Aqueous ROMP-based monolith materials and methods for making
    1.
    发明授权
    Aqueous ROMP-based monolith materials and methods for making 有权
    基于水性ROMP的整料材料及其制备方法

    公开(公告)号:US07915318B2

    公开(公告)日:2011-03-29

    申请号:US12207055

    申请日:2008-09-09

    IPC分类号: C08F2/44 B01J20/26 C08F4/80

    摘要: A water soluble ROMP catalyst, which has high catalytic efficiency for ring opening metathesis is use in the preparation of polymeric blends for use in monolithic columns. In one embodiments a method for making a polymeric blend is discolosed comprising reaction of a water-soluble ROMP catalyst with a norbornene-substituted cycloolefin polymer or a polynorbornene polymer precursor, and wherein the contacting occurs in an aqueous or polar solvent in the presence of a solid support. In another embodiment a monolithic bed is disclosed comprising the water-soluble ROMP catalyst immobilized on a surface of a solid support. Also disclosed is a monolithic bed comprising: a polymer blend, the polymer blend produced from contacting a water soluble ROMP catalyst with a norbornene-substituted cycloolefin polymer or a polynorbornene polymer precursor; and wherein the contacting occurs in an aqueous or polar solvent in the presence of a solid support.

    摘要翻译: 对于开环复分解具有高催化效率的水溶性ROMP催化剂用于制备用于整体柱的聚合物共混物。 在一个实施方案中,制造聚合物共混物的方法被解开,包括水溶性ROMP催化剂与降冰片烯取代的环烯烃聚合物或聚降冰片烯聚合物前体的反应,并且其中所述接触在水溶液或极性溶剂中,在 坚实的支持。 在另一个实施方案中,公开了一种整体床,其包含固定在固体载体表面上的水溶性ROMP催化剂。 还公开了一种整体床,包括:聚合物共混物,通过使水溶性ROMP催化剂与降冰片烯取代的环烯烃聚合物或聚降冰片烯聚合物前体接触而制备的聚合物共混物; 并且其中所述接触在固体载体存在下在水性或极性溶剂中进行。

    AQUEOUS ROMP-BASED MONOLITH MATERIALS AND METHODS FOR MAKING
    2.
    发明申请
    AQUEOUS ROMP-BASED MONOLITH MATERIALS AND METHODS FOR MAKING 有权
    基于ROMP的单组分材料及其制备方法

    公开(公告)号:US20100063200A1

    公开(公告)日:2010-03-11

    申请号:US12207055

    申请日:2008-09-09

    IPC分类号: C08L55/00 B01J31/12

    摘要: A water soluble ROMP catalyst, which has high catalytic efficiency for ring opening metathesis is use in the preparation of polymeric blends for use in monolithic columns. In one embodiments a method for making a polymeric blend is discolosed comprising reaction of a water-soluble ROMP catalyst with a norbornene-substituted cycloolefin polymer or a polynorbornene polymer precursor, and wherein the contacting occurs in an aqueous or polar solvent in the presence of a solid support. In another embodiment a monolithic bed is disclosed comprising the water-soluble ROMP catalyst immobilized on a surface of a solid support. Also disclosed is a monolithic bed comprising: a polymer blend, the polymer blend produced from contacting a water soluble ROMP catalyst with a norbornene-substituted cycloolefin polymer or a polynorbornene polymer precursor; and wherein the contacting occurs in an aqueous or polar solvent in the presence of a solid support.

