公开(公告)号：US10518264B2

公开(公告)日：2019-12-31

申请号：US14221033

申请日：2014-03-20

Applicant: STMicroelectronics S.r.l.

Inventor： Sabrina Conoci ,  Maria Eloisa Castagna ,  Massimo Orazio Spata

IPC: B01L3/00 ,  C12Q1/6844

Abstract: A microreactor includes: a substrate (2; 102; 202) made of semiconductor material; a plurality of wells (5; 105; 205) separated by walls (6; 106; 206) in the substrate (2; 102; 202); a dielectric structure (7; 107; 207a, 207b) coating at least the top of the walls (6; 106; 206); a cap (3; 103; 203), bonded to the substrate (2; 102; 202) and defining a chamber (10; 110; 210) above the wells (5; 105; 205); and a biasing structure (2, 8, 13; 102, 108, 113; 202, 208a, 208b, 213), configured for setting up a voltage (VB) between the substrate (2; 102; 202) and the chamber (10; 110; 210).

公开(公告)号：US09434987B2

公开(公告)日：2016-09-06

申请号：US14543276

申请日：2014-11-17

Applicant: STMicroelectronics, S.r.l.

Inventor： Sabrina Conoci ,  Maria Eloisa Castagna ,  Massimo Orazio Spata ,  Dario Russo

IPC: B01L7/00 ,  C12Q1/68 ,  G01N21/01 ,  B01L3/00 ,  G01N21/64 ,  G06T7/00 ,  G06K9/00 ,  G01N21/25 ,  G01N21/51 ,  G01N21/03

CPC classification number: C12Q1/6851 ,  B01L3/50851 ,  B01L7/52 ,  B01L2200/10 ,  B01L2200/12 ,  B01L2300/0816 ,  B01L2300/0819 ,  B01L2300/0829 ,  B01L2300/0851 ,  B01L2300/0887 ,  B01L2300/0893 ,  B01L2300/161 ,  B01L2300/163 ,  B01L2300/168 ,  B01L2300/1827 ,  C12Q1/6825 ,  C12Q1/686 ,  G01N21/01 ,  G01N21/0303 ,  G01N21/253 ,  G01N21/51 ,  G01N21/6452 ,  G06K9/0014 ,  G06T7/0012 ,  G06T7/0014 ,  G06T2207/10064 ,  G06T2207/20024 ,  G06T2207/20061 ,  G06T2207/30072 ,  Y10T29/49885

Abstract: A cartridge for an optical analysis, including a supporting body, having a first face and a second face opposite to one another; a plurality of wells adapted to receive a biological solution to be analyzed, the wells extending in the supporting body on the first face; at least one biocompatible layer extending inside each well; an anti-reflection layer extending on the first face outside the wells; and a reflection layer extending inside each well. Methods of using same are also provided.

Abstract translation: 一种用于光学分析的盒，包括支撑体，具有彼此相对的第一面和第二面; 适于接收要分析的生物溶液的多个井，所述井在所述第一面上的所述支撑体中延伸; 在每个孔内延伸的至少一个生物相容层; 在所述孔的外部的所述第一面上延伸的防反射层; 以及在每个孔内延伸的反射层。 还提供了使用方法。

公开(公告)号：US20140291152A1

公开(公告)日：2014-10-02

申请号：US14221033

申请日：2014-03-20

Applicant: STMicroelectronics S.r.l.

Inventor： Sabrina CONOCI ,  Maria Eloisa Castagna ,  Massimo Orazio Spata

IPC: B01L3/00 ,  C12Q1/68

CPC classification number: B01L3/50273 ,  B01L3/502723 ,  B01L3/502784 ,  B01L3/5085 ,  B01L3/50851 ,  B01L2200/0642 ,  B01L2300/0864 ,  B01L2300/166 ,  B01L2400/0406 ,  B01L2400/0427 ,  C12Q1/6844

Abstract: A microreactor includes: a substrate (2; 102; 202) made of semiconductor material; a plurality of wells (5; 105; 205) separated by walls (6; 106; 206) in the substrate (2; 102; 202); a dielectric structure (7; 107; 207a, 207b) coating at least the top of the walls (6; 106; 206); a cap (3; 103; 203), bonded to the substrate (2; 102; 202) and defining a chamber (10; 110; 210) above the wells (5; 105; 205); and a biasing structure (2, 8, 13; 102, 108, 113; 202, 208a, 208b, 213), configured for setting up a voltage (VB) between the substrate (2; 102; 202) and the chamber (10; 110; 210).

Abstract translation: 微反应器包括：由半导体材料制成的衬底（2; 102; 202） 在所述衬底（2; 102; 202）中被壁（6; 106; 206）隔开的多个孔（5; 105; 205）; 涂覆至少所述壁（6; 106; 206）的顶部的电介质结构（7; 107; 207a，207b）; 盖子（3; 103; 203），其结合到所述基底（2; 102; 202）并且在所述孔（5; 105; 205）上方限定腔室（10; 110; 210） 以及偏置结构（2,8,13; 102,108,113; 202,208a，208b，213），其被配置用于在所述基板（2; 102; 202）和所述腔室（10）之间建立电压（VB） ; 110; 210）。