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公开(公告)号：US20080053437A1
公开(公告)日：2008-03-06
申请号：US11934643
申请日：2007-11-02
申请人： Solomon Steiner , Robert Feldstein , Per Fog , Trent Poole
发明人： Solomon Steiner , Robert Feldstein , Per Fog , Trent Poole
IPC分类号： A61M15/00
CPC分类号： A61M15/003 , A61M13/00 , A61M15/002 , A61M15/0021 , A61M15/0023 , A61M15/0025 , A61M15/0028 , A61M15/0043 , A61M16/0495 , A61M16/0825 , A61M2202/064 , A61M2205/43 , F16L37/252
摘要： Described is a dry powder inhaler comprising an intake section; a mixing section, and a mouthpiece. The mouthpiece is connected by a swivel joint to the mixing section, and may swivel back onto the intake section and be enclosed by a cover. The intake chamber comprises a special piston with a tapered piston rod and spring, and one or more bleed-through orifices to modulate the flow of air through the device. The intake chamber further optionally comprises a feedback module to generate a tone indicating to the user when the proper rate of airflow has been achieved. The mixing section holds a capsule with holes containing a dry powder medicament, and the cover only can open when the mouthpiece is at a certain angle to the intake section. The mixing section further opens and closes the capsule when the intake section is at a certain angle to the mouthpiece. The mixing section is a Venturi chamber configured by protrusions or spirals to impart a cyclonic flow to air passing through the mixing chamber. The mouthpiece includes a tongue depressor, and a protrusion to contact the lips of the user to tell the user that the DPI is in the correct position. An optional storage section, with a cover, holds additional capsules. The cover for the mouthpiece, and the cover for the storage section may both be transparent, magnifying lenses. The capsules may be two-part capsules where each portion has apertures which correspond to apertures in the other half when each half is partially fitted to the other half, and fully fitted to the other half. All the apertures may be closed when the two halves are rotated around their longitudinal axes with respect to each other. Each capsule may have a unique key on each half that only fits with a particular inhaler.
摘要翻译： 描述了一种干粉吸入器，其包括进气段; 混合部分和喉舌。 接口通过旋转接头连接到混合部分，并且可以旋转回到进气部分并被盖封闭。 进气室包括具有锥形活塞杆和弹簧的特殊活塞，以及一个或多个渗流孔口，用于调节通过该装置的空气流。 进气室还可选地包括反馈模块，以产生当达到适当的气流速率时向用户指示的音调。 混合部分容纳具有含有干粉药物的孔的胶囊，并且仅当吸嘴与进气部分成一定角度时，盖子才能打开。 当进气部分与嘴件成一定角度时，混合部分进一步打开和关闭胶囊。 混合部分是由突起或螺旋构成的文丘里室，以使气流通过混合室。 接口管包括舌形按压器和用于接触用户嘴唇的突起，以告诉用户DPI处于正确的位置。 带有盖子的可选存储部分可容纳另外的胶囊。 用于接口管的盖和用于存储部的盖可以都是透明的放大镜。 胶囊可以是两部分胶囊，其中每个部分具有对应于另一半中的孔的孔，当每个半部分部分地配合到另一半时，并且完全配合到另一半。 当两个半部相对于彼此的纵向轴线旋转时，所有的孔可以被关闭。 每个胶囊可以在每一半上具有仅与特定吸入器配合的唯一键。
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公开(公告)号：US20070151623A1
公开(公告)日：2007-07-05
申请号：US11601986
申请日：2006-11-20
申请人： Trent Poole , David Bonneau , Per Fog
发明人： Trent Poole , David Bonneau , Per Fog
IPC分类号： B65B3/26
摘要： Powder dispensing and sensing apparatus and methods are provided. The powder dispensing and sensing apparatus includes a tray support structure to receive a cartridge tray holding cartridges, a powder dispenser assembly including powder dispenser modules to dispense powder into respective cartridges of a batch of cartridges in the cartridge tray, a powder transport system to deliver powder to the powder dispenser modules, a sensor module including sensor cells to sense respective fill states, such as the weights, of each of the cartridges in the batch of cartridges, and a control system to control the powder dispenser modules in response to the respective sensed fill states of each of the cartridges of the batch of cartridges.
