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公开(公告)号：US20240148953A1
公开(公告)日：2024-05-09
申请号：US18544739
申请日：2023-12-19
申请人： DSM IP Assets B.V.
CPC分类号： A61M1/3693 , A61M1/3696 , B01D21/262 , B01D21/34 , B04B1/02 , B04B1/18 , B04B5/0407 , B04B5/0442 , B04B7/08 , B04B11/04 , B04B1/14
摘要： Centrifuges are useful to, among other things, remove red blood cells from whole blood and retain platelets and other factors in a reduced volume of plasma. Platelet rich plasma (PRP) and or platelet poor plasma (PPP) can be obtained rapidly and is ready for immediate injection into the host. Embodiments may include valves, operated manually or automatically, to open ports that discharge the excess red blood cells and the excess plasma into separate receivers while retaining the platelets and other factors in the centrifuge chamber. High speeds used allow simple and small embodiments to be used at the patient's side during surgical procedures. The embodiments can also be used for the separation of liquids or slurries in other fields such as, for example, the separation of pigments or lubricants.
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公开(公告)号：US11964286B2
公开(公告)日：2024-04-23
申请号：US16842205
申请日：2020-04-07
申请人： Terumo BCT, Inc.
CPC分类号： B04B7/08 , A61M1/36224 , A61M1/36225 , A61M1/362265 , B04B1/02 , B04B15/12 , C12M47/02
摘要： A frustro-conical chamber for separating particles in a fluidized bed for blood component or cell separation. The chamber is characterized by an injection-directing surface for directing inflowing fluid along a frustro-conical wall of the chamber. A dam adjacent the cell-injection port may be circumferentially disposed within the chamber and may have its maximum height adjacent an injection port, and the height may diminish away from the injection port. The injection directing surface may comprise a shelf extending into the interior of the chamber from the injection port, thereby impeding fluid flow in the direction of an outlet port.
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公开(公告)号：US20230302465A1
公开(公告)日：2023-09-28
申请号：US18006270
申请日：2021-07-20
发明人： Gerard MELLING
CPC分类号： B04B5/10 , B01D21/262 , B01D21/265 , B03B5/34 , B04B1/02 , B04B11/02
摘要： The invention provides an apparatus for separating components of a fluid stream, the apparatus comprising:
(a) a support structure on which is mounted a rotatable centrifugal separator chamber in which separation of the components of the fluid stream occurs;
(b) a fluid inlet for introducing a pressurised source of the fluid stream to be separated into the centrifugal separator chamber;
(c) a fluid outlet for collecting one or more separated components of the fluid stream;
(d) a vortex-creating device which rotates in order to introduce a vortex to the fluid stream in the centrifugal separation chamber thereby to bring about centrifugal separation of the components of the fluid stream;
and wherein the centrifugal separator chamber and vortex-creating device are configured to rotate independently of each other.
The invention also provides a method for separating components of a suspension, the method comprising passing the suspension through an apparatus as described herein.-
公开(公告)号：US20210387149A1
公开(公告)日：2021-12-16
申请号：US17295175
申请日：2019-11-07
申请人： DIC Corporation
发明人： Kohei Hayakawa , Kenji Sugo , Yoshihiro Sato , Yutaro Ueda , Hiroyuki Oominato , Shinichi Okada
摘要： The problem to be solved by the present invention is to provide a method for producing an aqueous pigment dispersion that has certain dispersion stability with which the formation of coarse particles with time and the settling of a pigment and the like with time can be reduced and that can be used for producing an ink having excellent discharge stability. The present invention relates to a method for producing an aqueous pigment dispersion, the method including kneading a composition including a pigment including one or more materials selected from the group consisting of a violet pigment, a green pigment, and an orange pigment and a resin, the composition having a nonvolatile content of 50% by mass or more, under predetermined conditions and subsequently performing a centrifugation treatment.
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公开(公告)号：US11174458B2
公开(公告)日：2021-11-16
申请号：US16219001
申请日：2018-12-13
发明人： Rolf Wolters , Jules Valenti , Tom Gurski
摘要： Cell separation systems and methods of separating cells are disclosed. In an embodiment, a cell separation system is described that comprises a non-transitory storage device that executes a centrifugation program to separate cell volume from biologic material volume; a heating mechanism; a containment mechanism; and an assembly comprised of a single-walled centrifugation bowl. In an embodiment, methods of separating cells are disclosed whereby cells are separated by agitating a volume of biologic material and a volume digestion media to form a digested volume of biologic material; centrifuging the digested volume of biologic material; removing a portion of a resulting waste via at least one fluid outlet; isolating a different portion of the waste, and removing the concentrated cell volumes from the reservoir.
