公开(公告)号：US20120101571A1

公开(公告)日：2012-04-26

申请号：US13130180

申请日：2009-11-20

申请人： Suku Thambar ,  Martin Christopher Cook ,  Stefan Schreck ,  Stayajit Rohan Jayasinghe

发明人： Suku Thambar ,  Martin Christopher Cook ,  Stefan Schreck ,  Stayajit Rohan Jayasinghe

IPC分类号： A61F2/24

CPC分类号： A61B17/0057 ,  A61B2017/00575 ,  A61B2017/0061 ,  A61F2/2418 ,  A61F2/2436 ,  A61F2/2457 ,  A61F2002/8486 ,  A61F2220/0008 ,  A61F2220/0016 ,  A61F2230/0054 ,  A61F2230/0078 ,  A61F2230/008 ,  A61F2250/006

摘要： A heart valve prosthesis (100) comprises a housing component (110) and a valve component (130). The housing component (110) comprises a housing body (111) having a housing passage (112) extending therethrough. The housing body (111) is configured to be located in, or adjacent to and communicating with, a native valve orifice (16) of a heart (10) and to engage structure of the heart (10) to fix the housing body (111) in relation to the valve orifice (161). The housing component (111) is collapsible for delivery via catheter (2). The valve component (130) comprises a valve body (131) having a valve passage (132) extending therethrough. The valve body (131) is configured to be fixed within the housing passage (112) with the valve passage (132) extending along the housing passage (112). One or more flexible valve elements (131) is/are secured to the valve body and extend across the valve passage (132) for blocking blood flow in a first direction through the valve passage (132) whilst allowing blood flow in the opposing direction. The valve component (130) is collapsible for delivery via catheter (2) separate to the housing component (110). An associated method of replacing a failed or failing heart valve utilising the heart valve prosthesis (100) is also disclosed.

摘要翻译： 心脏瓣膜假体（100）包括壳体部件（110）和阀部件（130）。 壳体部件（110）包括具有延伸穿过其的壳体通道（112）的壳体（111）。 壳体（111）构造成位于心脏（10）的天然瓣膜（16）中或邻近并连通，并与心脏（10）的结构接合以固定壳体（111） ）相对于阀孔（161）。 壳体部件（111）可折叠以便经由导管（2）输送。 阀部件（130）包括具有延伸穿过其中的阀通道（132）的阀体（131）。 阀体（131）构造成固定在壳体通道（112）内，阀通道（132）沿壳体通道（112）延伸。 一个或多个柔性阀元件（131）被固定到阀体并延伸穿过阀通道（132），用于阻止通过阀通道（132）的第一方向的血流，同时允许血液沿相反方向流动。 阀部件（130）可折叠以便通过分离到壳体部件（110）的导管（2）输送。 还公开了利用心脏瓣膜假体（100）代替故障或故障心脏瓣膜的相关方法。

公开(公告)号：US10166014B2

公开(公告)日：2019-01-01

申请号：US13130180

申请日：2009-11-20

申请人： Suku Thambar ,  Martin Christopher Cook ,  Stefan Schreck ,  Stayajit Rohan Jayasinghe

发明人： Suku Thambar ,  Martin Christopher Cook ,  Stefan Schreck ,  Stayajit Rohan Jayasinghe

IPC分类号： A61F2/24 ,  A61B17/00 ,  A61F2/848

摘要： A heart valve prosthesis (100) comprises a housing component (110) and a valve component (130). The housing component (110) comprises a housing body (111) having a housing passage (112) extending therethrough. The housing body (111) is configured to be located in, or adjacent to and communicating with, a native valve orifice (16) of a heart (10) and to engage structure of the heart (10) to fix the housing body (111) in relation to the valve orifice (161). The housing component (111) is collapsible for delivery via catheter (2). The valve component (130) comprises a valve body (131) having a valve passage (132) extending therethrough. The valve body (131) is configured to be fixed within the housing passage (112) with the valve passage (132) extending along the housing passage (112). One or more flexible valve elements (131) is/are secured to the valve body and extend across the valve passage (132) for blocking blood flow in a first direction through the valve passage (132) whilst allowing blood flow in the opposing direction. The valve component (130) is collapsible for delivery via catheter (2) separate to the housing component (110). An associated method of replacing a failed or failing heart valve utilising the heart valve prosthesis (100) is also disclosed.

