-
公开(公告)号：US20170130215A1
公开(公告)日：2017-05-11
申请号：US15218575
申请日：2016-07-25
IPC分类号： C12N9/24 , C12P19/18 , C12P19/02 , A61K38/47 , A61K9/00 , C11D3/386 , D21C5/00 , C09K8/62 , A23C9/13 , A23C19/04 , A23K10/14 , A23K20/189 , A23K40/10 , A23K50/10 , A23L2/52 , A23L33/18 , G01N33/573
CPC分类号： C12N9/2405 , A23C9/1322 , A23C19/04 , A23K10/14 , A23K20/189 , A23K40/10 , A23K50/10 , A23L2/52 , A23L29/10 , A23L33/18 , A23V2002/00 , A61K9/0056 , A61K38/47 , C09K8/62 , C11D3/38636 , C12N9/2437 , C12N11/02 , C12N11/14 , C12N11/16 , C12P7/10 , C12P19/02 , C12P19/18 , C12Y302/01004 , D21C1/00 , D21C5/005 , G01N33/53 , G01N33/573 , G01N2333/924 , G01N2500/00 , Y02E50/16 , Y02E50/17
摘要： The invention relates to polypeptides having glucanase, e.g., endoglucanase, mannanase, xylanase activity or a combination of these activities, and polynucleotides encoding them. In one aspect, the glucanase activity is an endoglucanase activity (e.g., endo-1,4-beta-D-glucan 4-glucano hydrolase activity) and comprises hydrolysis of 1,4 -beta-D-glycosidic linkages in cellulose, cellulose derivatives (e.g., carboxy methyl cellulose and hydroxy ethyl cellulose) lichenin, beta-1,4 bonds in mixed beta-1,3 glucans, such as cereal beta-D-glucans or xyloglucans and other plant material containing cellulosic parts. In addition, methods of designing new enzymes and methods of use thereof are also provided. In alternative aspects, the new glucanases e.g., endoglucanases, mannanases, xylanases have increased activity and stability at increased pH and temperature.
-
2.发明授权Glucanases, nucleic acids encoding them and methods for making and using them 有权葡聚糖酶，编码它们的核酸和制备和使用它们的方法公开(公告)号：US09422536B2
公开(公告)日：2016-08-23
申请号：US14019460
申请日：2013-09-05
IPC分类号： C12N11/14 , C12N9/24 , A23K1/165 , A23C9/13 , A23K1/00 , A23K1/18 , C12N9/42 , A23C19/04 , A23L1/305 , A23L2/52 , C12N11/02 , C12N11/16 , C12P7/10 , D21C1/00 , G01N33/53 , G01N33/573
CPC分类号： C12N9/2405 , A23C9/1322 , A23C19/04 , A23K10/14 , A23K20/189 , A23K40/10 , A23K50/10 , A23L2/52 , A23L29/10 , A23L33/18 , A23V2002/00 , A61K9/0056 , A61K38/47 , C09K8/62 , C11D3/38636 , C12N9/2437 , C12N11/02 , C12N11/14 , C12N11/16 , C12P7/10 , C12P19/02 , C12P19/18 , C12Y302/01004 , D21C1/00 , D21C5/005 , G01N33/53 , G01N33/573 , G01N2333/924 , G01N2500/00 , Y02E50/16 , Y02E50/17
摘要： The invention relates to polypeptides having glucanase, e.g., endoglucanase, mannanase, xylanase activity or a combination of these activities, and polynucleotides encoding them. In one aspect, the glucanase activity is an endoglucanase activity (e.g., endo-1,4-beta-D-glucan 4-glucano hydrolase activity) and comprises hydrolysis of 1,4-beta-D-glycosidic linkages in cellulose, cellulose derivatives (e.g., carboxy methyl cellulose and hydroxy ethyl cellulose) lichenin, beta-1,4 bonds in mixed beta-1,3 glucans, such as cereal beta-D-glucans or xyloglucans and other plant material containing cellulosic parts. In addition, methods of designing new enzymes and methods of use thereof are also provided. In alternative aspects, the new glucanases e.g., endoglucanases, mannanases, xylanases have increased activity and stability at increased pH and temperature.
