利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

62 条记录 (耗时 0.026 秒)

    Process for production of .beta.-dihalogenoethenylcyclopropane derivatives
    1.
    发明授权
    Process for production of .beta.-dihalogenoethenylcyclopropane derivatives 失效
    生产β-二卤代乙酰基环丙烷衍生物的方法

    公开(公告)号：US4740612A

    公开(公告)日：1988-04-26

    申请号：US825966

    申请日：1986-02-05

    申请人： Takashi Matsuo ,  Nobushige Itaya ,  Osamu Magara

    发明人： Takashi Matsuo ,  Nobushige Itaya ,  Osamu Magara

    IPC分类号： C07C69/743 ,  A01N37/06 ,  A01P7/04 ,  C07C20060101 ,  C07C23/04 ,  C07C49/16 ,  C07C49/163 ,  C07C49/327 ,  C07C51/377 ,  C07C61/15 ,  C07C61/35 ,  C07C61/40 ,  C07C62/18 ,  C07C67/00 ,  C07C69/74 ,  C07C69/747 ,  C07C69/757

    CPC分类号： C07C45/65 ,  C07C45/69

    摘要： A novel process for producing a .beta.-dihalogenoethenylcyclopropane derivative of the formula, ##STR1## wherein R.sub.1 is a hydrogen atom or an alkyl group, R.sub.3 is a hydrogen atom, lower alkyl, acyl, carboxyl or alkoxycarbonyl group and R is a hydrogen atom or a lower alkyl group and each of Y.sub.1 and Y.sub.2 is a fluorine, chlorine or bromine atom respectively, which is an acidic moiety of the useful synthetic insecticides of the pyrethrin type, which process comprises a combination of a series of sequential steps starting from alkyl 3-butenyl ketone derivative of the formula (I), which may be shown according to the following reaction scheme: ##STR2## According to this process, objective compound of the formula (VI) having any cis/trans ratio can be produced by selecting the reaction condition of the Stages II-1, II-2, and IV-2.

    摘要翻译： 一种制备下式的β-二卤代乙酰基环丙烷衍生物的新方法，其中R1是氢原子或烷基，R3是氢原子，低级烷基，酰基，羧基或烷氧基羰基，R是氢原子或 低级烷基，Y1和Y2各自分别是氟，氯或溴原子，它们是除虫菊酯类有用的合成杀虫剂的酸性部分，该方法包括从烷基3开始的一系列顺序步骤的组合 （VI）的目标化合物，其具有任何顺式（Ⅵ）的式（Ⅵ）的化合物， /反式比可以通过选择阶段II-1，II-2和IV-2的反应条件来产生。

    Method for preparing 4-hydroxy-3-methyl-2-(2-propynyl)-2-cyclopentenolone
    4.
    发明授权
    Method for preparing 4-hydroxy-3-methyl-2-(2-propynyl)-2-cyclopentenolone 失效
    4-羟基-3-甲基-2-（2-丙炔基）-2-环戊烯醇的制备方法

    公开(公告)号：US4343953A

    公开(公告)日：1982-08-10

    申请号：US159497

    申请日：1980-06-16

    申请人： Noritada Matsuo ,  Nobushige Itaya ,  Kohichi Aketa ,  Osamu Magara ,  Toshio Nishioka

    发明人： Noritada Matsuo ,  Nobushige Itaya ,  Kohichi Aketa ,  Osamu Magara ,  Toshio Nishioka

    IPC分类号： C07C45/66 ,  C07C45/67 ,  C07C45/72 ,  C07C49/24 ,  C07C45/45

    CPC分类号： C07C49/24 ,  C07C45/66 ,  C07C45/673 ,  C07C45/72

    摘要： The present invention relates to a novel method for producing cyclopentenolone of the formula (I), ##STR1## which is a useful intermediate for producing agricultural chemicals, which comprises reacting an acetonedicarboxylic ester of the formula (VII), ##STR2## wherein R is a C.sub.1 -C.sub.6 alkyl group, with 2-propynyl chloride in the presence of magnesium alkoxide and in the presence of alkali iodide to obtain novel mono-(2-propynyl)-substituted acetonedicarboxylic ester of the formula (VI), ##STR3## wherein R is as defined above; hydrolyzing the mono-(2-propynyl)-substituted acetonedicarboxylic ester of the formula (VI) under alkaline conditions with an alkali and then reacting the hydrolyzed product with methylglyoxal of the formula, ##STR4## to obtain novel .gamma.-diketone of the formula (V), ##STR5## and ring-closing the .gamma.-diketone of the formula (V) under alkaline condition.