    摘要翻译: 对于开环复分解具有高催化效率的水溶性ROMP催化剂用于制备用于整体柱的聚合物共混物。 在一个实施方案中,制造聚合物共混物的方法被解开,包括水溶性ROMP催化剂与降冰片烯取代的环烯烃聚合物或聚降冰片烯聚合物前体的反应,并且其中所述接触在水溶液或极性溶剂中,在 坚实的支持。 在另一个实施方案中,公开了一种整体床,其包含固定在固体载体表面上的水溶性ROMP催化剂。 还公开了一种整体床,包括:聚合物共混物,通过使水溶性ROMP催化剂与降冰片烯取代的环烯烃聚合物或聚降冰片烯聚合物前体接触而制备的聚合物共混物; 并且其中所述接触在固体载体存在下在水性或极性溶剂中进行。

    METHODS AND KIT FOR ANALYTE DETECTION
    3.
    发明申请
    METHODS AND KIT FOR ANALYTE DETECTION 有权
    分析检测方法和试剂盒

    公开(公告)号:US20100015633A1

    公开(公告)日:2010-01-21

    申请号:US12175673

    申请日:2008-07-18

    IPC分类号: G01N33/53 G01N33/566

    摘要: A method includes binding a probe to an analyte present in a sample, wherein the probe comprises a binder bonded to a metal particle that is capable of releasing metal ions when contacted with a reagent solution. The method includes contacting the metal particle with the reagent solution to release the metal ions, and observing an optical signal from the released metal ions to determine a presence or amount of the analyte in the sample. An associated kit is also provided.

    摘要翻译: 一种方法包括将探针结合到样品中存在的分析物,其中探针包含与金属颗粒结合的粘合剂,当与试剂溶液接触时能够释放金属离子。 该方法包括使金属颗粒与试剂溶液接触以释放金属离子,并观察来自释放的金属离子的光信号以确定样品中分析物的存在或量。 还提供了相关的套件。

    Methods using metal oxide particles for analyte detection
    9.
    发明授权
    Methods using metal oxide particles for analyte detection 有权
    使用金属氧化物颗粒进行分析物检测的方法

    公开(公告)号:US08383337B2

    公开(公告)日:2013-02-26

    申请号:US12175673

    申请日:2008-07-18

    IPC分类号: C12Q1/68 C07H21/04 C07K5/00

    摘要: A method includes binding a probe to an analyte present in a sample, wherein the probe comprises a binder bonded to a metal particle that is capable of releasing metal ions when contacted with a reagent solution. The method includes contacting the metal particle with the reagent solution to release the metal ions, and observing an optical signal from the released metal ions to determine a presence or amount of the analyte in the sample. An associated kit is also provided.

    摘要翻译: 一种方法包括将探针结合到样品中存在的分析物,其中探针包含与金属颗粒结合的粘合剂,当与试剂溶液接触时能够释放金属离子。 该方法包括使金属颗粒与试剂溶液接触以释放金属离子,并观察来自释放的金属离子的光信号以确定样品中分析物的存在或量。 还提供了相关的套件。

    SENSORS FOR ANALYTE DETECTION AND METHODS OF MANUFACTURE THEREOF
    10.
    发明申请
    SENSORS FOR ANALYTE DETECTION AND METHODS OF MANUFACTURE THEREOF 有权
    用于分析物检测的传感器及其制造方法

    公开(公告)号:US20110315563A1

    公开(公告)日:2011-12-29

    申请号:US13164656

    申请日:2011-06-20

    IPC分类号: G01N27/30 G01N27/327

    摘要: Disclosed herein is a sensor comprising a conduit; the conduit comprising an organic polymer; a working electrode; the working electrode being etched and decorated with a nanostructured material; a reference electrode; and a counter electrode; the working electrode, the reference electrode and the counter electrode being disposed in the conduit; the working electrode, the reference electrode and the counter electrode being separated from each other by an electrically insulating material; and wherein a cross-sectional area of the conduit that comprises a section of the working electrode, a section of the reference electrode and a section of the counter electrode is exposed to detect analytes.

    摘要翻译: 本文公开了一种传感器,其包括导管; 导管包含有机聚合物; 工作电极 工作电极用纳米结构材料进行蚀刻和装饰; 参考电极; 和对电极; 工作电极,参比电极和对电极设置在导管中; 工作电极,参考电极和对电极通过电绝缘材料彼此分离; 并且其中包括所述工作电极的一部分,参考电极的一部分和所述对电极的一部分的所述导管的横截面面积被暴露以检测分析物。