摘要翻译： 本发明涉及具有葡聚糖酶的多肽，例如内切葡聚糖酶，甘露聚糖酶，木聚糖酶活性或这些活性的组合，以及编码它们的多核苷酸。 一方面，葡聚糖酶活性是内切葡聚糖酶活性（例如内切-1,4-β-D-葡聚糖4-葡聚糖水解酶活性），并且包括在纤维素，纤维素衍生物中水解1,4-β-D-糖苷键 （例如，羧甲基纤维素和羟乙基纤维素）地衣淀粉，混合的β-1,3葡聚糖中的β-1,4键，例如谷类β-D-葡聚糖或木葡聚糖和含有纤维素部分的其它植物材料。 此外，还提供了设计新酶的方法及其使用方法。 在替代方面，新葡聚糖酶例如内切葡聚糖酶，甘露聚糖酶，木聚糖酶在增加的pH和温度下具有增加的活性和稳定性。
-
3.发明申请GLUCANASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM 有权葡萄糖，编码它们的核酸及其制备和使用它们的方法公开(公告)号：US20140199705A1
公开(公告)日：2014-07-17
申请号：US14019460
申请日：2013-09-05
IPC分类号： C12N9/24 , G01N33/573 , C12P7/10 , C12N11/02 , C12N11/14 , A23C9/13 , D21C1/00 , A23L1/305 , A23L2/52 , A23K1/165 , A23C19/04 , G01N33/53 , C12N11/16
CPC分类号： C12N9/2405 , A23C9/1322 , A23C19/04 , A23K10/14 , A23K20/189 , A23K40/10 , A23K50/10 , A23L2/52 , A23L29/10 , A23L33/18 , A23V2002/00 , A61K9/0056 , A61K38/47 , C09K8/62 , C11D3/38636 , C12N9/2437 , C12N11/02 , C12N11/14 , C12N11/16 , C12P7/10 , C12P19/02 , C12P19/18 , C12Y302/01004 , D21C1/00 , D21C5/005 , G01N33/53 , G01N33/573 , G01N2333/924 , G01N2500/00 , Y02E50/16 , Y02E50/17
摘要： The invention relates to polypeptides having glucanase, e.g., endoglucanase, mannanase, xylanase activity or a combination of these activities, and polynucleotides encoding them. In one aspect, the glucanase activity is an endoglucanase activity (e.g., endo-1,4-beta-D-glucan 4-glucano hydrolase activity) and comprises hydrolysis of 1,4-beta-D-glycosidic linkages in cellulose, cellulose derivatives (e.g., carboxy methyl cellulose and hydroxy ethyl cellulose) lichenin, beta-1,4 bonds in mixed beta-1,3 glucans, such as cereal beta-D-glucans or xyloglucans and other plant material containing cellulosic parts. In addition, methods of designing new enzymes and methods of use thereof are also provided. In alternative aspects, the new glucanases e.g., endoglucanases, mannanases, xylanases have increased activity and stability at increased pH and temperature.
