公开(公告)号：US08564420B2

公开(公告)日：2013-10-22

申请号：US12935109

申请日：2009-03-20

申请人： Stefan Beyer ,  Klaus Pfitzner ,  Wolfgang Schatz ,  Andreas Thomas

发明人： Stefan Beyer ,  Klaus Pfitzner ,  Wolfgang Schatz ,  Andreas Thomas

IPC分类号： G05B11/01

CPC分类号： H01H71/08 ,  H01H50/021 ,  H01H2011/0037 ,  H01H2300/03 ,  H02J13/0003 ,  Y02B70/3241 ,  Y02B90/224 ,  Y02B90/228 ,  Y04S20/14 ,  Y04S20/18 ,  Y04S20/227

摘要： A control module with connection devices for connection to connection terminals of a load feeder is disclosed. The control module may include a device interface for at least one connection, the interface being independent of the bus system, with a shut-off element able to be connected to the at least one connection device and with the load feeder able to be shut off by way of the shut-off element independently of the bus system. The control module may be plugged into connection terminals of the load feeder.

摘要翻译： 公开了具有用于连接到负载馈送器的连接端子的连接装置的控制模块。 所述控制模块可以包括用于至少一个连接的设备接口，所述接口独立于所述总线系统，具有能够连接到所述至少一个连接装置并且所述负载馈线能够被切断的切断元件 通过独立于总线系统的切断元件。 控制模块可以插入负载馈线的连接端子。

公开(公告)号：US20110022772A1

公开(公告)日：2011-01-27

申请号：US12935109

申请日：2009-03-20

申请人： Stefan Beyer ,  Klaus Pfitzner ,  Wolfgang Schatz ,  Andreas Thomas

发明人： Stefan Beyer ,  Klaus Pfitzner ,  Wolfgang Schatz ,  Andreas Thomas

IPC分类号： G06F13/00

CPC分类号： H01H71/08 ,  H01H50/021 ,  H01H2011/0037 ,  H01H2300/03 ,  H02J13/0003 ,  Y02B70/3241 ,  Y02B90/224 ,  Y02B90/228 ,  Y04S20/14 ,  Y04S20/18 ,  Y04S20/227

摘要： A control module with connection devices for connection to connection terminals of a load feeder is disclosed, wherein the load feeder with the control module is connected to a bus system. In at least one embodiment, the control module includes a device interface for at least one connection, interface being independent of the bus system, with a shut-off element able to be connected to the at least one connection device and with the load feeder able to be shut off by way of the shut-off element independently of the bus system. At least one embodiment of the present invention further relates to a load feeder for turning a load on and off and/or for monitoring thereof, including first connection devices for connecting the load feeder to a bus system, second connection devices for connecting the load and a control module, wherein the control module is plugged into connection terminals of the load feeder for connecting to the load feeder and wherein the control module includes a device interface for at least one connection device, the interface being independent of the bus system, with a shut-off element able to be connected to the at least one connection device and with the load feeder able to be shut off by way of the shut-off element independently of the bus system.

摘要翻译： 公开了具有用于连接到负载馈送器的连接端子的连接装置的控制模块，其中具有控制模块的负载馈送器连接到总线系统。 在至少一个实施例中，控制模块包括用于至少一个连接的设备接口，独立于总线系统的接口，具有能够连接到至少一个连接装置的切断元件以及与负载馈送器 通过独立于总线系统的关闭元件来关闭。 本发明的至少一个实施例还涉及用于打开和关闭负载和/或用于监视负载的负载馈送器，包括用于将负载馈送器连接到总线系统的第一连接装置，用于连接负载的第二连接装置和 控制模块，其中所述控制模块插入到所述负载馈送器的连接端子以连接到所述负载馈送器，并且其中所述控制模块包括用于至少一个连接装置的装置接口，所述接口独立于所述总线系统， 切断元件能够连接到至少一个连接装置，并且能够通过独立于总线系统的切断元件关闭负载馈线。

