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公开(公告)号：US20250101512A1
公开(公告)日：2025-03-27
申请号：US18949596
申请日：2024-11-15
Applicant: Singular Genomics Systems, Inc.
Inventor： Ronald Graham , Megha Cila
IPC: C12Q1/6874 , C07H19/10 , C07H19/20 , C12Q1/6806 , C12Q1/6876
Abstract: Disclosed herein, inter alia, are methods and cleavable compounds that minimize byproduct formation following cleavage in situ.
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公开(公告)号：US20220267603A1
公开(公告)日：2022-08-25
申请号：US17737899
申请日：2022-05-05
Applicant: Singular Genomics Systems, Inc.
Inventor： Megha Cila , Ronald Graham , Rodrigo Rodriguez
Abstract: Disclosed herein, inter alia, are silicon containing detectable compounds and methods of use thereof. In an aspect is provided a monovalent nucleotide or monovalent nucleoside covalently bound to a monovalent form of a compound described herein (e.g., wherein the R13 moiety of a compound described herein has reacted with a bioconjugate reactive group to form a bioconjugate linker thereby covalently bonding the monovalent compound to the monovalent nucleotide or monovalent nucleoside).
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公开(公告)号：US20240327907A1
公开(公告)日：2024-10-03
申请号：US18439062
申请日：2024-02-12
Applicant: Singular Genomics Systems, Inc.
Inventor： Ronald Graham , Megha Cila
IPC: C12Q1/6874 , C07H19/10 , C07H19/20 , C12Q1/6806 , C12Q1/6876
CPC classification number: C12Q1/6874 , C07H19/10 , C07H19/20 , C12Q1/6876 , C12Q1/6806
Abstract: Disclosed herein, inter alia, are methods and cleavable compounds that minimize byproduct formation following cleavage.
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公开(公告)号：US11970735B2
公开(公告)日：2024-04-30
申请号：US17417332
申请日：2020-01-07
Applicant: Singular Genomics Systems, Inc.
Inventor： Ronald Graham , Olga Adelfinskaya , Megha Cila , Rodrigo Rodriguez
IPC: C12Q1/6869 , C07F9/655 , C07H19/06 , C07H19/10 , C07H19/14 , C07H19/16 , C07H19/20 , C12N9/12 , C12Q1/6806
CPC classification number: C12Q1/6869 , C07F9/65515 , C07H19/06 , C07H19/10 , C07H19/14 , C07H19/16 , C07H19/20 , C12N9/1241 , C12Q1/6806 , C12Q2334/40 , C12Q2521/101 , C12Q2525/101 , C12Q2535/00
Abstract: Disclosed herein, inter alia, are compounds, compositions, and methods of use thereof for sequencing a nucleic acid.
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公开(公告)号：US20230203083A1
公开(公告)日：2023-06-29
申请号：US18178802
申请日：2023-03-06
Applicant: Singular Genomics Systems, Inc.
Inventor： Ronald Graham , Olga Adelfinskaya , Megha Cila , Rodrigo Rodriguez , Abrehet Abdu , Eli N. Glezer
IPC: C07H19/14 , C07H19/10 , C12Q1/6869 , C07H19/20 , C12Q1/6876
CPC classification number: C07H19/14 , C07H19/10 , C12Q1/6869 , C07H19/20 , C12Q1/6876
Abstract: Disclosed herein, interalia, are compounds, compositions, and methods of using the same for the sequencing of a nucleic acid.
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Patent Agency Ranking
公开(公告)号：US20200340051A1
公开(公告)日：2020-10-29
申请号：US16736493
申请日：2020-01-07
Applicant: Singular Genomics Systems, Inc.
Inventor： Ronald Graham , Olga Adelfinskaya , Megha Cila , Rodrigo Rodriguez
IPC: C12Q1/6869 , C12Q1/6806 , C07F9/655
Abstract: Disclosed herein, inter alia, are compounds, compositions, and methods of use thereof for sequencing a nucleic acid.
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公开(公告)号：US12188089B2
公开(公告)日：2025-01-07
申请号：US18439062
申请日：2024-02-12
Applicant: Singular Genomics Systems, Inc.
Inventor： Ronald Graham , Megha Cila
IPC: C12Q1/68 , C07H19/10 , C07H19/20 , C12Q1/6874 , C12Q1/6876 , C12Q1/6806
Abstract: Disclosed herein, inter alia, are methods and cleavable compounds that minimize byproduct formation following cleavage.
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公开(公告)号：US12145960B2
公开(公告)日：2024-11-19
申请号：US17287255
申请日：2019-10-24
Applicant: Singular Genomics Systems, Inc.
Inventor： Ronald Graham , Olga Adelfinskaya , Megha Cila , Rodrigo Rodriguez , Abrehet Abdu , Eli N. Glezer
IPC: C07H19/14 , C07H19/10 , C07H19/20 , C12Q1/68 , C12Q1/6869 , C12Q1/6876
Abstract: Disclosed herein, interalia, are compounds, compositions, and methods of using the same for the sequencing of a nucleic acid.
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公开(公告)号：US20240279479A1
公开(公告)日：2024-08-22
申请号：US18621997
申请日：2024-03-29
Applicant: Singular Genomics Systems, Inc.
Inventor： Megha Cila , Ronald Graham , Rodrigo Rodriguez
CPC classification number: C09B62/365 , C09K11/06 , G01N33/582 , C09K2211/1018
Abstract: Disclosed herein, inter alia, are silicon containing detectable compounds and methods of use thereof. In an aspect is provided a monovalent nucleotide or monovalent nucleoside covalently bound to a monovalent form of a compound described herein (e.g., wherein the R13 moiety of a compound described herein has reacted with a bioconjugate reactive group to form a bioconjugate linker thereby covalently bonding the monovalent compound to the monovalent nucleotide or monovalent nucleoside).
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公开(公告)号：US20240174709A1
公开(公告)日：2024-05-30
申请号：US18522886
申请日：2023-11-29
Applicant: Singular Genomics Systems, Inc.
Inventor： Ronald Graham , Olga Adelfinskaya , Megha Cila , Rodrigo Rodriguez , Abrehet Abdu , Eli N. Glezer
IPC: C07H19/14 , C07H19/10 , C07H19/20 , C12Q1/6869 , C12Q1/6876
CPC classification number: C07H19/14 , C07H19/10 , C07H19/20 , C12Q1/6869 , C12Q1/6876
Abstract: Disclosed herein, inter alia, are compounds, compositions, and methods of using the same for the sequencing of a nucleic acid.
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