摘要翻译： 本发明涉及具有葡聚糖酶的多肽，例如内切葡聚糖酶，甘露聚糖酶，木聚糖酶活性或这些活性的组合，以及编码它们的多核苷酸。 一方面，葡聚糖酶活性是内切葡聚糖酶活性（例如内切-1,4-β-D-葡聚糖4-葡聚糖水解酶活性），并且包括在纤维素，纤维素衍生物中水解1,4-β-D-糖苷键 （例如，羧甲基纤维素和羟乙基纤维素）地衣淀粉，混合的β-1,3葡聚糖中的β-1,4键，例如谷类β-D-葡聚糖或木葡聚糖和含有纤维素部分的其它植物材料。 此外，还提供了设计新酶的方法及其使用方法。 在替代方面，新葡聚糖酶例如内切葡聚糖酶，甘露聚糖酶，木聚糖酶在增加的pH和温度下具有增加的活性和稳定性。
-
公开(公告)号：US20150329880A1
公开(公告)日：2015-11-19
申请号：US14816992
申请日：2015-08-03
发明人： Justin T. Stege , Alexander Varvak , John Poland , Chris S. Lyon , Shaun Healey , Peter Luginbuhl
CPC分类号： C12P7/14 , C12N9/2437 , C12P7/10 , C12P19/02 , C12P19/14 , C12Y302/01091 , Y02E50/16 , Y02E50/17
摘要： The present disclosure relates to variant CBH I polypeptides that have reduced product inhibition, and compositions, e.g., cellulase compositions, comprising variant CBH I polypeptides. The variant CBH I polypeptides and related compositions can be used in variety of agricultural and industrial applications. The present disclosure further relates to nucleic acids encoding variant CBH I polypeptides and host cells that recombinantly express the variant CBH I polypeptides.
摘要翻译： 本公开涉及具有降低的产物抑制的变体CBH I多肽，以及包含变体CBH I多肽的组合物，例如纤维素酶组合物。 变体CBH I多肽和相关组合物可用于各种农业和工业应用。 本公开还涉及编码变体CBH I多肽的核酸和重组表达变体CBH I多肽的宿主细胞。
-
5.发明申请XYLANASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM 审中-公开XYLANASES，核酸编码它们及其制备和使用方法公开(公告)号：US20150139977A1
公开(公告)日：2015-05-21
申请号：US14521317
申请日：2014-10-22
发明人： David Weiner , David Blum , Alexander Varvak , Shaun Healey , Kristine Chang , Geoff Hazlewood , Thomas Todaro , Grace Desantis , Hwai Chang , Connie Jo Hansen , Scott W. Beaver , Thomas Woodward , Charles Hancock
IPC分类号： C12N9/24 , C12P19/02 , C12P19/14 , D21H17/00 , A23K1/16 , D21C9/10 , D06L3/14 , D06L3/11 , A23L1/09 , A23K1/00 , C12N9/42 , D21C3/00
CPC分类号： C12N9/248 , A23K10/12 , A23K20/163 , A23L5/00 , A23L7/00 , A23L29/30 , A23L31/00 , A23L31/10 , A23L33/125 , A23V2002/00 , C12N9/2405 , C12N9/2437 , C12N9/2482 , C12N9/2488 , C12N9/2494 , C12P19/02 , C12P19/14 , C12Y302/01008 , D06L4/40 , D06L4/70 , D21C3/003 , D21C9/10 , D21H17/005 , Y02E50/16
摘要： The invention relates to enzymes having xylanase, mannanase and/or glucanase activity, e.g., catalyzing hydrolysis of internal β-1,4-xylosidic linkages or endo-β-1,4-glucanase linkages; and/or degrading a linear polysaccharide beta-1,4-xylan into xylose. Thus, the invention provides methods and processes for breaking down hemicellulose, which is a major component of the cell wall of plants, including methods and processes for hydrolyzing hemicelluloses in any plant or wood or wood product, wood waste, paper pulp, paper product or paper waste or byproduct. In addition, methods of designing new xylanases, mannanases and/or glucanases and methods of use thereof are also provided. The xylanases, mannanases and/or glucanases have increased activity and stability at increased pH and temperature.
