-
公开(公告)号：US10768114B2
公开(公告)日：2020-09-08
申请号：US15501727
申请日：2016-04-29
发明人： Kresimir Franjic , Siu Wai Jacky Mak , Kai Michael Hynna , Michael Frank Gunter Wood , Piotr Kuchnio , Yusuf Bismilla , Lachlan Noel Holmes , Stewart Bright , Aaron Yu Lai Cheung , Yuri Alexander Kuzyk , Aryeh Benjamin Taub , Sanaz Rezaei
IPC分类号： G01N21/65 , G01B11/24 , G01N21/47 , G01N21/63 , G01N21/64 , G01N21/31 , G01B9/02 , G01N21/35
摘要： A modular system for organic sample analysis is disclosed which includes a sample stage including a support platform and a motorized positioning mechanism mounted on the support platform, and a sample holder mounted on the motorized positioning mechanism upon which a sample is placed. A probe support rack is mounted on the support platform and two or more bio-imaging probes mounted on the probe support and arranged in a pre-defined geometry with respect to each other, and at least one bio-imaging probe has a field of view independent of all other bio-imaging probes. The system includes a computer controller connected to the motorized positioning mechanism and the two or more bio-imaging probes. The computer is programmed for controlling motorized positioning mechanism to move the sample holder having the sample located thereon to positions in the field of view of each bio-imaging probe where the sample can be analyzed individually by each of the bio-imaging probes. The computer includes a storage medium for storing an imaging data from each bio-imaging probe. The computer is programmed for spatially correlating imaging data of the selected volume of interest with the imaging data obtained from at least one other bio-imaging probe and storing the spatially correlated imaging data in the computer storage medium.
-
2.发明申请公开(公告)号：US20200029796A1
公开(公告)日：2020-01-30
申请号：US16534392
申请日：2019-08-07
IPC分类号： A61B1/07 , B33Y10/00 , B33Y80/00 , A61B1/00 , A61B1/04 , A61B1/05 , G02B23/24 , G02B6/36 , A61B1/055
摘要： Described are various embodiments of micro-optical surgical probes and micro-optical probe tips and methods of manufacture therefor. In some embodiments, multichannel micro-optical probe tip structures are directly manufactured upon respective optical channel waveguides, or again manufactured to integrally define respective optical coupling to these waveguides. In some embodiments, micro-optical probe tip structures are manufactured via a 3D laser printing process. Specific embodiments include, but are not limited to, spectroscopic or particularly Raman spectroscopy probes and their associated multichannel probe tip structures, and multichannel endoscopes.
-
公开(公告)号：US10478253B2
公开(公告)日：2019-11-19
申请号：US15533840
申请日：2017-01-16
发明人： Siu Wai Jacky Mak
摘要： Systems and methods are provided for identifying a suitable surgical location and/or trajectory for proceeding with a surgical procedure based on local polarization-sensitive optical coherence tomography imaging (PSOCT). PSOCT images are obtained of a tissue region and are processed to provide a spatial map of anisotropic structure within the tissue region. The anisotropic structure is processed to determine one or more suitable surgical locations and/or trajectories for avoiding or reducing damage to local anisotropic tissue structure identified within the tissue region. The spatial map of the anisotropic structure is registered with pre-operative volumetric image data identifying anisotropic tissue structure within a second tissue region that is larger than the tissue region imaged by PSOCT.
-
公开(公告)号：US20180325620A1
公开(公告)日：2018-11-15
申请号：US16026678
申请日：2018-07-03
IPC分类号： A61B90/00 , H04N5/232 , H04N5/238 , H04N13/139 , A61B34/20
CPC分类号： A61B90/37 , A61B34/20 , A61B2034/2057 , A61B2090/367 , G03B9/06 , H04N5/23232 , H04N5/238 , H04N13/139
摘要： A surgical camera system is provided which includes a plurality of imaging devices each having a tunable iris configured to change between at least two different sized numerical apertures. A video stream is produced at a frame rate greater than or equal to about 20 frames per second from first and second images produced by respective sensors and tunable irises of at least two of the imaging devices, the tunable irises controlled to different numerical apertures, the first images acquired at a respective first numerical aperture of a first imaging device and the second images acquired at a respective second numerical aperture of a second imaging device, different from the respective first numerical aperture. The video stream alternates between the first images and the second images so that the video stream results in a three-dimensional effect at a display device when the video stream is rendered thereon.
-
公开(公告)号：US20160061808A1
公开(公告)日：2016-03-03
申请号：US14491158
申请日：2014-09-19
发明人： Aaron Cheung , Siu Wai Jacky Mak , Michael Wood , Cameron Piron
IPC分类号： G01N33/483 , A61B10/02 , G01N21/27 , G01N21/65 , G01N21/47
CPC分类号： G01N1/286 , A61B5/0075 , A61B5/4064 , A61B5/4836 , A61B10/0266 , G01N1/08 , G01N1/31 , G01N21/65 , G01N33/4833 , G01N2201/06113 , G01N2201/0826
摘要： The present invention provides a method and system for identification and isolation of cells from tissues using optical spectroscopy. The method includes accessing the cells using an access corridor, measuring the cells using optical spectroscopy, comparing the spectra of the cells to signature spectra, using the comparison to identify the cells and removing the cells into a container. The system includes an access corridor, a probe for measuring the cells, a resection tool, a collection tube and a collection container.
