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公开(公告)号:US4731265A
公开(公告)日:1988-03-15
申请号:US896964
申请日:1986-08-15
申请人: Shozo Hirao , Ayumu Yasuda , Yoshihiro Ohta , Takashi Nakai , Kazuo Seto
发明人: Shozo Hirao , Ayumu Yasuda , Yoshihiro Ohta , Takashi Nakai , Kazuo Seto
CPC分类号: B27K3/22 , B27K3/26 , B27K2240/30 , B27K3/04 , Y10S428/907 , Y10S428/921 , Y10T428/662
摘要: A method of manufacturing a modified wood material, wherein a raw wood material is processed in a first bath of a first solution containing metallic ions high in the affinity and showing insoluble and non-flammable properties within the wood material, and then in a second bath of a second solution containing negative ions which produces an insoluble, non-flammable inorganic composition upon reaction with the metallic ions, whereby the obtained modified wood material is made to have the insoluble, non-flammable inorganic composition produced and fixed therein to allow the material to hold a good flame retardancy and excellent rotproof and mothproof properties.
摘要翻译: 一种制造改性木材的方法,其中将原木材料在含有金属离子的第一溶液的第一浴中进行处理,所述第一溶液含有高亲和性的金属离子,并在木材内表现出不溶性和不可燃性,然后在第二浴中 的含有负离子的第二溶液,其在与金属离子反应时产生不溶的不可燃无机组合物,由此所得改性木材材料制成具有生产和固定在其中的不溶性不可燃无机组合物,以允许材料 具有良好的阻燃性和优异的防腐性和防蛀性。
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公开(公告)号:US4857365A
公开(公告)日:1989-08-15
申请号:US157228
申请日:1988-02-18
申请人: Shozo Hirao , Hiroaki Usui , Yoshihiro Ohta , Takashi Nakai , Hiroyuki Ishikawa , Satoru Konishi
发明人: Shozo Hirao , Hiroaki Usui , Yoshihiro Ohta , Takashi Nakai , Hiroyuki Ishikawa , Satoru Konishi
IPC分类号: B27K3/32
摘要: A method of manufacturing a modifed wood material can fix within a raw wood material an insoluble, non-flammable inorganic compound with a highly efficient reaction achieved between cations and anions by sequentially immersing the raw wood material at least three times alternately in each of, and different one from that employed immediately before of a first water-soluble inorganic substance solution containing cations and a second water-soluble inorganic substance solution containing anions.
摘要翻译: 制造修改后的木材的方法可以在原材料中固定不溶性的不可燃无机化合物,其中阳离子和阴离子之间实现的高效反应是通过将原木材料交替地在 与之前使用的第一种含有阳离子的水溶性无机物质溶液和含有阴离子的第二种水溶性无机物质溶液不同。
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公开(公告)号:US09061030B2
公开(公告)日:2015-06-23
申请号:US13883910
申请日:2011-11-02
申请人: Charles Kim , Takashi Nakai , Thomas Wai-Ho Lee , Joel Moore , Nicholas Robert Perl , Jason Rohde
发明人: Charles Kim , Takashi Nakai , Thomas Wai-Ho Lee , Joel Moore , Nicholas Robert Perl , Jason Rohde
IPC分类号: A61K31/506 , C07D401/04 , C07D401/14 , C07D403/04 , C07D413/14 , C07D417/04 , C07D417/14 , C07D405/14 , A61K31/427 , A61K31/4439 , A61K31/444
CPC分类号: A61K31/5377 , A61K31/427 , A61K31/4439 , A61K31/444 , A61K31/497 , A61K31/506 , A61K45/06 , C07D401/04 , C07D401/14 , C07D403/04 , C07D405/14 , C07D413/14 , C07D417/04 , C07D417/14
摘要: Compounds of Formula IA and Formula IB are described. They are useful as stimulators of sGC, particularly NO-independent, heme-dependent stimulators. These compounds may be useful for treating, preventing or managing various disorders that are herein disclosed.
摘要翻译: 描述了式IA和式IB的化合物。 它们作为sGC的刺激剂是有用的,特别是NO不依赖于血红素依赖性刺激物。 这些化合物可用于治疗,预防或治疗本文公开的各种疾病。
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公开(公告)号:US08922597B2
公开(公告)日:2014-12-30
申请号:US13415457
申请日:2012-03-08
申请人: Takashi Nakai , Goki Toshima , Ryutaro Oke , Junichi Maruyama
发明人: Takashi Nakai , Goki Toshima , Ryutaro Oke , Junichi Maruyama
IPC分类号: G09G3/36
CPC分类号: G09G3/3614 , G09G3/3648 , G09G3/3688 , G09G2320/0204 , G09G2320/0223 , G09G2320/0257
摘要: A liquid crystal display device includes a plurality of pixel circuits, data lines, and a data-line driving circuit connected to the data lines. Each of the pixel circuits includes a pixel capacitance having one end provided with a common potential. In accordance with a grayscale value for one of the plurality of pixel circuits, the data-line driving circuit selectively outputs a positive-polarity signal and a negative-polarity signal to the one pixel circuit. The data-line driving circuit outputs the positive-polarity signal and the negative-polarity signal so that an average of a potential of the positive-polarity signal and a potential of the negative-polarity signal corresponding to the grayscale value changes in accordance with the grayscale value, a temperature, and a position of the one pixel circuit.