摘要翻译： 提供粉末分配和感测装置和方法。 粉末分配和感测装置包括托盘支撑结构以容纳盒托盘保持盒，粉末分配器组件，包括粉末分配器模块，用于将粉末分配到盒托盘中的一批墨盒的相应墨盒中;粉末输送系统，用于输送粉末 传感器模块包括传感器单元，用于检测批次中的每个墨盒的各个填充状态，例如重量;以及控制系统，用于响应于相应感测到的粉末分配器模块来控制粉末分配器模块 填充一批墨盒的每个墨盒的状态。
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公开(公告)号：US20070131708A1
公开(公告)日：2007-06-14
申请号：US11602170
申请日：2006-11-20
申请人： Trent Poole , David Bonneau , Per Fog
发明人： Trent Poole , David Bonneau , Per Fog
摘要： Powder dispensing and sensing apparatus and methods are provided. The powder dispensing and sensing apparatus includes a tray support structure to receive a cartridge tray holding cartridges, a powder dispenser assembly including powder dispenser modules to dispense powder into respective cartridges of a batch of cartridges in the cartridge tray, a powder transport system to deliver powder to the powder dispenser modules, a sensor module including sensor cells to sense respective fill states, such as the weights, of each of the cartridges in the batch of cartridges, and a control system to control the powder dispenser modules in response to the respective sensed fill states of each of the cartridges of the batch of cartridges.
摘要翻译： 提供粉末分配和感测装置和方法。 粉末分配和感测装置包括托盘支撑结构以容纳盒托盘保持盒，粉末分配器组件，包括粉末分配器模块，用于将粉末分配到盒托盘中的一批墨盒的相应墨盒中;粉末输送系统，用于输送粉末 传感器模块包括传感器单元，用于检测批次中的每个墨盒的各个填充状态，例如重量;以及控制系统，用于响应于相应感测到的粉末分配器模块来控制粉末分配器模块 填充一批墨盒的每个墨盒的状态。
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公开(公告)号：US20070131707A1
公开(公告)日：2007-06-14
申请号：US11602063
申请日：2006-11-20
申请人： Trent Poole , David Bonneau , Per Fog
发明人： Trent Poole , David Bonneau , Per Fog
摘要： Powder dispensing and sensing apparatus and methods are provided. The powder dispensing and sensing apparatus includes a tray support structure to receive a cartridge tray holding cartridges, a powder dispenser assembly including powder dispenser modules to dispense powder into respective cartridges of a batch of cartridges in the cartridge tray, a powder transport system to deliver powder to the powder dispenser modules, a sensor module including sensor cells to sense respective fill states, such as the weights, of each of the cartridges in the batch of cartridges, and a control system to control the powder dispenser modules in response to the respective sensed fill states of each of the cartridges of the batch of cartridges.
摘要翻译： 提供粉末分配和感测装置和方法。 粉末分配和感测装置包括托盘支撑结构以容纳盒托盘保持盒，粉末分配器组件，包括粉末分配器模块，用于将粉末分配到盒托盘中的一批墨盒的相应墨盒中;粉末输送系统，用于输送粉末 传感器模块包括传感器单元，用于检测批次中的每个墨盒的各个填充状态，例如重量;以及控制系统，用于响应于相应感测到的粉末分配器模块来控制粉末分配器模块 填充一批墨盒的每个墨盒的状态。
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公开(公告)号：US20050155601A1
公开(公告)日：2005-07-21
申请号：US11037737
申请日：2005-01-18
申请人： Solomon Steiner , Craig Brown , Roderike Pohl , Trent Poole , Erik Steiner
发明人： Solomon Steiner , Craig Brown , Roderike Pohl , Trent Poole , Erik Steiner
CPC分类号： A61M11/00 , A61M15/0028 , A61M15/0048 , A61M15/0051 , A61M2202/064 , A61M2205/073 , A61M2205/8225
摘要： A drug delivery device that aerosolizes a dry powder formulation so that it forms a fine coating in the oral cavity and, more specifically, in the sublingual region of the oral cavity is described herein. In the preferred embodiment, the device contains five main parts: (i) a compressed gas canister, (ii) a dispenser body (also referred to herein as the main housing), (iii) a means for storing one or more doses of a drug formulation, (iv) a means for releasing a dose of the drug formulation such as a gas canister or spring piston and (v) a mouthpiece. Preferred configurations include circular, tubular, and rectangular. The means for storing the drug formulation may be configured to separately store one or more materials. In one embodiment, the means for storing the active agent is in the form of one or more drug discs, where the drug discs contain a plurality of blister packs, each storing one dose of the drug formulation. In another embodiment, the means for storing the active agent is a dosage cartridge containing a single dose of the drug formulation. In yet another embodiment, the drug formulation is stored on a ribbon containing a plurality of blister packs, each storing one dose of the drug formulation.