摘要翻译： 本发明提供一种使用光谱鉴定和分离细胞从组织中分离的方法和系统。 该方法包括使用存取走廊访问细胞，使用光谱法测量细胞，将细胞的光谱与特征谱进行比较，使用比较来鉴定细胞并将细胞移入容器中。 该系统包括通道走廊，用于测量细胞的探针，切除工具，收集管和收集容器。
-
公开(公告)号：US10529096B2
公开(公告)日：2020-01-07
申请号：US15910557
申请日：2018-03-02
摘要： A system and method for characterizing tissue organization using polarization sensitive optical coherence (PSOCT) tomography is provided. A PSOCT device is controlled, by a computing device, to obtain PSOCT A-line scans across a sample. For each of the PSOCT A-line scans, the computing device determines a frequency characteristic of any banding present in a respective PSOCT A-line retardance scan. The computing device controls display device to render a map of the frequency characteristic.
-
7.发明授权公开(公告)号：US10413167B2
公开(公告)日：2019-09-17
申请号：US15607853
申请日：2017-05-30
IPC分类号： G02B23/24 , A61B1/07 , A61B1/055 , A61B1/00 , A61B1/04 , A61B1/05 , B33Y80/00 , B33Y10/00 , G02B6/24 , A61B90/30 , F21V8/00
摘要： Described are various embodiments of micro-optical surgical probes and micro-optical probe tips and methods of manufacture therefor. In some embodiments, multichannel micro-optical probe tip structures are directly manufactured upon respective optical channel waveguides, or again manufactured to integrally define respective optical coupling to these waveguides. In some embodiments, micro-optical probe tip structures are manufactured via a 3D laser printing process. Specific embodiments include, but are not limited to, spectroscopic or particularly Raman spectroscopy probes and their associated multichannel probe tip structures, and multichannel endoscopes.
-
公开(公告)号：US20170086938A1
公开(公告)日：2017-03-30
申请号：US14899254
申请日：2015-03-27
CPC分类号： A61B90/30 , A61B1/0638 , A61B1/07 , A61B5/0071 , A61B5/0075 , A61B5/0084 , A61B2017/00946 , A61B2034/2055 , A61B2090/306
摘要： The present disclosure provides a conductor-less, shape-able surgical lighting system for use in surgical applications in which a medical clinician, once having established a surgical site, can shape the lighting system to selectively illuminate desired volumes of the surgical site. The system includes one or more preselected lengths of an elongate light emitting member formed of a transparent elastomer matrix material having a glass transition temperature of lower than or substantially equal to room temperature to render the elongate light emitting member bendable and shape-able. Embedded in the transparent elastomer matrix material are particles of a transparent material having a refractive index different from a refractive index of the matrix material dispersed in the elastomer matrix material so that light coupled into the elongate light emitting member is scattered and refracted out of the elongate light emitting member along its length. One end of the elongate light emitting member configured to be coupled to a light source.
-
公开(公告)号：US10764560B2
公开(公告)日：2020-09-01
申请号：US16263128
申请日：2019-01-31
发明人： Piotr Kuchnio , Christopher Thomas Jamieson , Siu Wai Jacky Mak , Tammy Kee-Wai Lee , Yusuf Bismilla , Sam Anthony Leitch
IPC分类号： H04N13/25 , H04N13/246 , H04N13/122 , H04N13/282 , H04N13/239 , H04N13/296
摘要： A system for producing 3D video using first and second cameras on first and second axes. The second camera has a field of view (FOV) overlapping with the first camera's FOV. The second axis is at a convergence angle relative to the first axis. A control computer changes the inter-camera distance by effectively moving the second camera laterally, and changes convergence angle by effectively rotating the second camera. The control computer automatically calculates the inter-camera distance and convergence angle based on the distance of a user to the display screen, working distance of the cameras, zoom settings, and size of the screen, and effectively moves the second camera accordingly. A keystone correction is performed to account for the camera projections, the frames are rotationally aligned, and the corrected/aligned frames are combined to produce a 3D image frame that is displayed on a 3D display screen.
-
公开(公告)号：US10536686B1
公开(公告)日：2020-01-14
申请号：US16053298
申请日：2018-08-02
发明人： William La , Siu Wai Jacky Mak
IPC分类号： H04N13/239 , G02B27/10 , G02B3/14 , G02B27/14 , G02B27/00 , H04N13/156 , A61B90/00 , H04N13/296
摘要： An exoscope with enhanced depth of field imaging is provided. The exoscope includes first and second sets of optical devices, the first set having a fixed image plane, the second set having a variable image plane adjacent the fixed image plane of the first set. The second set includes at least one variable device configured to change the position of the variable image plane. A beamsplitter splits light from a combined optical path of the first and second set to respective image devices of the first and second set of optical devices. A controller controls the at least one variable device to change the position of the variable image plane relative to the fixed image plane, combines images acquired by the respective image devices, and controls a display device to render a combined image.
-
-
-
-
-
-
-
-
-
搜索结果
15 条记录 (耗时 0.016 秒)