    摘要翻译： 本发明涉及一种制备式（I）的环戊烯醇酮的新方法，其是用于生产农药的有用的中间体，其包括使式（VII）的丙酮二羧酸酯， （Ⅶ）其中R是C 1 -C 6烷基，与2-丙炔基氯在烷氧基镁存在下，在碱金属碘化物的存在下，得到式（Ⅵ）的新型单 - （2-丙炔基） - 取代的丙酮二羧酸酯 ），其中R如上定义; 在碱性条件下用碱水解式（Ⅵ）的单 - （2-丙炔基） - 取代的丙二酸二羧酸酯，然后使水解产物与下式的甲基乙二醛反应，得到式（Ⅵ）的新的γ-二酮 V），（V）并在碱性条件下闭合式（V）的γ-二酮。

    Process for isomerization of a cyclopropanecarboxylic acid
    5.
    发明授权
    Process for isomerization of a cyclopropanecarboxylic acid 失效
    环丙烷羧酸异构化的方法

    公开(公告)号：US4008268A

    公开(公告)日：1977-02-15

    申请号：US585592

    申请日：1975-06-10

    申请人： Toshio Mizutani ,  Nobushige Itaya ,  Toshiko Nishijima ,  Osamu Magara

    发明人： Toshio Mizutani ,  Nobushige Itaya ,  Toshiko Nishijima ,  Osamu Magara

    IPC分类号： C07C61/40 ,  B01J27/00 ,  C07B61/00 ,  C07C51/00 ,  C07C51/353 ,  C07C67/00 ,  C07C61/18

    CPC分类号： C07C51/353

    摘要： A process for isomerizing 2-(.beta.,.beta.-dichlorovinyl)-3,3-dimethylcyclopropanecarboxylic acid represented by the formula, ##STR1## which comprises heating the acid of the formula (I) in the presence of the anhydride of the acid or a reagent producing the acid anhydride in the reaction system.The ester resulting from 2-(.beta.,.beta.-dichlorovinyl)-3,3-dimethylcyclopropanecarboxylic acid and, for example, 3-phenoxybenzyl alcohol is a compound which has a very wide range of insecticidal spectrum and has a very high controlling effect as a low-toxicity insecticide not only for domestic use and public health but also against insects injurious to agriculture or forestry, and in the case of the 3-phenoxybenzyl ester or 5-benzyl-3-furylmethyl ester of the 2-(.beta.,.beta.-dichlorovinyl)-3,3-dimethylcyclopropanecarboxylic acid, the trans-isomer is lower than the cis-isomer in toxicity to warm-blooded animals.

    摘要翻译： 异构化由式（I）表示的2-（β，β-二氯乙烯基）-3,3-二甲基环丙烷甲酸的方法，其包括在存在下述的酸酐的情况下加热式（I）的酸 酸或在反应体系中产生酸酐的试剂。

    Novel cyclopropanecarboxylates
    6.
    发明授权
    Novel cyclopropanecarboxylates 失效
    新型环丙烷羧酸酯

    公开(公告)号：US4003945A

    公开(公告)日：1977-01-18

    申请号：US461029

    申请日：1974-04-15

    申请人： Shigeyoshi Kitamura ,  Nobushige Itaya ,  Yoshitoshi Okuno ,  Nobuo Ohno ,  Takashi Matsuo ,  Masachika Hirano ,  Toshio Mizutani ,  Hisami Takeda

    发明人： Shigeyoshi Kitamura ,  Nobushige Itaya ,  Yoshitoshi Okuno ,  Nobuo Ohno ,  Takashi Matsuo ,  Masachika Hirano ,  Toshio Mizutani ,  Hisami Takeda

    IPC分类号： C07C69/743 ,  A01N53/10 ,  C07C69/74 ,  C07D307/28 ,  C07D307/45 ,  C07D309/06 ,  C07D309/22 ,  C07D317/54 ,  C07D333/16

    CPC分类号： C07D307/42 ,  C07C403/12 ,  C07D307/28 ,  C07D309/06 ,  C07D309/22 ,  C07D317/54 ,  C07D333/16 ,  C07C2101/02 ,  C07C2101/08 ,  C07C2101/14 ,  C07C2101/16 ,  Y10S514/937 ,  Y10S514/952 ,  Y10S514/953 ,  Y10S514/957

