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公开(公告)号：US20230002436A1
公开(公告)日：2023-01-05
申请号：US17365361
申请日：2021-07-01
Applicant: Singular Genomics Systems, Inc.
Inventor： Ronald Graham , Surya Adhikari , Rodrigo Rodriguez , Zachary Terranova
IPC: C07H19/10 , C07H19/14 , C12Q1/6869 , C12N9/12
Abstract: Disclosed herein, inter alia, are compounds, modified nucleotides, compositions, and methods of using the same.
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公开(公告)号：US20220267603A1
公开(公告)日：2022-08-25
申请号：US17737899
申请日：2022-05-05
Applicant: Singular Genomics Systems, Inc.
Inventor： Megha Cila , Ronald Graham , Rodrigo Rodriguez
Abstract: Disclosed herein, inter alia, are silicon containing detectable compounds and methods of use thereof. In an aspect is provided a monovalent nucleotide or monovalent nucleoside covalently bound to a monovalent form of a compound described herein (e.g., wherein the R13 moiety of a compound described herein has reacted with a bioconjugate reactive group to form a bioconjugate linker thereby covalently bonding the monovalent compound to the monovalent nucleotide or monovalent nucleoside).
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公开(公告)号：US20190352508A1
公开(公告)日：2019-11-21
申请号：US16415700
申请日：2019-05-17
Applicant: SINGULAR GENOMICS SYSTEMS, INC.
Inventor： Ronald Graham , Rodrigo Rodriguez
Abstract: Disclosed herein, inter alia, are silicon containing detectable compounds and methods of use thereof.
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公开(公告)号：US20240400602A1
公开(公告)日：2024-12-05
申请号：US18791082
申请日：2024-07-31
Applicant: Singular Genomics Systems, Inc.
Inventor： Ronald Graham , Olga Adelfinskaya , Megha Cila , Rodrigo Rodriguez , Abrehet Abdu , Eli N. Glezer
IPC: C07H19/14 , C07H19/10 , C07H19/20 , C12Q1/6869 , C12Q1/6876
Abstract: Disclosed herein, inter alia, are compounds and methods of using the same for the modifying a nucleic acid molecule.
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公开(公告)号：US11878993B2
公开(公告)日：2024-01-23
申请号：US18295770
申请日：2023-04-04
Applicant: Singular Genomics Systems, Inc
Inventor： Ronald Graham , Olga Adelfinskaya , Megha Cila , Rodrigo Rodriguez , Abrehet Abdu , Eli N. Glezer
IPC: C07H19/14 , C07H19/10 , C07H19/20 , C12Q1/6869 , C12Q1/6876
CPC classification number: C07H19/14 , C07H19/10 , C07H19/20 , C12Q1/6869 , C12Q1/6876
Abstract: Disclosed herein, interalia, are compounds, compositions, and methods of using the same for the sequencing of a nucleic acid.
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Patent Agency Ranking
公开(公告)号：US11697736B2
公开(公告)日：2023-07-11
申请号：US16415700
申请日：2019-05-17
Applicant: SINGULAR GENOMICS SYSTEMS, INC.
Inventor： Ronald Graham , Rodrigo Rodriguez
CPC classification number: C09B11/24 , C07F7/083 , C07F7/0803 , C07F7/0825 , C09B69/008 , C07F7/0816 , C07H23/00
Abstract: Disclosed herein, inter alia, are silicon containing detectable compounds and methods of use thereof.
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公开(公告)号：US20230101281A1
公开(公告)日：2023-03-30
申请号：US17882448
申请日：2022-08-05
Applicant: Singular Genomics Systems, Inc.
Inventor： Megha Cila , Ronald Graham , Rodrigo Rodriguez
Abstract: Disclosed herein, inter alia, are silicon containing detectable compounds and methods of use thereof. In an aspect is provided a monovalent nucleotide or monovalent nucleoside covalently bound to a monovalent form of a compound described herein (e.g., wherein the R13 moiety of a compound described herein has reacted with a bioconjugate reactive group to form a bioconjugate linker thereby covalently bonding the monovalent compound to the monovalent nucleotide or monovalent nucleoside).
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公开(公告)号：US10738072B1
公开(公告)日：2020-08-11
申请号：US16662781
申请日：2019-10-24
Applicant: Singular Genomics Systems, Inc.
Inventor： Ronald Graham , Olga Adelfinskaya , Megha Cila , Rodrigo Rodriguez , Abrehet Abdu , Eli N. Glezer
IPC: C07H19/14 , C07H19/10 , C12Q1/68 , C12Q1/6869
Abstract: Disclosed herein, inter alia, are compounds, compositions, and methods of using the same for the sequencing of a nucleic acid.
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公开(公告)号：US12145960B2
公开(公告)日：2024-11-19
申请号：US17287255
申请日：2019-10-24
Applicant: Singular Genomics Systems, Inc.
Inventor： Ronald Graham , Olga Adelfinskaya , Megha Cila , Rodrigo Rodriguez , Abrehet Abdu , Eli N. Glezer
IPC: C07H19/14 , C07H19/10 , C07H19/20 , C12Q1/68 , C12Q1/6869 , C12Q1/6876
Abstract: Disclosed herein, interalia, are compounds, compositions, and methods of using the same for the sequencing of a nucleic acid.
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公开(公告)号：US20240279479A1
公开(公告)日：2024-08-22
申请号：US18621997
申请日：2024-03-29
Applicant: Singular Genomics Systems, Inc.
Inventor： Megha Cila , Ronald Graham , Rodrigo Rodriguez
CPC classification number: C09B62/365 , C09K11/06 , G01N33/582 , C09K2211/1018
Abstract: Disclosed herein, inter alia, are silicon containing detectable compounds and methods of use thereof. In an aspect is provided a monovalent nucleotide or monovalent nucleoside covalently bound to a monovalent form of a compound described herein (e.g., wherein the R13 moiety of a compound described herein has reacted with a bioconjugate reactive group to form a bioconjugate linker thereby covalently bonding the monovalent compound to the monovalent nucleotide or monovalent nucleoside).
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