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公开(公告)号:US08414845B2
公开(公告)日:2013-04-09
申请号:US12871478
申请日:2010-08-30
申请人: Shuqi Chen , Bertrand Lemieux , Lingjun Chen
发明人: Shuqi Chen , Bertrand Lemieux , Lingjun Chen
IPC分类号: G01N21/75
CPC分类号: B01L3/502 , B01L3/505 , B01L7/52 , B01L2200/0647 , B01L2200/10 , B01L2300/0681 , B01L2300/0809 , B01L2300/0864 , B01L2300/0867 , B01L2300/087 , B01L2300/123 , B01L2400/0481 , B01L2400/0683 , Y10T436/25
摘要: A sample processing vessel may include a branch segment and at least two tracks. The at least two tracks may be fluidly isolated from one another by a permanent seal. The tracks may be segmented by breakable seals. The branch segment may be temporarily isolated from the tracks by breakable seal(s) and put in fluid communication with the tracks once those seal(s) are broken, such that fluid received by the branch segment is divided into portions that pass into both tracks.
摘要翻译: 样品处理容器可以包括分支段和至少两个轨道。 至少两个轨道可以通过永久密封件彼此流体地隔离。 轨道可以由可破坏的密封件分段。 分支段可以通过可破坏的密封件与轨道暂时隔离,一旦这些密封件被破坏就将其与轨道流体连通,使得由分支段接收的流体被分成两个轨道的部分 。
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公开(公告)号:US07785535B2
公开(公告)日:2010-08-31
申请号:US11570184
申请日:2005-06-07
申请人: Shuqi Chen , Bertrand Lemieux , Lingjun Chen
发明人: Shuqi Chen , Bertrand Lemieux , Lingjun Chen
CPC分类号: B01L3/502 , B01L3/505 , B01L7/52 , B01L2200/0647 , B01L2200/10 , B01L2300/0681 , B01L2300/0809 , B01L2300/0864 , B01L2300/0867 , B01L2300/087 , B01L2300/123 , B01L2400/0481 , B01L2400/0683 , Y10T436/25
摘要: A sample processing cartridge may include a plurality of segments arranged in an array at least two rows long and two columns wide. Each segment may be defined by at least one wall of the sample cartridge, fluidly isolated from adjacent segments at least in part by at least one breakable seal or by at least one permanent seal, so expandable as to receive a volume of fluid expelled from another segment, and so compressible as to contain substantially no fluid when so compressed. At least two adjacent segments of at least one row of the array may be aligned along a longitudinal axis of the row and have substantially the same height along a latitudinal axis of the row. At least two adjacent segments in at least one row may be separated by a permanent seal to form at least two tracks. At least one segment, or at least two adjacent segments separated by a breakable seal, may be in fluid communication with the at least two tracks. At least one segment may contain at least one reagent.
摘要翻译: 样品处理盒可以包括以至少两行长和两列宽排列成阵列的多个片段。 每个段可以由样品盒的至少一个壁限定,至少部分地由相邻节段隔离,至少一个可破坏的密封件或通过至少一个永久性密封件,该密封件可膨胀以接收从另一个排出的一定体积的流体 片段,并且如此可压缩,以便在被压缩时基本上不含流体。 阵列的至少一排的至少两个相邻的段可以沿着该行的纵向轴线对准,并且沿着行的纬度轴线具有基本上相同的高度。 至少一行中的至少两个相邻的区段可以通过永久密封件分开以形成至少两个轨道。 由可破坏的密封件分开的至少一个段或至少两个相邻的段可以与至少两个轨道流体连通。 至少一个片段可以含有至少一种试剂。
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公开(公告)号:US20100323919A1
公开(公告)日:2010-12-23
申请号:US12871478
申请日:2010-08-30
申请人: Shuqi Chen , Bertrand Lemieux , Lingjun Chen
发明人: Shuqi Chen , Bertrand Lemieux , Lingjun Chen
CPC分类号: B01L3/502 , B01L3/505 , B01L7/52 , B01L2200/0647 , B01L2200/10 , B01L2300/0681 , B01L2300/0809 , B01L2300/0864 , B01L2300/0867 , B01L2300/087 , B01L2300/123 , B01L2400/0481 , B01L2400/0683 , Y10T436/25
摘要: A sample processing vessel may include a branch segment and at least two tracks. The at least two tracks may be fluidly isolated from one another by a permanent seal. The tracks may be segmented by breakable seals. The branch segment may be temporarily isolated from the tracks by breakable seal(s) and put in fluid communication with the tracks once those seal(s) are broken, such that fluid received by the branch segment is divided into portions that pass into both tracks.
