公开(公告)号：US20130136904A1

公开(公告)日：2013-05-30

申请号：US13307141

申请日：2011-11-30

申请人： Sujith Nair ,  Howell B. Eleazer ,  Purushothama K. Ullal ,  Padmakumar Puthillath ,  Thomas W. Newbill ,  Kevin Hazen ,  Gary K. Greene

发明人： Sujith Nair ,  Howell B. Eleazer ,  Purushothama K. Ullal ,  Padmakumar Puthillath ,  Thomas W. Newbill ,  Kevin Hazen ,  Gary K. Greene

IPC分类号： B32B25/08 ,  B32B38/00 ,  B32B25/10 ,  B32B5/26 ,  B32B3/10

CPC分类号： B32B5/024 ,  B29D30/0016 ,  B29D2030/0038 ,  B32B5/26 ,  B32B5/28 ,  B32B27/12 ,  B32B27/32 ,  B32B2250/20 ,  B32B2250/40 ,  B32B2255/02 ,  B32B2255/26 ,  B32B2260/023 ,  B32B2260/046 ,  B32B2262/0253 ,  B32B2307/514 ,  Y10T428/2481 ,  Y10T442/3041

摘要： A winder liner for unvulcanized rubber material comprising a first woven layer, a second woven layer, and a polymer layer. The first and second woven layers each contain a plurality of warp tape elements in a warp direction interwoven with a plurality of weft tape elements in a weft direction and a plurality of interstices between the warp and weft tape elements. The polymer layer is disposed on the inner surfaces of the first woven layer and the second woven layer and in the interstices of the first woven layer and the second woven layer. The polymer layer contains a first polymer comprising a co-polymer having at least 50% α-olefin units and is characterized by a number-average molecular weight of about 7,000 to 500,000 g/mol, and a viscosity of between about 2,500 and 150,000 cP measured at 170° C.

摘要翻译： 一种用于未硫化橡胶材料的卷绕衬套，包括第一编织层，第二编织层和聚合物层。 第一和第二编织层各自包含多个经向方向的经向带元件，其沿纬纱方向与多个纬带元件交织，并且在经线和纬带元件之间具有多个间隙。 聚合物层设置在第一编织层和第二编织层的内表面以及第一编织层和第二编织层的间隙中。 聚合物层含有包含具有至少50％的α-烯烃单元的共聚物的第一聚合物，其特征在于数均分子量为约7,000至500,000g / mol，粘度为约2,500至150,000cP 在170℃测量

公开(公告)号：US20230240347A1

公开(公告)日：2023-08-03

申请号：US17590670

申请日：2022-02-01

申请人： Kevin Hazen ,  Mason Cave ,  Michael Roth

发明人： Kevin Hazen ,  Mason Cave ,  Michael Roth

IPC分类号： A23L29/00 ,  A23L2/54 ,  A23L2/68 ,  A23L5/40 ,  A23L2/395 ,  A23P10/28

CPC分类号： A23L29/035 ,  A23L2/54 ,  A23L2/68 ,  A23L5/40 ,  A23L2/395 ,  A23P10/28

摘要： The invention comprises an apparatus, comprising: (1) a dissolvable tablet, comprising: a support matrix, the support matrix comprising at least two percent by mass a gassing agent, the gassing agent comprising at least one of: a carbonic acid, H2CO3; a bicarbonate, HCO3; a bicarbonate salt; a carbonate, CO32−; and a carbonate salt; and (2) at least one milligram of tetrahydrocannabinol, where the dissolvable tablet optionally includes an acid and a buffer at least partially separating the gassing agent and the acid, where the tetrahydrocannabinol is blended into the support matrix of the dissolvable tablet prior to formation of the dissolvable tablet and/or is infused into a pre-made tablet comprising the support matrix.

公开(公告)号：US11678819B2

公开(公告)日：2023-06-20

申请号：US16667020

申请日：2019-10-29

申请人： Roxanne Abul-Haj ,  Kevin Hazen ,  Christopher Slawinski ,  Alan Abul-Haj

发明人： Roxanne Abul-Haj ,  Kevin Hazen ,  Christopher Slawinski ,  Alan Abul-Haj

IPC分类号： A61B5/145 ,  G01N21/359 ,  A61B5/1455 ,  A61B5/00 ,  G01N21/47 ,  G01N21/17 ,  G01N21/49

CPC分类号： A61B5/14532 ,  A61B5/0051 ,  A61B5/1455 ,  A61B5/6841 ,  G01N21/1717 ,  G01N21/359 ,  G01N21/474 ,  G01N21/49 ,  G01N2021/1729

摘要： The invention comprises an applied force-optic analyzer used to determine a sample constituent concentration, a physical measure of the sample, and/or a state of the sample. The analyzer comprises: an electro-mechanical transducer affixed to skin of a subject; a controller, the controller providing a voltage waveform to the electro-mechanical transducer driving displacement of the skin and inducing a pressure wave into the skin; and a spectrometer interfaced to a sample site of the skin, the spectrometer comprising a set of sources and a set of detectors, where the controller is configured to collect signal from the set of detectors as a function of timing of the voltage waveform and apply a calibration model to the signal to determine the analyte concentration.

