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27 条记录 (耗时 0.027 秒)

    Devices and methods for interstitial injection of biologic agents into tissue
    1.
    发明申请
    Devices and methods for interstitial injection of biologic agents into tissue 有权
    将生物制剂间插注入组织的装置和方法

    公开(公告)号：US20070049863A1

    公开(公告)日：2007-03-01

    申请号：US11545197

    申请日：2006-10-10

    申请人： Scott Jahns ,  Gary Oehme ,  Matthew Bonner ,  James Keogh

    发明人： Scott Jahns ,  Gary Oehme ,  Matthew Bonner ,  James Keogh

    IPC分类号： A61M31/00

    CPC分类号： A61B17/3478 ,  A61B17/00234 ,  A61B17/205 ,  A61B2017/00247 ,  A61B2017/00876 ,  A61B2017/2936 ,  A61B2017/2943 ,  A61B2017/306 ,  A61B2018/00392 ,  A61B2090/034 ,  A61M5/32 ,  A61M2025/0086 ,  A61M2025/0087

    摘要： Apparatus and methods for injecting biological agents into tissue. Devices are provided having elongate shafts and distal injection heads for transversely driving needles into tissue and injecting medical agents into the tissue through the needles. A longitudinal force directed along the shaft can be translated to a needle driving force transverse to the shaft. Some devices provide controllably variable needle penetration depth. Devices include mechanical needle drivers utilizing four link pantographs, rack and pinions, and drive yokes for driving a first needle bearing body toward a second tissue contacting body. Other devices include inflatable members for driving and retracting needles. Still other devices include magnets for biasing the needles in extended and/or retracted positions. The invention includes minimally invasive methods for epicardially injecting cardiocyte precursor cells into infarct myocardial tissue.

    摘要翻译： 将生物制剂注入组织的装置和方法。 设备具有细长的轴和远端注射头，用于将针横向驱动到组织中，并通过针将药剂注射到组织中。 沿着轴引导的纵向力可以平移到与轴垂直的针驱动力​​。 一些装置提供可控的可变针穿透深度。 设备包括利用四个连杆缩放仪，齿条和小齿轮的机械针驱动器和用于将第一滚针轴承体朝向第二组织接触体驱动的驱动轭。 其他装置包括用于驱动和缩回针的可充气构件。 还有其它装置包括用于在延伸和/或缩回位置偏置针的磁体。 本发明包括用心外膜将心脏细胞前体细胞注入梗死心肌组织的微创方法。

    Cardiac mapping instrument with shapeable electrode
    3.
    发明申请
    Cardiac mapping instrument with shapeable electrode 审中-公开
    具有可塑电极的心脏测绘仪

    公开(公告)号：US20070043397A1

    公开(公告)日：2007-02-22

    申请号：US11586112

    申请日：2006-10-25

    申请人： Jon Ocel ,  Roderick Briscoe ,  David Francischelli ,  Scott Jahns ,  James Keogh ,  Katherine Jolly ,  Matthew Bonner

    发明人： Jon Ocel ,  Roderick Briscoe ,  David Francischelli ,  Scott Jahns ,  James Keogh ,  Katherine Jolly ,  Matthew Bonner

    IPC分类号： A61N1/362

    CPC分类号： A61B5/042 ,  A61B5/7475 ,  A61B18/14 ,  A61B2017/2927 ,  A61B2018/1472 ,  A61N1/056

    摘要： An instrument including an elongated shaft and a non-conductive handle is disclosed. The shaft defines a proximal section and a distal section. The distal section forms an electrically conductive tip. Further, the shaft is adapted to be transitionable from a straight state to a first bent state. The shaft is capable of independently maintaining the distinct shapes associated with the straight state and the first bent state. The handle is rigidly coupled to the proximal section of the shaft. The instrument is useful for epicardial pacing and/or mapping of the heart for temporary pacing on a beating heart, for optimizing the placement of ventricular leads for the treatment of patients with congestive heart failure and ventricular dysynchrony and/or for use in surgical ablation procedures.

    摘要翻译： 公开了一种包括细长轴和非导电手柄的仪器。 轴限定近端部分和远端部分。 远侧部分形成导电尖端。 此外，轴适于从直状态转变到第一弯曲状态。 轴能够独立地保持与直线状态和第一弯曲状态相关联的不同形状。 手柄刚性地联接到轴的近端部分。 该仪器可用于心脏起搏和/或心脏在心脏跳动中临时起搏的作用，以优化用于治疗患有充血性心力衰竭和心室异常不适和/或用于外科手术切除手术的患者的心室导线的位置 。

    Method and system for monitoring and controlling systemic and pulmonary circulation during a medical procedure
    8.
    发明申请
    Method and system for monitoring and controlling systemic and pulmonary circulation during a medical procedure 审中-公开
    在医疗过程中监测和控制全身和肺循环的方法和系统

    公开(公告)号：US20050096707A1

    公开(公告)日：2005-05-05

    申请号：US11000262

    申请日：2004-11-30

    申请人： Michael Hill ,  Scott Jahns ,  James Keogh

    发明人： Michael Hill ,  Scott Jahns ,  James Keogh

    IPC分类号： A61N1/36 ,  A61N1/38 ,  A61N1/365

    CPC分类号： A61N1/36114 ,  A61N1/385

    摘要： A method of performing a medical procedure, such as surgery, is provided. The system comprises a sensor to sense a biological characteristic, such as a chemical, physical or physiological characteristic of a bodily tissue or fluid. The method also comprises a nerve stimulator in communication with the sensor to inhibit beating of a heart when the sensor senses the biological characteristic at a first value; and a cardiac stimulator in communication with the sensor to stimulate beating of the heart when the sensor senses the biological characteristic at a second value.