摘要翻译: 液晶显示装置包括连接到数据线的多个像素电路,数据线和数据线驱动电路。 每个像素电路包括一端具有公共电位的像素电容。 根据多个像素电路中的一个像素电路的灰度值,数据线驱动电路选择性地向一个像素电路输出正极性信号和负极性信号。 数据线驱动电路输出正极性信号和负极性信号,使得正极性信号的电位的平均值和对应于灰度值的负极性信号的电位根据 灰度值,温度和一个像素电路的位置。
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公开(公告)号:US08795586B2
公开(公告)日:2014-08-05
申请号:US11720585
申请日:2005-11-14
申请人: Kinya Kawase , Takashi Nakai
发明人: Kinya Kawase , Takashi Nakai
IPC分类号: B22F1/00
CPC分类号: B22F3/02 , B22F2998/10 , B22F2999/00 , B22F1/0059 , B22F3/10 , B22F2203/11
摘要: A sinter of stable quality is produced by molding a powder for powder metallurgy. This process includes successively conducting the following steps: charging a powder and a solid lubricant into a mold compact formation in which the powder charged into the mold is compacted; releasing the compact from the mold; and the powder for powder metallurgy is charged again into the mold after the release step. The temperature of the mold is set at a value in the range of from the boiling point of water to the melting point of the solid lubricant. The compact can be continuously formed without causing, e.g., a failure in the feeding of the powder for powder metallurgy. The sinter obtained by sintering the compact is almost even in strength and density.
摘要翻译: 通过成型用于粉末冶金的粉末来制造质量稳定的烧结体。 该方法包括依次进行以下步骤:将粉末和固体润滑剂装入模压成型体中,在其中将装入模具中的粉末压实; 从模具中释放压块; 粉末冶金粉末在脱模步骤后再次装入模具中。 模具的温度设定在从水的沸点到固体润滑剂的熔点的范围内的值。 可以连续地形成压块,而不会导致例如用于粉末冶金的粉末的供给失败。 通过烧结所得到的烧结体的强度和密度几乎均匀。
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公开(公告)号:US08748442B2
公开(公告)日:2014-06-10
申请号:US13174676
申请日:2011-06-30
申请人: Charles Kim , Takashi Nakai , Thomas Wai-Ho Lee , Joel Moore , Nicholas Robert Perl , Jason Rohde , Rajesh R Iyengar , Ara Mermerian , Angelika Fretzen
发明人: Charles Kim , Takashi Nakai , Thomas Wai-Ho Lee , Joel Moore , Nicholas Robert Perl , Jason Rohde , Rajesh R Iyengar , Ara Mermerian , Angelika Fretzen
IPC分类号: A01N43/54 , A61K31/505 , A01N43/40 , A61K31/44 , C07D401/00 , C07D403/00 , C07D405/00 , C07D409/00 , C07D411/00 , C07D413/00 , C07D417/00 , C07D419/00
CPC分类号: C07D401/04 , A61K31/4155 , A61K31/4439 , A61K31/444 , A61K31/497 , A61K31/506 , A61K31/522 , A61K31/5365 , A61K45/06 , C07D401/14 , C07D403/04 , C07D403/14 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , C07D473/34 , C07D491/048 , C07D498/04 , A61K2300/00
摘要: Compounds of Formula I are described. They are useful as stimulators of sGC, particularly NO-independent, heme-dependent stimulators. These compounds may be useful for treating, preventing or managing various disorders that are herein disclosed.
摘要翻译: 描述式I化合物。 它们作为sGC的刺激剂是有用的,特别是NO不依赖于血红素依赖性刺激物。 这些化合物可用于治疗,预防或治疗本文公开的各种疾病。
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公开(公告)号:US20140088071A1
公开(公告)日:2014-03-27
申请号:US13883910
申请日:2011-11-02
申请人: Takashi Nakai , Thomas Wai-Ho Lee , Charles Kim , Joel Moore , Nicholas Robert Perl , Jason Rohde
发明人: Takashi Nakai , Thomas Wai-Ho Lee , Charles Kim , Joel Moore , Nicholas Robert Perl , Jason Rohde
IPC分类号: A61K31/506 , A61K31/4439 , C07D401/14 , A61K31/427 , C07D401/04 , C07D417/14 , C07D405/14 , C07D403/04 , C07D413/14 , A61K31/444
CPC分类号: A61K31/5377 , A61K31/427 , A61K31/4439 , A61K31/444 , A61K31/497 , A61K31/506 , A61K45/06 , C07D401/04 , C07D401/14 , C07D403/04 , C07D405/14 , C07D413/14 , C07D417/04 , C07D417/14
摘要: Compounds of Formula (IA) and Formula (IB) are described. They are useful as stimulators of sGC, particularly NO-independent, heme-dependent stimulators. These compounds may be useful for treating, preventing or managing various disorders that are herein disclosed.
