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公开(公告)号:US20050058747A1
公开(公告)日:2005-03-17
申请号:US10873593
申请日:2004-06-21
IPC分类号: A23K3/00 , C07H21/04 , C11D3/386 , C12N9/08 , C12N9/52 , C12N9/54 , C12N9/58 , C12N15/57 , C12N15/74
CPC分类号: C12N9/52 , A01K2217/05 , C12N9/58 , C12N2310/111
摘要: The present invention relates to thermostable proteases homologous to proteases derived from Nocardiopsis, and the production thereof by the wild-type, and in recombinant host cells including transgenic plants and non-human transgenic animals. The proteases are effective in animal feed, in particular fish feed, and detergents. The proteases are capable of degrading the soybean Bowman-Birk inhibitor, and other antinutritional factors such as soybean agglutinin and the Kunitz trypsin inhibitor, as well as the isolated soy storage proteins glycinin and beta-conglycinin. Characteristic structural features of relevance for the thermostability of these proteases of peptidase family S2A or S1E are disclosed.
摘要翻译: 本发明涉及与来源于诺卡氏菌属的蛋白酶同源的热稳定蛋白酶,以及野生型的生产,以及包含转基因植物和非人转基因动物的重组宿主细胞。 蛋白酶在动物饲料,特别是鱼饲料和洗涤剂中是有效的。 蛋白酶能够降解大豆Bowman-Birk抑制剂和其他抗营养因子如大豆凝集素和Kunitz胰蛋白酶抑制剂,以及分离的大豆贮存蛋白大豆球蛋白和β-伴大豆球蛋白。 公开了与肽酶家族S2A或S1E的这些蛋白酶的热稳定性相关的特征性结构特征。
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公开(公告)号:US07179630B2
公开(公告)日:2007-02-20
申请号:US10873593
申请日:2004-06-21
申请人: Soeren Flensted Lassen , Carsten Sjoeholm , Peter Rahbek Oestergaard , Carsten Andersen , Morten Fischer
发明人: Soeren Flensted Lassen , Carsten Sjoeholm , Peter Rahbek Oestergaard , Carsten Andersen , Morten Fischer
CPC分类号: C12N9/52 , A01K2217/05 , C12N9/58 , C12N2310/111
摘要: The present invention relates to thermostable proteases having an amino acid sequence which homologous to the amino acid sequence of proteases derived from Nocardiopsis, and the production thereof by wild-type and recombinant host cells including transgenic plants and non-human transgenic animals. The proteases are effective in animal feed, in particular fish feed, and detergents. The proteases are capable of degrading the soybean Bowman-Birk inhibitor, and other antinutritional factors such as soybean agglutinin and the Kunitz trypsin inhibitor, as well as the isolated soy storage proteins glycinin and beta-conglycinin. Characteristic structural features of relevance for the thermostability of these proteases of peptidase family S2A or S1E are disclosed.
摘要翻译: 本发明涉及具有与来自诺卡氏菌属(Nocardiopsis)的蛋白酶的氨基酸序列同源的氨基酸序列的热稳定蛋白酶,以及包含转基因植物和非人转基因动物的野生型和重组宿主细胞的生产。 蛋白酶在动物饲料,特别是鱼饲料和洗涤剂中是有效的。 蛋白酶能够降解大豆Bowman-Birk抑制剂和其他抗营养因子如大豆凝集素和Kunitz胰蛋白酶抑制剂,以及分离的大豆贮存蛋白大豆球蛋白和β-伴大豆球蛋白。 公开了与肽酶家族S2A或S1E的这些蛋白酶的热稳定性相关的特征性结构特征。
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公开(公告)号:US20080286415A1
公开(公告)日:2008-11-20
申请号:US11570913
申请日:2005-06-17
IPC分类号: A23K1/165 , C12N9/50 , C12N15/11 , C12N15/00 , C12N5/06 , C12N5/04 , A01H5/00 , A01K67/027 , C12P21/04 , C12N1/20
CPC分类号: C12N9/52 , A23J3/346 , A23K20/189 , A23K50/30 , A23K50/60 , A23K50/75 , C11D3/38609 , C11D3/38618
摘要: Proteases derived from Nocardiopsis dassonvillei subsp. dassonvillei DSM 43235, Nocardiopsis prasina DSM 15649, Nocardiopsis prasina (previously alba) DSM 14010 Nocardiopsis sp. DSM 16424, Nocardiopsis alkaliphila DSM 44657 and Nocardiopsis lucentensis DSM 44048, as well as homologous proteases; their recombinant production in various hosts, including transgenic plants and non-human animals, and their use in animal feed and detergents. The proteases are acid-stable, alkali-stable, and/or thermostable.
