvent delivery pump and a flow path switching valve. The flow path switching valve is connected to downstream ends of mobile phase sending flow paths and the solvent delivery pump is to be connected to one of the mobile phase sending flow paths by switching the flow path switching valve. At least one of the mobile phase sending flow paths includes a buffer solution sending flow path. The buffer solution sending flow path includes a butler solution storage section, a cleaning solution storage section, and a mobile phase switching valve for switching connection of the flow path switching valve to one of the storage sections.

公开(公告)号：US09651526B2

公开(公告)日：2017-05-16

申请号：US14668000

申请日：2015-03-25

申请人： SHIMADZU CORPORATION

发明人： Kengo Aoki ,  Keisuke Ogawa

IPC分类号： G01N30/34 ,  B01D15/16 ,  B01D15/18 ,  B01D15/08 ,  G01N30/20 ,  G01N30/38 ,  G01N30/86

CPC分类号： G01N30/34 ,  B01D15/08 ,  B01D15/16 ,  B01D15/166 ,  B01D15/18 ,  G01N30/20 ,  G01N30/8658 ,  G01N30/8665 ,  G01N30/8675 ,  G01N2030/347 ,  G01N2030/383 ,  G01N2030/385

摘要： A liquid chromatograph has a mobile phase delivery section including, between mobile phase channels connected respectively to a plurality of mobile phase containers and a delivery pump, channel switching valves for selecting one of the mobile phase channels. This liquid chromatograph whose channel switching valves have a hierarchical structure including at least two stages includes a valve connection state setting section that is configured to set the connection state between the channel switching valves and the connection state between the channel switching valves and the mobile phase channels, and further includes a per channel total delivery amount calculation section that is configured to calculate the total delivery amount of mobile phase per mobile phase channel based on a connection state according to the valve connection state setting section, the delivery amount per unit time by the delivery pump, and the operation time of the delivery pump.

公开(公告)号：US12092099B2

公开(公告)日：2024-09-17

申请号：US16612380

申请日：2017-07-03

申请人： SHIMADZU CORPORATION

发明人： Keisuke Ogawa ,  Shinya Imamura

IPC分类号： F04B51/00 ,  F04B1/16 ,  F04B13/00 ,  F04B49/24 ,  F04B53/10

CPC分类号： F04B51/00 ,  F04B1/16 ,  F04B13/00 ,  F04B49/24 ,  F04B53/10 ,  F04B2201/0605

摘要： A liquid feeding device includes a primary plunger pump; a secondary plunger pump connected downstream; a check valve provided between the primary plunger pump and the secondary plunger pump; a primary pressure sensor that detects a pressure in the pump chamber of the primary plunger pump; a liquid feeding control part configured to control operations of the primary plunger pump and the secondary plunger pump; and a liquid leakage detector configured to detect liquid leakage in the check valve based on a change in an output value of the primary pressure sensor during the waiting time. The liquid feeding control part is configured to control the operation of the primary plunger pump so that a waiting time, where the primary plunger pump stops without operating, is present while a discharge operation by the secondary plunger pump is performed after a suction by the primary plunger pump is completed.

公开(公告)号：US11746777B2

公开(公告)日：2023-09-05

申请号：US16768660

申请日：2018-06-20

申请人： SHIMADZU CORPORATION

发明人： Shinya Imamura ,  Keisuke Ogawa

IPC分类号： F04B53/10 ,  F16K31/06 ,  F04B7/00 ,  F04B49/22 ,  F16K31/08 ,  G01N30/32

CPC分类号： F04B53/1087 ,  F04B7/0076 ,  F04B53/1002 ,  F16K31/0655 ,  F04B49/22 ,  F16K31/08 ,  G01N30/32 ,  G01N2030/326

摘要： A liquid sending device includes a plunger pump, which performs an intake operation of liquid to and a discharge operation of liquid from a pump chamber and in which pressure in the pump chamber in a case where the intake operation is performed is lower compared to a case where the discharge operation is performed, a check valve that is provided at an inlet port, has a spherical valve element and a valve seat, and passively operates according to the pressure in the pump chamber in such a direction that the valve element is seated on or detached, a pressure sensor that detects the pressure, and an attachment detector that compares the pressure with a preset threshold value and detect attachment of the valve element to the valve seat in a case where the pressure in the pump chamber is equal to or lower than the threshold value.