公开(公告)号：US20060264812A1

公开(公告)日：2006-11-23

申请号：US11342946

申请日：2006-01-30

申请人： Rudolf Ehwald ,  Uwe Beyer ,  Andreas Thomas

发明人： Rudolf Ehwald ,  Uwe Beyer ,  Andreas Thomas

IPC分类号： A61M3/00

CPC分类号： A61B5/145 ,  A61B5/14528

摘要： A micro-dialysis probe extending longitudinally between a proximal probe opening and a distal probe tip and having a supply line and a drainage line for a drip-feed solution. A tube may be provided for supporting the drainage line. A dialysis section, wherein the flow channel for the drip-feed solution experiences an inversion, is formed generally between the supply line and the drainage line, in the vicinity of the distal probe tip. The supply line and the drainage line are respectively arranged substantially side by side and together form the probe shaft of the micro-dialysis probe.

摘要翻译： 微透析探针在近端探针开口和远端探针尖端之间纵向延伸，并具有用于滴注溶液的供应管线和排水管线。 可以设置用于支撑排水管的管。 一种透析部，其中，用于滴注溶液的流动通道经历反转，通常在远端探针末端附近形成在供应管线和排水管线之间。 供应线和排水管线分别大致并排设置，并一起形成微透析探针的探头轴。

公开(公告)号：US08235936B2

公开(公告)日：2012-08-07

申请号：US12951391

申请日：2010-11-22

申请人： Rudolf Ehwald ,  Uwe Beyer ,  Andreas Thomas

发明人： Rudolf Ehwald ,  Uwe Beyer ,  Andreas Thomas

IPC分类号： A61M3/00

CPC分类号： A61B5/145 ,  A61B5/14528

摘要： A micro-dialysis probe extending longitudinally between a proximal probe opening and a distal probe tip and having a supply line and a drainage line for a drip-feed solution. A tube may be provided for supporting the drainage line. A dialysis section, wherein the flow channel for the drip-feed solution experiences an inversion, is formed generally between the supply line and the drainage line, in the vicinity of the distal probe tip. The supply line and the drainage line are respectively arranged substantially side by side and together form the probe shaft of the micro-dialysis probe.

摘要翻译： 微透析探针在近端探针开口和远端探针尖端之间纵向延伸，并具有用于滴注溶液的供应管线和排水管线。 可以设置用于支撑排水管的管。 一种透析部，其中，用于滴注溶液的流动通道经历反转，通常在远端探针末端附近形成在供应管线和排水管线之间。 供应线和排水管线分别大致并排设置，并一起形成微透析探针的探头轴。

公开(公告)号：US07008398B2

公开(公告)日：2006-03-07

申请号：US10068670

申请日：2002-02-05

申请人： Rudolf Ehwald ,  Beyer Uwe ,  Andreas Thomas

发明人： Rudolf Ehwald ,  Beyer Uwe ,  Andreas Thomas

IPC分类号： A61M3/00

CPC分类号： A61B5/145 ,  A61B5/14528

摘要： A micro-dialysis probe extending longitudinally between a proximal probe opening and a distal probe tip and having a supply line and a drainage line for a drip-feed solution. A tube may be provided for supporting the drainage line. A dialysis section, wherein the flow channel for the drip-feed solution experiences an inversion, is formed generally between the supply line and the drainage line, in the vicinity of the distal probe tip. The supply line and the drainage line are arranged substantially side by side and together form the probe shaft of the micro-dialysis probe.

摘要翻译： 微透析探针在近端探针开口和远端探针尖端之间纵向延伸，并具有用于滴注溶液的供应管线和排水管线。 可以设置用于支撑排水管的管。 一种透析部，其中，用于滴注溶液的流动通道经历反转，通常在远端探针末端附近形成在供应管线和排水管线之间。 供给管线和排水管线大致并排布置，并一起形成微透析探针的探针轴。