摘要翻译: 样品处理容器可以包括分支段和至少两个轨道。 至少两个轨道可以通过永久密封件彼此流体地隔离。 轨道可以由可破坏的密封件分段。 分支段可以通过可破坏的密封件与轨道暂时隔离,一旦这些密封件被破坏就将其与轨道流体连通,使得由分支段接收的流体被分成两个轨道的部分 。
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公开(公告)号:US07718421B2
公开(公告)日:2010-05-18
申请号:US10773775
申请日:2004-02-05
申请人: Shuqi Chen , Bertrand Lemieux , Zihua Wang , Kevin R. Kopczynski , Lingjun Chen
发明人: Shuqi Chen , Bertrand Lemieux , Zihua Wang , Kevin R. Kopczynski , Lingjun Chen
IPC分类号: C12M1/36
CPC分类号: C12N15/1003 , B01L3/502 , B01L3/505 , B01L2200/0621 , B01L2200/10 , B01L2300/042 , B01L2300/046 , B01L2300/047 , B01L2300/0681 , B01L2300/069 , B01L2300/087 , B01L2300/10 , B01L2400/0481 , B01L2400/0677 , G01N1/10 , G01N33/543 , Y02A50/52 , Y02A50/53 , Y02A50/55 , Y02A50/58 , Y02A50/60 , Y10S435/81 , Y10T436/25
摘要: A sample processing tubule may include a first segment, a second segment, and a third segment. Each segment may be defined by the tubule, may be fluidly isolated, at least in part by a breakable seal, may be so expandable as to receive a volume of fluid expelled from another segment, and may be so compressible as to contain substantially no fluid when so compressed. Each segment may contain at least one reagent.
摘要翻译: 样本处理小管可以包括第一段,第二段和第三段。 每个段可以由小管限定,至少部分地通过可破坏的密封件被流体隔离,可以是如此可扩张的,以便接收从另一个部分排出的体积的体积,并且可以是如此可压缩的,从而基本上不含流体 当这样压缩。 每个片段可以含有至少一种试剂。
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公开(公告)号:US20070292858A1
公开(公告)日:2007-12-20
申请号:US11570184
申请日:2005-06-07
申请人: Shuqi Chen , Bertrand Lemieux , Lingjun Chen
发明人: Shuqi Chen , Bertrand Lemieux , Lingjun Chen
CPC分类号: B01L3/502 , B01L3/505 , B01L7/52 , B01L2200/0647 , B01L2200/10 , B01L2300/0681 , B01L2300/0809 , B01L2300/0864 , B01L2300/0867 , B01L2300/087 , B01L2300/123 , B01L2400/0481 , B01L2400/0683 , Y10T436/25
摘要: A sample processing cartridge may include a plurality of segments arranged in an array at least two rows long and two columns wide. Each segment may be defined by at least one wall of the sample cartridge, fluidly isolated from adjacent segments at least in part by at least one breakable seal or by at least one permanent seal, so expandable as to receive a volume of fluid expelled from another segment, and so compressible as to contain substantially no fluid when so compressed. At least two adjacent segments of at least one row of the array may be aligned along a longitudinal axis of the row and have substantially the same height along a latitudinal axis of the row. At least two adjacent segments in at least one row may be separated by a permanent seal to form at least two tracks. At least one segment, or at least two adjacent segments separated by a breakable seal, may be in fluid communication with the at least two tracks. At least one segment may contain at least one reagent.
摘要翻译: 样品处理盒可以包括以至少两行长和两列宽排列成阵列的多个片段。 每个段可以由样品盒的至少一个壁限定,至少部分地由相邻节段隔离,至少一个可破坏的密封件或通过至少一个永久性密封件,该密封件可膨胀以接收从另一个排出的一定体积的流体 片段,并且如此可压缩,以便在被压缩时基本上不含有流体。 阵列的至少一排的至少两个相邻的段可以沿着该行的纵向轴线对准,并且沿着行的纬度轴线具有基本上相同的高度。 至少一行中的至少两个相邻的区段可以通过永久密封件分开以形成至少两个轨道。 由可破坏的密封件分开的至少一个段或至少两个相邻的段可以与至少两个轨道流体连通。 至少一个片段可以含有至少一种试剂。
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公开(公告)号:US20050208570A1
公开(公告)日:2005-09-22
申请号:US11125588
申请日:2005-05-09
CPC分类号: C07H21/04 , C07H21/02 , C12Q1/6827 , C12Q1/6895 , C12Q2600/158
摘要: The invention provides oligonucleotides and their complements that can be used as allele-specific probes or primers for sequencing, oligonucleotide probe hybridization, and allele-specific amplification. Such oligonucleotides can be used, for example, to facilitate genetic distinction between individual plants in plant populations.
摘要翻译: 本发明提供可用作等位基因特异性探针或引物用于测序,寡核苷酸探针杂交和等位基因特异性扩增的寡核苷酸及其互补序列。 这样的寡核苷酸可用于例如促进植物种群中各植物之间的遗传区别。
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公开(公告)号:US06358686B1
公开(公告)日:2002-03-19
申请号:US09464453
申请日:1999-12-14
IPC分类号: C12Q168
CPC分类号: C12Q1/6895 , C12Q2600/158
摘要: The invention provides oligonucleotides and their complements that can be used as allele-specific probes or primers for sequencing, oligonucleotide probe hybridization, and allele-specific amplification. Such oligonucleotides can be used, for example, to facilitate genetic distinction between individual plants in plant populations.
摘要翻译: 本发明提供可用作等位基因特异性探针或引物用于测序,寡核苷酸探针杂交和等位基因特异性扩增的寡核苷酸及其互补序列。 这样的寡核苷酸可用于例如促进植物种群中各植物之间的遗传区别。
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公开(公告)号:US06114116A
公开(公告)日:2000-09-05
申请号:US813507
申请日:1997-03-07
CPC分类号: C12Q1/6827 , C12Q1/6895 , C12Q2600/156
摘要: The invention provides oligonucleotides and their complements that can be used as allele-specific probes or primers for sequencing, oligonucleotide probe hybridization, and allele-specific amplification. Such oligonucleotides can be used, for example, to facilitate genetic distinction between individual plants in plant populations.
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