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    Method of preparing a muscadine pomace extract
    5.
    发明授权
    Method of preparing a muscadine pomace extract 有权
    制备麝香葡萄果渣提取物的方法

    公开(公告)号：US09173916B2

    公开(公告)日：2015-11-03

    申请号：US13828707

    申请日：2013-03-14

    申请人： Shaklee Corporation

    发明人： Teodoro T. Ianiro ,  Laurel A. Fisher ,  William J. Mergens

    IPC分类号： A61K36/87 ,  A61K31/065 ,  A61K31/352 ,  A23L1/30 ,  A61K31/05

    CPC分类号： A61K36/87 ,  A23L33/105 ,  A61K31/05 ,  A61K31/065 ,  A61K31/352 ,  A61K2300/00

    摘要： Muscadine grape extracts are disclosed that have antioxidant properties. The extracts are a mixture of extracts from bronze and purple muscadine grapes that unexpectedly increase the solubility of ellagic acid in the mixture. Solvent extracts are obtained in some examples by water extracting the pomaces of the grapes from which the juice has substantially been removed. Further surprising increases in ellagic acid solubility can also be obtained by adding an additional source of anthocyanins to the extract, for example by including in the composition an extract of whole purple muscadine grapes from which substantial amounts of the juice have not been removed. Other additional sources of anthocyanins include blueberries, blackberries and raspberries; the additional source of anthocyanins can be obtained from a fruit processing waste stream to increase the efficiency of the production process.

    摘要翻译： 公开了具有抗氧化性质的麝香葡萄提取物。 提取物是来自青铜和紫色麝香葡萄葡萄的提取物的混合物，其意外地增加鞣花酸在混合物中的溶解度。 在一些实例中通过水提取葡萄的果渣获得溶剂提取物，其中果汁基本上已被除去。 还可以通过向提取物中加入额外的花青素来源，例如通过在组合物中包含未被除去大量的汁的全部紫色麝香葡萄葡萄的提取物，可以获得鞣花酸溶解度的进一步惊人的增加。 其他额外的花青素来源包括蓝莓，黑莓和覆盆子; 可以从水果加工废料流中获得额外的花青素来源，以提高生产过程的效率。

    Muscadine compositions with improved anti-oxidant activity
    6.
    发明授权
    Muscadine compositions with improved anti-oxidant activity 有权
    具有改善的抗氧化活性的麝香葡萄甙组合物

    公开(公告)号：US08911804B2

    公开(公告)日：2014-12-16

    申请号：US14034375

    申请日：2013-09-23

    申请人： Shaklee Corporation

    发明人： Laurel A. Fisher ,  Teodoro T. Ianiro ,  William J. Mergens ,  Nasrin Zamanian

    IPC分类号： A61K36/87 ,  A61K31/352 ,  A61K31/7048 ,  A23L1/30 ,  A61K31/05

    CPC分类号： A61K31/7048 ,  A23L33/105 ,  A23V2002/00 ,  A61K31/05 ,  A61K31/352 ,  A61K36/87 ,  A23V2200/302 ,  A23V2250/21

    摘要： Disclosed is a composition for use as an antioxidant, such as for use as an anti-aging supplement. The composition can include a muscadine (Vitis rotundifolia) pomace extract having a polyphenol content of at least 2% and trans-resveratrol from a source other than muscadine with a minimum purity of at least 5%. In an example, the ratio of muscadine pomace extract polyphenols to trans-resveratrol is in the range of 0.1/1 to 10/1 (weight to weight), thereby providing a composition with antioxidant activity. Also disclosed are methods of producing antioxidant compositions. These methods can include combining a muscadine pomace extract having a polyphenol content of at least 2% and resveratrol from a source other than muscadine with a minimum purity of at least 5% at a ratio in the range of 0.1/1 to 10/1 (weight to weight), thereby providing a composition with antioxidant activity.

    摘要翻译： 公开了用作抗氧化剂的组合物，例如用作抗老化补充剂。 该组合物可以包含具有至少2％的多酚含量的麝香葡萄（Vitis rotundifolia）果渣提取物和来自除麝香酮以外的来源的反式白藜芦醇，其最低纯度至少为5％。 在一个实例中，麝香葡萄果渣提取物多酚与反式白藜芦醇的比例在0.1 / 1-10 / 1（重量/重量）的范围内，从而提供具有抗氧化活性的组合物。 还公开了生产抗氧化剂组合物的方法。 这些方法可以包括将具有至少2％的多酚含量的麝香葡萄果渣提取物与来自麝香酮以外的来源的白藜芦醇组合，其中最低纯度至少为5％，比例为0.1 / 1至10/1（ 重量），从而提供具有抗氧化活性的组合物。