摘要翻译： 本文描述了使干燥粉末制剂气雾化以使其在口腔中，更具体地在口腔舌下区域中形成细小涂层的药物递送装置。 在优选实施例中，该装置包含五个主要部分：（i）压缩气体罐，（ii）分配器主体（在本文中也称为主壳体），（iii）用于存储一个或多个剂量的 药物制剂，（iv）用于释放剂量的药物制剂如气体罐或弹簧活塞的装置，（v）口器。 优选的构造包括圆形，管状和矩形。 用于储存药物制剂的方法可以被配置成分开存储一种或多种材料。 在一个实施方案中，用于储存活性剂的装置是一种或多种药物盘的形式，其中药物盘包含多个泡罩包装，每个存储一剂药物制剂。 在另一个实施方案中，用于储存活性剂的装置是含有单剂量药物制剂的剂量筒。 在另一个实施方案中，药物制剂储存在含有多个泡罩包装的条带上，每个存在一剂药物制剂。
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公开(公告)号：US20080047550A2
公开(公告)日：2008-02-28
申请号：US11037737
申请日：2005-01-18
申请人： Solomon Steiner , Craig Brown , Roderike Pohl , Trent Poole , Erik Steiner
发明人： Solomon Steiner , Craig Brown , Roderike Pohl , Trent Poole , Erik Steiner
CPC分类号： A61M11/00 , A61M15/0028 , A61M15/0048 , A61M15/0051 , A61M2202/064 , A61M2205/073 , A61M2205/8225
摘要： A drug delivery device that aerosolizes a dry powder formulation so that it forms a fine coating in the oral cavity and, more specifically in the sublingual region of the oral cavity is described herein. In the preferred embodiment, the device contains five main parts: (i) a compressed gas canister, (ii) a dispenser body (also referred to herein as the main housing ), (iii) a means for storing one or more doses of a drug formulation, (iv) a means for releasing a dose of the drug formulation such as a gas canister or spring piston and (v) a mouthpiece. Preferred configurations include circular, tubular, and rectangular. The means for storing the drug formulation may be configured to separately store one or more materials. In one embodiment, the means for storing the active agent is in the form of one or more drug discs, where the drug discs contain a plurality of blister packs, each storing one dose of the drug formulation. In another embodiment, the means for storing the active agent is a dosage cartridge containing a single dose of the drug formulation. In yet another embodiment, the drug formulation is stored on a ribbon containing a plurality of blister packs, each storing one dose of the drug formulation.
