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Patent Agency Ranking
公开(公告)号：US20160018421A1
公开(公告)日：2016-01-21
申请号：US14803577
申请日：2015-07-20
Applicant: T2 Biosystems, Inc.
Inventor： Thomas Jay LOWERY, JR. , Vyacheslav PAPKOV , Walter W. MASSEFSKI, JR. , Rahul K. DHANDA , Edward Chris THAYER
CPC classification number: G01N33/86 , A61B5/02007 , A61B5/0263 , A61B5/7246 , A61M1/10 , A61M1/1086 , A61M1/12 , A61M1/122 , A61M2205/33 , A61M2205/3303 , A61M2230/20 , A61M2230/207 , G01N24/08 , G01N24/088 , G01N2800/226 , G01N2800/52 , G01R33/448 , G06F19/00 , Y02A90/26
Abstract: The invention features a method of monitoring a clotting process by measuring a signal characteristic of the NMR relaxation of water in a sample undergoing clotting to produce NMR relaxation data and determining from the NMR relaxation data a magnetic resonance parameter of water in the sample characteristic of the clots being formed.
Abstract translation: 本发明的特征在于一种监测凝血过程的方法，该方法是通过测量在经历凝结的样品中的水的NMR松弛的信号特征，从而产生NMR弛豫数据，并根据NMR弛豫数据确定样品特征中的水的磁共振参数 凝块形成。
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公开(公告)号：US20180188195A1
公开(公告)日：2018-07-05
申请号：US15738754
申请日：2016-06-27
Applicant: T2 Biosystems, Inc.
Inventor： Eugenio DAVISO , Lucius (Tad) FOX , Thomas Jay LOWERY, Jr. , Joseph MARTURANO , Vyacheslav PAPKOV , Al SCHROFF , Roger SMITH , Zhixiang LUO
CPC classification number: G01N24/088 , C12Q1/56 , G01N24/08 , G01N2333/974 , G01R33/448
Abstract: The invention features a diagnostic platform utilizing T2 magnetic resonance to directly measure integrated reactions in whole blood samples such as clotting, fibrinogen, clot contraction, and fibrinolysis to provide a comprehensive assessment of hemostatic parameters on a single instrument in minutes. The methods of the invention can be performed with less than 1 ml of blood and minimal sample handling.
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公开(公告)号：US20170045494A1
公开(公告)日：2017-02-16
申请号：US15306901
申请日：2015-04-27
Applicant: T2 Biosystems, Inc.
CPC classification number: G01N33/4905 , A61B5/055 , G01N24/08 , G01R33/448
Abstract: The invention features a diagnostic platform utilizing T2 magnetic resonance to directly measure integrated reactions in whole blood samples such as clotting, clot contraction, and fibrinolysis to provide a comprehensive assessment of hemostatic parameters on a single instrument in minutes. The methods of the invention can be performed with less than 1 mL of blood and minimal sample handling.
Abstract translation: 本发明的特征在于利用T2磁共振来直接测量全血样品中的整体反应如凝血，凝块收缩和纤维蛋白溶解的诊断平台，以便在几分钟内在单个仪器上综合评估止血参数。 本发明的方法可以用少于1mL的血液和最小的样品处理进行。
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公开(公告)号：US20180113141A1
公开(公告)日：2018-04-26
申请号：US15717113
申请日：2017-09-27
Applicant: T2 Biosystems, Inc.
Inventor： Thomas Jay LOWERY, Jr. , Vyacheslav PAPKOV , Walter W. MASSEFSKI, Jr. , Rahul K. DHANDA , Edward Chris THAYER
Abstract: The invention features a method of monitoring a clotting process by measuring a signal characteristic of the NMR relaxation of water in a sample undergoing clotting to produce NMR relaxation data and determining from the NMR relaxation data a magnetic resonance parameter of water in the sample characteristic of the clots being formed.
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公开(公告)号：US20170315141A1
公开(公告)日：2017-11-02
申请号：US15526086
申请日：2015-11-12
Applicant: T2 Biosystems, Inc.
Inventor： Thomas Jay LOWERY, JR. , Vyacheslav PAPKOV , Walter W. MASSEFSKI, JR.
IPC: G01N33/80 , G01N33/542
CPC classification number: G01N33/80 , G01N33/542 , G01N33/54373
Abstract: The invention features systems and methods for the detection of analytes, particularly antigens, complement, and antibodies present in blood. The invention features a system for the detection of antigens, complement, and antibodies on the surface of RBCs and circulating antibodies in the blood.
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