公开(公告)号：US20220129718A1

公开(公告)日：2022-04-28

申请号：US17550866

申请日：2021-12-14

申请人： Michael Roth ,  Kevin Hazen ,  Mason Cave

发明人： Michael Roth ,  Kevin Hazen ,  Mason Cave

IPC分类号： G06K19/06 ,  G06K19/077 ,  G06Q30/06 ,  G06Q10/08 ,  G08B13/24 ,  A23L2/38 ,  A23L33/105 ,  G09F3/00

摘要： The invention comprises a method and/or an apparatus for operating a Cannabis facility generating a tetrahydrocannabinol (THC) containing product, comprising the step of labeling the THC containing product with a matrix bar code/quick response (QR) code, the cannabis containing product comprising at least two milligrams of a tetrahydrocannabinol substance, the QR code linking to product information associated with the THC containing product, the product information comprising at least one of a location, date of harvest, strain, and/or type of a plant containing a tetrahydrocannabinol substance in the THC containing product; an extraction method; a date and/or a location of manufacture of the THC product; a related laboratory report; and/or a link to a related web page.

公开(公告)号：US20200163596A1

公开(公告)日：2020-05-28

申请号：US16691615

申请日：2019-11-22

申请人： Alodeep Sanyal ,  Benjamin Mbouombouo ,  Roxanne Abul-Haj ,  Alan Abul-Haj ,  Christopher Slawinski ,  Kevin Hazen

发明人： Alodeep Sanyal ,  Benjamin Mbouombouo ,  Roxanne Abul-Haj ,  Alan Abul-Haj ,  Christopher Slawinski ,  Kevin Hazen

IPC分类号： A61B5/145 ,  A61B5/00

摘要： The invention comprises a method for noninvasively determining a sample property, comprising controlling photon generation from a source and analyzing signal from a set of detectors; irradiating an illumination zone of skin with the photons; and detecting diffusely reflected photons from the skin, the set of detectors respectively optically coupled to a set of detection zones of the skin positioned along a spiral path between a first and second radial distance from the illumination zone, where a first detection zone of a first detector of the set of detectors extends radially outward from the illumination zone to at least an inward radial distance, from the illumination zone, of a second detection zone of a second detector of the set of detectors, where at least one detection zone of the set of detection zones has a central radial distance from the illumination zone between the first and second radial distances.

公开(公告)号：US20150011849A1

公开(公告)日：2015-01-08

申请号：US14493266

申请日：2014-09-22

申请人： Timothy Ruchti ,  Alan Abul-Haj ,  Kevin Hazen

发明人： Timothy Ruchti ,  Alan Abul-Haj ,  Kevin Hazen

IPC分类号： A61B5/1455 ,  A61B5/00 ,  A61B5/145

CPC分类号： A61B5/1455 ,  A61B5/14532 ,  A61B5/6801 ,  A61B2562/04 ,  A61B2562/046

摘要： A noninvasive analyzer apparatus and method of use thereof is described using a plurality of sample illumination zones optically coupled to at least two optically stacked two-dimensional optical filter arrays. Sectioned pixels and/or zones of a detector array are optionally filtered for different light throughput and/or are passed through various pathlengths using the stacked two-dimensional optical filter arrays. Resulting pathlength resolved/wavelength controlled groups of spectra are subsequently analyzed to determine an analyte property.

摘要翻译： 使用光学耦合到至少两个光学堆叠的二维光学滤波器阵列的多个采样照明区域来描述非侵入性分析仪装置及其使用方法。 可选地，为了不同的光通过量滤波检测器阵列的截面像素和/或区域，和/或使用堆叠的二维光学滤波器阵列通过各种路径长度。 随后分析得到的光程长度解析/波长控制的光谱组，以确定分析物质。

公开(公告)号：US20070293743A1

公开(公告)日：2007-12-20

申请号：US11848139

申请日：2007-08-30

申请人： Stephen Monfre ,  George Acosta ,  Thomas Blank ,  Kevin Hazen

发明人： Stephen Monfre ,  George Acosta ,  Thomas Blank ,  Kevin Hazen

IPC分类号： A61B5/00

CPC分类号： A61B5/6841 ,  A61B5/14532 ,  A61B5/1455 ,  G01N21/359 ,  G01N21/474

摘要： A placement guide apparatus with an improved hydration inducing plug used in coupling a noninvasive analyzer to a sampling site to determine analyte in the human body is disclosed. The hydration inducing plug includes at least one fluoropolymer that may be used as a coupling agent. The guide apparatus may further include an automated or semi-automated coupling fluid delivery system. Use of either of these couplers mitigates issues associated with related technology and enhances noninvasive analyte measurements, such as a near-IR diffuse reflectance based noninvasive glucose concentration analyzer.