摘要翻译： 本文描述了使干燥粉末制剂雾化以使其在口腔中形成细小涂层并且更具体地在口腔的舌下区域中的药物递送装置。 在优选实施例中，该装置包含五个主要部分：（i）压缩气体罐，（ii）分配器主体（在本文中也称为主壳体），（iii）用于存储一个或多个剂量的 药物制剂，（iv）用于释放剂量的药物制剂如气体罐或弹簧活塞的装置，（v）口器。 优选的构造包括圆形，管状和矩形。 用于储存药物制剂的方法可以被配置成分开存储一种或多种材料。 在一个实施方案中，用于储存活性剂的装置是一种或多种药物盘的形式，其中药物盘包含多个泡罩包装，每个存储一剂药物制剂。 在另一个实施方案中，用于储存活性剂的装置是含有单剂量药物制剂的剂量筒。 在另一个实施方案中，药物制剂储存在含有多个泡罩包装的条带上，每个存在一剂药物制剂。
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公开(公告)号：US20080041372A1
公开(公告)日：2008-02-21
申请号：US11539082
申请日：2006-10-05
申请人： Trent Poole , Solomon Steiner
发明人： Trent Poole , Solomon Steiner
IPC分类号： A61M15/00
CPC分类号： A61M15/0093 , A61K9/14 , A61M15/0021 , A61M15/0025 , A61M15/0028 , A61M15/06 , A61M2202/064 , A61M2205/12 , A61M2206/16
摘要： An inhaler is instantly activated upon its removal from a cover or cover unit, and by rotating a cartridge component of the inhaler with respect to a mouthpiece portion, so as to create a flow pathway for ambient air and particles. The cartridge component includes a chamber, whose contents typically include dry powders or the like. Upon creation of the flow pathway, the contents of the chamber are instantly accessible for immediate inhalation by a user through the mouthpiece portion.
摘要翻译： 吸入器在从盖或盖单元移除时立即被激活，并且通过相对于接口部旋转吸入器的盒部件，以便为环境空气和颗粒产生流动通道。 墨盒组件包括一个室，其内容物通常包括干粉或类似物。 在产生流动路径时，腔室的内容物立即可以通过使用者通过接口部分立即吸入。
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公开(公告)号：US20050188988A1
公开(公告)日：2005-09-01
申请号：US11118853
申请日：2005-04-29
申请人： Trent Poole , Solomon Steiner
发明人： Trent Poole , Solomon Steiner
CPC分类号： A61M15/0093 , A61K9/14 , A61M15/0021 , A61M15/0025 , A61M15/0028 , A61M15/06 , A61M2202/064 , A61M2205/12 , A61M2206/16
摘要： An inhaler is instantly activated upon its removal from a cover or cover unit, and by rotating a cartridge component of the inhaler with respect to a mouthpiece portion, so as to create a flow pathway for ambient air and particles. The cartridge component includes a chamber, whose contents typically include dry powders or the like. Upon creation of the flow pathway, the contents of the chamber are instantly accessible for immediate inhalation by a user through the mouthpiece portion.
摘要翻译： 吸入器在从盖或盖单元移除时立即被激活，并且通过相对于接口部旋转吸入器的盒部件，以便为环境空气和颗粒产生流动通道。 墨盒组件包括一个室，其内容物通常包括干粉或类似物。 在产生流动路径时，腔室的内容物立即可以通过使用者通过接口部分立即吸入。
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公开(公告)号：US20120174923A1
公开(公告)日：2012-07-12
申请号：US13421529
申请日：2012-03-15
申请人： Solomon S. Steiner , Robert Feldstein , Per B. Fog , Trent Poole
发明人： Solomon S. Steiner , Robert Feldstein , Per B. Fog , Trent Poole
IPC分类号： A61M15/00
CPC分类号： A61M15/003 , A61M13/00 , A61M15/002 , A61M15/0021 , A61M15/0023 , A61M15/0025 , A61M15/0028 , A61M15/0043 , A61M16/0495 , A61M16/0825 , A61M2202/064 , A61M2205/43 , F16L37/252
摘要： Described is a dry powder inhaler comprising an intake section; a mixing section, and a mouthpiece.
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公开(公告)号：US08671937B2
公开(公告)日：2014-03-18
申请号：US13421529
申请日：2012-03-15
申请人： Solomon S. Steiner , Per B. Fog , Trent Poole , Robert Feldstein
发明人： Solomon S. Steiner , Per B. Fog , Trent Poole , Robert Feldstein
IPC分类号： A61M11/00
CPC分类号： A61M15/003 , A61M13/00 , A61M15/002 , A61M15/0021 , A61M15/0023 , A61M15/0025 , A61M15/0028 , A61M15/0043 , A61M16/0495 , A61M16/0825 , A61M2202/064 , A61M2205/43 , F16L37/252
摘要： Described is a dry powder inhaler comprising an intake section; a mixing section, and a mouthpiece.
摘要翻译： 描述了一种干粉吸入器，其包括进气段; 混合部分和喉舌。
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