公开(公告)号：US09877368B2

公开(公告)日：2018-01-23

申请号：US15015810

申请日：2016-02-04

申请人： SHIMADZU CORPORATION

发明人： Yusuke Nagai ,  Keisuke Ogawa ,  Masato Watanabe ,  Kumiko Jingu ,  Masanori Fujiwara ,  Tomoyuki Yamazaki

IPC分类号： H05B33/08 ,  G01N21/33

CPC分类号： H05B33/0851 ,  G01N21/33 ,  G01N2201/0621 ,  G01N2201/0638 ,  G01N2201/0692 ,  G01N2201/0695

摘要： Provided is an optical analyzer for performing a feedback control on the amount of light emitted from an LED as a light source, in which the configuration of an optical system is made simple and the degree of freedom in optical system arrangement is secured. An optical member 2 for focusing most of light while discharging part of the light as unfocused light is provided on an optical path from a light casting unit 1 to a sample cell 3. The optical member 2 can be achieved with a simple configuration, for example, two ball lenses spaced apart by a predetermined distance from each other. The light focused by the optical member 2 is cast as measurement light into the sample cell 3. Meanwhile, a second photodetector 5 is arranged at a position where the unfocused light reaches. The second photodetector 5 generates a detection signal in accordance with the amount of light that has entered the second photodetector 5 as monitored light, and a drive current to be supplied to an LED is controlled through a drive current controlling unit 6 and a current source 7 such that the amount of light is maintained at a fixed level.

公开(公告)号：US12105069B2

公开(公告)日：2024-10-01

申请号：US17438421

申请日：2019-10-16

申请人： SHIMADZU CORPORATION

发明人： Tomohiro Gomi ,  Daisuke Kitabayashi ,  Shinya Imamura ,  Keisuke Ogawa ,  Masataka Nikko ,  Masahide Gunji

IPC分类号： G01N30/86 ,  G01N30/02 ,  G01N30/32

CPC分类号： G01N30/8658 ,  G01N30/32 ,  G01N2030/027

摘要： A liquid sending failure detector acquires periodically a liquid sending pressure of a liquid sending mechanism consecutively sends liquid using at least one plunger pump that sends liquid by reciprocally driving a plunger such that a fluctuation is read in one driving period of the liquid sending mechanism, and detect a liquid sending failure of the liquid sending mechanism using an acquired liquid sending pressure. The liquid sending failure detector executes a pulsation detection step of obtaining a fluctuation range of the liquid sending pressure in a certain driving period of the liquid sending mechanism and detecting pulsation on a condition that a count of consecutive periods in which the fluctuation range exceeds a predetermined reference value exceeds a predetermined reference count, and a liquid sending failure detection step of detecting a liquid sending failure of the liquid sending mechanism when the pulsation is detected in the pulsation detection step.

公开(公告)号：US11921094B2

公开(公告)日：2024-03-05

申请号：US17438418

申请日：2019-03-13

申请人： SHIMADZU CORPORATION

发明人： Tomohiro Gomi ,  Daisuke Kitabayashi ,  Shinya Imamura ,  Keisuke Ogawa

IPC分类号： G01N30/86 ,  G01N30/32 ,  G01N30/02

CPC分类号： G01N30/8675 ,  G01N30/32 ,  G01N2030/027

摘要： Liquid sent by a liquid sending pump flows through an analysis flow path. A sample is injected into the analysis flow path. A separation column is provided in the analysis flow path. A sample injected in the separation column is separated into components, and sample components obtained by separation are detected by a detector. The number of liquid sending pumps and a connection structure of the liquid sending pumps connected to the analysis flow path are specified by a system configuration specifier as a system configuration. A condition for detecting a liquid sending failure in a liquid sending pump that is preset for each type of system configuration is held by a condition holder. A condition corresponding to a system configuration is determined from conditions held by the condition holder. A liquid sending failure in a liquid sending pump is detected with use of the determined condition.

