CAPILLARY ARRAY APPARATUS, METHOD OF MANUFACTURING THE SAME, AND ELECTROPHORESIS ANALYSIS METHOD
    1.
    发明申请
    CAPILLARY ARRAY APPARATUS, METHOD OF MANUFACTURING THE SAME, AND ELECTROPHORESIS ANALYSIS METHOD 审中-公开
    毛细管阵列装置,其制造方法和电泳分析方法

    公开(公告)号:US20080302665A1

    公开(公告)日:2008-12-11

    申请号:US12189629

    申请日:2008-08-11

    IPC分类号: G01N27/26 B29C65/52

    摘要: An electrophoresis analysis method and apparatus capable of maintaining high reliability upon a repeated use of the same gel. A heat transfer medium selected from the group consisting of solids, liquids and gels is filled in substantially all of the gaps between the electrode and each capillary. A hollow electrode into which a capillary is inserted has a plurality of retaining shapes such that the capillary can be fixed at the center of the electrode. The heat from the capillary can be efficiently dissipated via the electrode, and also the temperature increase in the capillary can be prevented. Further, temperature increases due to the heating of the capillaries during operation can be controlled and thereby thermal deterioration of the gel can be prevented.

    摘要翻译: 一种能够在重复使用相同凝胶时保持高可靠性的电泳分析方法和装置。 选自固体,液体和凝胶的传热介质填充在电极和每个毛细管之间的基本上所有的间隙中。 插入有毛细管的中空电极具有多个保持形状,使得毛细管可以固定在电极的中心。 可以通过电极有效地消耗来自毛细管的热量,并且可以防止毛细管中的温度升高。 此外,可以控制由于操作期间毛细管的加热引起的温度升高,从而可以防止凝胶的热劣化。

    Capillary array apparatus, method of manufacturing the same, and electrophoresis analysis method
    2.
    发明授权
    Capillary array apparatus, method of manufacturing the same, and electrophoresis analysis method 有权
    毛细管阵列装置及其制造方法以及电泳分析方法

    公开(公告)号:US07422672B2

    公开(公告)日:2008-09-09

    申请号:US10732221

    申请日:2003-12-11

    IPC分类号: G01N27/453

    摘要: An electrophoresis analysis method and apparatus capable of maintaining high reliability upon a repeated use of the same gel. A heat transfer medium selected from the group consisting of solids, liquids and gels is filled in substantially all of the gaps between the electrode and each capillary. A hollow electrode into which a capillary is inserted has a plurality of retaining shapes such that the capillary can be fixed at the center of the electrode. The heat from the capillary can be efficiently dissipated via the electrode, and also the temperature increase in the capillary can be prevented. Further, temperature increases due to the heating of the capillaries during operation can be controlled and thereby thermal deterioration of the gel can be prevented.

    摘要翻译: 一种能够在重复使用相同凝胶时保持高可靠性的电泳分析方法和装置。 选自固体,液体和凝胶的传热介质填充在电极和每个毛细管之间的基本上所有的间隙中。 插入有毛细管的中空电极具有多个保持形状,使得毛细管可以固定在电极的中心。 可以通过电极有效地消耗来自毛细管的热量,并且可以防止毛细管中的温度升高。 此外,可以控制由于操作期间毛细管的加热引起的温度升高,从而可以防止凝胶的热劣化。

    Analyzer
    8.
    发明授权
    Analyzer 有权
    分析仪

    公开(公告)号:US09393562B2

    公开(公告)日:2016-07-19

    申请号:US13983340

    申请日:2012-01-13

    摘要: Provided is an analyzer capable of reducing the amount of wasted reagents and shortening time required for solution sending, thus increasing throughput for analysis. A microsyringe sucks a minimum required amount of reagent that is substantially the same amount of capacity of a flow cell to a sampling nozzle. Then, the sampling nozzle is inserted into an injection port of the flow cell, and the reagent is injected into the flow cell by driving the microsyringe. The inside of the sampling nozzle is cleaned by moving the sampling nozzle to the cleaning tank and ejecting cleaning water from the sampling nozzle, and the outside of the sampling nozzle is cleaned by spraying cleaning water from an inner wall of the cleaning tank.

    摘要翻译: 提供了能够减少试剂浪费量和溶液发送所需时间缩短的分析装置,从而提高分析用量。 微量注射器将最小所需量的试剂吸收到与采样喷嘴相当的流动池的容量基本上相同的量。 然后,将取样喷嘴插入流通池的注入口,通过驱动微量注射器将试剂注入到流通池中。 通过将采样喷嘴移动到清洗槽并从采样喷嘴喷射清洗水来清洁采样喷嘴的内部,并且通过从清洗槽的内壁喷射清洁水来清洁采样喷嘴的外部。

    Capillary electrophoresis apparatus
    9.
    发明授权
    Capillary electrophoresis apparatus 有权
    毛细管电泳仪

    公开(公告)号:US08702949B2

    公开(公告)日:2014-04-22

    申请号:US13263040

    申请日:2010-04-08

    IPC分类号: G01N27/453

    CPC分类号: G01N27/44743 G01N27/44782

    摘要: The solution reservoir apparatus of the capillary electrophoresis apparatus securely affixes an evaporation-preventing membrane to a container when a capillary is inserted or withdrawn, without extending the cathode end of the capillary. The solution reservoir apparatus comprises a container for reserving a sample or solution, a cover having a bore through which the capillary is passed and covering the container, an evaporation-preventing membrane having a capillary hole through which the capillary is passed, and a container holder for holding the container. The evaporation-preventing membrane has a projection provided at the periphery of the capillary hole, the projection of the evaporation-preventing membrane is engaged with the bore on the cover when the evaporation-preventing membrane is positioned on the cover, and the evaporation-preventing membrane is supported by the cover.

    摘要翻译: 当毛细管插入或取出时,毛细管电泳装置的溶液储存装置在不延长毛细管的阴极端的情况下,将防蒸发膜牢固地固定在容器上。 溶液储存装置包括用于储存样品或溶液的容器,具有孔的盖,毛细管穿过孔覆盖容器,具有毛细孔通过的毛细孔的防蒸发膜和容器保持架 用于拿着容器。 防蒸发膜具有设置在毛细孔周边的突起,当防蒸发膜位于盖上时,防蒸发膜的突起与盖上的孔接合,并且防蒸发膜 膜由盖支撑。

    Multi-capillary array electrophoresis device
    10.
    发明授权
    Multi-capillary array electrophoresis device 有权
    多毛细管阵列电泳装置

    公开(公告)号:US08246806B2

    公开(公告)日:2012-08-21

    申请号:US11714222

    申请日:2007-03-06

    IPC分类号: G01N27/453

    CPC分类号: G01N27/44782 G01N27/44721

    摘要: An electrophoresis apparatus includes a multi-capillary array having a liquid or solid disposed between the capillaries of the array. The liquid or solid exhibits a refractive index higher than that of air and less than that of water and reduces the amount of laser beams scattered by the capillaries. Also provided are methods of adjusting refracted and reflected excitation light beams passing through capillaries of a multi-capillary array, to reduce loss of intensity of the laser beams and increase irradiation of respective samples disposed in the capillaries.

    摘要翻译: 电泳装置包括具有设置在阵列的毛细管之间的液体或固体的多毛细管阵列。 液体或固体的折射率高于空气的折射率,小于水的折射率,并减少了由毛细管散射的激光束的数量。 还提供了调节通过多毛细管阵列的毛细管的折射和反射的激发光束的方法,以减少激光束的强度损失并增加设置在毛细管中的各个样品的照射。