公开(公告)号：US20220380834A1

公开(公告)日：2022-12-01

申请号：US17282305

申请日：2019-10-04

Applicant: T2 Biosystems, Inc.

Inventor： Jessica Lee SNYDER ,  Brendan John MANNING ,  Daniel GAMERO ,  Heidi Susanne GIESE ,  Thomas J. LOWERY, Jr.

IPC: C12Q1/689 ,  G01N27/74

Abstract: Provided herein are methods of amplifying and detecting drug resistance markers (e.g., antibiotic resistance genes) from pathogens in complex samples (e.g., blood), as well as related panels and compositions (e.g., systems, cartridges, and kits).

公开(公告)号：US20220282310A1

公开(公告)日：2022-09-08

申请号：US17274911

申请日：2019-09-10

Applicant: T2 Biosystems, Inc.

Inventor： Jessica Lee SNYDER ,  Brendan John MANNING ,  Christopher STEELE ,  Roger SMITH ,  Heidi Susanne GIESE ,  Yin Shan Cathy WONG ,  Daniel GAMERO ,  Thomas J. LOWERY, Jr.

IPC: C12Q1/6825 ,  C12Q1/6869 ,  C12Q1/6806

Abstract: Provided herein are methods of detecting and sequencing target nucleic acids in complex samples (e.g., blood), as well as related panels and compositions (e.g., systems, cartridges, and kits).

公开(公告)号：US20220228199A1

公开(公告)日：2022-07-21

申请号：US17713456

申请日：2022-04-05

Applicant: T2 Biosystems, Inc.

Inventor： Ulrich Hans THOMANN ,  Lori Anne NEELY ,  Rahul Krishan DHANDA ,  Frédéric SWEENEY ,  Thomas Jay LOWERY, JR. ,  Jessica Ann TOWNSEND ,  Jessica Lee SNYDER ,  Heidi Susanne GIESE ,  Cheryl Ann BANDOSKI-GRALINSKI ,  Daniella Lynn LOGAN

IPC: C12Q1/689 ,  C12N15/10 ,  G01N24/08

Abstract: The invention features methods, systems, and panels for rapid detection of tick-borne pathogens in a sample (including Borrelia spp. such as B. burgdorferi, B. afzelii, and B. garinii) and for diagnosis and monitoring of tick-transmitted diseases, including Lyme disease, Rocky Mountain spotted fever, Q-fever, babesiosis, ehrlichiosis, tularemia, and anaplasmosis.

公开(公告)号：US20180171388A1

公开(公告)日：2018-06-21

申请号：US15545663

申请日：2016-01-21

Applicant: T2 Biosystems, Inc.

Inventor： Ulrich Hans THOMANN ,  Lori Anne NEELY ,  Rahul Krishan DHANDA ,  Frédéric SWEENEY ,  Thomas Jay LOWERY, JR. ,  Jessica Ann TOWNSEND ,  Jessica Lee SNYDER ,  Heidi Susanne GIESE ,  Cheryl Ann BANDOSKI-GRALINSKI ,  Daniella Lynn LOGAN

IPC: C12Q1/689 ,  G01N24/08 ,  C12N15/10

CPC classification number: C12Q1/689 ,  C12N15/1013 ,  C12Q2600/112 ,  C12Q2600/124 ,  C12Q2600/156 ,  G01N24/08 ,  G01N2333/20 ,  G01N2800/26 ,  Y02A50/57

Abstract: The invention features methods, systems, and panels for rapid detection of tick-borne pathogens in a sample (including Borrelia spp. such as B. burgdorferi, B. afzelii, and B. garinii) and for diagnosis and monitoring of tick-transmitted diseases, including Lyme disease, Rocky Mountain spotted fever, Q-fever, babesiosis, ehrlichiosis, tularemia, and anaplasmosis.

公开(公告)号：US20240026415A1

公开(公告)日：2024-01-25

申请号：US18049514

申请日：2022-10-25

Applicant: T2 Biosystems, Inc.

Inventor： Ulrich Hans THOMANN ,  Lori Anne NEELY ,  Heidi Susanne GIESE ,  Jessica Ann TOWNSEND ,  Rahul Krishan DHANDA ,  Thomas Jay LOWERY, JR. ,  Urvi VED ,  Brendan MANNING ,  Nu Ai PHUNG ,  Joanne Lawton GARVER ,  Benjamin B. STONE

IPC: C12Q1/04 ,  C07K14/22 ,  C12Q1/689 ,  G01N33/569 ,  G01N33/68 ,  C12Q1/6825

CPC classification number: C12Q1/04 ,  C07K14/22 ,  C12Q1/689 ,  G01N33/56911 ,  G01N33/6893 ,  C12Q1/6825 ,  C12Q2600/158 ,  C12Q2600/16

Abstract: The invention features methods, panels, cartridges, and systems for detecting pathogens and for diagnosing and treating diseases, including bacteremia and sepsis.

公开(公告)号：US20190071707A1

公开(公告)日：2019-03-07

申请号：US16070994

申请日：2017-01-20

Applicant: T2 Biosystems, Inc.

Inventor： Ulrich Hans THOMANN ,  Lori Anne NEELY ,  Heidi Susanne GIESE ,  Jessica Ann TOWNSEND ,  Rahul Krishan DHANDA ,  Thomas Jay LOWERY, Jr. ,  Urvi VED ,  Brendan MANNING ,  Nu Ai PHUNG ,  Joanne Lawton GARVER ,  Benjamin B. STONE

IPC: C12Q1/04 ,  C07K14/22 ,  C12Q1/689

Abstract: The invention features methods panels, cartridges, and systems for detecting pathogens and for diagnosing and treating diseases, including bacteremia and sepsis.