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    TRANSURETHRAL ULTRASOUND PROBE FOR TREATMENT OF PROSTATE
    2.
    发明申请
    TRANSURETHRAL ULTRASOUND PROBE FOR TREATMENT OF PROSTATE 审中-公开
    用于治疗前列腺的超声超声探头

    公开(公告)号：US20110301508A1

    公开(公告)日：2011-12-08

    申请号：US13202602

    申请日：2010-02-05

    申请人： Shriram Sethuraman ,  Gosta Ehnholm ,  Balasundara I. Raju

    发明人： Shriram Sethuraman ,  Gosta Ehnholm ,  Balasundara I. Raju

    IPC分类号： A61N7/00

    CPC分类号： A61N7/022 ,  A61B2017/00911 ,  A61B2018/00023 ,  A61B2090/0472 ,  A61B2090/374

    摘要： A probe (40) includes a shaft (52) on which an ultrasound element (42) is mounted. An outer sheath (64) and an acoustic membrane (66) surround the shaft and the ultrasound element such that the shaft and ultrasound element are rotatable therein. Passages (56) supply a cooling and acoustic coupling fluid to an inlet and outlet (48) adjacent the acoustic element to cool the acoustic element and fill a volume between the acoustic element and the acoustic sheath with the fluid. A balloon (90) mounted on the probe is selectively inflated in order to fix a position of the probe. A drain (94, 98) drains urine and other bodily fluids through the probe.

    摘要翻译： 探针（40）包括其上安装有超声波元件（42）的轴（52）。 围绕轴和超声波元件的外护套（64）和声膜（66）使得轴和超声元件能够在其中旋转。 通道（56）将冷却和声耦合流体提供给邻近声学元件的入口和出口（48），以冷却声学元件并用流体填充声学元件和声学护套之间的体积。 安装在探针上的球囊（90）选择性地膨胀以固定探针的位置。 排水口（94,98）通过探头排出尿液和其他体液。

    REAL-TIME MONITORING AND CONTROL OF HIFU THERAPY IN MULTIPLE DIMENSIONS
    3.
    发明申请
    REAL-TIME MONITORING AND CONTROL OF HIFU THERAPY IN MULTIPLE DIMENSIONS 审中-公开
    多维度HIFU治疗的实时监测与控制

    公开(公告)号：US20130096597A1

    公开(公告)日：2013-04-18

    申请号：US13805396

    申请日：2011-04-27

    申请人： Ajay Anand ,  John Petruzzello ,  Shiwei Zhou ,  Shriram Sethuraman

    发明人： Ajay Anand ,  John Petruzzello ,  Shiwei Zhou ,  Shriram Sethuraman

    IPC分类号： A61N7/00

    摘要： Energy is transferred (336) to cause a mechanical property of biological tissue to change, as in ablation. An effect of the transferring is examined in more than one spatial dimension to, for example, make an ablation halting decision for a treatment region, i.e., line (312) or layer (314), or for a location (316) within the region. Halting decisions can be based on lesion-central and/or lesion-peripheral longitudinal displacement of treated tissue evaluated in real time against a characteristic curve. Steering in the azimuthal and/or elevation direction is afforded by, for example, linear, or 2D, multi-channel ultrasound arrays for therapy and imaging. Protocols includable are region-wide scanning (SI 010) and location-by-location completion for both (HIFU) therapy and tracking (acoustic-radiation-forced-based) displacement of treated tissue. Fine, location- to-location monitoring can be used for relatively inhomogeneous tissue; whereas, quicker, sparser and more generalized monitoring (1 100, 1200) can be employed for relatively homogeneous tissue.

    摘要翻译： 转移能量（336）以使生物组织的机械性能发生变化，如消融。 在多于一个的空间维度中检查转移的效果，以便例如对处理区域（即，线（312）或层（314））或区域（316）内的消融停止决定 。 暂停决定可以基于对特征曲线实时评估的处理组织的病变中心和/或病变周边纵向位移。 方位角和/或高度方向的转向由例如用于治疗和成像的线性或2D多通道超声阵列提供。 可包括的协议是针对处理组织（HIFU）治疗和跟踪（基于声辐射的强制）位移的区域扫描（SI 010）和逐位置完成。 精细的位置到位置监测可用于相对不均匀的组织; 而对于相对均匀的组织，可以采用更快，更稀疏和更广泛的监测（110 100）。

