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1.发明申请METHOD FOR METHANOL INDEPENDENT INDUCTION FROM METHANOL INDUCIBLE PROMOTERS IN PICHIA 失效甲基葡萄糖独立诱导甲基淀粉诱导剂在PICHIA中的应用公开(公告)号：US20120142053A1
公开(公告)日：2012-06-07
申请号：US13396925
申请日：2012-02-15
申请人： Noriko Tsutsumi , Yuji Terui , Shinobu Takagi , XiangYu Kong
发明人： Noriko Tsutsumi , Yuji Terui , Shinobu Takagi , XiangYu Kong
CPC分类号： C12P21/02 , C07K14/39 , C12N15/815
摘要： A method for producing a polypeptide in a methylotrophic yeast host cell is described, where expression of the polypeptide is controlled by a methanol inducible promoter, including: i) expression of a positive regulator from a non-native promoter, the positive regulator activating transcription from the methanol inducible promoter, and ii) no addition of methanol.
摘要翻译： 描述了在甲基营养酵母宿主细胞中产生多肽的方法，其中多肽的表达由甲醇诱导型启动子控制，其包括：i）从非天然启动子表达阳性调节剂，阳性调节剂从 甲醇诱导型启动子，和ii）不加甲醇。
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2.发明授权Method for methanol independent induction from methanol inducible promoters in Pichia 失效甲醇独立诱导甲基诱导启动子在毕赤酵母中的方法公开(公告)号：US08143023B2
公开(公告)日：2012-03-27
申请号：US12521856
申请日：2008-01-25
申请人： Shinobu Takagi , Noriko Tsutsumi , Yuji Terui , XiangYu Kong
发明人： Shinobu Takagi , Noriko Tsutsumi , Yuji Terui , XiangYu Kong
IPC分类号： C12P21/06
CPC分类号： C12P21/02 , C07K14/39 , C12N15/815
摘要： A method for producing a polypeptide in a methylotrophic yeast host cell is described, where expression of the polypeptide is controlled by a methanol inducible promoter, including: i) expression of a positive regulator from a non-native promoter, the positive regulator activating transcription from the methanol inducible promoter, and ii) no addition of methanol.
摘要翻译： 描述了在甲基营养酵母宿主细胞中产生多肽的方法，其中多肽的表达由甲醇诱导型启动子控制，其包括：i）从非天然启动子表达阳性调节剂，阳性调节剂从 甲醇诱导型启动子，和ii）不加甲醇。
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公开(公告)号：US08236528B2
公开(公告)日：2012-08-07
申请号：US13396925
申请日：2012-02-15
申请人： Shinobu Takagi , Noriko Tsutsumi , Yuji Terui , XiangYu Kong
发明人： Shinobu Takagi , Noriko Tsutsumi , Yuji Terui , XiangYu Kong
IPC分类号： C12P21/06
CPC分类号： C12P21/02 , C07K14/39 , C12N15/815
摘要： A method for producing a polypeptide in a methylotrophic yeast host cell is described, where expression of the polypeptide is controlled by a methanol inducible promoter, including: i) expression of a positive regulator from a non-native promoter, the positive regulator activating transcription from the methanol inducible promoter, and ii) no addition of methanol.
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4.发明申请Method for methanol independent induction from methanol inducible promoters in Pichia 失效甲醇独立诱导甲基诱导启动子在毕赤酵母中的方法公开(公告)号：US20090311749A1
公开(公告)日：2009-12-17
申请号：US12521856
申请日：2008-01-25
申请人： Shinobu Takagi , Noriko Tsutsumi , Yuji Terui , XiangYu Kong
发明人： Shinobu Takagi , Noriko Tsutsumi , Yuji Terui , XiangYu Kong
IPC分类号： C12P21/00
CPC分类号： C12P21/02 , C07K14/39 , C12N15/815
摘要： The present invention relates to a method for producing a polypeptide in a methylotrophic yeast host cell, wherein expression of the polypeptide is controlled by a methanol inducible promoter, comprising: i) expression of a positive regulator from a non-native promoter, said positive regulator activating transcription from the methanol inducible promoter, and ii) no addition of methanol.
摘要翻译： 本发明涉及在甲基营养酵母宿主细胞中产生多肽的方法，其中多肽的表达由甲醇诱导型启动子控制，其包括：i）从非天然启动子，所述阳性调节子 激活甲醇诱导型启动子的转录，以及ii）不添加甲醇。
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公开(公告)号：USD581067S1
公开(公告)日：2008-11-18
申请号：US29300087
申请日：2008-02-20
申请人： Yuji Terui
设计人： Yuji Terui
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