摘要翻译： 本发明涉及具有木聚糖酶，甘露聚糖酶和/或葡聚糖酶活性的酶，例如催化内部-1,4-木糖苷键或内切-1,4-葡聚糖酶键的水解; 和/或将线性多糖β-1,4-木聚糖降解成木糖。 因此，本发明提供了分解作为植物细胞壁的主要成分的半纤维素的方法和方法，包括在任何植物或木材或木制品，木材废料，纸浆，纸制品中水解半纤维素的方法和方法， 废纸或副产品。 此外，还提供了设计新的木聚糖酶，甘露聚糖酶和/或葡聚糖酶的方法及其使用方法。 木聚糖酶，甘露聚糖酶和/或葡聚糖酶在增加的pH和温度下具有增加的活性和稳定性。
-
公开(公告)号：US10329549B2
公开(公告)日：2019-06-25
申请号：US14229633
申请日：2014-03-28
发明人： Brian Steer , Shaun Healey , Alireza Esteghlalian , Stacy Marie Miles , Kenneth Barrett , Rene Quadt
IPC分类号： C12N9/42 , C12N9/24 , C09K8/035 , C09K8/52 , C09K8/68 , C09K8/74 , C09K8/80 , C09K8/90 , C12P19/02 , C12P19/14 , E21B43/26 , A23K20/147 , A23L33/18 , G16B30/00
摘要： The invention relates to polypeptides having glucanase, e.g., endoglucanase, mannanase, xylanase activity or a combination of these activities, and polynucleotides encoding them. In one aspect, the glucanase activity is an endoglucanase activity (e.g., endo-1,4-beta-D-glucan 4-glucano hydrolase activity) and comprises hydrolysis of 1,4-beta-D-glycosidic linkages in cellulose, cellulose derivatives (e.g., carboxy methyl cellulose and hydroxy ethyl cellulose) lichenin, beta-1,4 bonds in mixed beta-1,3 glucans, such as cereal beta-D-glucans or xyloglucans and other plant material containing cellulosic parts. In addition, methods of designing new enzymes and methods of use thereof are also provided. In alternative aspects, the new glucanases e.g., endoglucanases, mannanases, xylanases have increased activity and stability, including thermotolerance or thermostability, at increased or decreased pHs and temperatures.
-
公开(公告)号：US09765319B2
公开(公告)日：2017-09-19
申请号：US13835743
申请日：2013-03-15
发明人： Brian Steer , Walter Callen , Shaun Healey , Geoff Hazlewood , Di Wu , David Blum , Alireza Esteghlalian
CPC分类号： C12N9/248 , A01K2217/05 , C07K2319/00 , C07K2319/02 , C12N9/2434 , C12N9/2482 , C12P19/14 , C12Y302/01008 , D21C5/005 , D21H17/005 , Y02E50/16 , Y02E50/17
摘要： The invention relates to xylanases and to polynucleotides encoding the xylanases. In addition, methods of designing new xylanases and methods of use thereof are also provided. The xylanases have increased activity and stability at increased pH and temperature.
-
8.再颁专利Xylanases, nucleic acids encoding them and methods for making and using them 有权木聚糖酶，编码它们的核酸以及制备和使用它们的方法公开(公告)号：USRE45660E1
公开(公告)日：2015-09-01
申请号：US14064032
申请日：2013-10-25
发明人： David Weiner , David Blum , Alexander Varvak , Shaun Healey , Kristine Chang , Geoff Hazlewood , Thomas Todaro , Grace Desantis , Hwai Chang , Connie Jo Hansen , Scott W. Beaver , Thomas Woodward , Charles Hancock
IPC分类号： C12N9/24 , C12P21/06 , C12N1/20 , C12N1/15 , C12N1/16 , C12N1/19 , C12N15/70 , C07H21/04 , A01H5/00
CPC分类号： C12N9/248 , A23K10/12 , A23K20/163 , A23L5/00 , A23L7/00 , A23L29/30 , A23L31/00 , A23L31/10 , A23L33/125 , A23V2002/00 , C12N9/2405 , C12N9/2437 , C12N9/2482 , C12N9/2488 , C12N9/2494 , C12P19/02 , C12P19/14 , C12Y302/01008 , D06L4/40 , D06L4/70 , D21C3/003 , D21C9/10 , D21H17/005 , Y02E50/16
摘要： The invention relates to enzymes having xylanase, mannanase and/or glucanase activity, e.g., catalyzing hydrolysis of internal β-1,4-xylosidic linkages or endo-β-1,4-ghicanase linkages; and/or degrading a linear polysaccharide beta-1,4-xylan into xylose. Thus, the invention provides methods and processes for breaking down hemicellulose, which is a major component of the cell wall of plants, including methods and processes for hydrolyzing hemicelluloses in any plant or wood or wood product, wood waste, paper pulp, paper product or paper waste or byproduct. In addition, methods of designing new xylanases, mannanases and/or glucanases and methods of use thereof are also provided. The xylanases, mannanases and/or glucanases have increased activity and stability at increased pH and temperature.