    MUSCADINE COMPOSITIONS WITH IMPROVED ANTI-OXIDANT ACTIVITY
    7.
    发明申请
    MUSCADINE COMPOSITIONS WITH IMPROVED ANTI-OXIDANT ACTIVITY 有权
    具有改善的抗氧化活性的MUSCADINE组合物

    公开(公告)号：US20140018311A1

    公开(公告)日：2014-01-16

    申请号：US14034375

    申请日：2013-09-23

    申请人： Shaklee Corporation

    发明人： Laurel A. Fisher ,  Teodoro T. Ianiro ,  William J. Mergens ,  Nasrin Zamanian

    IPC分类号： A61K31/7048 ,  A61K31/352 ,  A61K31/05

    CPC分类号： A61K31/7048 ,  A23L33/105 ,  A23V2002/00 ,  A61K31/05 ,  A61K31/352 ,  A61K36/87 ,  A23V2200/302 ,  A23V2250/21

    摘要： Disclosed is a composition for use as an antioxidant, such as for use as an anti-aging supplement. The composition can include a muscadine (Vitis rotundifolia) pomace extract having a polyphenol content of at least 2% and trans-resveratrol from a source other than muscadine with a minimum purity of at least 5%. In an example, the ratio of muscadine pomace extract polyphenols to trans-resveratrol is in the range of 0.1/1 to 10/1 (weight to weight), thereby providing a composition with antioxidant activity. Also disclosed are methods of producing antioxidant compositions. These methods can include combining a muscadine pomace extract having a polyphenol content of at least 2% and resveratrol from a source other than muscadine with a minimum purity of at least 5% at a ratio in the range of 0.1/1 to 10/1 (weight to weight), thereby providing a composition with antioxidant activity.

    摘要翻译： 公开了用作抗氧化剂的组合物，例如用作抗老化补充剂。 该组合物可以包含具有至少2％的多酚含量的麝香葡萄（Vitis rotundifolia）果渣提取物和来自除麝香酮以外的来源的反式白藜芦醇，其最低纯度至少为5％。 在一个实例中，麝香葡萄果渣提取物多酚与反式白藜芦醇的比例在0.1 / 1-10 / 1（重量/重量）的范围内，从而提供具有抗氧化活性的组合物。 还公开了生产抗氧化剂组合物的方法。 这些方法可以包括将具有至少2％的多酚含量的麝香葡萄果渣提取物与来自麝香酮以外的来源的白藜芦醇组合，其中最低纯度至少为5％，比例范围为0.1 / 1至10/1（ 重量），从而提供具有抗氧化活性的组合物。

    METHOD OF PREPARING A MUSCADINE POMACE EXTRACT
    8.
    发明申请
    METHOD OF PREPARING A MUSCADINE POMACE EXTRACT 有权
    制备MUSCADINE POMACE提取物的方法

    公开(公告)号：US20130202725A1

    公开(公告)日：2013-08-08

    申请号：US13828707

    申请日：2013-03-14

    申请人： SHAKLEE CORPORATION

    发明人： Teodoro T. Ianiro ,  Laurel A. Fisher ,  William J. Mergens

    IPC分类号： A61K36/87 ,  A61K31/352 ,  A23L1/30 ,  A61K31/065

    CPC分类号： A61K36/87 ,  A23L33/105 ,  A61K31/05 ,  A61K31/065 ,  A61K31/352 ,  A61K2300/00

    摘要： Muscadine grape extracts are disclosed that have antioxidant properties. The extracts are a mixture of extracts from bronze and purple muscadine grapes that unexpectedly increase the solubility of ellagic acid in the mixture. Solvent extracts are obtained in some examples by water extracting the pomaces of the grapes from which the juice has substantially been removed. Further surprising increases in ellagic acid solubility can also be obtained by adding an additional source of anthocyanins to the extract, for example by including in the composition an extract of whole purple muscadine grapes from which substantial amounts of the juice have not been removed. Other additional sources of anthocyanins include blueberries, blackberries and raspberries; the additional source of anthocyanins can be obtained from a fruit processing waste stream to increase the efficiency of the production process.

    摘要翻译： 公开了具有抗氧化性质的麝香葡萄提取物。 提取物是来自青铜和紫色麝香葡萄葡萄的提取物的混合物，其意外地增加鞣花酸在混合物中的溶解度。 在一些实例中通过水提取葡萄的果渣获得溶剂提取物，其中果汁基本上已被除去。 还可以通过向提取物中加入额外的花青素来源，例如通过在组合物中包含未被除去大量的汁的全部紫色麝香葡萄葡萄的提取物，可以获得鞣花酸溶解度的进一步惊人的增加。 其他额外的花青素来源包括蓝莓，黑莓和覆盆子; 可以从水果加工废料流中获得额外的花青素来源，以提高生产过程的效率。