公开(公告)号：US06477891B2

公开(公告)日：2002-11-12

申请号：US09897357

申请日：2001-07-02

申请人： Rudolf Ehwald ,  Karl-Ernst Ehwald ,  Andreas Thomas ,  Uwe Beyer

发明人： Rudolf Ehwald ,  Karl-Ernst Ehwald ,  Andreas Thomas ,  Uwe Beyer

IPC分类号： G01N3000

CPC分类号： A61B5/14532 ,  G01N11/08 ,  G01N2001/4016

摘要： The invention concerns a process for affinity viscosimetry and a viscosimetric affinity sensor on the basis of sensitive liquids with analyte-dependent viscosity which are localized within a perfusable dialysis chamber and contain colloidal constituents which are cross-linked by affinity bonds. The viscosimetric affinity sensor according to this invention is characterized by the spatial or temporal separation of analyte diffusion from the measurement of the flow resistance for such sensitive liquid flowing through a capillary, needle-like body or other liquid conductor, which integrated combination of a dialysis chamber with viscosimeter enables a researcher to make measurements under lab conditions that provide spatial separation of the dialysis process from the rheological analysis, as done under test conditions where the maximum shear rate of sensitive liquid in the viscosity sensor is at least twice that shear rate of sensitive liquid experienced in the dialysis chamber. An important advantage of the invention consists in small volume-displacement and negligible structural change within the matrix or organ of living tissue to be investigated.

摘要翻译： 本发明涉及一种基于具有分析物依赖性粘度的敏感液体的亲和​​力粘度测定法和粘度测定亲和力传感器，其位于可灌注透析室内并含有通过亲和键交联的胶体成分。 根据本发明的粘度亲和力传感器的特征在于分析物扩散与流过毛细管，针状体或其它液体导体的敏感液体的流动阻力的测量的空间或时间分离，其将透析 具有粘度计的腔室使得研究人员能够在实验室条件下进行测量，从而提供透析过程与流变学分析的空间分离，如在粘度传感器中敏感液体的最大剪切速率至少为剪切速率的两倍 在透析室中经历的敏感液体。 本发明的一个重要优点在于待研究的活体组织的基质或器官内的小体积位移和结构变化可以忽略不计。

公开(公告)号：US07918818B2

公开(公告)日：2011-04-05

申请号：US11342946

申请日：2006-01-30

申请人： Rudolf Ehwald ,  Uwe Beyer ,  Andreas Thomas

发明人： Rudolf Ehwald ,  Uwe Beyer ,  Andreas Thomas

IPC分类号： A61M3/00

CPC分类号： A61B5/145 ,  A61B5/14528

摘要： A micro-dialysis probe extending longitudinally between a proximal probe opening and a distal probe tip and having a supply line and a drainage line for a drip-feed solution. A tube may be provided for supporting the drainage line. A dialysis section, wherein the flow channel for the drip-feed solution experiences an inversion, is formed generally between the supply line and the drainage line, in the vicinity of the distal probe tip. The supply line and the drainage line are respectively arranged substantially side by side and together form the probe shaft of the micro-dialysis probe.

摘要翻译： 微透析探针在近端探针开口和远端探针尖端之间纵向延伸，并具有用于滴注溶液的供应管线和排水管线。 可以设置用于支撑排水管的管。 一种透析部，其中，用于滴注溶液的流动通道经历反转，通常在远端探针末端附近形成在供应管线和排水管线之间。 供应线和排水管线分别大致并排设置，并一起形成微透析探针的探头轴。

公开(公告)号：US20110066103A1

公开(公告)日：2011-03-17

申请号：US12951391

申请日：2010-11-22

申请人： Rudolf Ehwald ,  Beyer Uwe ,  Andreas Thomas

发明人： Rudolf Ehwald ,  Beyer Uwe ,  Andreas Thomas

IPC分类号： A61M1/00

CPC分类号： A61B5/145 ,  A61B5/14528

摘要： A micro-dialysis probe extending longitudinally between a proximal probe opening and a distal probe tip and having a supply line and a drainage line for a drip-feed solution. A tube may be provided for supporting the drainage line. A dialysis section, wherein the flow channel for the drip-feed solution experiences an inversion, is formed generally between the supply line and the drainage line, in the vicinity of the distal probe tip. The supply line and the drainage line are respectively arranged substantially side by side and together form the probe shaft of the micro-dialysis probe.

