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公开(公告)号：US11016062B2
公开(公告)日：2021-05-25
申请号：US16722210
申请日：2019-12-20
IPC分类号： G01N29/02 , G01N29/036 , G01N29/22 , G01N29/24 , G01N33/48
摘要： A novel SH-SAW biosensor capable of non-invasive and touch-free detection of cancer cell viability and growth or proliferation in two-dimensional (2D) and three-dimensional (3D) cell cultures as well as stem cell regeneration as it pertains to cancer cell biology and anti-cancer drug development is presented. The biosensor includes two pairs of resonators including interdigital transducers reflecting fingers to quantify mass loading by the cells in suspension as well as within a tumoroid culture platform. The biosensor can be part of a perfused 3PNS-tumoroid system that is amenable to real-time non-invasive monitoring of the cell proliferation, viability, and multiplexed detection of key physiologic and clinical biomarkers.
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公开(公告)号：US10520472B2
公开(公告)日：2019-12-31
申请号：US15682070
申请日：2017-08-21
IPC分类号： G01N29/02 , G01N29/036 , G01N33/48 , G01N29/24 , G01N29/22
摘要： A novel SH-SAW biosensor capable of non-invasive and touch-free detection of cancer cell viability and growth or proliferation in two-dimensional (2D) and three-dimensional (3D) cell cultures as well as stem cell regeneration as it pertains to cancer cell biology and anti-cancer drug development is presented. The biosensor includes two pairs of resonators including interdigital transducers reflecting fingers to quantify mass loading by the cells in suspension as well as within a tumoroid culture platform. The biosensor can be part of a perfused 3PNS-tumoroid system that is amenable to real-time non-invasive monitoring of the cell proliferation, viability, and multiplexed detection of key physiologic and clinical biomarkers.
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公开(公告)号：US09518192B2
公开(公告)日：2016-12-13
申请号：US14131071
申请日：2011-07-05
申请人： James C. Bohling , Deborah G. Fradkin , Wei Gao , John W. Hook, III , Tao Wang , Tao Wang
发明人： James C. Bohling , Deborah G. Fradkin , Wei Gao , John W. Hook, III , Tao Wang , Tao Wang
IPC分类号： C08J3/215 , C08K3/22 , C09D133/08 , C09C1/36 , C09D135/06 , C09D5/02 , C09D7/12 , C09D7/14 , C08K3/20
CPC分类号： C09D133/08 , C01P2004/62 , C08K3/20 , C08K3/22 , C08K2003/2241 , C09C1/3676 , C09D5/028 , C09D7/61 , C09D7/80 , C09D135/06
摘要： The present invention relates to a process comprising the steps of a) contacting an aqueous dispersion of a TiO2 slurry containing adsorbing dispersant with an adsorbing latex to form a mixture, wherein the pH of the mixture of the TiO2 slurry and adsorbing latex are sufficiently high to inhibit interaction between the TiO2 and the adsorbing latex; then b) lowering the pH of the mixture of step a) sufficiently to promote interaction between the TiO2 and the adsorbing latex, thereby forming a composite. The process of the present invention provides for improved hiding and reduced grit for coatings compositions.
摘要翻译： 本发明涉及一种方法，包括以下步骤：a）将含有吸附分散剂的TiO 2浆料的水性分散体与吸附胶乳接触以形成混合物，其中TiO 2浆料和吸附胶乳的混合物的pH足够高至 抑制TiO 2和吸附胶乳之间的相互作用; 然后b）降低步骤a）的混合物的pH足以促进TiO 2和吸附胶乳之间的相互作用，从而形成复合材料。 本发明的方法提供了改进的涂层组合物的隐藏和减小的砂砾。
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公开(公告)号：US09303182B2
公开(公告)日：2016-04-05
申请号：US14405835
申请日：2012-06-05
申请人： Tao Wang , Junyu Chen , Tao Wang , Yujiang Wang , Longlan Cui
发明人： Tao Wang , Junyu Chen , Tao Wang , Yujiang Wang , Longlan Cui
IPC分类号： C08K9/00 , C09D133/14 , C09D151/00 , C08K3/22 , C08K3/36 , C09D125/14 , C09D131/04
CPC分类号： C09D133/14 , C08K3/22 , C08K3/36 , C08K2003/2241 , C09D125/14 , C09D131/04 , C09D151/003
摘要： This invention relates to a coating composition, especially, relates to an aqueous coating composition with improved stability.
摘要翻译： 本发明涉及涂料组合物，特别涉及具有改进稳定性的水性涂料组合物。
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公开(公告)号：US20160083908A1
公开(公告)日：2016-03-24
申请号：US14786997
申请日：2013-05-22
申请人： Tao WANG , Weichao GU , Tao WANG , Junyu CHEN , Haitao DU , Yunfei YAN , Rui MA , Dow Global Technologies LLC , ROHM AND HAAS COMPANY
发明人： Tao Wang , Weichao Gu , Tao Wang , Junyu Chen , Haitao Du , Rui Ma , Yunfei Yan
摘要： A new paper composition comprising, a) from 15 wt. % to 70 wt. % a hiding composite comprising based on the total weight of the hiding composite, from 30 wt. % to 75 wt. % pigment particles and from 25 wt. % to 70 wt. % a thermoplastic polymer. The pigment particles are hydrophobically treated with the surface tension of the pigment particles being from 0.1 to 50 mN/m, and the surface tension difference between the pigment particles and the thermoplastic polymer being less than 40 mN/m; and b) from 30 wt. % to 85 wt. % a paper pulp. Process of making such a new paper composition.