    摘要翻译： 提供了一种执行诸如手术的医疗程序的方法。 该系统包括用于感测身体组织或液体的生物学特性，例如化学，物理或生理特征的传感器。 所述方法还包括与所述传感器通信的神经刺激器，以在所述传感器以第一值感测所述生物学特性时抑制心脏跳动; 以及与所述传感器通信的心脏刺激器，以在所述传感器以第二值感测所述生物特征时刺激所述心跳。

    Method and system for nerve stimulation and cardiac sensing prior to and during a medical procedure
    9.
    发明申请
    Method and system for nerve stimulation and cardiac sensing prior to and during a medical procedure 审中-公开
    在医疗过程之前和期间神经刺激和心脏感知的方法和系统

    公开(公告)号：US20070208388A1

    公开(公告)日：2007-09-06

    申请号：US11796663

    申请日：2007-04-27

    申请人： Scott Jahns ,  Michael Hill ,  James Keogh

    发明人： Scott Jahns ,  Michael Hill ,  James Keogh

    IPC分类号： A61N1/362

    CPC分类号： A61N1/36114 ,  A61N1/362 ,  A61N1/385

    摘要： A method of performing a medical procedure, such as surgery, is provided. A nerve is stimulated in order to adjust the beating of the heart to a first condition, such as a stopped or slowed condition. The medical procedure is performed on the heart or another organ. The stimulation of the nerve is stopped in order to adjust the beating of the heart to a second condition, such as a beating condition. The heart itself may also be stimulated to a beating condition, such as by pacing. The stimulation of the nerve may be continued in order to allow the medical procedure to be continued. A sensor to sense a characteristic of a fluid or tissue, such as an impending contraction, may be also used during the medical procedure. Systems and devices for performing the medical procedure are also provided.

    摘要翻译： 提供了一种执行诸如手术的医疗程序的方法。 刺激神经以将心脏的跳动调节到第一状态，例如停止或减缓的状态。 医疗程序在心脏或另一个器官上进行。 停止对神经的刺激，以便将心脏的跳动调节到第二状态，例如打浆状态。 心脏本身也可能被刺激到跳动状态，例如通过起搏。 可以继续刺激神经以允许继续医疗手术。 也可以在医疗过程中使用用于感测流体或组织的特征的传感器，例如即将收缩的收缩。 还提供用于执行医疗程序的系统和设备。

    Electrosurgical methods and apparatus for making precise incisions in body vessels
    10.
    发明申请
    Electrosurgical methods and apparatus for making precise incisions in body vessels 有权
    电动手术方法和装置，用于精确切开体内血管

    公开(公告)号：US20070123854A1

    公开(公告)日：2007-05-31

    申请号：US11698332

    申请日：2007-01-26

    申请人： Cynthia Clague ,  Philip Haarstad ,  Scott Jahns ,  James Keogh ,  Christopher Olig ,  Raymond Usher

    发明人： Cynthia Clague ,  Philip Haarstad ,  Scott Jahns ,  James Keogh ,  Christopher Olig ,  Raymond Usher

    IPC分类号： A61B18/14

    CPC分类号： A61B18/14 ,  A61B18/1482 ,  A61B2018/00386 ,  A61B2018/1407 ,  A61B2090/034 ,  A61B2090/036

    摘要： Methods and apparatus employed in surgery involving making precise incisions in vessels of the body, particularly cardiac blood vessels in coronary revascularization procedures conducted on the stopped or beating heart are disclosed. Such incisions are created by applying an elongated electrosurgical cutting electrode to the outer surface of the vessel wall in substantially parallel alignment with the body vessel axis, the elongated electrosurgical cutting electrode having a predetermined cutting electrode length exceeding the cutting electrode width. RF energy is applied between the electrosurgical cutting electrode and the ground electrode at an energy level and for a duration sufficient to cut an elongated slit through the vessel wall where the elongated electrosurgical cutting electrode is applied to the surface of the vessel wall.

    摘要翻译： 公开了涉及在停止或跳动的心脏进行的冠状动脉血运重建手术中精确切开身体血管，特别是心脏血管的手术方法和装置。 这种切口是通过将细长的电外科切割电极以与体血管轴线基本平行对准的方式将细长的电外科切割电极施加到血管壁的外表面而形成的，细长的电外切割电极具有超过切割电极宽度的预定切割电极长度。 RF能量在电外科切割电极和接地电极之间以能量水平施加，持续时间足以切割通过血管壁的细长狭缝，其中细长的电外科切割电极被施加到血管壁的表面。