摘要翻译： 微透析探针在近端探针开口和远端探针尖端之间纵向延伸，并具有用于滴注溶液的供应管线和排水管线。 可以设置用于支撑排水管的管。 一种透析部，其中，用于滴注溶液的流动通道经历反转，通常在远端探针末端附近形成在供应管线和排水管线之间。 供应线和排水管线分别大致并排设置，并一起形成微透析探针的探头轴。

公开(公告)号：US20100106000A1

公开(公告)日：2010-04-29

申请号：US12604685

申请日：2009-10-23

申请人： Andreas Thomas

发明人： Andreas Thomas

IPC分类号： A61B5/145 ,  A61M5/14

CPC分类号： G16H40/20 ,  A61B5/14532 ,  A61B5/7275 ,  A61B5/743 ,  G06F19/3456

摘要： A method of evaluating glycemic control of a patient includes providing a pentagon having five axes radiating from a center of the pentagon. A first pentagon area formed by a first point, a second point, a third point, a fourth point, and a fifth point plotted on the five axes, respectively, is determined. A second pentagon area formed by a sixth point, a seventh point, an eighth point, a ninth point, and a tenth point plotted on the five axes, respectively, is determined. A glycemic control parameter is determined based on the first pentagon area and the second pentagon area.

摘要翻译： 一种评估患者血糖控制的方法包括提供五边形，五边形从五边形的中心辐射。 确定由分别绘制在五个轴上的第一点，第二点，第三点，第四点和第五点形成的第一五边形区域。 确定由分别绘制在五个轴上的第六点，第七点，第八点，第九点和第十点形成的第二五边形区域。 基于第一五边形区域和第二五边形区域来确定血糖控制参数。

公开(公告)号：US06267002B1

公开(公告)日：2001-07-31

申请号：US09416839

申请日：1999-10-12

申请人： Rudolf Ehwald ,  Karl-Ernst Ehwald ,  Andreas Thomas ,  Uwe Beyer

发明人： Rudolf Ehwald ,  Karl-Ernst Ehwald ,  Andreas Thomas ,  Uwe Beyer

IPC分类号： G01N3000

CPC分类号： A61B5/14532 ,  G01N11/08 ,  G01N2001/4016

摘要： The invention concerns a process for affinity viscosimetry and a viscosimetric affinity sensor on the basis of sensitive liquids with analyte-dependent viscosity which are localized within a perfusable dialysis chamber and contain colloidal constituents which are cross-linked by affinity bonds. The viscosimetric affinity sensor according to this invention is characterized by the spatial or temporal separation of analyte diffusion from the measurement of the flow resistance for such sensitive liquid flowing through a capillary, needle-like body or other liquid conductor, which integrated combination of a dialysis chamber with viscosimeter enables a researcher to make measurements under lab conditions that provide spatial separation of the dialysis process from the rheological analysis, as done under test conditions where the maximum shear rate of sensitive liquid in the viscosity sensor is at least twice that shear rate of sensitive liquid experienced in the dialysis chamber. An important advantage of the invention consists in small volume-displacement and negligible structural change within the matrix or organ of living tissue to be investigated.

摘要翻译： 本发明涉及一种基于具有分析物依赖性粘度的敏感液体的亲和​​力粘度测定法和粘度测定亲和力传感器，其位于可灌注透析室内并含有通过亲和键交联的胶体成分。 根据本发明的粘度亲和力传感器的特征在于分析物扩散与流过毛细管，针状体或其它液体导体的敏感液体的流动阻力的测量的空间或时间分离，其将透析 具有粘度计的腔室使得研究人员能够在实验室条件下进行测量，从而提供透析过程与流变学分析的空间分离，如在粘度传感器中敏感液体的最大剪切速率至少为剪切速率的两倍 在透析室中经历的敏感液体。 本发明的一个重要优点在于待研究的活体组织的基质或器官内的小体积位移和结构变化可以忽略不计。