公开(公告)号：US11434897B2

公开(公告)日：2022-09-06

申请号：US16629421

申请日：2017-07-28

申请人： SHIMADZU CORPORATION

发明人： Jun Yanagibayashi ,  Keisuke Ogawa

IPC分类号： F04B49/06 ,  F04B11/00 ,  F04B13/00 ,  F04B23/06 ,  F04B1/02

摘要： A liquid feeding device includes a discharge channel, a pump part, a feeding pressure sensor, a non-discharge pressure sensor, a pre-compression part, and a pre-compression speed determination part. The pump part has plunger pumps connected in series or parallel. At least one of the plunger pumps is a closed pump in which communication with the discharge channel is disconnected during a non-discharge time. The pre-compression part causes the closed pump that is after the suction process for sucking the liquid into a pump chamber is completed and during the non-discharge time to execute a pre-compression process to perform a discharge operation until a non-discharge pressure is substantially the same as a feeding pressure based on output of the feeding pressure sensor and output of the non-discharge pressure sensor. The pre-compression speed determination part determines a pre-compression speed of the closed pump in the pre-compression process.

公开(公告)号：US11307179B2

公开(公告)日：2022-04-19

申请号：US16648077

申请日：2017-10-23

申请人： SHIMADZU CORPORATION

发明人： Jun Yanagibayashi ,  Shinya Imamura ,  Keisuke Ogawa ,  Masataka Nikko ,  Shinichi Fujisaki

IPC分类号： G01N30/32 ,  F04B49/20 ,  G01N30/34 ,  F04B23/06 ,  F04B49/06 ,  B01D15/16 ,  F04B11/00 ,  G01N30/02

摘要： The liquid feeding device includes a discharge speed calculation part configured to calculate a discharge speed v of the plunger pump so that a converted value LATM under an atmospheric pressure of a flow rate LPRE of the mobile phase discharged to the discharge channel from the pump part becomes a set flow rate LSET using a volume V of the mobile phase in the pump chamber of the closing pump immediately before the precompression process is started, a volume ΔV reduced due to the precompression process of the mobile phase in the pump chamber of the closing pump, and a feeding pressure P; and a discharge operation controller configured to control a discharge speed of the plunger pump to a discharge speed v calculated by the discharge speed calculation part.

公开(公告)号：US20130233060A1

公开(公告)日：2013-09-12

申请号：US13783922

申请日：2013-03-04

申请人： SHIMADZU CORPORATION

发明人： Keisuke Ogawa ,  Yoshiaki Maeda

IPC分类号： G01N30/50

CPC分类号： G01N30/50 ,  G01N30/24 ,  G01N30/34

摘要： A solvent delivery device comprises a solvent delivery pump and a flow path switching valve. The flow path switching valve is connected to downstream ends of mobile phase sending flow paths and the solvent delivery pump is to be connected to one of the mobile phase sending flow paths by switching the flow path switching valve. At least one of the mobile phase sending flow paths includes a buffer solution sending flow path, and the buffer solution sending flow path includes a buffer solution storage section, a cleaning solution storage section, and a mobile phase switching valve for switching connection of the flow path switching valve to one of the storage sections.

摘要翻译： 溶剂输送装置包括溶剂输送泵和流路切换阀。 流路切换阀连接到流动相发送流路的下游侧，通过切换流路切换阀，将溶剂输送泵连接到流动相发送流路之一。 移动阶段发送流程路径中的至少一个包括缓冲解决方案发送流程，缓冲器解决方案发送流程路径包括缓冲溶液存储部分，清洗溶液存储部分和用于切换流程连接的流动相切换阀 路径切换阀到其中一个存储部分。