利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

7 条记录 (耗时 0.023 秒)

    Method for quantifying specific compound
    2.
    发明授权
    Method for quantifying specific compound 失效
    定量化合物的方法

    公开(公告)号：US5565085A

    公开(公告)日：1996-10-15

    申请号：US428040

    申请日：1995-04-25

    申请人： Shin Ikeda ,  Toshihiko Yoshioka ,  Shiro Nankai ,  Haruhiro Tsutsumi ,  Hideyuki Baba ,  Yoshinobu Tokuno

    发明人： Shin Ikeda ,  Toshihiko Yoshioka ,  Shiro Nankai ,  Haruhiro Tsutsumi ,  Hideyuki Baba ,  Yoshinobu Tokuno

    IPC分类号： G01N27/416 ,  C12Q1/00 ,  G01N27/30 ,  G01N27/327 ,  G01N27/26

    CPC分类号： C12Q1/001 ,  Y10S435/817

    摘要： A biosensor for quantifying a specific compound has a reaction layer containing at least an enzyme, and an electrode system having a working electrode and a counter electrode formed on an insulating base plate; the biosensor detects the specific compound contained in a sample on the basis of an electrochemical response. In quantifying, the working electrode and the counter electrode are short-circuited before the voltage is applied therebetween. The short-circuiting eliminates measuring errors that may occur due to nonuniform dissolution of the reaction layer in a sample, and achieves highly reliable quantification of a specific compound.

    摘要翻译： 用于定量特定化合物的生物传感器具有至少含有酶的反应层和在绝缘基板上形成有工作电极和对电极的电极系统; 生物传感器基于电化学响应来检测样品中包含的特定化合物。 在量化之前，工作电极和对电极在施加电压之前短路。 短路消除了由于反应层在样品中的不均匀溶解而可能发生的测量误差，并且实现了特定化合物的高度可靠的定量。

    Biosensor
    4.
    发明授权
    Biosensor 失效
    生物传感器

    公开(公告)号：US5512159A

    公开(公告)日：1996-04-30

    申请号：US293131

    申请日：1994-08-19

    申请人： Toshihiko Yoshioka ,  Mariko Kawaguri ,  Shiro Nankai ,  Haruhiro Tsutsumi ,  Hideyuki Baba ,  Yoshinobu Tokuno ,  Shoji Miyazaki

    发明人： Toshihiko Yoshioka ,  Mariko Kawaguri ,  Shiro Nankai ,  Haruhiro Tsutsumi ,  Hideyuki Baba ,  Yoshinobu Tokuno ,  Shoji Miyazaki

    IPC分类号： G01N27/28 ,  C12M1/34 ,  C12M1/40 ,  C12Q1/00 ,  C12Q1/54 ,  G01N27/327 ,  G01N33/483

    CPC分类号： C12Q1/001

    摘要： A biosensor of the present invention is provided with an insulating base plate, an electrode system mainly consisting of a working electrode and a counter electrode formed on the insulating base plate, and a reaction layer on the electrode system. The counter electrode is partially a circular arc. A manufacturing method of the biosensor of the present invention is comprised of a step to form a base by arranging leads, an electrode system, and an insulating layer on an insulating base plate, and a step to form a reaction layer mainly composed of an enzyme on the electrode system. Since the counter electrode is partially in the shape of a circular arc, the reaction layer is easily formed and prevented from delaminating, whereby the measuring accuracy, preservative properties and reliability of the biosensor are improved. The present invention enables highly efficient biosensors to be mass produced at low cost.