摘要翻译: 描述了式(IA)和式(IB)的化合物。 它们作为sGC的刺激剂是有用的,特别是NO不依赖于血红素依赖性刺激物。 这些化合物可用于治疗,预防或治疗本文公开的各种疾病。
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公开(公告)号:US20130178453A1
公开(公告)日:2013-07-11
申请号:US13578009
申请日:2011-02-09
申请人: Jason Rohde , Bo Peng , Takashi Nakai , Kevin Sprott , Ara Mermerían , Wayne C. Schairer , Galen John Carey
发明人: Jason Rohde , Bo Peng , Takashi Nakai , Kevin Sprott , Ara Mermerían , Wayne C. Schairer , Galen John Carey
IPC分类号: C07D495/04 , C07D491/048 , A61K31/5377 , A61K31/437 , A61K31/4709 , A61K31/429 , C07D513/04 , A61K45/06 , A61K31/407 , A61K31/404 , A61K31/424
CPC分类号: C07D495/04 , A61K31/404 , A61K31/407 , A61K31/424 , A61K31/429 , A61K31/437 , A61K31/4709 , A61K31/5377 , A61K45/06 , C07D491/048 , C07D513/04 , C07D519/00
摘要: The present disclosure relates to compounds useful as agonists of the cannabinoid receptors. The disclosure also provides pharmaceutically acceptable compositions comprising the compounds of the disclosure and methods of using the compositions in the treatment of various disorders, either alone or in combination therapy. The compounds of the invention have Formula (I).
摘要翻译: 本公开涉及可用作大麻素受体的激动剂的化合物。 本公开还提供药学上可接受的组合物,其包含本公开的化合物和使用组合物单独或联合治疗中各种疾病的治疗方法。 本发明的化合物具有式(I)。
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公开(公告)号:US20130011866A1
公开(公告)日:2013-01-10
申请号:US13595139
申请日:2012-08-27
申请人: Tomoyuki Igawa , Shinya Ishii , Atsuhiko Maeda , Takashi Nakai
发明人: Tomoyuki Igawa , Shinya Ishii , Atsuhiko Maeda , Takashi Nakai
IPC分类号: G01N33/53
CPC分类号: C12N15/1037 , A61K39/12 , A61K39/145 , A61K2039/505 , A61K2039/544 , A61K2039/545 , A61K2039/552 , C07K16/244 , C07K16/248 , C07K16/2866 , C07K2317/24 , C07K2317/56 , C07K2317/565 , C07K2317/622 , C07K2317/76 , C07K2317/77 , C07K2317/92 , C12N2760/16111 , C12N2760/16134 , C12N2770/20071 , G01N33/6854 , G01N2500/00
摘要: The present inventors discovered that antibodies having weaker antigen-binding activity at the early endosomal pH in comparison with that at the pH of plasma are capable of binding to multiple antigen molecules with a single antibody molecule, have long half-lives in plasma, and have improved durations of time in which they can bind to antigen.
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公开(公告)号:US08153053B2
公开(公告)日:2012-04-10
申请号:US12645198
申请日:2009-12-22
申请人: Takashi Nakai , Kinya Kawase
发明人: Takashi Nakai , Kinya Kawase
IPC分类号: B22F3/12
CPC分类号: B22F3/02 , B22F2003/026 , B22F2003/145 , B30B15/0011
摘要: A method for forming a compact from a powder wherein a forming portion 1A in a mold body 2 is filled with a raw powder and upper and lower punches 3,4 are fitted into the forming portion 1A to form the compact. Prior to filling the forming portion 1A with the raw powder M, a solution L with a lubricant being uniformly dissolved in a solvent is applied to a peripheral portion of the forming portion 1A, and then the solution is evaporated, thus forming a crystallized layer B thereon. Thus, the reduction of a force for ejecting the compact is realized, while improving the density of the compact, realizing the stable and successive production of the compact.
摘要翻译: 一种从粉末形成压块的方法,其中模具体2中的成形部分1A填充有原料粉末,上冲头3,4和下冲头3,4装配到成形部分1A中以形成压块。 在用原料粉末M填充成形部1A之前,将具有均匀溶解在溶剂中的润滑剂的溶液L施加到成形部1A的周边部分,然后蒸发溶液,从而形成结晶化层B 上。 因此,在提高压实体的密度的同时,实现了用于压出压块的力的减小,实现了压块的稳定且连续的生产。
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