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公开(公告)号:US07915318B2
公开(公告)日:2011-03-29
申请号:US12207055
申请日:2008-09-09
申请人: Su Lu , Liangliang Qiang , Yanrong Zhu , Zhida Pan
发明人: Su Lu , Liangliang Qiang , Yanrong Zhu , Zhida Pan
CPC分类号: C08F290/00 , B01J20/28042 , B01J20/286 , B01J20/288 , C08F255/00 , C08F255/08 , C08F277/00 , C08F290/06 , C08F291/00 , C08G61/08 , C08L51/003 , C08L51/06 , G01N2030/528 , C08L2666/02
摘要: A water soluble ROMP catalyst, which has high catalytic efficiency for ring opening metathesis is use in the preparation of polymeric blends for use in monolithic columns. In one embodiments a method for making a polymeric blend is discolosed comprising reaction of a water-soluble ROMP catalyst with a norbornene-substituted cycloolefin polymer or a polynorbornene polymer precursor, and wherein the contacting occurs in an aqueous or polar solvent in the presence of a solid support. In another embodiment a monolithic bed is disclosed comprising the water-soluble ROMP catalyst immobilized on a surface of a solid support. Also disclosed is a monolithic bed comprising: a polymer blend, the polymer blend produced from contacting a water soluble ROMP catalyst with a norbornene-substituted cycloolefin polymer or a polynorbornene polymer precursor; and wherein the contacting occurs in an aqueous or polar solvent in the presence of a solid support.
摘要翻译: 对于开环复分解具有高催化效率的水溶性ROMP催化剂用于制备用于整体柱的聚合物共混物。 在一个实施方案中,制造聚合物共混物的方法被解开,包括水溶性ROMP催化剂与降冰片烯取代的环烯烃聚合物或聚降冰片烯聚合物前体的反应,并且其中所述接触在水溶液或极性溶剂中,在 坚实的支持。 在另一个实施方案中,公开了一种整体床,其包含固定在固体载体表面上的水溶性ROMP催化剂。 还公开了一种整体床,包括:聚合物共混物,通过使水溶性ROMP催化剂与降冰片烯取代的环烯烃聚合物或聚降冰片烯聚合物前体接触而制备的聚合物共混物; 并且其中所述接触在固体载体存在下在水性或极性溶剂中进行。
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公开(公告)号:US20100063200A1
公开(公告)日:2010-03-11
申请号:US12207055
申请日:2008-09-09
申请人: Su Lu , Liangliang Qiang , Yanrong Zhu , Zhida Pan
发明人: Su Lu , Liangliang Qiang , Yanrong Zhu , Zhida Pan
CPC分类号: C08F290/00 , B01J20/28042 , B01J20/286 , B01J20/288 , C08F255/00 , C08F255/08 , C08F277/00 , C08F290/06 , C08F291/00 , C08G61/08 , C08L51/003 , C08L51/06 , G01N2030/528 , C08L2666/02
摘要: A water soluble ROMP catalyst, which has high catalytic efficiency for ring opening metathesis is use in the preparation of polymeric blends for use in monolithic columns. In one embodiments a method for making a polymeric blend is discolosed comprising reaction of a water-soluble ROMP catalyst with a norbornene-substituted cycloolefin polymer or a polynorbornene polymer precursor, and wherein the contacting occurs in an aqueous or polar solvent in the presence of a solid support. In another embodiment a monolithic bed is disclosed comprising the water-soluble ROMP catalyst immobilized on a surface of a solid support. Also disclosed is a monolithic bed comprising: a polymer blend, the polymer blend produced from contacting a water soluble ROMP catalyst with a norbornene-substituted cycloolefin polymer or a polynorbornene polymer precursor; and wherein the contacting occurs in an aqueous or polar solvent in the presence of a solid support.
摘要翻译: 对于开环复分解具有高催化效率的水溶性ROMP催化剂用于制备用于整体柱的聚合物共混物。 在一个实施方案中,制造聚合物共混物的方法被解开,包括水溶性ROMP催化剂与降冰片烯取代的环烯烃聚合物或聚降冰片烯聚合物前体的反应,并且其中所述接触在水溶液或极性溶剂中,在 坚实的支持。 在另一个实施方案中,公开了一种整体床,其包含固定在固体载体表面上的水溶性ROMP催化剂。 还公开了一种整体床,包括:聚合物共混物,通过使水溶性ROMP催化剂与降冰片烯取代的环烯烃聚合物或聚降冰片烯聚合物前体接触而制备的聚合物共混物; 并且其中所述接触在固体载体存在下在水性或极性溶剂中进行。
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公开(公告)号:US20100015633A1
公开(公告)日:2010-01-21
申请号:US12175673
申请日:2008-07-18
申请人: Su Lu , Li Zhu , Zhida Pan , Liangliang Qiang , John Yupeng Gui
发明人: Su Lu , Li Zhu , Zhida Pan , Liangliang Qiang , John Yupeng Gui
IPC分类号: G01N33/53 , G01N33/566
CPC分类号: G01N33/585 , C12Q1/6816 , G01N33/587 , C12Q2563/137 , C12Q2527/119
摘要: A method includes binding a probe to an analyte present in a sample, wherein the probe comprises a binder bonded to a metal particle that is capable of releasing metal ions when contacted with a reagent solution. The method includes contacting the metal particle with the reagent solution to release the metal ions, and observing an optical signal from the released metal ions to determine a presence or amount of the analyte in the sample. An associated kit is also provided.
