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公开(公告)号:US11427798B2
公开(公告)日:2022-08-30
申请号:US16868474
申请日:2020-05-06
Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Inventor: Jered Haun , Janice De Jesus , Elliot En-Yu Hui , Jiang Li
Abstract: A tissue dissociation device includes an inlet coupled to a first stage having a single channel having an upstream end and a downstream end; a plurality of serially arranged intermediate stages, wherein a first intermediate stage of the plurality is fluidically coupled to the downstream end of the first stage, and wherein each subsequent intermediate stage of the plurality has an increasing number of channels (with channels of smaller dimensions); and an outlet coupled to a last stage of the intermediate stages.
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公开(公告)号:US20170131187A1
公开(公告)日:2017-05-11
申请号:US15413201
申请日:2017-01-23
Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Inventor: Jered Haun , Janice De Jesus , Elliot En-Yu Hui , Jiang Li
IPC: G01N1/28
Abstract: A tissue dissociation device includes an inlet coupled to a first stage having a single channel having an upstream end and a downstream end; a plurality of serially arranged intermediate stages, wherein a first intermediate stage of the plurality is fluidically coupled to the downstream end of the first stage, and wherein each subsequent intermediate stage of the plurality has an increasing number of channels (with channels of smaller dimensions); and an outlet coupled to a last stage of the intermediate stages.
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公开(公告)号:US10683480B2
公开(公告)日:2020-06-16
申请号:US15413201
申请日:2017-01-23
Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Inventor: Jered Haun , Janice De Jesus , Elliot En-Yu Hui , Jiang Li
Abstract: A tissue dissociation device includes an inlet coupled to a first stage having a single channel having an upstream end and a downstream end; a plurality of serially arranged intermediate stages, wherein a first intermediate stage of the plurality is fluidically coupled to the downstream end of the first stage, and wherein each subsequent intermediate stage of the plurality has an increasing number of channels (with channels of smaller dimensions); and an outlet coupled to a last stage of the intermediate stages.
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公开(公告)号:US20200283723A1
公开(公告)日:2020-09-10
申请号:US16868474
申请日:2020-05-06
Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Inventor: Jered Haun , Janice De Jesus , Elliot En-Yu Hui , Jiang Li
Abstract: A tissue dissociation device includes an inlet coupled to a first stage having a single channel having an upstream end and a downstream end; a plurality of serially arranged intermediate stages, wherein a first intermediate stage of the plurality is fluidically coupled to the downstream end of the first stage, and wherein each subsequent intermediate stage of the plurality has an increasing number of channels (with channels of smaller dimensions); and an outlet coupled to a last stage of the intermediate stages.
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公开(公告)号:US09580678B2
公开(公告)日:2017-02-28
申请号:US14309720
申请日:2014-06-19
Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Inventor: Jered Haun , Janice De Jesus , Elliot En-Yu Hui , Jiang Li
CPC classification number: G01N1/286 , B01L3/502753 , B01L2300/0816 , B01L2300/0864 , B01L2300/0887 , B01L2400/0487 , B01L2400/086 , C12M21/08 , C12M21/18 , C12M45/02 , C12M47/04
Abstract: A tissue dissociation device includes an inlet coupled to a first stage having a single channel having an upstream end and a downstream end; a plurality of serially arranged intermediate stages, wherein a first intermediate stage of the plurality is fluidically coupled to the downstream end of the first stage, and wherein each subsequent intermediate stage of the plurality has an increasing number of channels (with channels of smaller dimensions); and an outlet coupled to a last stage of the intermediate stages.
Abstract translation: 组织解离装置包括连接到具有具有上游端和下游端的单个通道的第一级的入口; 多个串联布置的中间级,其中多个第一中间级流体耦合到第一级的下游端,并且其中多个的每个后续中间级具有越来越多的通道(具有较小尺寸的通道) ; 以及连接到中间级的最后阶段的出口。
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公开(公告)号:US20140377866A1
公开(公告)日:2014-12-25
申请号:US14309720
申请日:2014-06-19
Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Inventor: Jered Haun , Janice De Jesus , Elliot En-Yu Hui , Jiang Li
CPC classification number: G01N1/286 , B01L3/502753 , B01L2300/0816 , B01L2300/0864 , B01L2300/0887 , B01L2400/0487 , B01L2400/086 , C12M21/08 , C12M21/18 , C12M45/02 , C12M47/04
Abstract: A tissue dissociation device includes an inlet coupled to a first stage having a single channel having an upstream end and a downstream end; a plurality of serially arranged intermediate stages, wherein a first intermediate stage of the plurality is fluidically coupled to the downstream end of the first stage, and wherein each subsequent intermediate stage of the plurality has an increasing number of channels (with channels of smaller dimensions); and an outlet coupled to a last stage of the intermediate stages.
Abstract translation: 组织解离装置包括连接到具有具有上游端和下游端的单个通道的第一级的入口; 多个串联布置的中间级,其中多个第一中间级流体耦合到第一级的下游端,并且其中多个的每个后续中间级具有越来越多的通道(具有较小尺寸的通道) ; 以及连接到中间级的最后阶段的出口。
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