摘要翻译： 本发明涉及具有木聚糖酶，甘露聚糖酶和/或葡聚糖酶活性的酶，例如催化内部-1,4-木糖苷键或内切-1,4-羟基化酶键的水解; 和/或将线性多糖β-1,4-木聚糖降解成木糖。 因此，本发明提供了分解作为植物细胞壁的主要成分的半纤维素的方法和方法，包括在任何植物或木材或木制品，木材废料，纸浆，纸制品中水解半纤维素的方法和方法， 废纸或副产品。 此外，还提供了设计新的木聚糖酶，甘露聚糖酶和/或葡聚糖酶的方法及其使用方法。 木聚糖酶，甘露聚糖酶和/或葡聚糖酶在增加的pH和温度下具有增加的活性和稳定性。
-
9.发明申请Glucanases, Nucleic Acids Encoding Them and Methods for Making and Using Them 审中-公开葡聚糖酶，编码它们的核酸及其制备和使用方法公开(公告)号：US20140295523A1
公开(公告)日：2014-10-02
申请号：US14229633
申请日：2014-03-28
发明人： Brian Steer , Shaun Healey , Alireza Esteghlalian , Stacy Marie Miles , Kenneth Barrett , Rene Quadt
CPC分类号： C12N9/2437 , A23K20/147 , A23L33/18 , C09K8/035 , C09K8/52 , C09K8/68 , C09K8/74 , C09K8/805 , C09K8/90 , C09K2208/24 , C12N9/2405 , C12P19/02 , C12P19/14 , C12Y302/01004 , C12Y302/01006 , C12Y302/01008 , C12Y302/01039 , E21B43/26 , G16B30/00 , Y02E50/17
摘要： The invention relates to polypeptides having glucanase, e.g., endoglucanase, mannanase, xylanase activity or a combination of these activities, and polynucleotides encoding them. In one aspect, the glucanase activity is an endoglucanase activity (e.g., endo-1,4-beta-D-glucan 4-glucano hydrolase activity) and comprises hydrolysis of 1,4-beta-D-glycosidic linkages in cellulose, cellulose derivatives (e.g., carboxy methyl cellulose and hydroxy ethyl cellulose) lichenin, beta-1,4 bonds in mixed beta-1,3 glucans, such as cereal beta-D-glucans or xyloglucans and other plant material containing cellulosic parts. In addition, methods of designing new enzymes and methods of use thereof are also provided. In alternative aspects, the new glucanases e.g., endoglucanases, mannanases, xylanases have increased activity and stability, including thermotolerance or thermostability, at increased or decreased pHs and temperatures.
摘要翻译： 本发明涉及具有葡聚糖酶的多肽，例如内切葡聚糖酶，甘露聚糖酶，木聚糖酶活性或这些活性的组合，以及编码它们的多核苷酸。 一方面，葡聚糖酶活性是内切葡聚糖酶活性（例如内切-1,4-β-D-葡聚糖4-葡聚糖水解酶活性），并且包括在纤维素，纤维素衍生物中水解1,4-β-D-糖苷键 （例如，羧甲基纤维素和羟乙基纤维素）地衣淀粉，混合的β-1,3葡聚糖中的β-1,4键，例如谷类β-D-葡聚糖或木葡聚糖和含有纤维素部分的其它植物材料。 此外，还提供了设计新酶的方法及其使用方法。 在替代方面，新葡聚糖酶例如内切葡聚糖酶，甘露聚糖酶，木聚糖酶在增加或降低的pH和温度下具有增加的活性和稳定性，包括耐热性或热稳定性。
-
-
-
-
-
-
-
-
搜索结果
9 条记录 (耗时 0.07 秒)