摘要翻译： 一种新的纸组合物，其包含a）15wt。 ％至70wt。 ％的隐藏复合材料，其基于所述隐藏复合材料的总重量为30重量％ ％至75wt。 ％颜料颗粒和25重量％ ％至70wt。 ％热塑性聚合物。 颜料颗粒被疏水处理，颜料颗粒的表面张力为0.1-50mN / m，颜料颗粒和热塑性聚合物之间的表面张力差小于40mN / m; 和b）30wt。 ％〜85重量％ ％纸浆。 制作这样一种新的纸张组合的过程。
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公开(公告)号：US08987350B2
公开(公告)日：2015-03-24
申请号：US13564872
申请日：2012-08-02
申请人： Juan Li , Tao Wang , Tao Wang , David G. Speece, Jr.
发明人： Juan Li , Tao Wang , Tao Wang , David G. Speece, Jr.
CPC分类号： C09D5/028 , C08K9/10 , C08L91/08 , C09D5/1637 , C09D7/62 , C09D7/65 , C09D191/06
摘要： The present invention relates to a coating composition, especially, relates to an aqueous coating composition with improved liquid stain repellency, it has a fraction of critical pigment volume concentration of from 35% to 110%, and comprises (i) pigment composition, including 15 wt. %-100 wt. %, in percentage by weight based on the dry weight of the pigment composition, polymer-encapsulated pigment; and 0-85 wt. %, in percentage by weight based on the dry weight of the pigment composition, un-encapsulated pigment; and (ii) 0.01 wt. %-5 wt. %, in percentage by dry weight based on the wet weight of the aqueous coating composition, at least one paraffin wax emulsion.
摘要翻译： 本发明涉及一种涂料组合物，特别涉及具有改善的液体防污性的水性涂料组合物，其具有35％至110％的临界颜料体积浓度的一部分，并且包含（i）颜料组合物，包括15 重量 ％-100wt。 ％，以颜料组合物的干重为基准的重量百分比，聚合物包封的颜料; 和0-85wt。 ％，以颜料组合物的干重为基准的重量百分数，未包封的颜料; 和（ii）0.01重量％ ％-5wt。 ％，以干重计，基于水性涂料组合物的湿重，至少一种石蜡乳液。
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公开(公告)号：US20150025172A1
公开(公告)日：2015-01-22
申请号：US14131071
申请日：2011-07-05
申请人： James C. Bohling , Deborah G. Fradkin , Wei Gao , John W. Hook, III , Tao Wang , Tao Wang
发明人： James C. Bohling , Deborah G. Fradkin , Wei Gao , John W. Hook, III , Tao Wang , Tao Wang
IPC分类号： C09D133/08 , C08K3/20 , C08K3/22 , C09D7/12
CPC分类号： C09D133/08 , C01P2004/62 , C08K3/20 , C08K3/22 , C08K2003/2241 , C09C1/3676 , C09D5/028 , C09D7/61 , C09D7/80 , C09D135/06
摘要： The present invention relates to a process comprising the steps of a) contacting an aqueous dispersion of a TiO2 slurry containing adsorbing dispersant with an adsorbing latex to form a mixture, wherein the pH of the mixture of the TiO2 slurry and adsorbing latex are sufficiently high to inhibit interaction between the TiO2 and the adsorbing latex; then b) lowering the pH of the mixture of step a) sufficiently to promote interaction between the TiO2 and the adsorbing latex, thereby forming a composite. The process of the present invention provides for improved hiding and reduced grit for coatings compositions.
摘要翻译： 本发明涉及一种方法，包括以下步骤：a）将含有吸附分散剂的TiO 2浆料的水性分散体与吸附胶乳接触以形成混合物，其中TiO 2浆料和吸附胶乳的混合物的pH足够高至 抑制TiO 2和吸附胶乳之间的相互作用; 然后b）降低步骤a）的混合物的pH足以促进TiO 2和吸附胶乳之间的相互作用，从而形成复合材料。 本发明的方法提供了改进的涂层组合物的隐藏和减小的砂砾。
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公开(公告)号：US20210284615A1
公开(公告)日：2021-09-16
申请号：US16319750
申请日：2017-07-24
申请人： Qingeng LI , Tao Wang , Jian Liao , Xiangqing XU , Liang Ren
发明人： Qingeng LI , Tao Wang , Jian Liao , Xiangqing XU , Liang Ren
IPC分类号： C07D295/096 , A61P25/24 , C07D295/205 , C07D295/185 , C07D295/192 , C07C321/26 , C07C319/02
摘要： The present disclosure relates to a new type of vortioxetine analogue of Formula I or its polymorph or a solvate, a composition, and a kit comprising the analogue, the polymorph or the solvate, and the use of the compound or the polymorph or the solvate, or the composition in the preparation of a medicament for the treatment of depression. The methods of preparation of the analogues and intermediate compounds are also described.
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