摘要:
The present invention provides an imidazopyridine compound represented by formula (I), wherein R1 and R2 each independently represent a C1-6 alkyl group et al; R3 and R4 each independently represent a hydrogen atom, a methyl et al; Ar1 is a divalent substituent representing a monocyclic or bicyclic, 3- to 8-membered aromatic or aliphatic heterocyclic group et al; Ar2 represents an aromatic carbocyclic group, or an aromatic heterocyclic group; W represents —(CH2)m et al, and m indicates an integer of from 0 to 10. This compound acts as a melanin concentrating hormone receptor antagonist, and is useful as treating agents for obesity.
摘要翻译:本发明提供由式(I)表示的咪唑并吡啶化合物,其中R 1和R 2各自独立地表示C 1-6烷基等; R3和R4各自独立地表示氢原子,甲基等; Ar 1是代表单环或双环的3-至8-元芳族或脂族杂环基团的二价取代基; Ar 2表示芳香族碳环基或芳香族杂环基; W表示 - (CH 2)m等,m表示0〜10的整数。该化合物作为黑色素浓缩激素受体拮抗剂起作用,可用作肥胖症的治疗剂。
摘要:
The present invention provides an imidazopyridine compound represented by formula (I), wherein R1 and R2 each independently represent a C1-6 alkyl group et al; R3 and R4 each independently represent a hydrogen atom, a methyl et al; Ar1 is a divalent substituent representing a monocyclic or bicyclic, 3- to 8-membered aromatic or aliphatic heterocyclic group et al; Ar2 represents an aromatic carbocyclic group, or an aromatic heterocyclic group; W represents —(CH2)m et al, and m indicates an integer of from 0 to 10. This compound acts as a melanin concentrating hormone receptor antagonist, and is useful as treating agents for obesity.
摘要翻译:本发明提供由式(I)表示的咪唑并吡啶化合物,其中R 1和R 2各自独立地表示C 1-6烷基 集团等 R 3和R 4各自独立地表示氢原子,甲基等; Ar 1是表示单环或双环的3至8元芳族或脂族杂环基等的二价取代基; Ar 2表示芳族碳环基或芳族杂环基; W表示 - (CH 2)2,m表示0〜10的整数。该化合物作为黑色素浓缩激素受体拮抗剂起作用, 作为肥胖症的治疗剂。
摘要:
The invention provides imidazopyridine derivatives represented by the general formula [I] [in which R1 and R2 may be the same or different and stand for C1-6 alkyl or the like, R3 and R4 stand for hydrogen atom, methyl group or the like, W stands for mono- or bi-cyclic 3- to 8-membered aromatic or aliphatic heterocycle or the like, and Ar stands for optionally substituted aromatic heterocycle or the like]. These compounds act as melanin-concentrating hormone receptor antagonist and are useful as medicines for central nervous system disorders, cardiovascular system disorders and metabolic disorders.
摘要:
The invention provides imidazopyridine derivatives represented by the general formula [I] [in which R1 and R2 may be the same or different and stand for C1-6 alkyl or the like, R3 and R4 stand for hydrogen atom, methyl group or the like, W stands for mono- or bi-cyclic 3- to 8-membered aromatic or aliphatic heterocycle or the like, and Ar stands for optionally substituted aromatic heterocycle or the like]. These compounds act as melanin-concentrating hormone receptor antagonist and are useful as medicines for central nervous system disorders, cardiovascular system disorders and metabolic disorders.
摘要:
A magnetic body is provided to improve heat transport capability and heat transport efficiency. A magnetic body arranged plate has magnetic body units each including magnetic members. Low-temperature side and high-temperature side heat exchange units are disposed at ends of each magnetic body unit. Permanent magnets and heat conductive members are arranged on a magnet/heat conductive member arranged plate. When the magnetic body arranged plate and the magnet/heat conductive member arranged plate are moved relative to each other, the permanent magnets apply magnetism separately to the magnetic members of each magnetic body unit. The magnet/heat conductive member arranged plate creates a temperature difference and conducts heat in one direction between the magnetic members, the low-temperature side heat exchange unit, and the high-temperature side heat exchange unit.
摘要:
A magnetic structure has a magnetocaloric material the temperature of which changes with application or removal of a magnetic field, and a high thermal conduction member which is in contact with the magnetocaloric material and has higher thermal conductivity than the magnetocaloric material. Further, this magnetic air-conditioning and heating device is provided with multiple of the aforementioned magnetic structures, a thermal switch which is arranged between magnetic structures and transmits or insulates heat, and a magnetic field varying unit which applies or removes a magnetic field to each of the magnetic structures. By providing in the magnetic structures a high thermal conduction member with higher thermal conductivity than the magnetocaloric material, some or all of the heat generated in the magnetocaloric material can be quickly conducted in the magnetic bodies.
摘要:
A solid-state image pickup apparatus includes a reading unit having a plurality of pixels connected thereto, holding signals from the pixels, and a control unit capable of controlling operations of the pixels and reading unit. The control unit controls the pixels and reading unit in a first operation mode without addition, in a second operation mode in which signals from aa of the pixels are added, aa being an integer greater than one, and in a third operation mode in which signals from bb of the pixels are added, bb being an integer greater than aa. The reading unit includes a holding unit having a capacitance value of C, and the holding unit includes a first capacitor having a capacitance value of C/bb and a second capacitor having a capacitance value of C/p, p being a common multiple of aa and bb.
摘要:
A low cost and high speed AF sensor is realized by increasing AF speed without providing a sensor dedicated for a large de-focusing AF. The AF sensor has two sensors each including a plurality of photoelectric conversion elements and detects a focus based on signals read from the sensors. The two sensors each includes a plurality of linear sensors 11 to 13. The two sensors each has a plurality of accumulation controlling circuits (PB detection circuits 14 to 16 and accumulation decision circuits 17 to 19) for controlling the accumulation time of the photoelectric conversion elements and a plurality of scanning circuits (shift registers 21 to 23) for reading out output signals from the photoelectric conversion elements. The AF sensor has a first mode in which the accumulation time of each linear sensor in the two sensors is independently controlled to independently read a signal output and a second mode in which the accumulation time of the linear sensors in the two sensors is collectively controlled to read a signal output.
摘要:
The present invention provides a semiconductor device having a structure that can be mounted on a wiring substrate, as for the semiconductor device formed over a thin film-thickness substrate, a film-shaped substrate, or a sheet-like substrate. In addition, the present invention provides a method for manufacturing a semiconductor device that is capable of raising a reliability of mounting on a wiring substrate. One feature of the present invention is to bond a semiconductor element formed on a substrate having isolation to a member that a conductive film is formed via a medium having an anisotropic conductivity.
摘要:
Techniques are provided for obtaining a photoelectric conversion device having a favorable spectral sensitivity characteristic and reduced variation in output current without a contamination substance mixed into a photoelectric conversion layer or a transistor, and for obtaining a highly reliable semiconductor device including a photoelectric conversion device. A semiconductor device may include, over an insulating surface, a first electrode; a second electrode; a color filter between the first electrode and the second electrode; an overcoat layer covering the color filter; and a photoelectric conversion layer over the overcoat layer, where one end portion of the photoelectric conversion layer is in contact with the first electrode, and where an end portion of the color filter lies inside the other end portion of the photoelectric conversion layer.