    DISPLACEMENT FEEDBACK DEVICE AND METHOD FOR SENSING OR THERAPY DELIVERY PROBES
    5.
    发明申请
    DISPLACEMENT FEEDBACK DEVICE AND METHOD FOR SENSING OR THERAPY DELIVERY PROBES 审中-公开
    位移反馈装置和用于感测或治疗传送探针的方法

    公开(公告)号：US20140171792A1

    公开(公告)日：2014-06-19

    申请号：US14236112

    申请日：2012-07-30

    申请人： Sandeep M. Dalal ,  Cynthia Ming-Fu Kung ,  Shriram Sethuraman ,  Jochen Kruecker

    发明人： Sandeep M. Dalal ,  Cynthia Ming-Fu Kung ,  Shriram Sethuraman ,  Jochen Kruecker

    IPC分类号： A61B5/06

    CPC分类号： A61B5/065 ,  A61B17/3403 ,  A61B2090/061 ,  A61B2090/062 ,  F04C2270/041

    摘要： A device, system and method for accessing internal tissue include a probe (108) disposed on a distal end portion of a medical device and configured to be inserted into a body along a trajectory path. A sensor (102) is mounted on a displacement tracker portion (104) of the medical device which is disposed on a proximal end portion of the device. The sensor is configured to measure a distance parallel to the probe between the displacement tracker portion and a tissue surface such that a position of the probe is determinable relative to the tissue surface upon advance or retraction of the probe along the trajectory path.

    摘要翻译： 用于访问内部组织的装置，系统和方法包括设置在医疗装置的远端部分上并且被配置为沿着轨迹路径插入到身体中的探针（108）。 传感器（102）安装在设置在装置的近端部分上的医疗装置的移动跟踪器部分（104）上。 传感器被配置成测量平行于位移跟踪器部分和组织表面之间的探头的距离，使得当探针沿着轨迹路径前进或缩回时探针的位置相对于组织表面是可确定的。

    INTRAVASCULAR PHOTOACOUSTIC AND UTRASOUND ECHO IMAGING
    6.
    发明申请
    INTRAVASCULAR PHOTOACOUSTIC AND UTRASOUND ECHO IMAGING 审中-公开
    血管内照射和非对称ECHO成像

    公开(公告)号：US20110021924A1

    公开(公告)日：2011-01-27

    申请号：US12449384

    申请日：2008-02-01

    申请人： Shriram Sethuraman ,  Stanislav Y. Emelianov ,  Richard W. Smalling ,  Salavat R. Aglyamov

    发明人： Shriram Sethuraman ,  Stanislav Y. Emelianov ,  Richard W. Smalling ,  Salavat R. Aglyamov

    IPC分类号： A61B8/14 ,  A61B6/00

    CPC分类号： A61B8/5261 ,  A61B5/0075 ,  A61B5/0095 ,  A61B5/02007 ,  A61B5/6852 ,  A61B8/0891 ,  A61B8/12 ,  A61B8/14 ,  A61B8/445 ,  A61B8/4483 ,  A61B8/5207

    摘要： The invention relates to photoacoustic imaging and ultrasound echo imaging In combination, and applies in particular to the field of imaging a lumen of an organ or vessel of a subject, wherein the Images are acquired from within a lumen of the organ or vessel, especially a lumen of a blood vessel to diagnose and treat vascular disease An exemplary embodiment of the invention is a catheter having an ultrasound transducer, the transducer comprising a probe suitable for generating and detecting photoacoustic signals and ultrasound echo signals, wherein the photoacoustic signals and the ultrasound echo signals are convertible to images which are integrated into an enriched image. The photoacoustic signals are generated by a multiplicity of energy sources suitable for inducing the walls of the blood vessel to generate acoustic waves, wherein the energy sources are arrayed in an annulus around the flexible tubular member.

    摘要翻译： 本发明涉及光声成像和超声回波成像组合，并且特别适用于对受试者的器官或血管的内腔进行成像的领域，其中，图像从器官或血管的内腔中获取，特别是 用于诊断和治疗血管疾病的血管腔本发明的示例性实施例是具有超声换能器的导管，所述换能器包括适于产生和检测光声信号和超声波回波信号的探针，其中所述光声信号和所述超声回波 信号可转换为集成到富集图像中的图像。 光声信号由适合于诱导血管壁的多种能量源产生，以产生声波，其中能量排列在围绕柔性管状构件的环形空间中。