摘要翻译: 一种方法包括将探针结合到样品中存在的分析物,其中探针包含与金属颗粒结合的粘合剂,当与试剂溶液接触时能够释放金属离子。 该方法包括使金属颗粒与试剂溶液接触以释放金属离子,并观察来自释放的金属离子的光信号以确定样品中分析物的存在或量。 还提供了相关的套件。
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公开(公告)号:US20120122733A1
公开(公告)日:2012-05-17
申请号:US11680646
申请日:2007-03-01
申请人: Zhida Pan , Su Lu , Liangliang Qiang , John Yupeng Gui , John Richard Nelson , Bahram Moasser , Anup Sood , Gregory Andrew Grossmann , Wei Cai , Zhixin Zheng
发明人: Zhida Pan , Su Lu , Liangliang Qiang , John Yupeng Gui , John Richard Nelson , Bahram Moasser , Anup Sood , Gregory Andrew Grossmann , Wei Cai , Zhixin Zheng
摘要: The composition includes a first probe and a first initiator bonded to the first probe. The composition further includes a second probe and a second initiator bonded to the second probe. The first probe and the second probe are capable of binding to a single analyte. An associated kit, device, and method are provided.
摘要翻译: 组合物包括第一探针和结合到第一探针的第一引发剂。 组合物还包括第二探针和结合到第二探针的第二引发剂。 第一个探针和第二个探针能够结合单个分析物。 提供相关的套件,设备和方法。
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公开(公告)号:US20080306230A1
公开(公告)日:2008-12-11
申请号:US11759333
申请日:2007-06-07
申请人: Zhida Pan , Su Lu , Liangliang Qiang
发明人: Zhida Pan , Su Lu , Liangliang Qiang
IPC分类号: B01J31/22 , C07D207/00 , C07D327/00 , C07F3/08 , C08F4/72 , C08F4/80
CPC分类号: C07F15/0046 , B01J31/2265 , B01J2231/543 , B01J2531/821 , C07D207/00 , C07D327/00 , C08G61/08
摘要: A composition includes a Group (VIII) transition metal, an anionic ligand bonded to the metal, a neutral electron donor ligand bonded to the metal, and an alkylidene group bonded to the metal. The alkylidene group includes a cycloaliphatic radical substituted with an ionic group. An associated method is also provided.
摘要翻译: 组合物包括第(VIII)族过渡金属,与金属键合的阴离子配体,与金属键合的中性电子给体配体和与金属键合的亚烷基。 亚烷基包括被离子基团取代的脂环族基团。 还提供了相关联的方法。
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公开(公告)号:US08778846B2
公开(公告)日:2014-07-15
申请号:US11680652
申请日:2007-03-01
申请人: John Richard Nelson , Bahram Moasser , Anup Sood , Gregory Andrew Grossmann , Su Lu , Zhida Pan , Liangliang Qiang , John Yupeng Gui , Wei Cai , Zhixin Zheng
发明人: John Richard Nelson , Bahram Moasser , Anup Sood , Gregory Andrew Grossmann , Su Lu , Zhida Pan , Liangliang Qiang , John Yupeng Gui , Wei Cai , Zhixin Zheng
IPC分类号: C40B40/04 , G01N33/53 , G01N33/566
CPC分类号: G01N33/5308
摘要: A composition includes a first probe, a first initiator component bonded to the first probe, a second probe, and a second initiator component bonded to the second probe. The first probe and the second probe are capable of binding to a single analyte, and the first initiator component and the second initiator component are capable of forming an initiator when present in proximity to each other and when the first probe and the second probe are bonded to the analyte. An associated kit, device, and method are provided.