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公开(公告)号：US20210205824A1
公开(公告)日：2021-07-08
申请号：US17059263
申请日：2019-04-26
发明人： Takato KOMURA
摘要： In a continuous centrifuge, a core end surface component separated from a core body is arranged inside a rotor, an air trap mechanism which automatically captures bubbles inside a sample is formed, and the bubbles are removed by centrifugal separation before the sample is sent to an outer circumferential portion having a high liquid pressure. In addition, when viewed in the axial direction, the core body and an upper rotor cover abut each other, and the core end surface component and a lower rotor cover abut each other, with appropriate pressure by biasing the core end surface component and the core body with a spring. Because a flow path between the rotor core and the rotor covers is maintained in a perfect state and the bubbles in liquid are also removed, the flow path may not be blocked by the bubbles and the centrifugal separation can be stably performed.
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公开(公告)号：US20200001308A1
公开(公告)日：2020-01-02
申请号：US16471664
申请日：2016-12-22
申请人： SHIMADZU CORPORATION
发明人： Kengo AOKI , Ryutaro ODA
摘要： A centrifugal field-flow fractionation device includes an annular rotor, an arc-shaped channel member, a rotation drive unit, and a restriction unit. A channel member 16 is provided along an inner peripheral surface of the rotor, has therein a channel 161 for a liquid sample by laminating a plurality of layers, and has an inlet for the liquid sample to the channel 161 and an outlet for the liquid sample from the channel 161. By rotating the rotor, particles in the liquid sample in the channel 161 are classified by centrifugal force. A restriction spacer 64 restricts the channel 161 from being compressed to a height less than a certain height when the channel member 16 is compressed and deformed in a laminating direction.
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公开(公告)号：US20190240680A1
公开(公告)日：2019-08-08
申请号：US16319922
申请日：2017-12-16
发明人： Kazushige HAYAKAWA
IPC分类号： B04B9/08 , B04B1/02 , B04B9/10 , B04B11/02 , F16J15/447
摘要： A centrifugal separator includes a rotating body driving and sealing structure in which a hermetically sealed space is formed between a rotating body and an outer case by sealing the inside and outside using a noncontact seal during rotation of the rotating body, in an airtight manner. A rotation coupling unit is provided at the upper end of a centrifugal cylinder, and even when the centrifugal cylinder is deformed during use causing an internal fluid to leak through a fitting portion of a bottom member to the centrifugal cylinder, the fluid leaks in the hermetically sealed space so that the driving system or the like is not contaminated.
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公开(公告)号：US20190111443A1
公开(公告)日：2019-04-18
申请号：US16097240
申请日：2017-03-23
发明人： Tetsu NAGABAYASHI
摘要： Provided is a lid stand that can accommodate a lid of a sealed rotating container of a centrifugal smearing device in a leaned state and so that liquid dripping can be prevented, without securing a wide space on a desk, and that can similarly lower a risk of touching a liquid specimen also for both right-handed and left-handed operators. A lid stand (1) of the present invention is a lid stand against which a lid (142) fitted in a sealed rotating container (134) of a centrifugal smearing device (130) and having a flange portion (151) protruding in a radial direction in a peripheral portion (142d) and a cylindrical scattering protective wall (160) protruding to a rear surface direction is placed by leaning, wherein: a center supporting member (10) having an upper supporting portion (12) supporting a center vicinity portion (142c) of the lid (142) on both one side and the other side is disposed at a center position; and a lateral side supporting member (20) having a lower supporting portion (22) supporting the peripheral portion (142d) of the lid (142) is disposed at positions on both sides being the one side and the other side with respect to the center supporting member (10).
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公开(公告)号：US09987638B2
公开(公告)日：2018-06-05
申请号：US14488556
申请日：2014-09-17
IPC分类号： B04B11/04 , B04B1/02 , B04B5/04 , B04B7/08 , A61M1/36 , B04B1/18 , B01D21/26 , B01D21/34 , B04B1/14
CPC分类号： B04B11/04 , A61M1/3693 , A61M1/3696 , B01D21/262 , B01D21/34 , B01D2221/10 , B04B1/02 , B04B1/14 , B04B1/18 , B04B5/0407 , B04B5/0442 , B04B7/08 , B04B2005/0485
摘要： Centrifuges are useful to, among other things, remove red blood cells from whole blood and retain platelets and other factors in a reduced volume of plasma. Platelet rich plasma (PRP) and or platelet poor plasma (PPP) can be obtained rapidly and is ready for immediate injection into the host. Embodiments may include valves, operated manually or automatically, to open ports that discharge the excess red blood cells and the excess plasma into separate receivers while retaining the platelets and other factors in the centrifuge chamber. High speeds used allow simple and small embodiments to be used at the patient's side during surgical procedures. The embodiments can also be used for the separation of liquids or slurries in other fields such as, for example, the separation of pigments or lubricants.
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