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    ANTI-CANCER PHARMACEUTICAL COMPOSITION
    1.
    发明申请
    ANTI-CANCER PHARMACEUTICAL COMPOSITION 审中-公开
    抗癌药物组合物

    公开(公告)号：US20140235559A1

    公开(公告)日：2014-08-21

    申请号：US14004746

    申请日：2011-06-15

    申请人： Sung-Wuk Kim ,  Sung-Soo Jun ,  Chang-Hee Min ,  Ja-Seong Koo ,  Jin-Wook Kim ,  Yong-Eun Kim ,  Sang-Ouk Sun

    发明人： Sung-Wuk Kim ,  Sung-Soo Jun ,  Chang-Hee Min ,  Ja-Seong Koo ,  Jin-Wook Kim ,  Yong-Eun Kim ,  Sang-Ouk Sun

    IPC分类号： A61K31/7004 ,  A61K9/48 ,  A61K9/28 ,  A61K31/155 ,  A61K31/506

    CPC分类号： A61K31/7004 ,  A61K9/2031 ,  A61K9/2054 ,  A61K9/209 ,  A61K9/2866 ,  A61K9/4866 ,  A61K9/5084 ,  A61K31/155 ,  A61K31/506 ,  A61K45/06 ,  A61K2300/00

    摘要： Disclosed is an anticancer pharmaceutical composition comprising phenformin or a pharmaceutically acceptable salt thereof, and 2-deoxy-D-glucose as active ingredients. These ingredients act in synergy with each other, thus exhibiting more potent inhibitory activity against the growth of cancer cells, compared to individual ingredients. Also, the synergistic anticancer activity allows the individual drugs to be used in lower amounts, which leads to a reduction in the occurrence of adverse effects. In addition, the time-lag release or administration of the ingredients decreases blood lactic acid levels to significantly mitigate the adverse effect of lactic acidosis, as well as exerting high anticancer effects. Particularly, the pharmaceutical composition can be formulated to dosage forms effective for therapy, increasing the drug compliance of the subject.

    摘要翻译： 公开了包含苯乙双胍或其药学上可接受的盐和2-脱氧-D-葡萄糖作为活性成分的抗癌药物组合物。 与各成分相比，这些成分彼此协同作用，因此对癌细胞的生长具有更强的抑制活性。 此外，协同抗癌活性允许以较低的量使用单独的药物，这导致副作用的发生减少。 此外，成分的时间延迟释放或给药降低了血液乳酸水平，以显着减轻乳酸性酸中毒的不利影响，并发挥高抗癌作用。 特别地，药物组合物可以配制成对治疗有效的剂型，增加受试者的药物依从性。

    FLOW CONTROL VALVE FOR CONSTRUCTION MACHINERY
    4.
    发明申请
    FLOW CONTROL VALVE FOR CONSTRUCTION MACHINERY 有权
    用于建筑机械的流量控制阀

    公开(公告)号：US20150159678A1

    公开(公告)日：2015-06-11

    申请号：US14411717

    申请日：2012-07-19

    申请人： Jin-Wook Kim

    发明人： Jin-Wook Kim

    IPC分类号： F15B11/024 ,  F15B11/04 ,  F15B13/02

    CPC分类号： F15B11/024 ,  E02F9/2267 ,  F15B11/0406 ,  F15B11/0426 ,  F15B13/021 ,  F15B13/0403 ,  F15B2211/205 ,  F15B2211/20576 ,  F15B2211/30565 ,  F15B2211/3133 ,  F15B2211/31582 ,  F15B2211/355 ,  F16K11/07 ,  Y10T137/87193

    摘要： Disclosed is a flow control valve for construction machinery, the flow control valve being adapted to reduce pressure loss due to flow on return to a hydraulic tank during the boom-down operation of a large-scale excavator. The flow control valve for construction machinery according to the present invention comprises: first and second boom spools which are respectively coupled to first and second boom valve blocks, and which regulate working fluid that is respectively supplied from first and second hydraulic pumps to a boom cylinder during direction reversal; a boom-up flow-adjusting means which, in direction reversal of the first and second boom spools for boom-up drive, supplies working fluid from the first and second hydraulic pumps into a large chamber of the boom cylinder via the first and second boom spools respectively, and causes part of the flow of working fluid from the second hydraulic pump to pass via the second boom spool so as to be combined with working fluid being supplied from the first hydraulic pump to the large chamber of the boom cylinder due to direction reversal of the first boom spool; and a boom-down flow-adjusting means which, in direction reversal of the first and second boom spools for boom-down drive, causes part of the flow of working fluid coming back from the large chamber of the boom cylinder to return to the hydraulic tank via the first and second boom spools respectively, and causes part of the flow of working fluid coming back from the large chamber of the boom cylinder to combine as respective regenerative flows for working fluid on the small chamber side of the boom cylinder.