摘要翻译: 衍生自Nocardiopsis dassonvillei subsp。 dassonvillei DSM 43235,Nocardiopsis prasina DSM 15649,Nocardiopsis prasina(以前的alba)DSM 14010 Nocardiopsis sp。 DSM 16424,Nocardiopsis alkaliphila DSM 44657和Nocardiopsis lucentensis DSM 44048以及同源蛋白酶; 其在各种宿主中的重组生产,包括转基因植物和非人类动物,以及它们在动物饲料和洗涤剂中的应用。 蛋白酶是酸稳定的,碱稳定的和/或热稳定的。
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公开(公告)号:US09279115B2
公开(公告)日:2016-03-08
申请号:US13490566
申请日:2012-06-07
CPC分类号: C12N9/52 , A23J3/346 , A23K20/189 , A23K50/30 , A23K50/60 , A23K50/75 , C11D3/38609 , C11D3/38618
摘要: Proteases derived from Nocardiopsis dassonvillei subsp. dassonvillei DSM 43235, Nocardiopsis prasina DSM 15649, Nocardiopsis prasina (previously alba) DSM 14010 Nocardiopsis sp. DSM 16424, Nocardiopsis alkaliphila DSM 44657 and Nocardiopsis lucentensis DSM 44048, as well as homologous proteases; their recombinant production in various hosts, including transgenic plants and non-human animals, and their use in animal feed and detergents. The proteases are acid-stable, alkali-stable, and/or thermostable.
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公开(公告)号:US20120321747A1
公开(公告)日:2012-12-20
申请号:US13490566
申请日:2012-06-07
CPC分类号: C12N9/52 , A23J3/346 , A23K20/189 , A23K50/30 , A23K50/60 , A23K50/75 , C11D3/38609 , C11D3/38618
摘要: Proteases derived from Nocardiopsis dassonvillei subsp. dassonvillei DSM 43235, Nocardiopsis prasina DSM 15649, Nocardiopsis prasina (previously alba) DSM 14010 Nocardiopsis sp. DSM 16424, Nocardiopsis alkaliphila DSM 44657 and Nocardiopsis lucentensis DSM 44048, as well as homologous proteases; their recombinant production in various hosts, including transgenic plants and non-human animals, and their use in animal feed and detergents. The proteases are acid-stable, alkali-stable, and/or thermostable.
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公开(公告)号:US09279114B2
公开(公告)日:2016-03-08
申请号:US13490559
申请日:2012-06-07
CPC分类号: C12N9/52 , A23J3/346 , A23K20/189 , A23K50/30 , A23K50/60 , A23K50/75 , C11D3/38609 , C11D3/38618
摘要: Proteases derived from Nocardiopsis dassonvillei subsp. dassonvillei DSM 43235, Nocardiopsis prasina DSM 15649, Nocardiopsis prasina (previously alba) DSM 14010 Nocardiopsis sp. DSM 16424, Nocardiopsis alkaliphila DSM 44657 and Nocardiopsis lucentensis DSM 44048, as well as homologous proteases; their recombinant production in various hosts, including transgenic plants and non-human animals, and their use in animal feed and detergents. The proteases are acid-stable, alkali-stable, and/or thermostable.
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公开(公告)号:US20120321746A1
公开(公告)日:2012-12-20
申请号:US13490559
申请日:2012-06-07
IPC分类号: C12N9/52 , C12N15/57 , C12N15/63 , A23K1/165 , C12N5/10 , C12N1/15 , C12N1/19 , C12S3/14 , C12N1/21
CPC分类号: C12N9/52 , A23J3/346 , A23K20/189 , A23K50/30 , A23K50/60 , A23K50/75 , C11D3/38609 , C11D3/38618
摘要: Proteases derived from Nocardiopsis dassonvillei subsp. dassonvillei DSM 43235, Nocardiopsis prasina DSM 15649, Nocardiopsis prasina (previously alba) DSM 14010 Nocardiopsis sp. DSM 16424, Nocardiopsis alkaliphila DSM 44657 and Nocardiopsis lucentensis DSM 44048, as well as homologous proteases; their recombinant production in various hosts, including transgenic plants and non-human animals, and their use in animal feed and detergents. The proteases are acid-stable, alkali-stable, and/or thermostable.
