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公开(公告)号：US11033605B2
公开(公告)日：2021-06-15
申请号：US15617345
申请日：2017-06-08
Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Inventor： B. Chia Soo , Kang Ting , Zhong Zheng
Abstract: Provided herein is a method of promoting tissue repair, comprising delivering to a subject a therapeutically effective amount of fibromodulin (FMOD), FMOD polypeptide, FMOD peptide, or a variant or derivative or analog thereof according to a dosing regimen to cause an injured tissue to form a repaired tissue having an improved condition provided that the improved condition does not include improved condition of scar of skin.
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公开(公告)号：US20210128791A1
公开(公告)日：2021-05-06
申请号：US17073945
申请日：2020-10-19
Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Inventor： B. Chia Soo , Kang Ting , Zhong Zheng , Benjamin Wu , Yulong Zhang
Abstract: The application discloses an implantable device, comprising a galvanic redox system formed on a body substrate of the implantable device. The implantable device has a non-zero surface potential when it is deployed. The galvanic redox system comprises a first metal site and a second metal site, the first metal site comprising a first metal having a first metal electrode potential (FMEP) and the second metal site comprising a second metal having a second metal electrode potential (SMEP), which FMEP being lower than SMEP and SMEP being substantially different such that the implantable device is galvanized when it is deployed. Methods of making and using the implantabe device are also disclosed.
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公开(公告)号：US20140369971A1
公开(公告)日：2014-12-18
申请号：US14353284
申请日：2012-10-22
Applicant: The Regents of the University of California
Inventor： B. Chia Soo , Kang Ting , Zhong Zheng
CPC classification number: C12N5/0696 , A61K35/12 , A61K35/33 , A61K38/1709 , A61K38/18 , C07K14/435 , C12N5/06 , C12N2501/15 , C12N2501/998 , C12N2506/00 , C12N2506/13 , C12N2506/1307
Abstract: The present invention provides a fibromodulin (FMOD) reprogrammed (FReP) cell and a method of making therefor, a culture medium therefor, and a supernatant thereof, and methods of making and using these.
Abstract translation: 本发明提供了一种纤维调节素（FMOD）重编程（FROD）细胞及其制备方法，其培养基及其上清液，以及制备和使用它们的方法。
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公开(公告)号：US12144843B2
公开(公告)日：2024-11-19
申请号：US16928724
申请日：2020-07-14
Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Inventor： B. Chia Soo , Kang Ting , Zhong Zheng
Abstract: The present invention discloses methods and compositions for treating or ameliorating a condition associated with increased or decreased myofibroblast activities and use thereof.
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公开(公告)号：US10729747B2
公开(公告)日：2020-08-04
申请号：US16405782
申请日：2019-05-07
Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Inventor： B. Chia Soo , Kang Ting , Zhong Zheng
Abstract: The present invention discloses methods and compositions for treating or ameliorating a condition associated with increased or decreased myofibroblast activities and use thereof.
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Patent Agency Ranking
公开(公告)号：US20170159021A1
公开(公告)日：2017-06-08
申请号：US15383752
申请日：2016-12-19
Applicant: The Regents of the University of California
Inventor： B. Chia SOO , Kang TING , Zhong Zheng
CPC classification number: C12N5/0696 , A61K35/12 , A61K35/33 , A61K38/1709 , A61K38/18 , C07K14/435 , C12N5/06 , C12N2501/15 , C12N2501/998 , C12N2506/00 , C12N2506/13 , C12N2506/1307
Abstract: The present invention provides a method of forming a fibromodulin (FMOD) reprogrammed (FReP) cell.This application includes the sequence listing which is identical to the sequence information in the last filed computer readable form (CFR) on Aug. 1, 2014 in U.S. application Ser. No. 14/353,284, filed Apr. 21, 2014, entitled “2014-08-01 384578-991391 ST25.tax” and is hereby incorporated by reference in its entirety.
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公开(公告)号：US20230002738A1
公开(公告)日：2023-01-05
申请号：US17679745
申请日：2022-02-24
Applicant: The Regents of The University of California
Inventor： B. Chia Soo , Kang Ting , Zhong Zheng
Abstract: The present invention provides a method of treating a disorder using a fibromodulin (FMOD) reprogrammed (FReP) cell. The method comprises administering locally to a human being the FReP cell to a site in need thereof of the human being.
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公开(公告)号：US10279010B2
公开(公告)日：2019-05-07
申请号：US15673880
申请日：2017-08-10
Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Inventor： B. Chia Soo , Kang Ting , Zhong Zheng
Abstract: The present invention discloses methods and compositions for treating or ameliorating a condition associated with increased or decreased myofibroblast activities and use thereof.
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公开(公告)号：US09885014B2
公开(公告)日：2018-02-06
申请号：US13677186
申请日：2012-11-14
Applicant: The Regents of the University of California
Inventor： Kang Ting , B. Chia Soo , Zhong Zheng
IPC: C12N5/00 , A61K35/545 , C12N5/074
CPC classification number: C12N5/0018 , A61K35/545 , C12N5/0696 , C12N2501/998
Abstract: The present invention provides pluripotent stem cell like (PSCL) cells or clones, a culture medium therefore, and a supernatant thereof, and methods of making and using the same.
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公开(公告)号：US09549954B2
公开(公告)日：2017-01-24
申请号：US14353284
申请日：2012-10-22
Applicant: The Regents of the University of California
Inventor： B. Chia Soo , Kang Ting , Zhong Zheng
IPC: C12N5/08 , C12N5/02 , A01N63/00 , C07K1/00 , A61K35/33 , A61K35/12 , A61K38/18 , C12N5/074 , A61K38/17 , C12N5/07
CPC classification number: C12N5/0696 , A61K35/12 , A61K35/33 , A61K38/1709 , A61K38/18 , C07K14/435 , C12N5/06 , C12N2501/15 , C12N2501/998 , C12N2506/00 , C12N2506/13 , C12N2506/1307
Abstract: The present invention provides a fibromodulin (FMOD) reprogrammed (FReP) cell and a method of making therefor, a culture medium therefor, and a supernatant thereof, and methods of making and using these.
Abstract translation: 本发明提供了一种纤维调节素（FMOD）重编程（FROD）细胞及其制备方法，其培养基及其上清液，以及制备和使用它们的方法。
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