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公开(公告)号:US20120316240A1
公开(公告)日:2012-12-13
申请号:US13324750
申请日:2011-12-13
申请人: Shaochun Song , Yun Liu , Nan Jiang , Lei Yu
发明人: Shaochun Song , Yun Liu , Nan Jiang , Lei Yu
IPC分类号: C40B30/04 , A61P1/16 , C12Q1/02 , C12Q1/68 , A61K31/203
CPC分类号: C12Q1/6883 , C12Q2600/136 , C12Q2600/158 , G01N33/5067 , G01N2800/7052
摘要: Disclosed herein are methods that generally to the fields of pharmaceutical chemistry, biochemistry, molecular biology and medicine. More particularly, aspects of the invention concern methods to identify a predisposition for fibrosis in a biological sample, methods of identifying agents that modulate the onset of fibrosis, methods of making a formulation that inhibits the onset or progression of fibrosis, and methods of monitoring the progression of fibrosis or the efficacy of a fibrosis treatment.
摘要翻译: 本文公开了通常涉及药物化学,生物化学,分子生物学和医学领域的方法。 更具体地,本发明的方面涉及鉴定生物样品中纤维化倾向的方法,鉴定调节纤维化发作的试剂的方法,制备抑制纤维化发作或进展的制剂的方法以及监测 纤维化进展或纤维化治疗的功效。
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公开(公告)号:USD1048645S1
公开(公告)日:2024-10-22
申请号:US29894003
申请日:2023-06-05
申请人: Yun Liu
设计人: Yun Liu
摘要: FIG. 1 is a front, right and top perspective view of a safe box, showing my new design;
FIG. 2 is a rear, left and bottom perspective view thereof;
FIG. 3 is a front view thereof;
FIG. 4 is a rear view thereof;
FIG. 5 is a left side view thereof;
FIG. 6 is a right side view thereof;
FIG. 7 is a top plan view thereof; and,
FIG. 8 is a bottom plan view thereof.-
公开(公告)号:US08665731B1
公开(公告)日:2014-03-04
申请号:US13400320
申请日:2012-02-20
申请人: Anapathur V. Ramesh , Kishor S. Trivedi , Tilak C. Sharma , Dazhi Wang , David William Twigg , Le P. Nguyen , Yun Liu
发明人: Anapathur V. Ramesh , Kishor S. Trivedi , Tilak C. Sharma , Dazhi Wang , David William Twigg , Le P. Nguyen , Yun Liu
CPC分类号: H04L41/5009 , H04L41/12 , H04L41/145
摘要: A computer-based method for determining a probability that no path exists from a starting node to a target node within a network of nodes and directional links between pairs of nodes. The nodes and directional links form paths of a reliability graph and the method is performed using a computer coupled to a database. The method includes selecting a set of paths between the starting node and the target node that have been determined to be reliable, calculating a reliability of the union of the selected path sets, setting an upper bound for unreliability of the set of all paths, selecting a set of minimal cutsets from all cutsets that lie between the starting node and the target node, calculating the probability of the union of the minimal cutsets, and setting a lower bound for the unreliability of the set of all cutsets.
摘要翻译: 一种基于计算机的方法,用于确定节点网络中的起始节点和目标节点之间没有路径以及节点对之间的定向链路的概率。 节点和方向链路形成可靠性图的路径,并且使用耦合到数据库的计算机来执行该方法。 该方法包括:选择已经被确定为可靠的起始节点和目标节点之间的路径集合,计算所选路径集合的并集的可靠性,设置所有路径集合的不可靠性的上限,选择 来自位于起始节点和目标节点之间的所有切割线的一组最小切割,计算最小切割的并集的概率,以及为所有切割集的集合的不可靠性设置下限。
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公开(公告)号:US08617987B2
公开(公告)日:2013-12-31
申请号:US12982697
申请日:2010-12-30
申请人: Kah Wee Gan , Yonggang Jin , Yun Liu , Yaohuang Huang
发明人: Kah Wee Gan , Yonggang Jin , Yun Liu , Yaohuang Huang
CPC分类号: H01L25/105 , H01L21/486 , H01L21/568 , H01L23/49827 , H01L23/5389 , H01L24/19 , H01L24/96 , H01L2224/04105 , H01L2224/12105 , H01L2225/1035 , H01L2225/1058 , H01L2924/14 , H01L2924/15747 , H01L2924/181 , Y10T29/413 , Y10T29/49144 , Y10T29/49165 , H01L2924/00
摘要: An embedded wafer level ball grid array (eWLB) is formed by embedding a semiconductor die in a molding compound. A trench is formed in the molding compound with a laser drill. A first layer of copper is deposited on the sidewall of the trench by physical vapor deposition. A second layer of copper is then formed on the first layer of copper by an electroless process. A third layer of copper is then formed on the second layer by electroplating.
