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    Chemically sensitive field effect transistors and uses thereof in electronic nose devices
    5.
    发明授权
    Chemically sensitive field effect transistors and uses thereof in electronic nose devices 有权

    公开(公告)号：US11243186B2

    公开(公告)日：2022-02-08

    申请号：US16000121

    申请日：2018-06-05

    Applicant: TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD.

    Inventor： Hossam Haick

    IPC: G01N27/414 ,  H01L29/772 ,  B82Y15/00 ,  B82Y30/00 ,  G01N33/543 ,  H01L29/08 ,  G01N33/00 ,  G01N33/497

    Abstract: A system having an electronic device. The electronic device has an array of chemically sensitive sensors. The sensors detect volatile organic compounds and have field effect transistors. The transistors have non-oxidized, functionalized silicon nanowires. The nanowires have surface Si atoms. The device has a plurality of functional groups that form a direct Si—C bond with the silicon nanowires, wherein Si is a surface Si atom and C is a carbon atom of the functional group. The functional groups are selected from the group consisting of: alkyl, cycloalkyl, alkenyl, alkynyl, aryl, heterocyclyl, heteroaryl, alkylaryl, alkylalkenyl, alkylalkynyl, alkylcycloalkyl, alkylheterocyclyl and alkylheteroaryl groups, and derivatives thereof, wherein said functional groups are other than methyl and 1-butyl. The plurality of functional groups are attached to 50-100% of the surface Si atoms.

    CHEMICALLY SENSITIVE FIELD EFFECT TRANSISTORS AND USES THEREOF IN ELECTRONIC NOSE DEVICES
    6.
    发明申请
    CHEMICALLY SENSITIVE FIELD EFFECT TRANSISTORS AND USES THEREOF IN ELECTRONIC NOSE DEVICES 审中-公开

    公开(公告)号：US20180282155A1

    公开(公告)日：2018-10-04

    申请号：US16000121

    申请日：2018-06-05

    Applicant: TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD.

    Inventor： Hossam Haick

    IPC: B82Y15/00

    Abstract: A system having an electronic device. The electronic device has an array of chemically sensitive sensors. The sensors detect volatile organic compounds and have field effect transistors. The transistors have non-oxidized, functionalized silicon nanowires. The nanowires have surface Si atoms. The device has a plurality of functional groups that form a direct Si—C bond with the silicon nanowires, wherein Si is a surface Si atom and C is a carbon atom of the functional group. The functional groups are selected from the group consisting of: alkyl, cycloalkyl, alkenyl, alkynyl, aryl, heterocyclyl, heteroaryl, alkylaryl, alkylalkenyl, alkylalkynyl, alkylcycloalkyl, alkylheterocyclyl and alkylheteroaryl groups, and derivatives thereof, wherein said functional groups are other than methyl and 1-butyl. The plurality of functional groups are attached to 50-100% of the surface Si atoms.

    BREATH ANALYSIS OF PULMONARY NODULES
    8.
    发明申请
    BREATH ANALYSIS OF PULMONARY NODULES 有权
    肺动脉分泌物的分析

    公开(公告)号：US20130150261A1

    公开(公告)日：2013-06-13

    申请号：US13678126

    申请日：2012-11-15

    Applicant: Technion Research and Development Foundation Ltd. ,  Tel Hashomer Medical Research, Infrastructure and Services Ltd.

    Inventor： Hossam Haick ,  Nir Peled

    IPC: G01N33/497

    CPC classification number: G01N33/497 ,  G01N33/0034 ,  G01N2800/7028

    Abstract: The present invention provides a unique profile of volatile organic compounds as breath biomarkers for lung cancer. The present invention further provides the diagnosis, prognosis and monitoring of lung cancer or predicting the response to an anti-cancer treatment through the detection of the unique profile of volatile organic compounds indicative of lung cancer at its various stages.

    Abstract translation: 本发明提供挥发性有机化合物作为肺癌呼吸生物标志物的独特特征。 本发明还通过检测其各种阶段的指示肺癌的挥发性有机化合物的独特特征，进一步提供对肺癌的诊断，预后和监测或预测对抗癌治疗的反应。

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