摘要翻译： 公开了一种具有改进的水合诱导塞的放置引导装置，其用于将非侵入性分析器耦合到取样部位以确定人体中的分析物。 水合诱导塞包括至少一种可用作偶联剂的含氟聚合物。 引导装置还可以包括自动化或半自动化耦合流体输送系统。 使用这些耦合剂中的任一种可减轻与相关技术相关的问题，并增强非侵入性分析物测量，例如基于近红外漫反射的非侵入性葡萄糖浓度分析仪。

公开(公告)号：US20060195023A1

公开(公告)日：2006-08-31

申请号：US11326958

申请日：2006-01-05

申请人： George Acosta ,  James Henderson ,  N. Abul Haj ,  Timothy Ruchti ,  Stephen Monfre ,  Thomas Blank ,  Kevin Hazen

发明人： George Acosta ,  James Henderson ,  N. Abul Haj ,  Timothy Ruchti ,  Stephen Monfre ,  Thomas Blank ,  Kevin Hazen

IPC分类号： A61B5/00

CPC分类号： A61B5/1455 ,  A61B5/0075 ,  A61B5/14532 ,  A61B5/1495 ,  A61B5/6833 ,  A61B5/7203 ,  A61B5/7225 ,  A61B5/726 ,  A61B2560/0223 ,  A61B2560/0233 ,  A61B2560/0252 ,  A61B2560/0412 ,  A61B2560/0443 ,  A61B2560/0456 ,  A61B2562/0242 ,  A61B2562/146 ,  A61B2562/227 ,  A61B2562/228 ,  G01N21/359 ,  G01N21/49

摘要： The invention involves the monitoring of a biological parameter through a compact analyzer. The preferred apparatus is a spectrometer based system that is attached continuously or semi-continuously to a human subject and collects spectral measurements that are used to determine a biological parameter in the sampled tissue. The preferred target analyte is glucose. The preferred analyzer is a near-IR based glucose analyzer for determining the glucose concentration in the body.

公开(公告)号：US20060116562A1

公开(公告)日：2006-06-01

申请号：US11335067

申请日：2006-01-18

申请人： George Acosta ,  James Henderson ,  N. Abul Haj ,  Timothy Ruchti ,  Stephen Monfre ,  Thomas Blank ,  Kevin Hazen

发明人： George Acosta ,  James Henderson ,  N. Abul Haj ,  Timothy Ruchti ,  Stephen Monfre ,  Thomas Blank ,  Kevin Hazen

IPC分类号： A61B5/00

CPC分类号： A61B5/1455 ,  A61B5/0075 ,  A61B5/14532 ,  A61B5/1495 ,  A61B5/6833 ,  A61B5/7203 ,  A61B5/7225 ,  A61B5/726 ,  A61B2560/0223 ,  A61B2560/0233 ,  A61B2560/0252 ,  A61B2560/0412 ,  A61B2560/0443 ,  A61B2560/0456 ,  A61B2562/0242 ,  A61B2562/146 ,  A61B2562/227 ,  A61B2562/228 ,  G01N21/359 ,  G01N21/49

摘要： The invention involves the monitoring of a biological parameter through a compact analyzer. The preferred apparatus is a spectrometer based system that is attached continuously or semi-continuously to a human subject and collects spectral measurements that are used to determine a biological parameter in the sampled tissue. The preferred target analyte is glucose. The preferred analyzer is a near-IR based glucose analyzer for determining the glucose concentration in the body.

摘要翻译： 本发明涉及通过紧凑型分析仪监测生物参数。 优选的装置是基于光谱仪的系统，其连续地或半连续地连接到人类受试者并收集用于确定采样组织中的生物学参数的光谱测量。 优选的目标分析物是葡萄糖。 优选的分析仪是用于测定体内葡萄糖浓度的基于近红外的葡萄糖分析仪。

公开(公告)号：US20050267342A1

公开(公告)日：2005-12-01

申请号：US11117104

申请日：2005-04-27

申请人： Thomas Blank ,  George Acosta ,  Timothy Ruchti ,  Mutua Mattu ,  Alexander Lorenz ,  Kevin Hazen ,  James Henderson

发明人： Thomas Blank ,  George Acosta ,  Timothy Ruchti ,  Mutua Mattu ,  Alexander Lorenz ,  Kevin Hazen ,  James Henderson

IPC分类号： A61B5/00 ,  G01N21/35

CPC分类号： A61B5/1455 ,  A61B5/14532 ,  A61B5/1495 ,  A61B5/4869 ,  A61B2560/0223 ,  A61B2560/0233 ,  A61B2562/0242 ,  G01N21/359

摘要： A method and apparatus are provided for noninvasive sampling. More particularly, the method and apparatus relate to control of motion of an optical sample probe interface relative to a tissue sample site. A dynamic probe interface, is used to collect spectra of a targeted sample, control positioning of the sample probe relative to the tissue sample in terms of at least one of x-, y-, and z-axes, and/or control of sample tissue displacement to minimize spectral variations resulting from the sampling process and increase analyte property estimation precision and accuracy.

摘要翻译： 提供了一种用于无创采样的方法和装置。 更具体地，该方法和装置涉及光学样本探针界面相对于组织样本位点的运动的控制。 使用动态探针接口来收集目标样品的光谱，根据x-，y-和z-轴中的至少一个来控​​制样品探针相对于组织样品的定位和/或样品的控制 组织位移以最小化由采样过程导致的频谱变化，并增加分析物质的估计精度和精度。