摘要翻译: 嵌入式晶片级球栅阵列(eWLB)通过将半导体管芯嵌入到模塑料中而形成。 在激光钻头的模塑料中形成沟槽。 第一层铜通过物理气相沉积沉积在沟槽的侧壁上。 然后通过无电解方法在第一层铜上形成第二层铜层。 然后通过电镀在第二层上形成第三层铜层。
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公开(公告)号:US20130071467A1
公开(公告)日:2013-03-21
申请号:US13492594
申请日:2012-06-08
申请人: Yoshiro Niitsu , Victor Knopov , Joseph E. Payne , Richard P. Witte , Mohammad Ahmadian , Loren A. Perelman , Violetta Akopian , Yasunobu Tanaka , Elena Feinstein , Sharon Avkin-Nahum , Hagar Kalinski , Igor Mett , Kenjiro Minomi , Wenbin Ying , Yun Liu
发明人: Yoshiro Niitsu , Victor Knopov , Joseph E. Payne , Richard P. Witte , Mohammad Ahmadian , Loren A. Perelman , Violetta Akopian , Yasunobu Tanaka , Elena Feinstein , Sharon Avkin-Nahum , Hagar Kalinski , Igor Mett , Kenjiro Minomi , Wenbin Ying , Yun Liu
IPC分类号: A61K9/127 , A61K31/713
CPC分类号: A61K9/1271 , A61K9/127 , A61K31/713 , C07H21/02 , C12N15/111 , C12N15/113 , C12N2310/11 , C12N2310/14 , C12N2320/32 , C12N2320/52
摘要: What is described are pharmaceutical compositions comprising a double-stranded nucleic acid molecule comprising a sense strand and an antisense strand wherein the sense and antisense strands are selected from the oligonucleotides described as SERPINH1_2 (SEQ ID NOS: 60 and 127), SERPINH1_45a (SEQ ID NOS: 98 and 165), and SERPINH1_51 (SEQ ID NOS: 101 and 168), and drug carrier comprising a mixture of a retinoid and a lipid vesicle, and methods of using these pharmaceutical compositions to treat a disease associated with hsp47 expression, including fibrosis.
摘要翻译: 描述的是包含包含有义链和反义链的双链核酸分子的药物组合物,其中有义链和反义链选自描述为SERPINH1_2的寡核苷酸(SEQ ID NO:60和127),SERPINH1_45a(SEQ ID NO: NOS:98和165)和SERPINH1_51(SEQ ID NO:101和168)和包含类视黄醇和脂质囊泡的混合物的药物载体,以及使用这些药物组合物治疗与hsp47表达相关的疾病的方法,包括 纤维化。
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公开(公告)号:US08340151B2
公开(公告)日:2012-12-25
申请号:US12966423
申请日:2010-12-13
申请人: Bo Liu , Yun Liu , Yehuda Y. Braiman
发明人: Bo Liu , Yun Liu , Yehuda Y. Braiman
IPC分类号: H01S3/08
CPC分类号: G02B27/14
摘要: A system and method for addition of broad-area semiconductor laser diode arrays are described. The system can include an array of laser diodes, a V-shaped external cavity, and grating systems to provide feedback for phase-locking of the laser diode array. A V-shaped mirror used to couple the laser diode emissions along two optical paths can be a V-shaped prism mirror, a V-shaped stepped mirror or include multiple V-shaped micro-mirrors. The V-shaped external cavity can be a ring cavity. The system can include an external injection laser to further improve coherence and phase-locking.
摘要翻译: 描述了用于添加广域半导体激光二极管阵列的系统和方法。 该系统可以包括激光二极管阵列,V形外腔和光栅系统,为激光二极管阵列的相位锁定提供反馈。 用于将激光二极管发射沿着两个光学路径耦合的V形镜可以是V形棱镜,V形阶梯镜或者包括多个V形微镜。 V形外腔可以是环形腔。 该系统可以包括外部注入激光器,以进一步提高相干性和相位锁定。
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公开(公告)号:US20120323164A1
公开(公告)日:2012-12-20
申请号:US13523940
申请日:2012-06-15
申请人: Malcolm E. Kenney , Yun Liu
发明人: Malcolm E. Kenney , Yun Liu
CPC分类号: A61K31/695 , A61K31/555 , A61K41/0071 , C09B47/0675 , C09B47/073 , C09B69/008
摘要: The use of phthalocyanines together with a free radical source for photodynamic therapy is described. The free radical sources cause the photodecomposition of the phthalocyanines, which can be useful for various reasons such as allowing light to penetrate to lower tissue levels that would otherwise be obscured. The nature of the phthalocyanine and the free radical source chosen can both have an influence on the rate of photodecomposition. The free radical sources can be provided along with the phthalocyanines either in free unattached form, or they can be attached to the phthalocyanines themselves.