摘要翻译: 衍生自Nocardiopsis dassonvillei subsp。 dassonvillei DSM 43235,Nocardiopsis prasina DSM 15649,Nocardiopsis prasina(以前的alba)DSM 14010 Nocardiopsis sp。 DSM 16424,Nocardiopsis alkaliphila DSM 44657和Nocardiopsis lucentensis DSM 44048以及同源蛋白酶; 其在各种宿主中的重组生产,包括转基因植物和非人类动物,以及它们在动物饲料和洗涤剂中的应用。 蛋白酶是酸稳定的,碱稳定的和/或热稳定的。
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公开(公告)号:US09668501B2
公开(公告)日:2017-06-06
申请号:US12307997
申请日:2007-07-12
CPC分类号: A23K50/10 , A23K10/14 , A23K10/37 , Y02P60/877
摘要: The invention relates to the use of at least one bacterial amylase in feed for ruminant animals of the subfamily Bovinae in particular for improving milk yield, apparent digestibility of the diet fed, feedstuff dry matter disappearance, weight gain, and/or Feed Conversion Ratio (FCR). Examples of bovine animals are dairy cows and beef cattle. The invention also relates to the use of such amylases in feed and feed additives such as premix, concentrates and total mixed ration (TMR). The amylase may be used in combination with cellulase for improving milk yield and/or back fat thickness. Preferred amylases are derived from Bacillus halmapalus, licheniformis, and stearothermophilus and are preferably homologous to Bacillus stearothermophilus amylase.
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公开(公告)号:US08357408B2
公开(公告)日:2013-01-22
申请号:US11570913
申请日:2005-06-17
IPC分类号: A23K1/165
CPC分类号: C12N9/52 , A23J3/346 , A23K20/189 , A23K50/30 , A23K50/60 , A23K50/75 , C11D3/38609 , C11D3/38618
摘要: Proteases derived from Nocardiopsis dassonvillei subsp. dassonvillei DSM 43235, Nocardiopsis prasina DSM 15649, Nocardiopsis prasina (previously alba) DSM 14010 Nocardiopsis sp. DSM 16424, Nocardiopsis alkaliphila DSM 44657 and Nocardiopsis lucentensis DSM 44048, as well as homologous proteases; their recombinant production in various hosts, including transgenic plants and non-human animals, and their use in animal feed and detergents. The proteases are acid-stable, alkali-stable, and/or thermostable.
摘要翻译: 衍生自Nocardiopsis dassonvillei subsp。 dassonvillei DSM 43235,Nocardiopsis prasina DSM 15649,Nocardiopsis prasina(以前的alba)DSM 14010 Nocardiopsis sp。 DSM 16424,Nocardiopsis alkaliphila DSM 44657和Nocardiopsis lucentensis DSM 44048以及同源蛋白酶; 其在各种宿主中的重组生产,包括转基因植物和非人类动物,以及它们在动物饲料和洗涤剂中的应用。 蛋白酶是酸稳定的,碱稳定的和/或热稳定的。
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公开(公告)号:US20100040595A1
公开(公告)日:2010-02-18
申请号:US12441627
申请日:2007-09-27
申请人: Morten Fischer , Dan Pettersson
发明人: Morten Fischer , Dan Pettersson
CPC分类号: C12N9/248 , A23K10/14 , A23K20/189 , C12N9/2482 , C12Y302/01004 , C12Y302/01006 , C12Y302/01008
摘要: The present invention relates to the use in animal feed of a xylanase having a percentage of identity to a Paenibacillus xylanase having the sequence of amino acids 1-184 of SEQ ID NO: 4 of at least 82.7%, as well as to feed additives and feed compositions comprising such xylanase. These xylanases are significantly better than known animal feed xylanases to solubilize and also degrade insoluble fibre polysaccharides (Non-Starch Polysaccharides, abbreviated NSP), such as arabinoxylan polysaccharides.
摘要翻译: 本发明涉及在具有至少82.7%的具有SEQ ID NO:4的氨基酸1-184的序列的木霉菌木聚糖酶的同一性百分比的木聚糖酶的动物饲料中的用途,以及饲料添加剂和 包含这种木聚糖酶的饲料组合物。 这些木聚糖酶明显优于已知的动物饲料木聚糖酶以溶解并降解不溶性纤维多糖(非淀粉多糖,缩写为NSP),例如阿拉伯木聚糖多糖。
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