公开(公告)号：US08821564B2

公开(公告)日：2014-09-02

申请号：US13397952

申请日：2012-02-16

申请人： Stefan Schreck ,  Daniel Hawkins

发明人： Stefan Schreck ,  Daniel Hawkins

IPC分类号： A61F2/06

CPC分类号： A61F2/07 ,  A61F2/2412 ,  A61F2/856 ,  A61F2/89 ,  A61F2/90 ,  A61F2002/065 ,  A61F2002/067 ,  A61F2002/075 ,  A61F2002/077 ,  A61F2220/005 ,  A61F2220/0075 ,  A61F2250/0024

摘要： Some embodiments are directed to a stent graft comprising a first stent graft having a first and a second stent and a first and a second inner graft supported by the first stent, and an outer graft. The second inner graft can be spaced apart from the first inner graft so that a portion of the first stent is not covered by either the first inner graft or the second inner graft. A first and second portion of the outer graft can be attached to the first stent, the outer graft being unsupported by the stent between the first and second portions so as to form a fillable space between the outer graft, the first inner graft, and the second inner graft. Some embodiments further comprise a second stent graft deployable within the inside of the first stent graft to sealingly cover the uncovered portion of the first stent.

摘要翻译： 一些实施例涉及包括具有第一和第二支架的第一支架移植物和由第一支架支撑的第一和第二内部移植物以及外部移植物的支架移植物。 第二内部移植物可以与第一内部移植物间隔开，使得第一支架的一部分不被第一内部移植物或第二内部移植物覆盖。 外部移植物的第一和第二部分可以附接到第一支架，外部移植物在第一和第二部分之间不被支架支撑，以便在外部移植物，第一内部移植物和第二部分之间形成可填充的空间 第二内移植物。 一些实施例还包括可展开在第一支架移植物内部的第二支架移植物，以密封地覆盖第一支架的未覆盖部分。

公开(公告)号：US20120226341A1

公开(公告)日：2012-09-06

申请号：US13408952

申请日：2012-02-29

申请人： Stefan Schreck ,  Elbert Tzeng ,  Todd Abraham ,  Jonathan Phan ,  Joshua Benjamin ,  Jacqueline Macias ,  Kevin Chu ,  William L. Gould

发明人： Stefan Schreck ,  Elbert Tzeng ,  Todd Abraham ,  Jonathan Phan ,  Joshua Benjamin ,  Jacqueline Macias ,  Kevin Chu ,  William L. Gould

IPC分类号： A61F2/82

CPC分类号： A61F2/966 ,  A61F2/07 ,  A61F2/90 ,  A61F2/954 ,  A61F2002/9517 ,  A61F2002/9665 ,  A61M25/0097 ,  A61M25/0662 ,  A61M2025/09125

摘要： A modular catheter system including a sheath projecting distally from a delivery catheter having a main body module An inner core module carrying a stent thereon, the inner core being axially movable through the main body of the delivery catheter and the delivery catheter sheath, a handle member supported by the main body of the delivery catheter, the handle member being selectively axially engageable with the inner core such that the handle member and the inner core move together in an axial direction when the handle member is engaged with the inner core; and an adjustment member supported by the main body, the adjustment member being configured such that rotation of the adjustment member causes the adjustment member to move axially along the main body by either axially sliding the handle member relative to the main body or by rotating the adjustment member.

摘要翻译： 一种模块化导管系统，包括从具有主体模块的输送导管向远侧突出的鞘。所述内芯模块在其上承载支架，所述内芯可轴向移动通过所述输送导管的主体和所述输送导管护套， 所述手柄构件由所述输送导管的主体支撑，所述手柄构件与所述内芯选择性地可轴向接合，使得当所述手柄构件与所述内芯接合时，所述手柄构件和所述内芯在轴向方向一起移动; 以及由所述主体支撑的调节构件，所述调节构件被构造成使得所述调节构件的旋转使得所述调节构件通过相对于所述主体轴向滑动所述把手构件或通过使所述调节部的旋转而沿着所述主体轴向移动 会员。

公开(公告)号：US08118856B2

公开(公告)日：2012-02-21

申请号：US12844266

申请日：2010-07-27

申请人： Stefan Schreck ,  Daniel Hawkins

发明人： Stefan Schreck ,  Daniel Hawkins

IPC分类号： A61F2/06

CPC分类号： A61F2/07 ,  A61F2/2412 ,  A61F2/856 ,  A61F2/89 ,  A61F2/90 ,  A61F2002/065 ,  A61F2002/067 ,  A61F2002/075 ,  A61F2002/077 ,  A61F2220/005 ,  A61F2220/0075 ,  A61F2250/0024

摘要： Some embodiments are directed to a stent graft comprising a first stent graft having a first stent, a first inner graft supported by the first stent, a second inner graft supported by the first stent, and an outer graft. The second inner graft can be spaced apart from the first inner graft so that a portion of the first stent is not covered by the first inner graft or the second inner graft. A first and second portion of the outer graft can be attached to the first stent, the outer graft being unsupported by the stent between the first and second portions so as to form a fillable space between the outer graft, the first inner graft, and the second inner graft. Some embodiments further comprise a second stent graft deployable within the inside of the first stent graft to sealingly cover the uncovered portion of the first stent.