摘要翻译: 组合物包括第一探针,结合到第一探针的第一引发剂组分,第二探针和结合到第二探针的第二引发剂组分。 第一探针和第二探针能够结合单个分析物,并且第一引发剂组分和第二引发剂组分能够在彼此接近存在时形成引发剂,并且当第一探针和第二探针结合时 分析物。 提供相关的套件,设备和方法。
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公开(公告)号:US20120122735A1
公开(公告)日:2012-05-17
申请号:US11680652
申请日:2007-03-01
申请人: John Richard Nelson , Bahram Moasser , Anup Sood , Gregory Andrew Grossmann , Su Lu , Zhida Pan , Liangliang Qiang , John Yupeng Gui , Wei Cai , Zhixin Zheng
发明人: John Richard Nelson , Bahram Moasser , Anup Sood , Gregory Andrew Grossmann , Su Lu , Zhida Pan , Liangliang Qiang , John Yupeng Gui , Wei Cai , Zhixin Zheng
CPC分类号: G01N33/5308
摘要: A composition includes a first probe, a first initiator component bonded to the first probe, a second probe, and a second initiator component bonded to the second probe. The first probe and the second probe are capable of binding to a single analyte, and the first initiator component and the second initiator component are capable of forming an initiator when present in proximity to each other and when the first probe and the second probe are bonded to the analyte. An associated kit, device, and method are provided.
摘要翻译: 组合物包括第一探针,结合到第一探针的第一引发剂组分,第二探针和结合到第二探针的第二引发剂组分。 第一探针和第二探针能够结合单个分析物,并且第一引发剂组分和第二引发剂组分能够在彼此接近存在时形成引发剂,并且当第一探针和第二探针结合时 分析物。 提供相关的套件,设备和方法。
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公开(公告)号:US08765643B2
公开(公告)日:2014-07-01
申请号:US11680646
申请日:2007-03-01
申请人: Zhida Pan , Su Lu , Liangliang Qiang , John Yupeng Gui , John Richard Nelson , Bahram Moasser , Anup Sood , Gregory Andrew Grossmann , Wei Cai , Zhixin Zheng
发明人: Zhida Pan , Su Lu , Liangliang Qiang , John Yupeng Gui , John Richard Nelson , Bahram Moasser , Anup Sood , Gregory Andrew Grossmann , Wei Cai , Zhixin Zheng
IPC分类号: C40B40/04 , G01N33/53 , G01N33/566
摘要: The composition includes a first probe and a first initiator bonded to the first probe. The composition further includes a second probe and a second initiator bonded to the second probe. The first probe and the second probe are capable of binding to a single analyte. An associated kit, device, and method are provided.
摘要翻译: 组合物包括第一探针和结合到第一探针的第一引发剂。 组合物还包括第二探针和结合到第二探针的第二引发剂。 第一个探针和第二个探针能够结合单个分析物。 提供相关的套件,设备和方法。
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公开(公告)号:US08383337B2
公开(公告)日:2013-02-26
申请号:US12175673
申请日:2008-07-18
申请人: Su Lu , Li Zhu , Zhida Pan , Liangliang Qiang , John Yupeng Gui
发明人: Su Lu , Li Zhu , Zhida Pan , Liangliang Qiang , John Yupeng Gui
CPC分类号: G01N33/585 , C12Q1/6816 , G01N33/587 , C12Q2563/137 , C12Q2527/119
摘要: A method includes binding a probe to an analyte present in a sample, wherein the probe comprises a binder bonded to a metal particle that is capable of releasing metal ions when contacted with a reagent solution. The method includes contacting the metal particle with the reagent solution to release the metal ions, and observing an optical signal from the released metal ions to determine a presence or amount of the analyte in the sample. An associated kit is also provided.
摘要翻译: 一种方法包括将探针结合到样品中存在的分析物,其中探针包含与金属颗粒结合的粘合剂,当与试剂溶液接触时能够释放金属离子。 该方法包括使金属颗粒与试剂溶液接触以释放金属离子,并观察来自释放的金属离子的光信号以确定样品中分析物的存在或量。 还提供了相关的套件。
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10.
公开(公告)号:US20110315563A1
公开(公告)日:2011-12-29
申请号:US13164656
申请日:2011-06-20
IPC分类号: G01N27/30 , G01N27/327
CPC分类号: A61B5/14865 , A61B5/14532 , A61B5/1473 , A61B5/1495 , A61B2560/0223 , A61B2562/028 , A61B2562/0285 , A61B2562/04 , A61B2562/125
摘要: Disclosed herein is a sensor comprising a conduit; the conduit comprising an organic polymer; a working electrode; the working electrode being etched and decorated with a nanostructured material; a reference electrode; and a counter electrode; the working electrode, the reference electrode and the counter electrode being disposed in the conduit; the working electrode, the reference electrode and the counter electrode being separated from each other by an electrically insulating material; and wherein a cross-sectional area of the conduit that comprises a section of the working electrode, a section of the reference electrode and a section of the counter electrode is exposed to detect analytes.
摘要翻译: 本文公开了一种传感器,其包括导管; 导管包含有机聚合物; 工作电极 工作电极用纳米结构材料进行蚀刻和装饰; 参考电极; 和对电极; 工作电极,参比电极和对电极设置在导管中; 工作电极,参考电极和对电极通过电绝缘材料彼此分离; 并且其中包括所述工作电极的一部分,参考电极的一部分和所述对电极的一部分的所述导管的横截面面积被暴露以检测分析物。
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