    摘要翻译： 本发明的生物传感器设置有绝缘基板，主要由在绝缘基板上形成的工作电极和对电极组成的电极系统和电极系统上的反应层。 对电极部分是圆弧。 本发明的生物传感器的制造方法包括通过在绝缘基板上排列引线，电极系统和绝缘层形成基底的步骤，以及形成主要由酶组成的反应层的步骤 在电极系统上。 由于对电极部分为圆弧形状，反应层易于形成并防止分层，从而提高了生物传感器的测量精度，防腐性能和可靠性。 本发明能够以低成本批量生产高效生物传感器。

    Biosensor and measuring apparatus using the same
    5.
    发明授权
    Biosensor and measuring apparatus using the same 失效
    生物传感器和使用其的测量装置

    公开(公告)号：US5320732A

    公开(公告)日：1994-06-14

    申请号：US75859

    申请日：1993-06-11

    申请人： Shiro Nankai ,  Mariko Kawaguri ,  Toshihiko Yoshioka ,  Haruhiro Tsutsumi ,  Minoru Fukuda

    发明人： Shiro Nankai ,  Mariko Kawaguri ,  Toshihiko Yoshioka ,  Haruhiro Tsutsumi ,  Minoru Fukuda

    IPC分类号： G01N27/28 ,  G01N33/487 ,  G01N27/26

    CPC分类号： G01N27/3272

    摘要： The subject invention provides a simple sensor and an easy to handle biosensor measuring apparatus for the purpose of making measurements easily, rapidly and with high accuracy for specific components within a biological specimen such as blood.The biosensor of the subject invention is provided with a protrusion or a depression in a portion of a base having at least a measurement electrode and an opposing electrode. Also, the biosensor measuring apparatus is so configurated to have a mating means in the main body of the measuring apparatus freely supporting this biosensor to contact the said sensor's protrusion or depression, and further having the activating switch of the driving power supply located in this mating means.By means of these, it is possible to prevent wasteful measuring operations, as noted in the prior art biosensors, such as inserting the sensor backwards and making measurements with the sensor inserted backwards.

    摘要翻译： 本发明提供了一种简单的传感器和易于处理的生物传感器测量装置，用于容易，快速且高度精确地测量诸如血液的生物样本内的特定组分的目的。 本发明的生物传感器在至少具有测量电极和相对电极的基部的一部分中设置有突起或凹陷。 此外，生物传感器测量装置被配置为具有在测量装置的主体中具有自由支撑该生物传感器的配合装置以接触所述传感器的突起或凹陷，并且还具有位于该配合中的驱动电源的启动开关 手段。 通过这些，可以防止浪费的测量操作，如现有技术的生物传感器中所述，例如向后插入传感器并且使传感器向后插入进行测量。

    Biosensor
    7.
    发明授权
    Biosensor 有权
    生物传感器

    公开(公告)号：US06830669B2

    公开(公告)日：2004-12-14

    申请号：US09890761

    申请日：2001-10-16

    申请人： Shoji Miyazaki ,  Haruhiro Tsutsumi ,  Eriko Yamanishi

    发明人： Shoji Miyazaki ,  Haruhiro Tsutsumi ,  Eriko Yamanishi

    IPC分类号： G01N2726

    CPC分类号： C12Q1/001 ,  G01N27/3272

    摘要： A biosensor having an electrode layer, which includes a working electrode and a counter electrode, and a reagent layer 10 are formed on an insulating support. Further, a spacer having a long and narrow cut-out portion on the reagent layer is bonded to a cover having an air hole to form a cavity that sucks blood as a liquid sample by capillary phenomenon, and a portion of side walls of the spacer and the cover, which side walls face the cavity, is subjected to a treatment for making the portion itself have hydrophilicity. Accordingly, when blood is sucked into the cavity by capillary phenomenon, the suction is promoted, and the performance of a sensor of the biosensor is improved. Further, the process of manufacturing the sensor is simplified, thereby resulting in increased productivity.

    摘要翻译： 具有工作电极和对电极的电极层的生物传感器和试剂层10形成在绝缘支撑体上。 此外，在试剂层上具有长而窄的切出部分的间隔物结合到具有空气孔的盖上，以形成通过毛细管现象吸取血液作为液体样品的空腔，并且间隔物的侧壁的一部分 并且将侧壁面向空腔的盖子进行处理以使该部分本身具有亲水性。 因此，当通过毛细管现象将血液吸入空腔时，促进吸力，提高生物传感器的传感器的性能。 此外，简化了传感器的制造过程，从而提高了生产率。