摘要翻译： 一些实施例涉及包括具有第一支架的第一支架移植物，由第一支架支撑的第一内移植物，由第一支架支撑的第二内移植物和外移植物的支架移植物。 第二内部移植物可以与第一内部移植物间隔开，使得第一支架的一部分不被第一内部移植物或第二内部移植物覆盖。 外部移植物的第一和第二部分可以附接到第一支架，外部移植物在第一和第二部分之间不被支架支撑，以便在外部移植物，第一内部移植物和第二部分之间形成可填充的空间 第二内移植物。 一些实施例还包括可展开在第一支架移植物内部的第二支架移植物，以密封地覆盖第一支架的未覆盖部分。

公开(公告)号：US20110218617A1

公开(公告)日：2011-09-08

申请号：US13039157

申请日：2011-03-02

申请人： Jonathon Nguyen ,  Jacqueline Macias ,  Elbert Tzeng ,  Stefan Schreck

发明人： Jonathon Nguyen ,  Jacqueline Macias ,  Elbert Tzeng ,  Stefan Schreck

IPC分类号： A61F2/82

CPC分类号： A61F2/82

摘要： Some embodiments of an endoluminal prosthesis comprise a graft having a first end and a second end, a first stent positioned at a first end of the graft, the first stent comprising a plurality of proximal apices and a plurality of distal apices, a second stent positioned axially adjacent to the first stent comprising a plurality of proximal apices positioned at a first end of the second stent. In some embodiments, the first stent can be partially covered by the graft such that the proximal apices of the first stent are not covered by the graft. The distal apices of the first stent can be positioned approximately on a first or a second plane offset from the first plane. The second stent can be positioned relative to the first stent such that the plurality of proximal apices of the second stent are spaced apart from the plurality of distal apices of the first stent. Further, one or more of the proximal apices of the second stent can be positioned approximately on a third or a fourth plane. The distal apices of the first stent can be circumferentially offset from the proximal apices of the second stent.

摘要翻译： 腔内假体的一些实施例包括具有第一端和第二端的移植物，位于移植物的第一端的第一支架，第一支架包括多个近侧顶点和多个远侧顶点，第二支架定位 轴向邻近第一支架，其包括位于第二支架第一端的多个近端顶点。 在一些实施例中，第一支架可以被移植物部分地覆盖，使得第一支架的近端顶端不被移植物覆盖。 第一支架的远端顶点可以大致位于从第一平面偏移的第一或第二平面上。 第二支架可以相对于第一支架定位，使得第二支架的多个近侧顶点与第一支架的多个远端顶点间隔开。 此外，第二支架的近侧顶点中的一个或多个可以大致位于第三或第四平面上。 第一支架的远侧顶点可以从第二支架的近端顶端周向偏移。

公开(公告)号：US20110015718A1

公开(公告)日：2011-01-20

申请号：US12837398

申请日：2010-07-15

申请人： Stefan Schreck

发明人： Stefan Schreck

IPC分类号： A61F2/84

CPC分类号： A61F2/962 ,  A61F2/07 ,  A61F2/90 ,  A61F2/954 ,  A61F2/966 ,  A61F2002/061 ,  A61F2002/065 ,  A61F2002/075 ,  A61F2002/825 ,  A61F2002/826

摘要： Some embodiments are directed to a deployment system for deploying a stent graft within a passageway, comprising a delivery catheter having an outer sheath, a proximal end, and a distal end, a stent having a first end and a second end, a graft having a first end and a second end, and at least one connecting element extending from the second end of the stent to the first end of the graft so as to connect the stent to the graft. In some embodiments, the stent can be supported within the outer sheath at a first axial position in a collapsed state, and the graft can be supported within the outer sheath at a second axial position different than the first axial position in a collapsed state, such that the stent does not overlap or substantially overlap the graft in the collapsed state within the deployment system.

摘要翻译： 一些实施例涉及用于在通道内展开支架移植物的展开系统，包括具有外护套，近端和远端的输送导管，具有第一端和第二端的支架，移植物具有 第一端和第二端，以及从支架的第二端延伸到移植物的第一端的至少一个连接元件，以将支架连接到移植物。 在一些实施例中，支架可以在处于折叠状态的第一轴向位置处支撑在外护套内，并且移植物可以在处于折叠状态的第二轴向位置处不同于第一轴向位置的情况下被支撑在外护套内， 支架在展开系统内处于折叠状态下不与移植物重叠或基本重叠。