    摘要： Novel alkynylcyclopropanecarboxylic acid esters represented by the formula, ##STR1## wherein R.sub.1 represents hydrogen, halogen, lower alkyl having up to 5 carbon atoms, lower alkenyl having up to 5 carbon atoms, lower alkynyl having up to 5 carbon atoms, C.sub.1 -C.sub.4 alkoxy C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkylthio C.sub.1 -C.sub.4 alkyl, aryl, aryl C.sub.1 -C.sub.4 alkyl, furyl, substituted furyl, thienyl, substituted thienyl, furfuryl, substituted furfuryl, thenyl, substituted thenyl, cyclo C.sub.3 -C.sub.6 alkyl, substituted cyclo C.sub.3 -C.sub.6 alkyl, cyclo C.sub.3 -C.sub.6 alkenyl or substituted cyclo C.sub.3 -C.sub.6 alkenyl; R.sub.2 and R.sub.3 individually represent hydrogen, halogen, lower alkyl having up to 5 carbon atoms, lower alkenyl having up to 5 carbon atoms, lower alkynyl having up to 5 carbon atoms, aryl, aryl C.sub.1 -C.sub.4 alkyl or may form a carbon-carbon bond; or R.sub.1 and R.sub.3 are bonded to each other at the ends to form a polymethylene chain containing or not containing an oxygen or a sulfur atom, or R.sub.1 and R.sub.2 are bonded to each other at the ends to form a polymethylene chain containing or not containing an oxygen or a sulfur atom; R.sub.4 represents hydrogen or methyl; R.sub.5 represents hydrogen, methyl, vinyl, 1-propenyl, 2-methyl-1-propenyl, 2-methoxymethyl-1-propenyl, 2-methoxycarbonyl-1-propenyl, 2,2-dichlorovinyl or cyclopentyl-idenemethyl when R.sub.4 is hydrogen, and R.sub.5 represents methyl when R.sub.4 is methyl; and R.sub.6 and R.sub.7 represent hydrogen or methyl. These novel esters are produced by reacting an alcohol or its halide or arylsulfonate of the formula, ##STR2## wherein R.sub.1, R.sub.2, R.sub.3 and R.sub.6 are defined above, and A is hydroxy, halogen or arylsulfoxy, with a cyclopropane-carboxylic acid of the formula, ##STR3## wherein R.sub.4, R.sub.5 and R.sub.7 are as defined above, or its reactive derivative. These esters are useful as an insecticide harmless to mammals.

    摘要翻译： 由式表示的新型炔基环丙烷羧酸酯，其中R 1表示氢，卤素，具有至多5个碳原子的低级烷基，具有至多5个碳原子的低级链烯基，低至5个碳原子的低级炔基，C1-C4烷氧基 C 1 -C 4烷基，C 1 -C 4烷硫基C 1 -C 4烷基，芳基，芳基C 1 -C 4烷基，呋喃基，取代的呋喃基，噻吩基，取代的噻吩基，糠基，取代的糠基，噻吩基，取代的芳基，环C 3 -C 6烷基，取代的环 C 3 -C 6烷基，环C 3 -C 6烯基或取代的环C 3 -C 6烯基; R 2和R 3各自表示氢，卤素，具有至多5个碳原子的低级烷基，具有至多5个碳原子的低级链烯基，具有至多5个碳原子的低级炔基，芳基，芳基C 1 -C 4烷基或可形成碳 - 碳 键; 或者R 1和R 3在末端彼此键合以形成含有或不含有氧原子或硫原子的多亚甲基链，或者R 1和R 2在末端彼此结合形成含有或不含有 氧或硫原子; R4代表氢或甲基; 当R4为氢时，R5代表氢，甲基，乙烯基，1-丙烯基，2-甲基-1-丙烯基，2-甲氧基甲基-1-丙烯基，2-甲氧基羰基-1-丙烯基，2,2-二氯乙烯基或环戊基 - 当R 4为甲基时，R 5表示甲基; 并且R 6和R 7表示氢或甲基。 这些新型酯通过使下式的醇或其卤化物或芳基磺酸盐与其中R1，R2，R3和R6定义如上，A是羟基，卤素或芳基磺酰基的醇或其卤化物或芳基磺酸酯与 式，其中R 4，R 5和R 7如上所定义，或其反应性衍生物。 这些酯可用作对哺乳动物无害的杀虫剂。