摘要翻译: 描述了将酞菁与自由基源一起用于光动力疗法。 自由基源导致酞菁的光分解,其可以由于各种原因而有用,例如允许光穿透以降低否则将被模糊的组织水平。 选择的酞菁和自由基的性质都可以对光分解速率产生影响。 自由基源可以与酞菁一起以游离的未附着形式提供,或者它们可以连接到酞菁本身。
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公开(公告)号:US20120201687A1
公开(公告)日:2012-08-09
申请号:US13496887
申请日:2010-06-24
申请人: Hanjun Song , Yun Liu , Nicolas Blitterswyk
发明人: Hanjun Song , Yun Liu , Nicolas Blitterswyk
IPC分类号: F03D3/06
CPC分类号: F03D3/061 , F05B2240/214 , F05B2250/25 , Y02E10/74
摘要: A vertical axis wind turbine comprising blade(s) characterized in an airfoil cross section, wherein the top end and the bottom end of said blade(s) are rotationally off-set from each other, twisted up with a vertical line vertical to the horizontal plane.
摘要翻译: 一种垂直轴风力涡轮机,其包括以翼型横截面为特征的叶片,其中所述叶片的顶端和底端彼此旋转偏离,与垂直于水平线的垂直线扭绞 飞机
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公开(公告)号:US20120168943A1
公开(公告)日:2012-07-05
申请号:US12982719
申请日:2010-12-30
申请人: Kah Wee Gan , Yonggang Jin , Anandan Ramasamy , Yun Liu
发明人: Kah Wee Gan , Yonggang Jin , Anandan Ramasamy , Yun Liu
IPC分类号: H01L23/485 , H01L21/50
CPC分类号: H01L24/96 , H01L21/561 , H01L21/568 , H01L2224/0401 , H01L2224/04105 , H01L2224/08235 , H01L2224/12105 , H01L2924/01006 , H01L2924/01029 , H01L2924/01033 , H01L2924/01079 , H01L2924/014
摘要: A semiconductor package and method of forming the same is described. The semiconductor package is formed from a semiconductor die cut from a semiconductor wafer that has a passivation layer. The semiconductor wafer is exposed to ionized gas causing the passivation layer to roughen. The semiconductor wafer is cut to form a plurality of semiconductor dies each with a roughened passivation layer. The plurality of semiconductor dies are placed on an adhesive layer to form a reconstituted wafer, and an encapsulation layer is formed enclosing the adhesive layer and the plurality of semiconductor dies. The passivation layer is removed and the semiconductor package formed includes electrical contacts for establishing electrical connections external to the semiconductor package.
摘要翻译: 描述了半导体封装及其形成方法。 半导体封装由从具有钝化层的半导体晶片切割的半导体管芯形成。 将半导体晶片暴露于电离气体,导致钝化层变粗糙。 切割半导体晶片以形成多个具有粗糙化钝化层的半导体管芯。 多个半导体管芯被放置在粘合剂层上以形成重构的晶片,并且形成包封粘合剂层和多个半导体管芯的封装层。 去除钝化层,形成的半导体封装包括用于在半导体封装外部建立电连接的电触头。
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公开(公告)号:US20120099997A1
公开(公告)日:2012-04-26
申请号:US13380793
申请日:2010-06-24
申请人: Hanjun Song , Yun Liu , Nicolas Blitterswyk
发明人: Hanjun Song , Yun Liu , Nicolas Blitterswyk
IPC分类号: F03D3/06
CPC分类号: F03D3/064 , F03D3/065 , F05B2240/214 , F05B2250/25 , Y02E10/74
摘要: A vertical axis wind turbine comprising a main wind blade with one or more blade(s), at least one connecting arm, attached to main blade and an abutment of connecting arm arranged with axle hole of wind rotor shaft, wherein, a main blade is fixed with abutment of connecting arm through connecting arm to form an vertical axis wind turbine.
摘要翻译: 一种垂直轴风力涡轮机,包括具有一个或多个叶片的主风叶片,连接到主叶片的至少一个连接臂和布置有风力转子轴的轴孔的连接臂的邻接,其中主叶片是 通过连接臂固定连接臂的邻接,形成垂直轴风力发电机。
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