公开(公告)号：US20090228100A1

公开(公告)日：2009-09-10

申请号：US12471203

申请日：2009-05-22

申请人： Jan Otto Solem ,  Per Ola Kimblad ,  Stevan Nielsen ,  Ib Joergenson ,  Bodo Quint ,  Gerd Seibold ,  Randolf Von Oepen ,  Suk-Woo Ha ,  Karl-Ludwig Eckert ,  Stefan Schreck ,  Sepehr Fariabi ,  Tommy Conzelmann

发明人： Jan Otto Solem ,  Per Ola Kimblad ,  Stevan Nielsen ,  Ib Joergenson ,  Bodo Quint ,  Gerd Seibold ,  Randolf Von Oepen ,  Suk-Woo Ha ,  Karl-Ludwig Eckert ,  Stefan Schreck ,  Sepehr Fariabi ,  Tommy Conzelmann

IPC分类号： A61F2/24

CPC分类号： A61F2/2451

摘要： An elongate body including a proximal and distal anchor, and a bridge between the proximal and distal anchors. The bridge has an elongated state, having first axial length, and a shortened state, having a second axial length, wherein the second axial length is shorter than the first axial length. A resorbable thread may be woven into the bridge to hold the bridge in the elongated state and to delay the transfer of the bridge to the shortened state. In an additional embodiment, there may be one or more central anchors between the proximal and distal anchors with a bridge connecting adjacent anchors.

摘要翻译： 包括近端和远端锚固件的细长主体以及近端和远端锚固件之间的桥梁。 桥具有第一轴向长度的细长状态和具有第二轴向长度的缩短状态，其中第二轴向长度短于第一轴向长度。 可再吸收的线可以编织到桥中以将桥梁保持在细长状态，并且将桥的传递延迟到缩短状态。 在另外的实施例中，在近端和远端锚固件之间可以有一个或多个中心锚固件，其具有连接相邻锚固件的桥。

公开(公告)号：US20060030866A1

公开(公告)日：2006-02-09

申请号：US11247947

申请日：2005-10-11

申请人： Stefan Schreck

发明人： Stefan Schreck

IPC分类号： A61B17/10

CPC分类号： A61B17/0469 ,  A61B17/00234 ,  A61B2017/00783 ,  A61B2017/0472 ,  A61F2/2409

摘要： A heart valve and tissue repair device for independently, selectively and sequentially grasping heart valve leaflets and independently, selectively and sequentially applying one or more fasteners thereto is disclosed. The device includes a leaflet engaging tip having one or more graspers capable of individually and sequentially grasping leaflets, and one or more deployable fasteners capable of fastening the leaflets. An actuation system for the device individually and selectively controls the graspers and deploys the one or more fasteners. Vacuum pressure from an external vacuum source can be used to grasp the leaflets via a selector system that controls the actuation system so as to individually and sequentially apply vacuum force to the graspers.

公开(公告)号：US20050267493A1

公开(公告)日：2005-12-01

申请号：US11186119

申请日：2005-07-20

申请人： Stefan Schreck ,  William Allen ,  Scott Reed ,  Alan Bachman ,  Robert Steckel ,  Frederick Karl ,  Leland Adams ,  Robert Chapolini

发明人： Stefan Schreck ,  William Allen ,  Scott Reed ,  Alan Bachman ,  Robert Steckel ,  Frederick Karl ,  Leland Adams ,  Robert Chapolini

IPC分类号： A61B17/00 ,  A61B17/04 ,  A61B17/06 ,  A61B17/064 ,  A61B17/068 ,  A61B17/122 ,  A61B17/30 ,  A61B17/10

CPC分类号： A61B17/068 ,  A61B17/0469 ,  A61B17/0482 ,  A61B17/064 ,  A61B17/122 ,  A61B17/1227 ,  A61B2017/00243 ,  A61B2017/00783 ,  A61B2017/06057 ,  A61B2017/0641 ,  A61B2017/306

摘要： The present system is directed to a method and system to stabilize and repair tissue. At least two opposing devices may be used to stabilize and repair the tissue, with the two devices cooperatively engaging the tissue interposed therebetween. Stabilization may be accomplished by opposing force, vacuum force, or mechanical devices disposed at the distal portion of one or both devices. After the tissue has been stabilized, fasteners may be deployed into the tissue. Fasteners include sutures, clips, and staples. Also disclosed is a minimally invasive method of accessing tissue located within a body and conducting a repair of the area using the system disclosed herein.

摘要翻译： 本系统针对稳定和修复组织的方法和系统。 可以使用至少两个相对的装置来稳定和修复组织，其中两个装置协同地将组织插入其间。 稳定化可以通过设置在一个或两个装置的远端部分的相反的力，真空力或机械装置来实现。 在组织稳定之后，紧固件可以部署到组织中。 紧固件包括缝线，夹子和钉。 还公开了一种使用本文公开的系统访问身体内的组织并进行该区域的修复的微创方法。