    摘要翻译： 公开了一种用于工程机械的流量控制阀，该流量控制阀适于在大型挖掘机的动臂下降操作期间减少由于返回到液压油箱时的流量而导致的压力损失。 根据本发明的用于工程机械的流量控制阀包括：第一和第二悬臂线轴，其分别联接到第一和第二悬臂阀块，并且将分别从第一和第二液压泵供应的工作流体调节到动臂缸 在方向反转时 一个动臂上升流量调节装置，其在第一和第二悬臂起动驱动器的方向反转中，将来自第一和第二液压泵的工作流体经由第一和第二起重臂提供到动臂缸的大腔室中 并且使得来自第二液压泵的工作流体的一部分流动经由第二起重臂卷轴通过，以便与从第一液压泵供应到工作液体的工作流体相结合，由于方向 反转第一个吊杆; 以及动臂下降流量调节装置，其在第一和第二动臂用于动臂下降驱动的方向反转中使得从动臂缸的大腔返回的工作流体的一部分流动返回至液压 并且使得从动臂缸的大室返回的工作流体的一部分流动被组合为在动臂缸的小室侧上的工作流体的各自的再生流。

    Micro audio
    7.
    外观设计
    Micro audio 有权
    微音频

    公开(公告)号：USD626565S1

    公开(公告)日：2010-11-02

    申请号：US29348536

    申请日：2010-01-15

    申请人： Jin-Wook Kim

    设计人： Jin-Wook Kim

    HYDRAULIC PRESSURE-REGULATING VALVE FOR CONSTRUCTION EQUIPMENT
    10.
    发明申请
    HYDRAULIC PRESSURE-REGULATING VALVE FOR CONSTRUCTION EQUIPMENT 有权
    用于建筑设备的液压调压阀

    公开(公告)号：US20130032233A1

    公开(公告)日：2013-02-07

    申请号：US13641318

    申请日：2010-05-17

    申请人： Jin-Wook Kim

    发明人： Jin-Wook Kim

    IPC分类号： A01G25/16

    CPC分类号： F15B11/04 ,  E02F9/2239 ,  E02F9/2267 ,  E02F9/2282 ,  F15B13/0402 ,  F15B2211/20576 ,  F15B2211/30565 ,  Y10T137/86493

    摘要： hydraulic control valve for a construction machine is provided. The hydraulic control valve includes a boom spool slidingly coupled into a valve block to be shifted to control the hydraulic fluid supplied from a first hydraulic pump and a second hydraulic pump to the actuator and provided with an internal path, a supply path of the first hydraulic pump and a supply path of the second hydraulic pump which are formed to be vertically symmetrical about the boom spool, check valves elastically supported to open and close the supply path of the first hydraulic pump and the supply path of the second hydraulic pump, respectively, bridge paths formed to be horizontally and vertically symmetrical with respect to a path formed on a sliding surface of the valve block to supply the hydraulic fluid, cylinder paths supplying the hydraulic fluid from the first hydraulic pump to the actuator.

    摘要翻译： 提供了一种用于建筑机械的液压控制阀。 液压控制阀包括滑动地联接到阀块中以移动以控制从第一液压泵和第二液压泵供给到致动器的液压流体并设置有内部路径的动臂柱塞，第一液压的供给路径 泵和第二液压泵的供给路径，其形成为围绕悬臂线轴垂直对称，分别弹性支撑以打开和关闭第一液压泵的供给路径和第二液压泵的供给路径的止回阀， 桥接路径形成为相对于形成在阀块的滑动表面上的路径水平和垂直对称以供应液压流体，将液压流体从第一液压泵供应到致动器的气缸路径。